Probing Unexpected Reactivity in Radiometal Chemistry: Indium-111-Mediated Hydrolysis of Hybrid Cyclen-Hydroxypyridinone Ligands

Authors: Rivas, Charlotte, Jackson, Jessica A., Rigby, Alex, Jarvis, James A., White, Andrew J. P., Blower, Philip J., Phanopoulos, Andreas, Ma, Michelle T.

Source: Inorganic chemistry. 62(13):5270-5281

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Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal

Authors: Hao, Xiaoxin, Shen, Yichao, Chen, Nan, Zhang, Weijie, Valverde, Elizabeth, Wu, Ling, Chan, Hilda L., Xu, Zhan, Yu, Liqun, Gao, Yang, Bado, Igor, Michie, Laura Natalee, Rivas, Charlotte Helena, Dominguez, Luis Becerra, Aguirre, Sergio, Pingel, Bradley C., Wu, Yi-Hsuan, Liu, Fengshuo, Ding, Yunfeng, Edwards, David G., Liu, Jun, Alexander, Angela, Ueno, Naoto T., Hsueh, Po-Ren, Tu, Chih-Yen, Liu, Liang-Chih, Chen, Shu-Hsia, Hung, Mien-Chie, Lim, Bora, Zhang, Xiang H.-F.

Source: In Cell Stem Cell 4 May 2023 30(5):648-664

Toward Bifunctional Chelators for Thallium-201 for Use in Nuclear Medicine

Authors: Rigby, Alex, Firth, George, Rivas, Charlotte, Pham, Truc, Kim, Jana, Phanopoulos, Andreas, Wharton, Luke, Ingham, Aidan, Li, Lily, Ma, Michelle T.

Source: Bioconjugate chemistry. 33(7):1422-1436

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Synthesis and in vivo behaviour of an exendin-4-based MRI probe capable of β-cell-dependent contrast enhancement in the pancreasElectronic supplementary information (ESI) available: Figures showing glycaemic levels of βDicer-control and βDicer-null mice, characterisation data for the ligand, 1 and probe GdEx and additional MRI images showing the pancreas. See DOI: 10.1039/d0dt00332h

Authors: Clough, Thomas J., Baxan, Nicoleta, Coakley, Emma J., Rivas, Charlotte, Zhao, Lan, Leclerc, Isabelle, Martinez-Sanchez, Aida, Rutter, Guy A., Long, Nicholas J.

Source: Dalton transactions. 49(15):4732-4740

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Bioconjugates of Chelators with Peptides and Proteins in Nuclear Medicine: Historical Importance, Current Innovations, and Future Challenges

Authors: Jackson, Jessica A., Hungnes, Ingebjørg N., Ma, Michelle T., Rivas, Charlotte

Source: Bioconjugate chemistry. 31(3):483-491

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Receptor-Targeted Peptide Conjugates Based on Diphosphines Enable Preparation of ^99mTc and ¹⁸⁸Re Theranostic Agents for Prostate Cancer.

Authors: Pham, Truc T., Hungnes, Ingebjørg N., Rivas, Charlotte, Cleaver, Julie, Firth, George, Blower, Philip J., Sosabowski, Jane, Cook, Gary J. R., Livieratos, Lefteris, Young, Jennifer D., Pringle, Paul G., Ma, Michelle T.

Source: Journal of Nuclear Medicine; Jul2024, Vol. 65 Issue 7, p1087-1094, 8p

P-248 - Dual labelling platform for theranostics: PSMA-targeted imaging with 99mTc and therapy with 188Re

Authors: Hungnes, Ingebjorg, Pham, Truc, Rivas, Charlotte, Firth, George, Jarvis, James, Young, Jennifer, Pringle, Paul, Blower, Phil, Ma, Michelle

Source: In Nuclear Medicine and Biology November-December 2023 126-127 Supplement

Diphosphine bifunctional chelators: [99mTc][TcO2(DP-PSMAt)2]+ tracers for PSMA imaging of prostate cancer

Authors: Hungnes, Ingebjorg, Pham, Truc, Rivas, Charlotte, Firth, George, Jarvis, James, Young, Jennifer, Blower, Phil, Pringle, Paul, Ma, Michelle

Source: Nuclear medicine and biology. 114(S):S5-S6

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Versatile Diphosphine Chelators for Radiolabeling Peptides with ^99mTc and ⁶⁴Cu.

Authors: Hungnes, Ingebjørg N., Pham, Truc Thuy, Rivas, Charlotte, Jarvis, James A., Nuttall, Rachel E., Cooper, Saul M., Young, Jennifer D., Blower, Philip J., Pringle, Paul G., Ma, Michelle T.

Source: Inorganic Chemistry; 12/18/2023, Vol. 62 Issue 50, p20608-20620, 13p

A novel sialidase-activatable fluorescence probe with improved stability for the sensitive detection of sialidase

Authors: Rivas, Charlotte, Kamiya, Mako, Urano, Yasuteru

Source: Bioorganic & medicinal chemistry letters. 30(2)

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Versatile Diphosphine Chelators for Radiolabeling Peptides with 99mTc and 64Cu

Authors: Hungnes, Ingebjørg N., Pham, Truc Thuy, Rivas, Charlotte, Jarvis, James A., Nuttall, Rachel E., Cooper, Saul M., Young, Jennifer D., Blower, Philip J., Pringle, Paul G., Ma, Michelle T.

Source: Inorganic Chemistry; December 2023, Vol. 62 Issue: 50 p20608-20620, 13p

TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy

Authors: Jayaraman, Padmini, Parikh, Falguni, Newton, Jared M., Hanoteau, Aurelie, Rivas, Charlotte, Krupar, Rosemarie, Rajapakshe, Kimal, Pathak, Ravi, Kanthaswamy, Kavin, MacLaren, Cassie, Huang, Shixia, Coarfa, Cristian, Spanos, Chad, Edwards, Dean P., Parihar, Robin, Sikora, Andrew G.

Source: Oncoimmunology. 7(10)

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O-13 - Towards bifunctional chelators for thallium-201 for use in nuclear medicine

Authors: Rigby, Alex, Firth, George, Rivas, Charlotte, Pham, Truc, Kim, Jana, Phanopoulos, Andreas, Wharton, Luke, Ingham, Aidan, Li, Lily, Ma, Michelle, Orvig, Chris, Blower, Phil, Terry, Samantha, Abbate, Vincenzo

Source: In Nuclear Medicine and Biology November-December 2022 114-115 Supplement:S10-S10

O-05 - Diphosphine bifunctional chelators: [99mTc][TcO2(DP-PSMAt)2]+ tracers for PSMA imaging of prostate cancer

Authors: Hungnes, Ingebjorg, Pham, Truc, Rivas, Charlotte, Firth, George, Jarvis, James, Young, Jennifer, Blower, Phil, Pringle, Paul, Ma, Michelle

Source: In Nuclear Medicine and Biology November-December 2022 114-115 Supplement:S5-S6

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Radioactive Metals in Imaging and Therapy

Authors: Rivas, Charlotte, Jackson, Jessica A., Hungnes, Ingebjørg N., Ma, Michelle T.

Source: In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering 2013

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