Prognostic Impact and Spatial Interplay of Immune Cells in Urothelial Cancer

Authors: Debatin, Nicolaus F., Bady, Elena, Mandelkow, Tim, Huang, Zhihao, Lurati, Magalie C.J., Raedler, Jonas B., Müller, Jan H., Vettorazzi, Eik, Plage, Henning, Samtleben, Henrik, Klatte, Tobias, Hofbauer, Sebastian, Elezkurtaj, Sefer, Furlano, Kira, Weinberger, Sarah, Giacomo Bruch, Paul, Horst, David, Roßner, Florian, Schallenberg, Simon, Marx, Andreas H., Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten H., Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Lennartz, Maximilian, Minner, Sarah, Simon, Ronald, Sauter, Guido, Zecha, Henrik, Schlomm, Thorsten, Blessin, Niclas C.

Source: In European Urology July 2024 86(1):42-51

Robot-Assisted Laparoscopic Prostatectomy Experience and Pathological Quality: Are They Always Linked?

Authors: Altaylouni, Turki, Gebert, Pimrapat, Elezkurtaj, Sefer, Rossner, Florian, Ralla, Bernhard, Weinberger, Sarah, Moldovan, Diana, Schlomm, Thorsten, Guillonneau, Bertrand

Source: Journal of endourology. 37(9):995-1000

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191756627.0x000001&indx=1&recIds=ETOCvdc_100191756627.0x000001

DNA methylation-based classifier differentiates intrahepatic pancreato-biliary tumours

Authors: Dragomir, Mihnea P., Calina, Teodor G., Perez, Eilís, Schallenberg, Simon, Chen, Meng, Albrecht, Thomas, Koch, Ines, Wolkenstein, Peggy, Goeppert, Benjamin, Roessler, Stephanie, Calin, George A., Sers, Christine, Horst, David, Roßner, Florian, Capper, David

Source: In eBioMedicine July 2023 93

Cytokeratin 20 expression is linked to stage progression and to poor prognosis in advanced (pT4) urothelial carcinoma of the bladder

Authors: Bruch, Paul Giacomo, Plage, Henning, Hofbauer, Sebastian, Kornienko, Kira, Weinberger, Sarah, Roßner, Florian, Schallenberg, Simon, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Minner, Sarah, Simon, Ronald, Sauter, Guido, Zecha, Henrik, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Elezkurtaj, Sefer

Source: In Experimental and Molecular Pathology June 2023 131

GATA3 expression loss is linked to stage progression but is unrelated to prognosis in muscle-invasive urothelial carcinoma of the bladder

Authors: Plage, Henning, Samtleben, Henrik, Hofbauer, Sebastian, Kornienko, Kira, Weinberger, Sarah, Bruch, Paul Giacomo, Elezkurtaj, Sefer, Roßner, Florian, Schallenberg, Simon, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan, Adamini, Nico, Minner, Sarah, Simon, Ronald, Sauter, Guido, Klatte, Tobias, Schlomm, Thorsten, Horst, David, Zecha, Henrik

Source: In Human Pathology December 2022 130:10-17

Loss of MTAP expression is strongly linked to homozygous 9p21 deletion, unfavorable tumor phenotype, and noninflamed microenvironment in urothelial bladder cancer.

Authors: Gorbokon, Natalia, Wößner, Niklas, Ahlburg, Viktoria, Plage, Henning, Hofbauer, Sebastian, Furlano, Kira, Weinberger, Sarah, Bruch, Paul Giacomo, Schallenberg, Simon, Roßner, Florian, Elezkurtaj, Sefer, Lennartz, Maximilian, Blessin, Niclas C, Marx, Andreas H, Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten

Source: Journal of Pathology: Clinical Research; Jan2025, Vol. 11 Issue 1, p1-13, 13p

Reduced p63 expression is linked to unfavourable prognosis in muscle‐invasive urothelial carcinoma of the bladder.

Authors: Furlano, Kira, Plage, Henning, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Fendler, Annika, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Koch, Stefan

Source: BJUI Compass; Nov2024, Vol. 5 Issue 11, p1081-1089, 9p

Pathology of Combined Hepatocellular Carcinoma-Cholangiocarcinoma: An Update.

Authors: Roßner, Florian¹ (AUTHOR) florian.rossner@charite.de, Sinn, Bruno Valentin¹ (AUTHOR), Horst, David^1,2 (AUTHOR)

Source: Cancers. Jan2023, Vol. 15 Issue 2, p494. 28p.

Subject Terms: *CANCER cells, *STAINS & staining (Microscopy), *CHOLANGIOCARCINOMA, *IMMUNOHISTOCHEMISTRY, *HEPATOCELLULAR carcinoma

17p13 (TP53) Deletions Are Associated With an Aggressive Phenotype but Unrelated to Patient Prognosis in Urothelial Bladder Carcinomas.

Authors: Kluth, Martina, Hitzschke, Melanie, Furlano, Kira, Plage, Henning, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Fendler, Annika, de Martino, Michela, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Lennartz, Maximilian, Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten

Source: Genes, Chromosomes & Cancer; Sep2024, Vol. 63 Issue 9, p1-9, 9p

Tspan8 is expressed in breast cancer and regulates E‐cadherin/catenin signalling and metastasis accompanied by increased circulating extracellular vesicles

Authors: Voglstaetter, Maren, Thomsen, Andreas R, Nouvel, Jerome, Koch, Arend, Jank, Paul, Navarro, Elena Grueso, Gainey‐Schleicher, Tanja, Khanduri, Richa, Groß, Andrea, Rossner, Florian, Blaue, Carina, Franz, Clemens M, Veil, Marina, Puetz, Gerhard, Hippe, Andreas, Dindorf, Jochen, Kashef, Jubin, Thiele, Wilko, Homey, Bernhard, Greco, Celine, Boucheix, Claude, Baur, Andreas, Erbes, Thalia, Waller, Cornelius F, Follo, Marie, Hossein, Ghamartaj, Sers, Christine, Sleeman, Jonathan, Nazarenko, Irina

Source: Journal of pathology. 248(4):421-437

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085909929.0x000001&indx=1&recIds=ETOCvdc_100085909929.0x000001

CEA (CEACAM5) expression is common in muscle‐invasive urothelial carcinoma of the bladder but unrelated to the disease course.

Authors: Plage, Henning, Furlano, Kira, Neymeyer, Jörg, Weinberger, Sarah, Gerdes, Benedikt, Hubatsch, Mandy, Ralla, Bernhard, Franz, Antonia, Fendler, Annika, de Martino, Michela, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael

Source: BJUI Compass; Jun2024, Vol. 5 Issue 6, p585-592, 8p

PD-L1 expression in tumor and inflammatory cells is associated with favorable tumor features and favorable prognosis in muscle-invasive urothelial carcinoma of the bladder not treated by immune checkpoint inhibitors.

Authors: Plage, Henning, Furlano, Kira, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Franz, Antonia, Fendler, Annika, de Martino, Michela, Roßner, Florian, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten

Source: BMC Urology; 4/24/2024, Vol. 24 Issue 1, p1-9, 9p

Subject Terms: BLADDER cancer, IMMUNE checkpoint inhibitors, TRANSITIONAL cell carcinoma, PROGRAMMED death-ligand 1, KI-67 antigen, IPILIMUMAB, PROGNOSIS, BLADDER

Alterations of mTOR signaling impact metabolic stress resistance in colorectal carcinomas with BRAF and KRAS mutations

Authors: Fritsche-Guenther, Raphaela, Zasada, Christin, Mastrobuoni, Guido, Royla, Nadine, Rainer, Roman, Roßner, Florian, Pietzke, Matthias, Klipp, Edda, Sers, Christine, Kempa, Stefan

Source: Scientific reports. 8(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171407541.0x000001&indx=1&recIds=ETOCvdc_100171407541.0x000001

Loss of TROP2 and epithelial cell adhesion molecule expression is linked to grade progression in pTa but unrelated to disease outcome in pT2-4 urothelial bladder carcinomas.

Authors: Müller, Jan H., Plage, Henning, Elezkurtaj, Sefer, Mandelkow, Tim, Zhihao Huang, Lurati, Magalie C. J., Raedler, Jonas B., Debatin, Nicolaus F., Vettorazzi, Eik, Samtleben, Henrik, Hofbauer, Sebastian, Furlano, Kira, Neymeyer, Jörg, Goranova, Irena, Ralla, Bernhard, Weinberger, Sarah, Horst, David, Roßner, Florian, Schallenberg, Simon, Marx, Andreas H.

Source: Frontiers in Oncology; 2024, p1-10, 10p

Subject Terms: CELL adhesion molecules, TRANSITIONAL cell carcinoma, BLADDER cancer, CELL surface antigens, EPITHELIAL cells, ANTIBODY-drug conjugates

Loss of Upk1a and Upk1b expression is linked to stage progression in urothelial carcinoma of the bladder.

Authors: Kaczmarek, Krystian, Plage, Henning, Furlano, Kira, Hofbauer, Sebastian, Weinberger, Sarah, Ralla, Bernhard, Franz, Antonia, Fendler, Annika, de Martino, Michela, Roßner, Florian, Schallenberg, Simon, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin

Source: International Urology & Nephrology; Feb2024, Vol. 56 Issue 2, p499-508, 10p

CD271 determines migratory properties of melanoma cells

Authors: Radke, Josefine, Roßner, Florian, Redmer, Torben

Source: Scientific reports. 7(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178388249.0x000001&indx=1&recIds=ETOCvdc_100178388249.0x000001

Altered p53/p16 expression is linked to urothelial carcinoma progression but largely unrelated to prognosis in muscle-invasive tumors.

Authors: Schallenberg, Simon, Plage, Henning, Hofbauer, Sebastian, Furlano, Kira, Weinberger, Sarah, Bruch, Paul Giacomo, Roßner, Florian, Elezkurtaj, Sefer, Kluth, Martina, Lennartz, Maximilian, Blessin, Niclas C., Marx, Andreas H., Samtleben, Henrik, Fisch, Margit, Rink, Michael, Slojewski, Marcin, Kaczmarek, Krystian, Ecke, Thorsten, Hallmann, Steffen, Koch, Stefan

Source: Acta Oncologica; Dec2023, Vol. 62 Issue 12, p1880-1889, 10p

Subject Terms: BLADDER tumors, DISEASE progression, TISSUE arrays, GENETIC mutation, STAINS & staining (Microscopy), ONCOGENES, CANCER invasiveness, MUSCLES, IMMUNOHISTOCHEMISTRY, GENE expression, RISK assessment, TRANSITIONAL cell carcinoma, CANCER patients, DESCRIPTIVE statistics, TUMOR markers

How to Estimate the Probability of Tolerance Long-Term in Liver Transplant Recipients.

Authors: Eurich, Dennis, Schlickeiser, Stephan, Ossami Saidy, Ramin Raul, Uluk, Deniz, Rossner, Florian, Postel, Maximilian, Schoening, Wenzel, Oellinger, Robert, Lurje, Georg, Pratschke, Johann, Reinke, Petra, Gruen, Natalie

Source: Journal of Clinical Medicine; Oct2023, Vol. 12 Issue 20, p6546, 14p

Subject Terms: LIVER transplantation, KIDNEY transplantation, LOGISTIC regression analysis, PROBABILITY theory, MULTIVARIABLE testing, HEPATOCELLULAR carcinoma

Unerwünschte Wirkungen auf ein injiziertes Polymilchsäurepräparat :Ergebnisse der Injectable-Filler-Safety-Studie
Adverse effects on an injected polymilk acid preparation: Results of the Injectable Filler-Safety Study

Authors: Roßner, Florian

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_Z6GMQAKSNLBL4A6OESSL4OQCQMTKPHYJ

The Diagnostic Approach towards Combined Hepatocellular-Cholangiocarcinoma—State of the Art and Future Perspectives.

Authors: Eschrich, Johannes, Kobus, Zuzanna, Geisel, Dominik, Halskov, Sebastian, Roßner, Florian, Roderburg, Christoph, Mohr, Raphael, Tacke, Frank

Source: Cancers; Jan2023, Vol. 15 Issue 1, p301, 13p

Subject Terms: ALPHA fetoproteins, CHOLANGIOCARCINOMA, ARTIFICIAL intelligence, UNCERTAINTY, TUMOR markers, BODY fluid examination, TUMOR antigens, SENSITIVITY & specificity (Statistics), HEPATOCELLULAR carcinoma