A semi-automated pipeline for quantifying drusen-like deposits in human induced pluripotent stem cell-derived retinal pigment epithelium cells

Authors: Jenna Hall, Maciej Daniszewski, Shane Cheung, Kalyan Shobhana, Himeesh Kumar, Helena H Liang, Henry Beetham, Ellie Cho, Carla Abbott, Alex W Hewitt, Kaylene J Simpson, Robyn H Guymer, Daniel Paull, Alice Pébay, Grace E. Lidgerwood

Source: SLAS Technology, Vol 29, Iss 3, Pp 100106- (2024)

Subject Terms: Retinal pigment epithelium, Confocal microscopy, Drusen, Age-related macular degeneration, Quantification, Reticular pseudodrusen, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2472630323000559; https://doaj.org/toc/2472-6303

Access URL: https://doaj.org/article/4a7f9281b8ca4b939616a31e76f62cde

Role of sleep-disordered breathing in age-related macular degeneration

Authors: Zhichao Wu, Chi D Luu, Robyn H Guymer, Palaniraj Rama Raj, Wendy Ying Fang, Carla Abbott, Matthew Naughton

Source: BMJ Open Ophthalmology, Vol 8, Iss 1 (2023)

Subject Terms: Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://bmjophth.bmj.com/content/8/1/e001203.full; https://doaj.org/toc/2397-3269

Access URL: https://doaj.org/article/8de19dcea67a44a7a54357a2e0ffdad9

Grand Challenges in global eye health: a global prioritisation process using Delphi method

Authors: Jacqueline Ramke, PhD, Jennifer R Evans, PhD, Esmael Habtamu, PhD, Nyawira Mwangi, PhD, Juan Carlos Silva, MD, Bonnielin K Swenor, PhD, Nathan Congdon, ProfMD, Hannah B Faal, ProfFRCOphth, Allen Foster, ProfFRCOphth, David S Friedman, ProfPhD, Stephen Gichuhi, PhD, Jost B Jonas, ProfPhD, Peng T Khaw, ProfPhD, Fatima Kyari, PhD, Gudlavalleti V S Murthy, ProfMD, Ningli Wang, ProfPhD, Tien Y Wong, ProfMD, Richard Wormald, MSc, Mayinuer Yusufu, MTI, Hugh Taylor, FRANZCO, Serge Resnikoff, ProfPhD, Sheila K West, ProfPhD, Matthew J Burton, ProfPhD, Ada Aghaji, Adeyemi T Adewole, Adrienne Csutak, Ahmad Shah Salam, Ala Paduca, Alain M Bron, Alastair K Denniston, Alberto Lazo Legua, Aldiana Halim, Alemayehu Woldeyes Tefera, Alice Mwangi, Alicia J Jenkins, Amanda Davis, Amel Meddeb-Ouertani, Amina H Wali, Ana G Palis, Ana Bastos de Carvalho, Anagha Joshi, Andreas J Kreis, Andreas Mueller, Andrew Bastawrous, Andrew Cooper, Andrew F Smith, Andrzej Grzybowski, Anitha Arvind, Anne M Karanu, Anne O Orlina, Anthea Burnett, Aryati Yashadhana, Asela P Abeydeera, Aselia Abdurakhmanova, Ashik Mohamed, Ashish Bacchav, Ashlie Bernhisel, Aubrey Walton Webson, Augusto Azuara-Blanco, Ava Hossain, Bayazit Ilhan, Bella Assumpta Lucienne, Benoit Tousignant, Bindiganavale R Shamanna, Boateng Wiafe, Brigitte Mueller, Cagatay Caglar, Caleb Mpyet, Carl H Abraham, Carol Y Cheung, Cassandra L Thiel, Catherine L Jan, Chike Emedike, Chimgee Chuluunkhuu, Chinomso Chinyere, Christin Henein, Clare E Gilbert, Covadonga Bascaran, Cristina Elena Nitulescu, Daksha Patel, Damodar Bachani, Daniel Kiage, Daniel Etya'ale, David Dahdal, Dawn Woo Lawson, Denise Godin, Dennis G Nkanga, Dennis M Ondeyo, Donna O'Brien, Dorothy M Mutie, Ebtisam S K Alalawi, Eduardo Mayorga, Effendy Bin Hashim, Elham Ashrafi, Elizabeth Andrew Kishiki, Elizabeth Kurian, Fabrizio D'Esposito, Faith Masila, Fernando Yaacov Pena, Fortunat Büsch, Fotis Topouzis, Francesco Bandello, Funmilayo J Oyediji, Gabriele Thumann, Gamal Ezz Elarab, Gatera Fiston Kitema, Gerhard Schlenther, Gertrude Oforiwa Fefoame, Gillian M Cochrane, Guna Laganovska, Haroon R Awan, Harris M Ansari, Heiko Philippin, Helen Burn, Helen Dimaras, Helena P Filipe, Henrietta I Monye, Himal Kandel, Hoby Lalaina Randrianarisoa, Iain Jones, Ian E Murdoch, Ido Didi Fabian, Imran A Khan, Indra P Sharma, Islam Elbeih, Islay Mactaggart, J Carlos Pastor, Jan E E Keunen, Jane A Ohuma, Jason Pithuwa Nirwoth, Jaouad Hammou, Jayme R Vianna, Jean-eudes Biao, Jennifer M Burr, Jeremy D Keenan, Jess Blijkers, Joanna M Black, Joao Barbosa Breda, Joao M Furtado, John C Buchan, John G Lawrenson, John H Kempen, Joshua R Ehrlich, Judith Stern, Justine H Zhang, Kadircan H Keskinbora, Karin M Knoll, Karl Blanchet, Katrina L Schmid, Koichi Ono, Kolawole Ogundimu, Komi Balo, Kussome Paulin Somda, Kwame Yeboah, Kwesi N Amissah-Arthur, Leone Nasehi, Lene Øverland, Lingam Vijaya, Lisa Keay, Lisa M Hamm, Lizette Mowatt, Lloyd C M Harrison-Williams, Lucia Silva, Luigi Bilotto, Manfred Mörchen, Mansur Rabiu, Marcia Zondervan, Margarida Chagunda, Maria Teresa Sandinha, Mariano Yee Melgar, Marisela Salas Vargas, Mark D Daniell, Marzieh Katibeh, Matt Broom, Megan E Collins, Mehmet Numan Alp, Michael A Kwarteng, Michael Belkin, Michael Gichangi, Michelle Sylvanowicz, Min Wu, Miriam R Cano, Mohammad Shalaby, Mona Duggal, Moncef Khairallah, Muhammed Batur, Mukharram M Bikbov, Muralidhar Ramappa, Nagaraju Pamarathi, Naira Khachatryan, Nasiru Muhammad, Neil Kennedy, Neil Murray, Nicholas A V Beare, Nick Astbury, Nicole A Carnt, Nigel A St Rose, Nigel H Barker, Niranjan K Pehere, Nkechinyere J Uche, Noemi Lois, Oluwaseun O Awe, Oscar J Mujica, Oteri E Okolo, Padmaja Kumari Rani, Paisan Ruamviboonsuk, Papa Amadou Ndiaye, Parami Dhakhwa, Pavel Rozsival, Pearl K Mbulawa, Pearse A Keane, Pete R Jones, Peter Holland, Phanindra Babu Nukella, Philip I Burgess, Pinar Aydin O'Dwyer, Prabhath Piyasena, Pradeep Bastola, Priya Morjaria, Qais Nasimee, Raizza A T Rambacal, Rajdeep Das, Rajiv B Khandekar, Rajvardhan Azad, Ramona Bashshur, Raúl A R C Sousa, Rebecca Oenga, Reeta Gurung, Robert Geneau, Robert J Jacobs, Robert P Finger, Robyn H Guymer, Rodica Sevciuc, Rohit C Khanna, Ronnie George, Ronnie Graham, Ryo Kawasaki, S May Ho, Sailesh Kumar Mishra, Sandeep Buttan, Sandra S Block, Sandra Talero, Sangchul Yoon, Sanil Joseph, Sare Safi, Sarity Dodson, Sergio R Munoz, Seydou Bakayoko, Seyed Farzad Mohammadi, Shabir Ahmad Muez, Shahina Pardhan, Shelley Hopkins, Shwu-Jiuan Sheu, Sidi Mohamed Coulibaly, Silvana A Schellini, Simon Arunga, Simon R Bush, Sobha Sivaprasad, Solange R Salomao, Srinivas Marmamula, Stella N Onwubiko, Stuti L Misra, Subeesh Kuyyadiyil, Sucheta Kulkarni, Sudarshan khanal, Sumrana Yasmin, Suzana Nikolic Pavljasevic, Suzanne S Gilbert, Tasanee Braithwaite, Tatiana Ghidirimschi, Thulasiraj Ravilla, Timothy R Fricke, Tiziana Cogliati, Tsehaynesh Kassa, Tunde Peto, Ute Dibb, Van C Lansingh, Victor H Hu, Victoria M Sheffield, Wanjiku Mathenge, William H Dean, Winifred Nolan, Yoshimune Hiratsuka, Yousaf Jamal Mahsood, Yuddha Sapkota

Source: The Lancet. Healthy Longevity, Vol 3, Iss 1, Pp e31-e41 (2022)

Subject Terms: Geriatrics, RC952-954.6, Medicine

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666756821003020; https://doaj.org/toc/2666-7568

Access URL: https://doaj.org/article/2b065cfdcd8540b7951cd649d9f9682e

Classification of healthy and diseased retina using SD-OCT imaging and Random Forest algorithm.

Authors: Md Akter Hussain, Alauddin Bhuiyan, Chi D Luu, R Theodore Smith, Robyn H Guymer, Hiroshi Ishikawa, Joel S Schuman, Kotagiri Ramamohanarao

Source: PLoS ONE, Vol 13, Iss 6, p e0198281 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5986153?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/610fbfd00cb04028bd63702dfd62582d

Can HMG Co-A reductase inhibitors (“statins”) slow the progression of age-related macular degeneration? The Age-Related Maculopathy Statin Study (ARMSS)

Authors: Robyn H Guymer, Peter N Dimitrov, Mary Varsamidis, Lyndell L Lim, Paul N Baird, et al

Source: Clinical Interventions in Aging, Vol Volume 3, Pp 581-593 (2008)

Subject Terms: Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://www.dovepress.com/can-hmg-co-a-reductase-inhibitors-ldquostatinsrdquo-slow-the-progressi-peer-reviewed-article-CIA; https://doaj.org/toc/1178-1998

Access URL: https://doaj.org/article/69b5d9d75107474581c3803ae3124466

Retinal changes in an ATP-induced model of retinal degeneration

Authors: Felix Peter Aplin, Kirstan Anne Vessey, Chi D Luu, Robyn H Guymer, Robert K Shepherd, Erica Lucy Fletcher

Source: Frontiers in Neuroanatomy, Vol 10 (2016)

Subject Terms: Adenosine Triphosphate, Gliosis, Photoreceptor Cells, Retina, Retinal Degeneration, Retinitis Pigmentosa, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Human anatomy, QM1-695

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fnana.2016.00046/full; https://doaj.org/toc/1662-5129

Access URL: https://doaj.org/article/9334a71c7fe24d74a8a13c630b6abb20

Association Study of Mannose-Binding Lectin Levels and Genetic Variants in Lectin Pathway Proteins with Susceptibility to Age-Related Macular Degeneration: A Case-Control Study.

Authors: Michael Osthoff, Melinda M Dean, Paul N Baird, Andrea J Richardson, Mark Daniell, Robyn H Guymer, Damon P Eisen

Source: PLoS ONE, Vol 10, Iss 7, p e0134107 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4514807?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/63f5e88d9a024c6fbc99d6c34963fa48

Age Related Macular Degeneration and Total Hip Replacement Due to Osteoarthritis or Fracture: Melbourne Collaborative Cohort Study.

Authors: Elaine W Chong, Yuanyuan Wang, Liubov D Robman, Khin Zaw Aung, Galina A Makeyeva, Graham G Giles, Stephen Graves, Flavia M Cicuttini, Robyn H Guymer

Source: PLoS ONE, Vol 10, Iss 9, p e0137322 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4565671?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0f5241f75b0b47a88cde814e9d7c1275

First-in-human trial of a novel suprachoroidal retinal prosthesis.

Authors: Lauren N Ayton, Peter J Blamey, Robyn H Guymer, Chi D Luu, David A X Nayagam, Nicholas C Sinclair, Mohit N Shivdasani, Jonathan Yeoh, Mark F McCombe, Robert J Briggs, Nicholas L Opie, Joel Villalobos, Peter N Dimitrov, Mary Varsamidis, Matthew A Petoe, Chris D McCarthy, Janine G Walker, Nick Barnes, Anthony N Burkitt, Chris E Williams, Robert K Shepherd, Penelope J Allen, Bionic Vision Australia Research Consortium

Source: PLoS ONE, Vol 9, Iss 12, p e115239 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4270734?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b9cb3c37192546c5b6a4c81a3d6f7157

Proof of concept, randomized, placebo-controlled study of the effect of simvastatin on the course of age-related macular degeneration.

Authors: Robyn H Guymer, Paul N Baird, Mary Varsamidis, Lucy Busija, Peter N Dimitrov, Khin Zaw Aung, Galina A Makeyeva, Andrea J Richardson, Lyndell Lim, Liubov D Robman

Source: PLoS ONE, Vol 8, Iss 12, p e83759 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24391822/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/af9016b6ce98442ab17214514f70a60a

Visual impairment as a function of visual acuity in both eyes and its impact on patient reported preferences.

Authors: Robert P Finger, Eva Fenwick, Christoph W Hirneiss, Arthur Hsueh, Robyn H Guymer, Ecosse L Lamoureux, Jill E Keeffe

Source: PLoS ONE, Vol 8, Iss 12, p e81042 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24339893/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/49d23c1ae4b74edaac8bb10a5416d2f8

Comprehensive analysis of Copy Number Variation of genes at chromosome 1 and 10 loci associated with late age related macular degeneration.

Authors: Stuart Cantsilieris, Stefan J White, Andrea J Richardson, Robyn H Guymer, Paul N Baird

Source: PLoS ONE, Vol 7, Iss 4, p e35255 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22558131/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/7fefbd834efd40919740412dd0db20fd

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Retrospective audit reviewing accuracy of clinical diagnosis of geographic atrophy in a single centre private tertiary retinal practice in Australia

Authors: Demi Markakis, Alexis Ceecee Britten-Jones, Robyn H. Guymer, Thomas L. Edwards, Anthony J. Hall, Nathan M. Kerr, Weng Ng, Simon Skalicky, Lauren N. Ayton, Heather G. Mack

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-11 (2025)

Subject Terms: Age-related macular degeneration, Macular atrophy, Inherited retinal disease, Clinical audit, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/7821fbdc6b114c0da7bd0c9a2580b667

Monoclonal antibody to ICAM-1 prolongs murine heterotopic corneal allograft survival.

Authors: BS, Robyn H. Guymer MB, BS, T. E. Mandel MB

Source: Australian & New Zealand Journal of Ophthalmology; 1991, Vol. 19 Issue 2, p141-144, 4p

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Current advances in multimodal imaging in geographic atrophy secondary to age-related macular degeneration: A review

Authors: Amy C. Cohn, Robyn H. Guymer

Source: Taiwan Journal of Ophthalmology, Vol 14, Iss 4, Pp 464-472 (2024)

Subject Terms: geographic atrophy, age-related macular degeneration, complement inhibition, imaging, auto-fluorescence, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://journals.lww.com/10.4103/tjo.TJO-D-24-00065; https://doaj.org/toc/2211-5056; https://doaj.org/toc/2211-5072

Access URL: https://doaj.org/article/04f7db11ca374adb965db99277316c93

Nanosecond laser induces proliferation and improved cellular health within the retinal pigment epithelium

Authors: Andrew I. Jobling, Quan Findlay, Ursula Greferath, Kirstan A. Vessey, Satya Gunnam, Victoria Morrison, Gene Venables, Robyn H. Guymer, Erica L. Fletcher

Source: Frontiers in Medicine, Vol 12 (2025)

Subject Terms: age related macular degeneration, nanosecond laser, retinal pigment epithelium, proliferation, aging, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2025.1516900/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/1e16951df7a3436c83237713e8c340b8

Reticular Pseudodrusen

Authors: Himeesh Kumar, MBBS(Hons), PhD, Robyn H. Guymer, MBBS, PhD, Lauren A.B. Hodgson, MPH, Xavier Hadoux, MEng, PhD, Maxime Jannaud, MEng, Peter van Wijngaarden, MBBS(Hons), PhD, Chi D. Luu, PhD, Zhichao Wu, BAppSc(Optom), PhD

Source: Ophthalmology Science, Vol 4, Iss 6, Pp 100551- (2024)

Subject Terms: Age-related macular degeneration, Reticular pseudodrusen, Dark adaptation, Rod photoreceptors, Drusen, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666914524000873; https://doaj.org/toc/2666-9145

Access URL: https://doaj.org/article/45818352ac754f2dbbb7a9f67a275486

Decreased Circulating Very Small Low-Density Lipoprotein is Likely Causal for Age-Related Macular Degeneration

Authors: Samaneh Farashi, PhD, Roberto Bonelli, PhD, Victoria E. Jackson, PhD, Brendan R.E. Ansell, PhD, Robyn H. Guymer, MBBS, PhD, Melanie Bahlo, PhD

Source: Ophthalmology Science, Vol 4, Iss 5, Pp 100535- (2024)

Subject Terms: Age-related macular degeneration, Circulating metabolites, Genome-wide association studies, Mendelian randomization, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266691452400071X; https://doaj.org/toc/2666-9145

Access URL: https://doaj.org/article/4949a2d6ad3349d8b64d6aee8dc84272