5′UTR-mediated regulation of Ataxin-1 expression

Authors: Manek, Rachna, Nelson, Tiffany, Tseng, Elizabeth, Rodriguez-Lebron, Edgardo

Source: In Neurobiology of Disease February 2020 134

N-terminal sequences in matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements

Authors: Gallego-Iradi, M. Carolina, Strunk, Haley, Crown, Anthony M., Davila, Rachel, Brown, Hilda, Rodriguez-Lebron, Edgardo, Borchelt, David R.

Source: In Laboratory Investigation July 2019 99(7):1030-1040

RAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies

Authors: Croft, Cara L., Cruz, Pedro E., Ryu, Daniel H., Ceballos-Diaz, Carolina, Strang, Kevin H., Woody, Brittany M., Lin, Wen-Lang, Deture, Michael, Rodríguez-Lebrón, Edgardo, Dickson, Dennis W.

Source: Journal of experimental medicine. 216(3):539-555

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619232134&indx=1&recIds=ETOCRN619232134

Toward RNAi Therapy for the Polyglutamine Disease Machado–Joseph Disease

Authors: do Carmo Costa, Maria, Luna-Cancalon, Katiuska, Fischer, Svetlana, Ashraf, Naila S, Ouyang, Michelle, Dharia, Rahil M, Martin-Fishman, Lucas, Yang, Yemen, Shakkottai, Vikram G, Davidson, Beverly L, Rodríguez-Lebrón, Edgardo, Paulson, Henry L

Source: In Molecular Therapy October 2013 21(10):1898-1908

Silencing Mutant ATXN3 Expression Resolves Molecular Phenotypes in SCA3 Transgenic Mice

Authors: Rodríguez-Lebrón, Edgardo, Costa, Maria doCarmo, Luna-Cancalon, Katiuska, Peron, Therese M, Fischer, Svetlana, Boudreau, Ryan L, Davidson, Beverly L, Paulson, Henry L

Source: In Molecular Therapy October 2013 21(10):1909-1918

Altered Purkinje cell miRNA expression and SCA1 pathogenesis

Authors: Rodriguez-Lebron, Edgardo, Liu, Gumei, Keiser, Megan, Behlke, Mark A., Davidson, Beverly L.

Source: In Neurobiology of Disease June 2013 54:456-463

Splice isoform-specific suppression of the CaV2.1 variant underlying spinocerebellar ataxia type 6

Authors: Tsou, Wei-Ling, Soong, Bing-Wen, Paulson, Henry L., Rodríguez-Lebrón, Edgardo

Source: In Neurobiology of Disease September 2011 43(3):533-542

Ube2w and Ataxin-3 Coordinately Regulate the Ubiquitin Ligase CHIP

Authors: Scaglione, K. Matthew, Zavodszky, Eszter, Todi, Sokol V., Patury, Srikanth, Xu, Ping, Rodríguez-Lebrón, Edgardo, Fischer, Svetlana, Konen, John, Djarmati, Ana, Peng, Junmin, Gestwicki, Jason E., Paulson, Henry L.

Source: In Molecular Cell 2011 43(4):599-612

Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease

Authors: Rodríguez-Lebrón, Edgardo, Gouvion, Cynthia M, Moore, Steven A, Davidson, Beverly L, Paulson, Henry L

Source: In Molecular Therapy September 2009 17(9):1563-1573

Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo

Authors: Denovan-Wright, Eileen M., Rodriguez-Lebron, Edgardo, Lewin, Alfred S., Mandel, Ronald J.

Source: In Neurobiology of Disease 2008 29(3):446-455

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice

Authors: Rodriguez-Lebron, Edgardo, Denovan-Wright, Eileen M., Nash, Kevin, Lewin, Alfred S., Mandel, Ronald J.

Source: In Molecular Therapy October 2005 12(4):618-633

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