Downregulation of miRNA-26a by HIV-1 Enhances CD59 Expression and Packaging, Impacting Virus Susceptibility to Antibody-Dependent Complement-Mediated Lysis

Authors: Nicolas Bellini, Chengyu Ye, Oluwaseun Ajibola, Thomas T. Murooka, Robert Lodge, Éric A. Cohen

Source: Viruses, Vol 16, Iss 7, p 1076 (2024)

Subject Terms: CD59, HIV-1, complement-mediated lysis, miRNA-26a, innate immunity, viral evasion, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/7/1076; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/98ea85c54eba4a34b070bb0e76291d42

MicroRNA-25/93 induction by Vpu as a mechanism for counteracting MARCH1-restriction on HIV-1 infectivity in macrophages

Authors: Robert Lodge, Zaikun Xu, Mckenna Eklund, Christina Stürzel, Frank Kirchhoff, Michel J. Tremblay, Tom C. Hobman, Éric A. Cohen

Source: mBio, Vol 14, Iss 5 (2023)

Subject Terms: human immunodeficiency virus, microRNA, restriction factor, viral glycoproteins, MARCH proteins, HIV-1 countermeasures, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/d691c612579c4ccfb0b25dd7e74b1bb7

MiRNA-103 downmodulates CCR5 expression reducing human immunodeficiency virus type-1 entry and impacting latency establishment in CD4+ T cells

Authors: Nicolas Bellini, Robert Lodge, Tram N.Q. Pham, Jaspreet Jain, Thomas T. Murooka, Alon Herschhorn, Nicole F. Bernard, Jean-Pierre Routy, Cécile L. Tremblay, Éric A. Cohen

Source: iScience, Vol 25, Iss 10, Pp 105234- (2022)

Subject Terms: Biological sciences, molecular biology, immunology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222015061; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/30d4e7980f46475a9a5b3a72a2a0365d

Interleukin-1β Triggers p53-Mediated Downmodulation of CCR5 and HIV-1 Entry in Macrophages through MicroRNAs 103 and 107

Authors: Robert Lodge, Nicolas Bellini, Mélanie Laporte, Syim Salahuddin, Jean-Pierre Routy, Petronela Ancuta, Cecilia T. Costiniuk, Mohammad-Ali Jenabian, Éric A. Cohen

Source: mBio, Vol 11, Iss 5 (2020)

Subject Terms: alveolar macrophage, CCR5, CD4, colon macrophage, HIV reservoir, IL-1β, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/bf3c9c672de24376b80f6cc1733e60a9

The HIV-1 Accessory Protein Vpu Downregulates Peroxisome Biogenesis

Authors: Zaikun Xu, Robert Lodge, Christopher Power, Eric A. Cohen, Tom C. Hobman

Source: mBio, Vol 11, Iss 2 (2020)

Subject Terms: HIV, Vpu, peroxisomes, miRNAs, β-catenin, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/006b52600c4f4fdaae933574a259397e

Host MicroRNAs-221 and -222 Inhibit HIV-1 Entry in Macrophages by Targeting the CD4 Viral Receptor

Authors: Robert Lodge, Jérémy A. Ferreira Barbosa, Félix Lombard-Vadnais, Julian C. Gilmore, Alexandre Deshiere, Annie Gosselin, Tomas Raul Wiche Salinas, Mariana G. Bego, Christopher Power, Jean-Pierre Routy, Petronela Ancuta, Michel J. Tremblay, Éric A. Cohen

Source: Cell Reports, Vol 21, Iss 1, Pp 141-153 (2017)

Subject Terms: HIV-1, macrophage, microRNA, TNF-α, macrophage activation, CD4, miR-221, miR-222, antiviral, RNA-seq, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717313050; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/b79fa5ac2bb9497c9de47770d7042beb

Global Mapping of the Macrophage-HIV-1 Transcriptome Reveals that Productive Infection Induces Remodeling of Host Cell DNA and Chromatin

Authors: Alexandre Deshiere, Charles Joly-Beauparlant, Yann Breton, Michel Ouellet, Frédéric Raymond, Robert Lodge, Corinne Barat, Marc-André Roy, Jacques Corbeil, Michel J. Tremblay

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ea2329ad91314c6c8c74950e07bd5937

Regulation of CD4 Receptor and HIV-1 Entry by MicroRNAs-221 and -222 during Differentiation of THP-1 Cells

Authors: Robert Lodge, Julian C. Gilmore, Jérémy A. Ferreira Barbosa, Félix Lombard-Vadnais, Éric A. Cohen

Source: Viruses, Vol 10, Iss 1, p 13 (2017)

Subject Terms: microRNA, miR-221, miR-222, THP-1 cell line, macrophage, monocyte, cluster of differentiation 4 (CD4), RNAseq, human immunodeficiency virus type-1 (HIV-1), Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/10/1/13; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/daba3da829ab4ff281c015b3f95b118a

HIV-1 promotes intake of Leishmania parasites by enhancing phosphatidylserine-mediated, CD91/LRP-1-dependent phagocytosis in human macrophages.

Authors: Robert Lodge, Michel Ouellet, Corinne Barat, Guadalupe Andreani, Pranav Kumar, Michel J Tremblay

Source: PLoS ONE, Vol 7, Iss 3, p e32761 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3295765?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d4170db6758d4eaf8e56e05fefe08e4a

Nelfinavir, an HIV-1 protease inhibitor, induces oxidative stress-mediated, caspase-independent apoptosis in Leishmania amastigotes.

Authors: Pranav Kumar, Robert Lodge, Nathalie Trudel, Michel Ouellet, Marc Ouellette, Michel J Tremblay

Source: PLoS Neglected Tropical Diseases, Vol 4, Iss 3, p e642 (2010)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2846936?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/5cf93f0845184465b43da0ff36e6f2e4

Leishmania infantum amastigotes enhance HIV-1 production in cocultures of human dendritic cells and CD4 T cells by inducing secretion of IL-6 and TNF-alpha.

Authors: Ravendra Garg, Corinne Barat, Michel Ouellet, Robert Lodge, Michel J Tremblay

Source: PLoS Neglected Tropical Diseases, Vol 3, Iss 5, p e441 (2009)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2680485?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/4daaf7d5a02647a1b1a3c97fdc6d5c6e

An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells

Authors: Guadalupe Andreani, author¹, Dominic Gagnon, author¹, Robert Lodge, author¹, Michel J. Tremblay, author¹, Dave Richard, author¹

Source: Journal of Visualized Experiments. (66)

Availability: http://www.jove.com/video/4166

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Enhancing Elder Chronic Care through Technology and Care Coordination: Report from a Pilot.

Authors: Rita Kobb, Nannette Hoffman, Robert Lodge, Sheri Kline

Source: Telemedicine & e-Health; Jun2003, Vol. 9 Issue 2, p189-195, 7p

Subject Terms: CHRONIC diseases, MEDICAL care

Geographic Terms: UNITED States

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Distinct mechanisms of agonist-induced endocytosis for human chemokine receptors CCR5 and CXCR4.

Authors: Sundararajan, Venkatesan, J, Rose Jeremy, Robert, Lodge, M, Murphy Philip, F, Foley John

Source: Molecular Biology of the Cell; August 2003, Vol. 14 Issue: 8 p3305-24, 20p

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