Consensus report on markers to distinguish procoagulant platelets from apoptotic platelets: communication from the Scientific and Standardization Committee of the ISTH

Authors: Agbani, Ejaife O., Alberio, Lorenzo, Bakchoul, Tamam, Bouchard, Beth A., Camera, Marina, Chen, Vivien, Cognasse, Fabrice, Cosemans, Judith M.E.M., Dave, Rutvi G., Denorme, Frederik, Faille, Dorothée, Goodall, Alison H., Harper, Matthew T., Heemskerk, Johan, Jobe, Shawn M., Johnson, Lacey, Kholmukhamedov, Andaleb, Mandal, Saptarshi, Kannan, Meganathan, Mezzano, Diego, Mutch, Nicola, Rand, Margaret L., Roka-Moiia, Yana, Tersteeg, Claudia, Thomas, Kimberly A., Vara, Dina, Yuan, Yuping, Josefsson, Emma C., Ramström, Sofia, Thaler, Johannes, Lordkipanidzé, Marie

Source: In Journal of Thrombosis and Haemostasis August 2023 21(8):2291-2299

Shear Stress Promotes Remodeling of Platelet Glycosylation via Upregulation of Platelet Glycosidase Activity: One More Thing.

Authors: Roka-Moiia, Yana, Lewis, Sabrina, Cleveland, Estevan, Italiano, Joseph E., Slepian, Marvin J.

Source: Thrombosis & Haemostasis; Apr2025, Vol. 125 Issue 4, p317-336, 20p

Electrical impedance vs. light transmission aggregometry: Testing platelet reactivity to antiplatelet drugs using the MICELI POC impedance aggregometer as compared to a commercial predecessor

Authors: Mencarini, Tatiana, Roka-Moiia, Yana, Bozzi, Silvia, Redaelli, Alberto, Slepian, Marvin J.

Source: In Thrombosis Research August 2021 204:66-75

Shear-mediated platelet activation in the free flow II: Evolving mechanobiological mechanisms reveal an identifiable signature of activation and a bi-directional platelet dyscrasia with thrombotic and bleeding features

Authors: Roka-Moiia, Yana, Ammann, Kaitlyn R., Miller-Gutierrez, Samuel, Sweedo, Alice, Palomares, Daniel, Italiano, Joseph, Sheriff, Jawaad, Bluestein, Danny, Slepian, Marvin J.

Source: In Journal of Biomechanics 23 June 2021 123

Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and Hemostatic Function.

Authors: Roka-Moiia, Yana¹ (AUTHOR) rokamoiia@email.arizona.edu, Ammann, Kaitlyn R.¹ (AUTHOR), Miller-Gutierrez, Samuel¹ (AUTHOR), Sheriff, Jawaad² (AUTHOR), Bluestein, Danny² (AUTHOR), Italiano, Joseph E.³ (AUTHOR), Flaumenhaft, Robert C.^3,4 (AUTHOR), Slepian, Marvin J.¹ (AUTHOR) slepian@arizona.edu

Source: International Journal of Molecular Sciences. Apr2023, Vol. 24 Issue 8, p7386. 24p.

Subject Terms: *BLOOD platelet aggregation, *BLOOD platelets, *THROMBIN receptors, *SHEARING force, *MORPHOLOGY, *TRANSMISSION electron microscopy, *HETEROGENEITY

Sodium bicarbonate as a local adjunctive agent for limiting platelet activation, aggregation, and adhesion within cardiovascular therapeutic devices.

Authors: Ammann, Kaitlyn R., Outridge, Christine E., Roka-Moiia, Yana, Muslmani, Sami, Ding, Jun, Italiano, Joseph E., Tomat, Elisa, Corbett, Scott, Slepian, Marvin J.

Source: Journal of Thrombosis & Thrombolysis; Oct2023, Vol. 56 Issue 3, p398-410, 13p

DNA Origami–Platelet Adducts: Nanoconstruct Binding without Platelet Activation.

Authors: Roka-Moiia, Yana¹ (AUTHOR) rokamoiia@email.arizona.edu, Walawalkar, Vismaya² (AUTHOR), Liu, Ying² (AUTHOR), Italiano, Joseph E.³ (AUTHOR), Slepian, Marvin J.^1,4 (AUTHOR) slepian@email.arizona.edu, Taylor, Rebecca E.^2,5 (AUTHOR) bex@andrew.cmu.edu

Source: Bioconjugate Chemistry. 7/20/2022, Vol. 33 Issue 7, p1295-1310. 16p.

Shear Stress Promotes Platelet Surface Desialylation, Platelet Count Drop, and Microvesiculation: Do Platelets Need to be Sugar-Coated?

Authors: Roka-Moiia, Yana ^*, Cleveland, Estevan ^*, Lewis, Sabrina ^*, Italiano, Joseph E., Jr., Slepian, Marvin J. ^*

Source: In Blood 15 November 2022 140 Supplement 1:5518-5519

Characterization of the competing role of surface-contact and shear stress on platelet activation in the setting of blood contacting devices.

Authors: Bozzi, Silvia, Roka-Moiia, Yana, Mencarini, Tatiana, Vercellino, Federica, Epifani, Ilenia, Ammann, Kaitlyn R, Consolo, Filippo, Slepian, Marvin J, Redaelli, Alberto

Source: International Journal of Artificial Organs; Dec2021, Vol. 44 Issue 12, p1013-1020, 8p

Shear-Mediated Platelet Activation is Accompanied by Unique Alterations in Platelet Release of Lipids.

Authors: Sweedo, Alice, Wise, Lisa M., Roka-Moiia, Yana, Arce, Fernando Teran, Saavedra, S. Scott, Sheriff, Jawaad, Bluestein, Danny, Slepian, Marvin J., Purdy, John G.

Source: Cellular & Molecular Bioengineering; Dec2021, Vol. 14 Issue 6, p597-612, 16p

Subject Terms: BLOOD platelet activation, LIPID metabolism, BLOOD platelets, HEART failure, LIPIDS, TREATMENT failure, ARACHIDONIC acid, ARTIFICIAL blood circulation

Platelet Dysfunction During Mechanical Circulatory Support: Elevated Shear Stress Promotes Downregulation of αIIbβ3 and GPIb via Microparticle Shedding Decreasing Platelet Aggregability.

Authors: Roka-Moiia, Yana, Miller-Gutierrez, Samuel, Palomares, Daniel E., Italiano, Joseph E., Sheriff, Jawaad, Bluestein, Danny, Slepian, Marvin J.

Source: Arteriosclerosis, Thrombosis & Vascular Biology; Apr2021, Vol. 41 Issue 4, p1319-1336, 18p

Impella 5.5 Versus Centrimag: A Head-to-Head Comparison of Device Hemocompatibility.

Authors: Roka-Moiia, Yana, Li, Mengtang, Ivich, Adriana, Muslmani, Sami, Kern, Karl B., Slepian, Marvin J.

Source: ASAIO Journal; Nov/Dec2020, Vol. 66 Issue 10, p1142-1151, 10p

Circulatory loop design and components introduce artifacts impacting in vitro evaluation of ventricular assist device thrombogenicity: A call for caution.

Authors: Li, Mengtang, Walk, Ryan, Roka‐Moiia, Yana, Sheriff, Jawaad, Bluestein, Danny, Barth, Eric J., Slepian, Marvin J.

Source: Artificial Organs; Jun2020, Vol. 44 Issue 6, pE226-E237, 12p

Subject Terms: HEART assist devices, BLOOD platelet activation, COMPUTATIONAL fluid dynamics, SHEARING force, PULSATILE flow, IMPACT testing

This result is not displayed to guests.
Login for full access.

Platelet Activation via Shear Stress Exposure Induces a Differing Pattern of Biomarkers of Activation versus Biochemical Agonists.

Authors: Roka-Moiia, Yana, Walk, Ryan, Palomares, Daniel E., Ammann, Kaitlyn R., Dimasi, Annalisa, Italiano, Joseph E., Sheriff, Jawaad, Bluestein, Danny, Slepian, Marvin J.

Source: Thrombosis & Haemostasis; 2020, Vol. 120 Issue 5, p776-792, 17p

The MICELI (MICrofluidic, ELectrical, Impedance): Prototyping a Point-of-Care Impedance Platelet Aggregometer.

Authors: Roka-Moiia, Yana¹ (AUTHOR) rokamoiia@email.arizona.edu, Bozzi, Silvia² (AUTHOR) silvia.bozzi@polimi.it, Ferrari, Chiara² (AUTHOR) chiara6.ferrari@mail.polimi.it, Mantica, Gabriele² (AUTHOR) gabriele.mantica@mail.polimi.it, Dimasi, Annalisa² (AUTHOR) annalisa.dimasi@polimi.it, Rasponi, Marco² (AUTHOR) marco.rasponi@polimi.it, Santoleri, Andrea² (AUTHOR) andrea.santoleri@gmail.com, Scavone, Mariangela³ (AUTHOR) mariangela.scavone@guest.unimi.it, Consolo, Filippo⁴ (AUTHOR) consolo.filippo@hsr.it, Cattaneo, Marco³ (AUTHOR) marco.cattaneo@unimi.it, Slepian, Marvin J.¹ (AUTHOR) slepian@email.arizona.edu, Redaelli, Alberto² (AUTHOR) alberto.redaelli@polimi.it

Source: International Journal of Molecular Sciences. Feb2020, Vol. 21 Issue 4, p1174. 1p. 2 Color Photographs, 1 Diagram, 3 Charts, 9 Graphs.

Subject Terms: *PLATELET-rich plasma, *BLOOD platelet aggregation, *BLOOD plasma, *BLOOD platelets, *PLATELET count, *BLOOD platelet transfusion

P83: Circulating Platelet-Derived Microparticles Modulate Platelet Adhesion Under Flow: Modeling Primary Thrombus Formation in a Microfluidic System.

Authors: Puce, Eleonora, Roka-Moiia, Yana, Mencarini, Tatiana, Bozzi, Silvia, Redaelli, Alberto, Slepian, Marvin J.

Source: ASAIO Journal; 2023Supplement, Vol. 69, p158-158, 1p

CARD12: Shear Stress Renders Redistribution of P2Y12 and PAR-1 Receptors from Platelets to Microparticles: A Cue to Limited Effectiveness of Antiplatelet Therapy in MCS.

Authors: Roka-Moiia, Yana, Ammann, Kaitlyn, Miller-Gutierrez, Samuel, Sheriff, Jawaad, Bluestein, Danny, Italiano, Joseph, Flaumenhaft, Robert, Slepian, Marvin J.

Source: ASAIO Journal; 2023Supplement, Vol. 69, p62-62, 1p

P10: Validation of the MICELI Impedance Aggregometer with ADP Lyospheres: Streamlined Protocol & Reliable Performance.

Authors: Roka-Moiia, Yana, Ammann, Kaitlyn, Scatena, Wayne, Janson, Lukas, Slepian, Marvin J.

Source: ASAIO Journal; 2022 Supplement S2, Vol. 68, p96-96, 1p

CARD8: Shear-Mediated Platelet Desialylation Promotes Reduction in Platelet Count and Increased Microvesiculation.

Authors: Roka-Moiia, Yana, Miller-Gutierrez, Samuel, Italiano, Joseph E., Slepian, Marvin J.

Source: ASAIO Journal; 2022 Supplement S2, Vol. 68, p47-47, 1p