Generation and GMP scale-up of human CAR-T cells using non-viral Sleeping Beauty transposons for B cell malignances

Authors: Diez, Begoña ^{1, 2, 3, 15}, Calviño, Cristina ^{4, 15}, Fernández-García, María ^{1, 2, 3}, Rodríguez-Márquez, Paula ⁵, Rodríguez-Díaz, Saray ⁵, Martínez-Turillas, Rebeca ^{5, 7}, Ceballos, Candela ⁸, Illarramendi, Jorge ⁸, Serrano-López, Juana ⁹, Miskey, Csaba ¹⁰, Navarro-Bailón, Almudena ^{7, 11, 12}, López-Corral, Lucía ^{7, 11, 12}, Llamas, Pilar ^{9, 13}, Redondo, Margarita ⁸, Sánchez-Guijo, Fermín ^{7, 11, 12}, Rifon, Jose ^{4, 6, 7}, Alfonso-Piérola, Ana ^{4, 6, 7}, Ivics, Zoltán ¹⁰, Inogés, Susana ^{4, 6, 7}, López-Díaz de Cerio, Ascensión ^{4, 6, 7}, Yanez, Rosa ^{1, 2, 3}, Bueren, Juan A. ^{1, 2, 3, 14, ∗}, Rodríguez-Madoz, Juan R. ^{5, 6, 7, 14, ∗∗}, Prosper, Felipe ^{4, 5, 6, 7, 14, ∗∗∗}

Source: In Molecular Therapy - Methods & Clinical Development 13 March 2025 33(1)

Molecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in multiple myeloma

Authors: Palacios-Berraquero, Maria Luisa, Rodriguez-Marquez, Paula, Calleja-Cervantes, Maria Erendira, Berastegui, Nerea, Zabaleta, Aintzane, Burgos, Leire, Alignani, Diego, San Martin-Uriz, Patxi, Vilas-Zornoza, Amaia, Rodriguez-Diaz, Saray, Inoges, Susana, Lopez-Diaz de Cerio, Ascensión, Huerga, Sofia, Tamariz, Esteban, Rifon, Jose, Alfonso-Pierola, Ana, Lasarte, Juan Jose, Paiva, Bruno, Hernaez, Mikel, Rodriguez-Otero, Paula, San-Miguel, Jesus, Ezponda, Teresa, Rodriguez-Madoz, Juan Roberto, Prosper, Felipe

Source: In Blood Advances 12 November 2024 8(21):5479-5492

Outcome of allogeneic haematopoietic cell transplantation in eosinophilic disorders: A retrospective study by the chronic malignancies working party of the EBMT

Authors: McLornan, Donal P., Gras, Luuk, Martin, Ivonne, Sirait, Tiarlan, Schroeder, Thomas, Blau, Igor Wolfgang, Kuball, Jürgen, Byrne, Jenny, Collin, Matthew, Stadler, Michael, Desmier, Déborah, Salmenniemi, Urpu, Jindra, Pavel, Mikhailova, Natalia, Lenhoff, Stig, Rifón, Jose, Robin, Marie, Rovira, Montserrat, Veelken, Hendrik, Sadowska‐Klasa, Alicja, Zecca, Marco, Hayden, Patrick J., Czerw, Tomasz, Hernández‐Boluda, Juan Carlos, Yakoub‐Agha, Ibrahim

Source: British journal of haematology. 198(1):209-213

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191749661.0x000001&indx=1&recIds=ETOCvdc_100191749661.0x000001

Engraftment after autologous hematopoietic stem cell transplantation in patients mobilized with Plerixafor: A retrospective, multicenter study of a large series of patients

Authors: Antelo, M. Luisa ^*, Altuna, Ane, Gimeno, J. José, Ferreiro, J. Javier, Amunárriz, Cristina, Mateos, J. José, Zalba, Saioa, Alkorta, Aitziber, Rifón, José, Arroyo, J. Luis, Uresandi, Amaia, Moreno, J. Antonio, Nájera, M. Josefa, Pinzón, Sergio, García, Alejandro, Vallejo, J. Carlos

Source: In Transfusion and Apheresis Science June 2021 60(3)

Treosulfan-Based Conditioning Regimen In Pediatric Hematopoietic Stem Cell Transplantation: A Retrospective Analysis on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC)

Authors: Galán, Victor, Beléndez, Cristina, Echecopar, Carlos, Estival, Pablo, Sissini, Luisa, Olivas, Raquel, Bueno, David, Molina, Blanca, Fuentes, Carolina, Regueiro, Alexandra, Benítez, Isabel, Plaza, Mercedes, Margarit, Adriana, Rifón, José, Pascual, Antonia, Palomo, Pilar, Urtasun, Andrea, Fuster, José Luis, Díaz de Heredia, Cristina, Fernández Navarro, José María, González-Vicent, Marta, Ruz, Beatriz, Pérez-Martínez, Antonio

Source: In Transplantation and Cellular Therapy November 2023 29(11):702-702

Haematopoietic stem cell transplantation in adult soft-tissue sarcoma: an analysis from the European Society for Blood and Marrow Transplantation

Authors: Heilig, Christoph E., Badoglio, Manuela, Labopin, Myriam, Fröhling, Stefan, Secondino, Simona, Heinz, Jürgen, Nicolas-Virelizier, Emmanuelle, Blaise, Didier, Korenbaum, Clément, Santoro, Armando, Verbeek, Mareike, Krüger, William, Siena, Salvatore, Passweg, Jakob R., Di Nicola, Massimo, Rifón, Jose, Dreger, Peter, Koehl, Ulrike, Chabannon, Christian, Pedrazzoli, Paolo

Source: In ESMO Open 2020 5(5)

Response to Novel Drugs before and after Allogeneic Stem Cell Transplantation in Patients with Relapsed Multiple Myeloma

Authors: López-Corral, Lucia, Caballero-Velázquez, Teresa, López-Godino, Oriana, Rosiñol, Laura, Pérez-Vicente, Sabina, Fernandez-Avilés, Francesc, Krsnik, Isabel, Morillo, Daniel, Heras, Inmaculada, Morgades, Mireia, Rifon, Jose J., Sampol, Antonia, Iniesta, Francisca, Ocio, Enrique-María, Martin, Jesús, Rovira, Montserrat, Cabero, Martín, Castilla-Llorente, Cristina, Ribera, Josep-María, Torres-Juan, Marta, Moraleda, Jose María, Martinez, Carmen, Vázquez, Alejandro, Gutierrez, Gonzalo, Caballero, Dolores, San Miguel, Jesús F., Mateos, María-Victoria, Pérez-Simón, Jose Antonio

Source: In Biology of Blood and Marrow Transplantation September 2019 25(9):1703-1712

CT-342 Prolonged Hematologic Toxicity After B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor (CAR) T-Cell Treatment: From Clinical Data to Ex-Vivo Studies at a Single Center

Authors: Palacios-Berraquero, Maria Luisa, Berrastegui, Nerea, Rodríguez-Márquez, Paula, Cervantes, Maria Erendira Calleja, Zabaleta, Aintzane, Burgos, Leire, Alignani, Diego, Martin-Uriz, Patxi San, Vilas-Zornoza, Amaia, Jordana, Lorea, Calviño, Cristina, Martín-Mallo, Angel, Rodríguez-Díaz, Saray, Inogés, Susana, de Cerio, Ascensión Lopez-Díaz, Huerga, Sofia, Rifón, Jose, Alfonso, Ana, Lasarte, Juan José, Hernaez, Mikel, Miguel, Jesús San, Rodriguez-Otero, Paula, Paiva, Bruno, Ezponda, Teresa, Rodriguez-Madoz, Juan Roberto, Prósper, Felipe

Source: Clinical lymphoma, myeloma & leukemia. 23(S1):S526-S527

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196308840.0x000001&indx=1&recIds=ETOCvdc_100196308840.0x000001

Outcomes of Unmanipulated Haploidentical Transplantation Using Post-Transplant Cyclophosphamide (PT-Cy) in Pediatric Patients With Acute Lymphoblastic Leukemia

Authors: Ruggeri, Annalisa, Galimard, Jacques-Emmanuel, Paina, Olesya, Fagioli, Franca, Tbakhi, Abdelghani, Yesilipek, Akif, Navarro, José Maria Fernandez, Faraci, Maura, Hamladji, Rose-Marie, Skorobogatova, Elena, Al-Seraihy, Amal, Sundin, Mikael, Herrera, Concepcion, Rifón, Jose, Dalissier, Arnaud, Locatelli, Franco, Rocha, Vanderson, Corbacioglu, Selim

Source: In Transplantation and Cellular Therapy May 2021 27(5):424-424

POSTER: CT-342 Prolonged Hematologic Toxicity After B-Cell Maturation Antigen (BCMA) Chimeric Antigen Receptor (CAR) T-Cell Treatment: From Clinical Data to Ex-Vivo Studies at a Single Center

Authors: Palacios-Berraquero, Maria Luisa, Berrastegui, Nerea, Rodríguez-Márquez, Paula, Cervantes, Maria Erendira Calleja, Zabaleta, Aintzane, Burgos, Leire, Alignani, Diego, Martin-Uriz, Patxi San, Vilas-Zornoza, Amaia, Jordana, Lorea, Calviño, Cristina, Martín-Mallo, Angel, Rodríguez-Díaz, Saray, Inogés, Susana, de Cerio, Ascensión Lopez-Díaz, Huerga, Sofia, Rifón, Jose, Alfonso, Ana, Lasarte, Juan José, Hernaez, Mikel, Miguel, Jesús San, Rodriguez-Otero, Paula, Paiva, Bruno, Ezponda, Teresa, Rodriguez-Madoz, Juan Roberto, Prósper, Felipe

Source: Clinical lymphoma, myeloma & leukemia. 23(S1):S230-S230

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196316955.0x000001&indx=1&recIds=ETOCvdc_100196316955.0x000001

SETBP1 overexpression is a novel leukemogenic mechanism that predicts adverse outcome in elderly patients with acute myeloid leukemia

Authors: Cristóbal, Ion, Blanco, Francisco J., Garcia-Orti, Laura, Marcotegui, Nerea, Vicente, Carmen, Rifon, José, Novo, Francisco J., Bandres, Eva, Calasanz, María J., Bernabeu, Carmelo, Odero, María D. ^*

Source: In Blood 21 January 2010 115(3):615-625

Longitudinal Transcriptomic Analysis of CAR-T Cells at Single-Cell Level Allows the Identification of Molecular Mechanisms Promoting Long-Term CAR-T Cell Persistence in MM

Authors: Rodriguez-Madoz, Juan Roberto, Jordana-Urriza, Lorea, Serrano, Guillermo, Oliver-Caldes, Aina, Calleja-Cervantes, Maria Erendira, San-Martin, Patxi, Vilas-Zornoza, Amaia, Ullate-Agote, Asier, Zabaleta, Aintzane, Alignani, Diego, Lozano, Teresa, Cabanas Perianes, Valentin, Reguera, Juan Luis, Navarro-Bailon, Almudena, Español-Rego, Marta, Pascal, Mariona, Moraleda, Jose Maria, Perez-Simon, Jose A., Mateos, Maria Victoria, Sanchez-Guijo Martin, Fermin, Urbano-Ispizua, Alvaro, Juan, Manel, Pierola, Ana Alfonso, Rifon, Jose J., Rodriguez Otero, Paula, Paiva, Bruno, Inogés, Susana, López-Díaz De Cerio, Ascensión, Lasarte, Juan J, San Miguel, Jesús, Fernández de Larrea, Carlos, Hernaez, Mikel, Prosper, Felipe

Source: In Blood 2 November 2023 142 Supplement 1:2069-2069

Optimization of a Universal Allogeneic CAR-T Cells Combining CRISPR and Transposon-Based Technologies for Treatment of Acute Myeloid Leukemia

Authors: Ceballos Bolaños, Candela, Calviño, Cristina, Pierola, Ana Alfonso, Jauregui, Patricia, Calleja-Cervantes, Maria Erendira, San-Martin, Patxi, Rodríguez Márquez, Paula, Martin Mallo, Ángel, Iglesias, Elena, Abizanda, Gloria, Rodríguez Diaz, Saray, Martínez Turrillas, Rebeca, Illarramendi Esteban, Jorge, Redondo, Ana Margarita, Viguria-Alegría, MC, Panizo, Carlos, Rifon, Jose J., Villar, Sara, Lasarte, Juan J, Inogés, Susana, López-Díaz De Cerio, Ascensión, Hernaez, Mikel, Prosper, Felipe, Rodriguez-Madoz, Juan Roberto

Source: In Blood 2 November 2023 142 Supplement 1:3457-3457

Sequential Scmultiomics of In Vivo CAR-T Cells Allows Characterization of Transcriptional Differences between Patients, and Identifies IL10 As a Potential Mechanism of Resistance to CAR-T Cells in MM

Authors: Rodriguez-Madoz, Juan Roberto, Jordana-Urriza, Lorea, Serrano, Guillermo, Oliver-Caldes, Aina, Calleja-Cervantes, Maria Erendira, San-Martin, Patxi, Vilas-Zornoza, Amaia, Ullate-Agote, Asier, Zabaleta, Aintzane, Alignani, Diego, Lozano, Teresa, Cabanas Perianes, Valentin, Reguera, Juan Luis, Navarro-Bailon, Almudena, Español-Rego, Marta, Pascal, Mariona, Moraleda, Jose Maria, Perez-Simon, Jose A., Mateos, Maria Victoria, Sanchez-Guijo Martin, Fermin, Urbano-Ispizua, Alvaro, Juan, Manel, Pierola, Ana Alfonso, Rifon, Jose J., Rodriguez Otero, Paula, Paiva, Bruno, Inogés, Susana, López-Díaz De Cerio, Ascensión, Lasarte, Juan J, San Miguel, Jesús, Fernández de Larrea, Carlos, Hernaez, Mikel, Prosper, Felipe

Source: In Blood 2 November 2023 142 Supplement 1:3433-3433

Phase I and Pharmacokinetic Study of Gemcitabine Administered at Fixed-Dose Rate, Combined with Docetaxel/Melphalan/Carboplatin, with Autologous Hematopoietic Progenitor-Cell Support, in Patients with Advanced Refractory Tumors

Authors: Nieto, Yago, Aldaz, Azucena, Rifón, José, Pérez-Calvo, Javier, Zafra, Ana, Zufia, Laura, Viúdez, Antonio, Viteri, Santiago, Aramendía, José Manuel, Aristu, Javier, Centeno, Carlos, Moreno, Marta, Sayar, Onintza, Hernández, Milagros

Source: In Biology of Blood and Marrow Transplantation 2007 13(11):1324-1337

OA-11 Utility of 18FDG-PET/CT for risk prediction in relapsed/refractory multiple myeloma patients undergoing CAR-T cell therapy: analysis of baseline and early assessment scans after one and three months

Authors: Tamariz-Amador, Luis-Esteban, Alfonso-Pierola, Ana, Huerga-Dominguez, Sofia, Panizo-Inoges, Maria, Palacios-Berraquero, Maria-Luisa, Villar, Sara, Marcos-Jubilar, Maria, Betech-Antar, Victoria, Valencia-Espinoza, Evelyn, Rifon, Jose, Prosper, Felipe, San-Miguel, Jesús, Garcia-Velloso, Maria-Jose, Rodriguez-Otero, Paula

Source: In Clinical Lymphoma, Myeloma and Leukemia September 2023 23 Supplement 2:S7-S7

Thrombopenic purpura induced by a monoclonal antibody directed to a 35-kilodalton surface protein (p35) expressed on murine platelets and endothelial cells

Authors: Rodrı́guez-Calvillo, Mercedes ^*, Gabari, Izaskun ^*, Duarte, Marina, Mazzolini, Guillermo, Rifón, José, Rocha, Eduardo, Prieto, Jesús, Melero, Ignacio ^*

Source: In Experimental Hematology 2001 29(5):589-595

Measurement of Prethrombotic Markers in the Assessment of Acquired Hypercoagulable States

Authors: López, Yolanda ¹, Paloma, Maria José ², Rifón, José ¹, Cuesta, Braulia ¹, Páramo, José A. ^{1, *}

Source: In Thrombosis Research 1999 93(2):71-78

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