Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment

Authors: Hagemann, Christoffer A, Zhang, Chen, Hansen, Henrik H, Jorsal, Tina, Rigbolt, Kristoffer T G, Madsen, Martin R, Bergmann, Natasha C, Heimbürger, Sebastian M N, Falkenhahn, Mechthilde, Theis, Stefan, Breitschopf, Kristin, Holm, Stephanie, Hedegaard, Morten A, Christensen, Mikkel B, Vilsbøll, Tina, Holst, Birgitte, Vrang, Niels, Jelsing, Jacob, Knop, Filip K

Source: Journal of clinical endocrinology & metabolism. 106(2):e966-e981

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100142845480.0x000001&indx=1&recIds=ETOCvdc_100142845480.0x000001

Phosphoproteomic profiling reveals a defined genetic program for osteoblastic lineage commitment of human bone marrow—derived stromal stem cells

Authors: Barrio-Hernandez, Inigo, Jafari, Abbas, Rigbolt, Kristoffer T. G., Hallenborg, Philip, Sanchez-Quiles, Virginia, Skovrind, Ida, Akimov, Vyacheslav, Kratchmarova, Irina, Dengjel, Joern, Kassem, Moustapha

Source: Genome research. 30(1):127-137

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Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis

Authors: Tølbøl, Kirstine S., Stierstorfer, Birgit, Rippmann, Jörg F., Veidal, Sanne S., Rigbolt, Kristoffer T. G., Schönberger, Tanja, Gillum, Matthew P., Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Broermann, Andre

Source: Digestive diseases and sciences. 64(5):1238-1256

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Degradation of protein translation machinery by amino acid starvation-induced macroautophagy

Authors: Gretzmeier, Christine, Eiselein, Sven, Johnson, Gregory R., Engelke, Rudolf, Nowag, Heike, Zarei, Mostafa, Küttner, Victoria, Becker, Andrea C., Rigbolt, Kristoffer T. G., Høyer-Hansen, Maria, Andersen, Jens S., Münz, Christian, Murphy, Robert F., Dengjel, Jörn

Source: Autophagy. 13(6):1064-1075

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Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis

Authors: Ægidius, Helene M., Veidal, Sanne S., Feigh, Michael, Hallenborg, Philip, Puglia, Michele, Pers, Tune H., Vrang, Niels, Jelsing, Jacob, Kornum, Birgitte R., Blagoev, Blagoy, Rigbolt, Kristoffer T. G.

Source: Scientific reports. 10(1)

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Human translatability of the GAN diet-induced obese mouse model of non-alcoholic steatohepatitis

Authors: Hansen, Henrik H., Ægidius, Helene M., Oró, Denise, Evers, Simon S., Heebøll, Sara, Eriksen, Peter Lykke, Thomsen, Karen Louise, Bengtsson, Anja, Veidal, Sanne S., Feigh, Michel, Suppli, Malte P., Knop, Filip K., Grønbæk, Henning, Miranda, Diego, Trevaskis, James L., Vrang, Niels, Jelsing, Jacob, Rigbolt, Kristoffer T. G.

Source: BMC gastroenterology. 20(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171714286.0x000001&indx=1&recIds=ETOCvdc_100171714286.0x000001

Global transcriptome analysis of rat hypothalamic arcuate nucleus demonstrates reversal of hypothalamic gliosis following surgically and diet induced weight loss

Authors: Barkholt, Pernille, Rigbolt, Kristoffer T. G., Falkenhahn, Mechthilde, Hübschle, Thomas, Schwahn, Uwe, Fernandez-Cachon, Maria Luisa, Schmidt, Thorsten, Theis, Stefan, Hansen, Henrik H., Hay-Schmidt, Anders, Pedersen, Philip J., Vrang, Niels, Jelsing, Jacob

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132541470.0x000001&indx=1&recIds=ETOCvdc_100132541470.0x000001

Combined obeticholic acid and elafibranor treatment promotes additive liver histological improvements in a diet-induced ob/ob mouse model of biopsy-confirmed NASH

Authors: Roth, Jonathan D., Veidal, Sanne S., Fensholdt, Louise K. D., Rigbolt, Kristoffer T. G., Papazyan, Romeo, Nielsen, Jens Christian, Feigh, Michael, Vrang, Niels, Young, Mark, Jelsing, Jacob, Adorini, Luciano, Hansen, Henrik H.

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131472785.0x000001&indx=1&recIds=ETOCvdc_100131472785.0x000001

A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity.

Authors: Hagemann, Christoffer A., Legart, Christian, Møllerhøj, Mathias B., Madsen, Martin R., Hansen, Henrik H., Kønig, Merete J., Helgstrand, Frederik, Hjørne, Flemming P., Toxværd, Anders, Langhoff, Jill L., Kielgast, Urd L., Gluud, Lise L., Ægidius, Helene, Rigbolt, Kristoffer T. G., Vilsbøll, Tina, Jelsing, Jacob, Knop, Filip K.

Source: PLoS ONE; 10/19/2022, Vol. 17 Issue 10, p1-19, 19p

Subject Terms: INSULIN-like growth factor-binding proteins, NON-alcoholic fatty liver disease, BIOMARKERS, INSULIN receptors, SOMATOMEDIN C

Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells.

Authors: Halbach, Sebastian^1,2,3,4, Rigbolt, Kristoffer T. G.^2,5, Wöhrle, Franziska U.^1,2,3,4,6, Diedrich, Britta^2,5, Gretzmeier, Christine^2,5, Brummer, Tilman^1,2,3,6,7 tilman.brummer@zbsa.uni-freiburg.de, Dengjel, Jörn^2,5,6 joern.dengjel@frias.uni-freiburg.de

Source: Cell Communication & Signaling. 2013, Vol. 11 Issue 1, p1-16. 16p. 2 Diagrams, 1 Chart, 4 Graphs.

Subject Terms: *CHRONIC myeloid leukemia, *KINASE inhibitors, *PROTEIN-tyrosine kinases, *IMATINIB, *MASS spectrometry, *PROTEOMICS, *CASEIN kinase, *PHOSPHORYLATION

Identification and Metabolic Profiling of a Novel Human Gut-derived LEAP2 Fragment.

Authors: Hagemann, Christoffer A., Chen Zhang, Hansen, Henrik H., Jorsal, Tina, Rigbolt, Kristoffer T. G., Madsen, Martin R., Bergmann, Natasha C., Heimbürger, Sebastian M. N., Falkenhahn, Mechthilde, Theis, Stefan, Breitschopf, Kristin, Holm, Stephanie, Hedegaard, Morten A., Christensen, Mikkel B., Vilsbøll, Tina, Holst, Birgitte, Vrang, Niels, Jelsing, Jacob, Knop, Filip K.

Source: Journal of Clinical Endocrinology & Metabolism; Feb2021, Vol. 106 Issue 2, pe966-e981, 16p

Subject Terms: ENTEROENDOCRINE cells, GROWTH hormone releasing factor, GHRELIN receptors, MEDICAL sciences, GLUCAGON-like peptide 1, GLYCEMIC index, LIQUID chromatography-mass spectrometry

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Disease Progression and Pharmacological Intervention in a Nutrient-Deficient Rat Model of Nonalcoholic Steatohepatitis.

Authors: Tølbøl, Kirstine S., Stierstorfer, Birgit, Rippmann, Jörg F., Veidal, Sanne S., Rigbolt, Kristoffer T. G., Schönberger, Tanja, Gillum, Matthew P., Hansen, Henrik H., Vrang, Niels, Jelsing, Jacob, Feigh, Michael, Broermann, Andre

Source: Digestive Diseases & Sciences; May2019, Vol. 64 Issue 5, p1238-1256, 19p

Subject Terms: DISEASE progression, FATTY liver, DRUG efficacy, GENE expression, METABOLIC profile tests, RATS

Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals.

Authors: Suppli, Malte P.¹, Rigbolt, Kristoffer T. G.², Veidal, Sanne S.², Heebøll, Sara³, Eriksen, X. Peter Lykke³, Demant, Mia¹, Bagger, Jonatan I.¹, Nielsen, Jens Christian², Oró, Denise², Thrane, Sebastian W.², Lund, Asger¹, Strandberg, Charlotte⁴, Kønig, Merete J.⁴, Vilsbøll, Tina^1,5, Vrang, Niels², Thomsen, Karen L.³, Grønbæk, Henning³, Jelsing, Jacob², Hansen, X. Henrik H.², Knop, Filip K.^1,5,6 filip.krag.knop.01@regionh.dk

Source: American Journal of Physiology: Gastrointestinal & Liver Physiology. Apr2019, Vol. 316 Issue 4, pG462-G472. 11p.

Subject Terms: *FATTY liver, *GENE expression profiling, *LIVER histology, *EXTRACELLULAR matrix, *LIPID metabolism, *RNA sequencing

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Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways.

Authors: Kristiansen, Maria N. B., Veidal, Sanne S., Christoffersen, Christina, Jelsing, Jacob, Rigbolt, Kristoffer T. G.

Source: Lipids; Jan2019, Vol. 54 Issue 1, p109-115, 7p

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