Disruption of Epithelial Barrier Integrity via Altered GILZ/c-Rel/RACK1 Signaling in Inflammatory Bowel Disease.

Authors: Buoso, Erica, Masi, Mirco, Limosani, Roberta Valeria, Fagiani, Francesca, Oliviero, Chiara, Colombo, Giorgia, Cari, Luigi, Gentili, Marco, Lusenti, Eleonora, Rosati, Lucrezia, Pisati, Federica, Pasini, Alessandra, Lenti, Marco Vincenzo, Sabatino, Antonio Di, Mobbs, Claire Louise, Przyborski, Stefan, Ronchetti, Simona, Travelli, Cristina, Racchi, Marco

Source: Journal of Crohn's & Colitis; Jan2025, Vol. 19, p1-17, 17p

Deficit of glucocorticoid‐induced leucine zipper amplifies angiotensin‐induced cardiomyocyte hypertrophy and diastolic dysfunction

Authors: Cappetta, Donato, De Angelis, Antonella, Flamini, Sara, Cozzolino, Anna, Bereshchenko, Oxana, Ronchetti, Simona, Cianflone, Eleonora, Gagliardi, Andrea, Ricci, Erika, Rafaniello, Concetta, Rossi, Francesco, Riccardi, Carlo, Berrino, Liberato, Bruscoli, Stefano, Urbanek, Konrad

Source: Journal of cellular and molecular medicine. 25(1):217-228

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114528017.0x000001&indx=1&recIds=ETOCvdc_100114528017.0x000001

Modulatory Effect of Cucurbitacin D from Elaeocarpus hainanensis on ZNF217 Oncogene Expression in NPM-Mutated Acute Myeloid Leukemia.

Authors: Adorisio, Sabrina, Fierabracci, Alessandra, Cham, Ba Thi, Hoang, Vu Dinh, Thuy Linh, Nguyen Thi, Nhung, Le Thi Hong, Martelli, Maria Paola, Ayroldi, Emira, Ronchetti, Simona, Rosati, Lucrezia, Di Giacomo, Silvia, Thuy, Trinh Thi, Delfino, Domenico Vittorio

Source: Pharmaceuticals (14248247); Dec2024, Vol. 17 Issue 12, p1561, 18p

Subject Terms: ACUTE myeloid leukemia, HEMATOLOGIC malignancies, MYELOID cells, CELL cycle, CANCER cells, ZINC-finger proteins

Effects of protein-protein interface disruptors at the ligand of the glucocorticoid-induced tumor necrosis factor receptor-related gene (GITR)

Authors: Platania, Chiara Bianca Maria, Ronchetti, Simona, Riccardi, Carlo, Migliorati, Graziella, Marchetti, Maria Cristina, Di Paola, Luisa, Lazzara, Francesca, Drago, Filippo, Salomone, Salvatore, Bucolo, Claudio

Source: In Biochemical Pharmacology August 2020 178

Molecular mechanisms underlying eicosapentaenoic acid inhibition of HDAC1 and DNMT expression and activity in carcinoma cells

Authors: Ceccarelli, Veronica, Ronchetti, Simona, Marchetti, Maria Cristina, Calvitti, Mario, Riccardi, Carlo, Grignani, Francesco, Vecchini, Alba

Source: In BBA - Gene Regulatory Mechanisms February 2020 1863(2)

L-GILZ binds and inhibits nuclear factor κB nuclear translocation in undifferentiated thyroid cancer cells

Authors: Marchetti, Maria Cristina, Cannarile, Lorenza, Ronchetti, Simona, Delfino, Domenico V., Riccardi, Carlo, Ayroldi, Emira

Source: Journal of chemotherapy. 32(5):263-267

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111508295.0x000001&indx=1&recIds=ETOCvdc_100111508295.0x000001

Selective CB2 inverse agonist JTE907 drives T cell differentiation towards a Treg cell phenotype and ameliorates inflammation in a mouse model of inflammatory bowel disease

Authors: Gentili, Marco, Ronchetti, Simona, Ricci, Erika, Di Paola, Rosanna, Gugliandolo, Enrico, Cuzzocrea, Salvatore, Bereshchenko, Oxana, Migliorati, Graziella, Riccardi, Carlo

Source: In Pharmacological Research March 2019 141:21-31

GILZ restrains neutrophil activation by inhibiting the MAPK pathway

Authors: Ricci, Erika, Ronchetti, Simona, Gabrielli, Elena, Pericolini, Eva, Gentili, Marco, Roselletti, Elena, Vecchiarelli, Anna, Riccardi, Carlo

Source: Journal of leukocyte biology. 105(1):187-194

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100079577385.0x000001&indx=1&recIds=ETOCvdc_100079577385.0x000001

The novel role of glucocorticoid-induced leucine zipper as a marker of mucosal healing in inflammatory bowel diseases

Authors: Leoncini, Giuseppe, Gentili, Marco, Lusenti, Eleonora, Caruso, Laura, Calafà, Cristina, Migliorati, Graziella, Riccardi, Carlo, Villanacci, Vincenzo, Ronchetti, Simona

Source: Pharmacological research. 182

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187742401.0x000001&indx=1&recIds=ETOCvdc_100187742401.0x000001

A New Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Family Inhibits T Cell Receptor-Induced Apoptosis

Authors: Nocentini, Giuseppe, Giunchi, Linda, Ronchetti, Simona, Krausz, Ludovic Tibor, Bartoli, Andrea, Moraca, Rosalba, Migliorati, Graziella, Riccardi, Carlo

Source: Proceedings of the National Academy of Sciences of the United States of America, 1997 Jun 01. 94(12), 6216-6221.

Access URL: https://www.jstor.org/stable/42337

Long glucocorticoid-induced leucine zipper regulates human thyroid cancer cell proliferation

Authors: Ayroldi, Emira, Petrillo, Maria, Marchetti, Maria, Cannarile, Lorenza, Ronchetti, Simona, Ricci, Erika, Cari, Luigi, Avenia, Nicola, Moretti, Sonia, Puxeddu, Efisio, Riccardi, Carlo

Source: Cell death and disease. 9(3):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114648539.0x000001&indx=1&recIds=ETOCvdc_100114648539.0x000001

Glucocorticoid-induced TNFR-related gene (GITR) as a therapeutic target for immunotherapy

Authors: Riccardi, Carlo, Ronchetti, Simona, Nocentini, Giuseppe

Source: Expert opinion on therapeutic targets. 22(9):783-797

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100067421260.0x000001&indx=1&recIds=ETOCvdc_100067421260.0x000001

Eicosapentaenoic acid induces DNA demethylation in carcinoma cells through a TET1‐dependent mechanism

Authors: Ceccarelli, Veronica, Valentini, Virginia, Ronchetti, Simona, Cannarile, Lorenza, Billi, Monia, Riccardi, Carlo, Ottini, Laura, Talesa, Vincenzo Nicola, Grignani, Francesco, Vecchini, Alba

Source: FASEB journal. 32(11):5990-6001

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103327454.0x000001&indx=1&recIds=ETOCvdc_100103327454.0x000001

Mucin Expression Profiles in Ulcerative Colitis: New Insights on the Histological Mucosal Healing.

Authors: Leoncini, Giuseppe, Cari, Luigi, Ronchetti, Simona, Donato, Francesco, Caruso, Laura, Calafà, Cristina, Villanacci, Vincenzo

Source: International Journal of Molecular Sciences; Feb2024, Vol. 25 Issue 3, p1858, 15p

Subject Terms: ULCERATIVE colitis, MUCINS, INFLAMMATORY bowel diseases, HEALING, SEQUENCE analysis, MEDICAL protocols

A recombinant glucocorticoid‐induced leucine zipper protein ameliorates symptoms of dextran sulfate sodium‐induced colitis by improving intestinal permeability

Authors: Gentili, Marco, Hidalgo‐Garcia, Laura, Vezza, Teresa, Ricci, Erika, Migliorati, Graziella, Rodriguez‐Nogales, Alba, Riccardi, Carlo, Galvez, Julio, Ronchetti, Simona

Source: FASEB journal. 35(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132986273.0x000001&indx=1&recIds=ETOCvdc_100132986273.0x000001

GITR+ regulatory T cells in the treatment of autoimmune diseases

Authors: Petrillo, Maria Grazia, Ronchetti, Simona, Ricci, Erika, Alunno, Alessia, Gerli, Roberto, Nocentini, Giuseppe, Riccardi, Carlo

Source: In Autoimmunity Reviews February 2015 14(2):117-126

Modulation of tumor immunity: a patent evaluation of WO2015026684A1

Authors: Nocentini, Giuseppe, Cari, Luigi, Ronchetti, Simona, Riccardi, Carlo

Source: Expert opinion on therapeutic patents. 26(3):417-425

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106706751.0x000001&indx=1&recIds=ETOCvdc_100106706751.0x000001

Glucocorticoid-Induced Tumor Necrosis Factor Receptor Family-Related Ligand Triggering Upregulates Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 and Promotes Leukocyte Adhesion

Authors: Lacal, Pedro Miguel, Petrillo, Maria Grazia, Ruffini, Federica, Muzi, Alessia, Bianchini, Rodolfo ¹, Ronchetti, Simona, Migliorati, Graziella, Riccardi, Carlo ^*, Graziani, Grazia, Nocentini, Giuseppe

Source: In The Journal of Pharmacology and Experimental Therapeutics October 2013 347(1):164-172

Anti-Inflammatory Effects of Synthetic Peptides Based on Glucocorticoid-Induced Leucine Zipper (GILZ) Protein for the Treatment of Inflammatory Bowel Diseases (IBDs).

Authors: Paglialunga, Musetta, Flamini, Sara, Contini, Raffaele, Febo, Marta, Ricci, Erika, Ronchetti, Simona, Bereshchenko, Oxana, Migliorati, Graziella, Riccardi, Carlo, Bruscoli, Stefano

Source: Cells (2073-4409); Sep2023, Vol. 12 Issue 18, p2294, 18p

Subject Terms: INFLAMMATORY bowel diseases, PEPTIDOMIMETICS, LEUCINE zippers, LYMPHOCYTE transformation, PEPTIDES

Mucosal barrier dysfunction and relapse in ulcerative colitis: Is there more that meets the eye?

Authors: Leoncini, Giuseppe, Ronchetti, Simona, Villanacci, Vincenzo

Source: In Digestive and Liver Disease August 2024 56(8):1420-1420