Canadian Content in the Pages of Drug Metabolism and Disposition: A Comprehensive Historical Analysis

Authors: Riddick, David S. ^*

Source: In Drug Metabolism and Disposition January 2024 52(1):1-18

Fifty Years of Aryl Hydrocarbon Receptor Research as Reflected in the Pages of Drug Metabolism and Disposition

Authors: Riddick, David S. ^*

Source: In Drug Metabolism and Disposition June 2023 51(6):657-671

Role of Glucocorticoid Receptor and Pregnane X Receptor in Dexamethasone Induction of Rat Hepatic Aryl Hydrocarbon Receptor Nuclear Translocator and NADPH-Cytochrome P450 Oxidoreductase

Authors: Hunter, Sarah R. ¹, Vonk, Alex ¹, Grey, Anne K. Mullen, Riddick, David S. ^*

Source: In Drug Metabolism and Disposition February 2017 45(2):118-129

The Role of Cytochrome P450–Dependent Metabolism in the Regulation of Mouse Hepatic Growth Hormone Signaling Components and Target Genes by 3-Methylcholanthrene

Authors: Lee, Chunja, Ding, Xinxin, Riddick, David S. ^*

Source: In Drug Metabolism and Disposition February 2013 41(2):457-465

Induction of Multidrug Resistance Transporter ABCG2 by Prolactin in Human Breast Cancer Cells

Authors: Wu, Alex Man Lai, Dalvi, Pooja, Lu, Xiaoli, Yang, Mingdong, Riddick, David S., Matthews, Jason, Clevenger, Charles V., Ross, Douglas D., Harper, Patricia A., Ito, Shinya ^*

Source: In Molecular Pharmacology February 2013 83(2):377-388

NADPH–Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology

Authors: Riddick, David S ^{1, *}, Ding, Xinxin ², Wolf, C. Roland ³, Porter, Todd D ¹, Pandey, Amit V ⁵, Zhang, Qing-Yu ², Gu, Jun ², Finn, Robert D ³, Ronseaux, Sebastien ^{3, 1}, McLaughlin, Lesley A ³, Henderson, Colin J ³, Zou, Ling ⁴, Flück, Christa E ⁵

Source: In Drug Metabolism and Disposition January 2013 41(1):12-23

Mechanisms of NADPH – cytochrome P450 oxidoreductase induction by dexamethasone in the H4IIE rat hepatoma cell line.

Authors: Riddick, David S.¹ david.riddick@utoronto.ca, Mullen Grey, Anne K.¹

Source: Canadian Journal of Physiology & Pharmacology. 2020, Vol. 98 Issue 5, p267-274. 8p.

Subject Terms: *CYTOCHROME P-450, *MICROSOMES, *GLUCOCORTICOIDS, *CELL lines, *NICOTINAMIDE adenine dinucleotide phosphate, *PREGNANE X receptor, *CYTOCHROME c, *RATS

The Aryl Hydrocarbon Receptor Pathway and the Response to 3-Methylcholanthrene Are Altered in the Liver of Adrenalectomized Rats

Authors: Grey, Anne K. Mullen, Riddick, David S. ^*

Source: In Drug Metabolism and Disposition January 2011 39(1):83-91

Glucocorticoid and adrenalectomy effects on the rat aryl hydrocarbon receptor pathway depend on the dosing regimen and post-surgical time

Authors: Mullen Grey, Anne K., Riddick, David S.

Source: In Chemico-Biological Interactions 2009 182(2):148-158

Cytochrome P450 2C11 5′-Flanking Region and Promoter Mediate in Vivo Suppression by 3-Methylcholanthrene

Authors: Sawaya, Rana M., Riddick, David S. ^*

Source: In Drug Metabolism and Disposition September 2008 36(9):1803-1811

Regulation of Aryl Hydrocarbon Receptor Expression and Function by Glucocorticoids in Mouse Hepatoma Cells

Authors: Bielefeld, Kirsten A., Lee, Chunja, Riddick, David S. ^*

Source: In Drug Metabolism and Disposition March 2008 36(3):543-551

Cytochrome P450 2C11 5′-flanking region and promoter: Regulation by aromatic hydrocarbons in vitro

Authors: Sawaya, Rana M., Riddick, David S.

Source: In Toxicology 2008 248(2):104-112

Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines.

Authors: Utgikar, Rucha¹, Riddick, David S.¹

Source: Canadian Journal of Physiology & Pharmacology. 2017, Vol. 95 Issue 6, p768-771. 4p.

Subject Terms: *DOWNREGULATION, *CYTOCHROME P-450, *CELLULAR control mechanisms, *CELL lines, *PHYSIOLOGY

Suppression of Hepatic CYP3A4 Expression and Activity by 3-Methylcholanthrene in Humanized PXR-CAR-CYP3A4/3A7 Mice

Authors: Crosby, Michael, Riddick, David S. ^*

Source: In Drug Metabolism and Disposition July 2019 47(3):279-282

Aromatic Hydrocarbon Receptor Expression and Function in Liver of Hypophysectomized Male Rats

Authors: Timsit, Yoav E., Chia, Frank Shih-Chang, Bhathena, Anahita, Riddick, David S.

Source: In Toxicology and Applied Pharmacology 2002 185(2):136-145

Interference with Growth Hormone Stimulation of Hepatic Cytochrome P4502C11 Expression in Hypophysectomized Male Rats by 3-Methylcholanthrene

Authors: Timsit, Yoav E., Riddick, David S.

Source: In Toxicology and Applied Pharmacology 1 March 2000 163(2):105-114

Transcriptional suppression of cytochrome P450 2C11 gene expression by 3-methylcholanthrene

Authors: Lee, Chunja, Riddick, David S ^*

Source: In Biochemical Pharmacology 2000 59(11):1417-1423

The 2001 Veylien Henderson Award of the Society of Toxicology of Canada. Positive and negative transcriptional regulation of cytochromes P450 by polycyclic aromatic hydrocarbons.

Authors: Riddick, David S., Lee, Chunja, Bhathena, Anahita, Timsit, Yoav E.

Source: Canadian Journal of Physiology & Pharmacology. Jan2003, Vol. 81 Issue 1, p59. 19p. 4 Diagrams, 1 Chart, 2 Graphs.

Subject Terms: *HYDROCARBONS, *CYTOCHROME P-450, *SOMATOTROPIN, *CYTOCHROMES

Pharmacokinetics: Overview

Authors: Riddick, David S.

Source: In Reference Module in Biomedical Research 2015

Downregulation of Mouse Hepatic CYP3A Protein by 3-Methylcholanthrene Does Not Require Cytochrome P450-Dependent Metabolism

Authors: Lee, Chunja, Ding, Xinxin, Riddick, David S. ^*

Source: In Drug Metabolism and Disposition October 2013 41(10):1782-1786