Precision off-the-shelf natural killer cell therapies for oncology with logic-gated gene circuits

Authors: Frankel, Nicholas W., Deng, Han, Yucel, Gozde, Gainer, Marcus, Leemans, Nelia, Lam, Alice, Li, Yongshuai, Hung, Michelle, Lee, Derrick, Lee, Chen-Ting, Banicki, Andrew, Tian, Mengxi, Almudhfar, Niran, Naitmazi, Lawrence, Roguev, Assen, Lee, Seunghee, Wong, Wilson, Gordley, Russell, Lu, Timothy K., Garrison, Brian S.

Source: In Cell Reports 28 May 2024 43(5)

A Quantitative Genetic Interaction Map of HIV Infection

Authors: Gordon, David E., Watson, Ariane, Roguev, Assen, Zheng, Simin, Jang, Gwendolyn M., Kane, Joshua, Xu, Jiewei, Guo, Jeffrey Z., Stevenson, Erica, Swaney, Danielle L., Franks-Skiba, Kathy, Verschueren, Erik, Shales, Michael, Crosby, David C., Frankel, Alan D., Marson, Alexander, Marazzi, Ivan, Cagney, Gerard, Krogan, Nevan J.

Source: In Molecular Cell 16 April 2020 78(2):197-209

The Set1 complex is dimeric and acts with Jhd2 demethylation to convey symmetrical H3K4 trimethylation

Authors: Choudhury, Rupam, Singh, Sukhdeep, Arumugam, Senthil, Roguev, Assen, Stewart, A. Francis

Source: Genes & development. 33(9/10):550-564

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620201387&indx=1&recIds=ETOCRN620201387

Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells

Authors: Ding, Li, Paszkowski-Rogacz, Maciej, Winzi, Maria, Chakraborty, Debojyoti, Theis, Mirko, Singh, Sukhdeep, Ciotta, Giovanni, Poser, Ina, Roguev, Assen, Chu, Wai Kit, Choudhary, Chunaram, Mann, Matthias, Stewart, A. Francis, Krogan, Nevan, Buchholz, Frank

Source: In Cell Systems 26 August 2015 1(2):141-151

Identification of a BET Family Bromodomain/Casein Kinase II/TAF-Containing Complex as a Regulator of Mitotic Condensin Function

Authors: Kim, Hyun-Soo, Mukhopadhyay, Rituparna, Rothbart, Scott B., Silva, Andrea C., Vanoosthuyse, Vincent, Radovani, Ernest, Kislinger, Thomas, Roguev, Assen, Ryan, Colm J., Xu, Jiewei, Jahari, Harlizawati, Hardwick, Kevin G., Greenblatt, Jack F., Krogan, Nevan J., Fillingham, Jeffrey S., Strahl, Brian D., Bouhassira, Eric E., Edelmann, Winfried, Keogh, Michael-Christopher

Source: In Cell Reports 13 March 2014 6(5):892-905

Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

Authors: Ryan, Colm J., Roguev, Assen, Patrick, Kristin, Xu, Jiewei, Jahari, Harlizawati, Tong, Zongtian, Beltrao, Pedro, Shales, Michael, Qu, Hong, Collins, Sean R., Kliegman, Joseph I., Jiang, Lingli, Kuo, Dwight, Tosti, Elena, Kim, Hyun-Soo, Edelmann, Winfried, Keogh, Michael-Christopher, Greene, Derek, Tang, Chao, Cunningham, Pádraig, Shokat, Kevan M., Cagney, Gerard, Svensson, J. Peter, Guthrie, Christine, Espenshade, Peter J., Ideker, Trey, Krogan, Nevan J.

Source: In Molecular Cell 8 June 2012 46(5):691-704

Hho1p, the linker histone of Saccharomyces cerevisiae, is important for the proper chromatin organization in vivo

Authors: Georgieva, Milena, Roguev, Assen, Balashev, Konstantin, Zlatanova, Jordanka, Miloshev, George

Source: In BBA - Gene Regulatory Mechanisms May 2012 1819(5):366-374

Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast

Authors: Roguev, Assen, Bandyopadhyay, Sourav, Zofall, Martin, Zhang, Ke, Fischer, Tamas, Collins, Sean R., Qu, Hongjing, Shales, Michael, Park, Han-Oh, Hayles, Jacqueline, Hoe, Kwang-Lae, Kim, Dong-Uk, Ideker, Trey, Grewal, Shiv I., Weissman, Jonathan S., Krogan, Nevan J.

Source: Science, 2008 Oct . 322(5900), 405-410.

Access URL: https://www.jstor.org/stable/20145055

Yeast SREBP Cleavage Activation Requires the Golgi Dsc E3 Ligase Complex

Authors: Stewart, Emerson V., Nwosu, Christine C., Tong, Zongtian, Roguev, Assen, Cummins, Timothy D., Kim, Dong-Uk, Hayles, Jacqueline, Park, Han-Oh, Hoe, Kwang-Lae, Powell, David W., Krogan, Nevan J., Espenshade, Peter J.

Source: In Molecular Cell 2011 42(2):160-171

CCR4/NOT Complex Associates with the Proteasome and Regulates Histone Methylation

Authors: Laribee, R. Nicholas, Shibata, Yoichiro, Mersman, Douglas P., Collins, Sean R., Kemmeren, Patrick, Roguev, Assen, Weissman, Jonathan S., Briggs, Scott D., Krogan, Nevan J., Strahl, Brian D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2007 Apr 01. 104(14), 5836-5841.

Access URL: https://www.jstor.org/stable/25427288

Thioredoxin-related Protein 32 Is an Arsenite-regulated Thiol Reductase of the Proteasome 19 S Particle

Authors: Wiseman, R. Luke, Chin, King-Tung, Haynes, Cole M., Stanhill, Ariel, Xu, Chong-Feng, Roguev, Assen, Krogan, Nevan J., Neubert, Thomas A., Ron, David

Source: In Journal of Biological Chemistry 29 May 2009 284(22):15233-15245

Protein Moonlighting Revealed by Noncatalytic Phenotypes of Yeast Enzymes.

Authors: Espinosa-Cantú, Adriana¹, Ascencio, Diana¹, Herrera-Basurto, Selene¹, Jiewei Xu², Roguev, Assen², Krogan, Nevan J.², DeLuna, Alexander¹, alexander.deluna@cinvestav.mx

Source: Genetics; Jan2018, Vol. 208 Issue 1, p419-431, 13p, 1 Chart, 5 Graphs

Protein Interactions within the Set1 Complex and Their Roles in the Regulation of Histone 3 Lysine 4 Methylation

Authors: Dehé, Pierre-Marie, Dichtl, Bernhard, Schaft, Daniel, Roguev, Assen, Pamblanco, Mercè, Lebrun, Régine, Rodríguez-Gil, Alfonso ^**, Mkandawire, Msau, Landsberg, Katarina, Shevchenko, Anna, Shevchenko, Andrej, Rosaleny, Lorena E., Tordera, Vicente, Chávez, Sebastián ^**, Stewart, A. Francis, Géli, Vincent

Source: In Journal of Biological Chemistry 17 November 2006 281(46):35404-35412

Uncoupling of Unwinding from DNA Synthesis Implies Regulation of MCM Helicase by Tof1/Mrc1/Csm3 Checkpoint Complex

Authors: Nedelcheva, Marina N., Roguev, Assen, Dolapchiev, Luben B., Shevchenko, Andrej, Taskov, Hristo B., Shevchenko, Anna, Francis Stewart, A., Stoynov, Stoyno S. ^*

Source: In Journal of Molecular Biology 2005 347(3):509-521

The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program.

Authors: Pijnappel, W. W. M. Pim, Schaft, Daniel, Roguev, Assen

Source: Genes & Development; November 15 2001, Vol. 15 Issue 22, p2991-3004, 14p

A Comparative Analysis of an Orthologous Proteomic Environment in the Yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe

Authors: Roguev, Assen ^{‡, §}, Shevchenko, Anna ^{§, ¶}, Schaft, Daniel ^‡, Thomas, Henrik ^¶, Stewart, A. Francis ^{‡, ‖}, Shevchenko, Andrej ^{¶, ‖}

Source: In Molecular & Cellular Proteomics February 2004 3(2):125-132

Senti-202, a Selective, Off-the-Shelf, Preclinical CAR-NK Cell Therapy with CD33 and/or FLT3 Activating CAR, Healthy Cell Protection from Endomucin (EMCN) Inhibitory CAR and Calibrated Release IL-15 for Hematologic Malignancies Including AML

Authors: Garrison, Brian ^*, Deng, Han ^*, Yucel, Gozde ^*, Frankel, Nicholas W. ^*, Gordley, Russell ^*, Hung, Michelle ^*, Lee, Derrick ^*, Gainer, Marcus ^*, Roguev, Assen ^*, Gorman, Wesley ^*, Leemans, Nelia ^*, Lam, Alice ^*, Li, Yongshuai ^*, Wong, Wilson ^*, Rajangam, Kanya L., Lee, Philip ^*, Lu, Tim ^*

Source: In Blood 15 November 2022 140 Supplement 1:4531-4532

High Conservation of the Set1/Rad6 Axis of Histone 3 Lysine 4 Methylation in Budding and Fission Yeasts

Authors: Roguev, Assen ^{‡, §}, Schaft, Daniel ^{‡, §}, Shevchenko, Anna ^¶, Aasland, Rein ^{‖, **}, Shevchenko, Andrej ^¶, Stewart, A. Francis ^{‡, ‡}

Source: In Journal of Biological Chemistry 7 March 2003 278(10):8487-8493

Deciphering Protein Complexes and Protein Interaction Networks by Tandem Affinity Purification and Mass Spectrometry: Analytical Perspective

Authors: Shevchenko, Anna ^‡, Schaft, Daniel ^§, Roguev, Assen ^§, Pijnappel, W. W. M. Pim ^§, Stewart, A. Francis ^{§, ¶}, Shevchenko, Andrej ^{‡, ‖}

Source: In Molecular & Cellular Proteomics March 2002 1(3):204-212

Two-Wavelength Fluorescence Assay for DNA Repair

Authors: Roguev, Assen, Russev, George

Source: In Analytical Biochemistry 15 December 2000 287(2):313-318