Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression

Authors: Noelia Lozano-Vidal, Laura Stanicek, Diewertje I. Bink, Rio P. Juni, Aukie Hooglugt, Veerle Kremer, Philippa Phelp, Anke van Bergen, Alyson W. MacInnes, Stefanie Dimmeler, Reinier A. Boon

Source: Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/c23b2adb9f504a019c2402bcb783687d

HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice

Authors: Alessandra Tammaro, Eileen G. Daniels, Iman M. Hu, Kelly C. ‘t Hart, Kim Reid, Rio P. Juni, Loes M. Butter, Goutham Vasam, Rashmi Kamble, Aldo Jongejan, Richard I. Aviv, Joris J.T.H. Roelofs, Eleonora Aronica, Reinier A. Boon, Keir J. Menzies, Riekelt H. Houtkooper, Georges E. Janssens

Source: iScience, Vol 27, Iss 1, Pp 108681- (2024)

Subject Terms: Drugs, Molecular biology, Epigenetics, Omics, Transcriptomics, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S258900422302758X; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/42cc145abf8d478f88355c37c49e69d9

Non-coding RNAs in the pathophysiology of heart failure with preserved ejection fraction

Authors: Elisabeth A. Jalink, Amber W. Schonk, Reinier A. Boon, Rio P. Juni

Source: Frontiers in Cardiovascular Medicine, Vol 10 (2024)

Subject Terms: HFpEF, HFpEF pathophysiology, non-coding RNAs: miRNAs, lncRNAs, circRNAs, biomarkers, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1300375/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/dd0fbfee4e90401bac94aaf8453bc925

Empagliflozin and Dapagliflozin Reduce ROS Generation and Restore NO Bioavailability in Tumor Necrosis Factor α-Stimulated Human Coronary Arterial Endothelial Cells

Authors: Laween Uthman, Anna Homayr, Rio P. Juni, Eva L. Spin, Raphaela Kerindongo, Marleen Boomsma, Markus W. Hollmann, Benedikt Preckel, Pieter Koolwijk, Victor W.M. van Hinsbergh, Coert J. Zuurbier, Martin Albrecht, Nina C. Weber

Source: Cellular Physiology and Biochemistry, Vol 53, Iss 5, Pp 865-886 (2019)

Subject Terms: Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.cellphysiolbiochem.com/Articles/000178/; https://doaj.org/toc/1015-8987

Access URL: https://doaj.org/article/233c649f9b894beab1e1f03e1375d2bb

Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin

Authors: Rio P. Juni, PhD, Diederik W.D. Kuster, PhD, Max Goebel, MSc, Michiel Helmes, PhD, René J.P. Musters, PhD, Jolanda van der Velden, PhD, Pieter Koolwijk, PhD, Walter J. Paulus, MD, PhD, Victor W.M. van Hinsbergh, PhD

Source: JACC: Basic to Translational Science, Vol 4, Iss 5, Pp 575-591 (2019)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452302X1930138X; https://doaj.org/toc/2452-302X

Access URL: https://doaj.org/article/3ed290af219b4583a9eb3ca67de459dc

Regulation of microvascularization in heart failure - an endothelial cell, non-coding RNAs and exosome liaison

Authors: Rio P. Juni, Ricardo C. Abreu, Paula A. da Costa Martins

Source: Non-coding RNA Research, Vol 2, Iss 1, Pp 45-55 (2017)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S246805401630021X; https://doaj.org/toc/2468-0540

Access URL: https://doaj.org/article/13fbb3a180ee4a90b6222d51c0868aad