A human milk oligosaccharide prevents intestinal inflammation in adulthood via modulating gut microbial metabolism

Authors: Kasey M. Schalich, Matthew A. Buendia, Harpreet Kaur, Yash A. Choksi, M. Kay Washington, Gabriela S. Codreanu, Stacy D. Sherrod, John A. McLean, Richard M. Peek, Jr., Sari A. Acra, Steven D. Townsend, Fang Yan

Source: mBio, Vol 15, Iss 4 (2024)

Subject Terms: 2′-fucosyllactose, Bifidobacterium longum subsp. infantis, human milk oligosaccharide, inflammatory bowel diseases, intestinal barrier, pantothenate, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/b1067dced790480e8612a3e92377e026

Gastric coinfection with thiopeptide-positive Cutibacterium acnes decreases FOXM1 and pro-inflammatory biomarker expression in a murine model of Helicobacter pylori-induced gastric cancer

Authors: Courtney Lunger, Zeli Shen, Hilda Holcombe, Anthony J. Mannion, JoAnn Dzink-Fox, Susanna Kurnick, Yan Feng, Sureshkumar Muthupalani, Sebastian E. Carrasco, Keith T. Wilson, Richard M. Peek, M. Blanca Piazuelo, Douglas R. Morgan, Amanda L. Armijo, Melissa Mammoliti, Timothy C. Wang, James G. Fox

Source: Microbiology Spectrum, Vol 12, Iss 1 (2024)

Subject Terms: Helicobacter pylori, non-H. pylori gastric bacteria, Cutibacterium acnes, thiopeptide, gnotobiotic mouse model, mouse model of H. pylori-induced gastric cancer, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/0cc4e0cdd03c4002a30d01f014dbcd22

Identification of a functional peptide of a probiotic bacterium-derived protein for the sustained effect on preventing colitis

Authors: Harpreet Kaur, Syed Azmal Ali, Sarah P. Short, Christopher S. Williams, Jeremy A. Goettel, M. Kay Washington, Richard M. Peek, Sari A. Acra, Fang Yan

Source: Gut Microbes, Vol 15, Iss 2 (2023)

Subject Terms: Histone methyltransferase, intestinal epithelial cell, p40, Setd1β, TGFβ, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/fbd498869d1e4dc9a38573f75067729d

Targeting hypoxia-inducible factor-1 alpha suppresses Helicobacter pylori-induced gastric injury via attenuation of both cag-mediated microbial virulence and proinflammatory host responses

Authors: Jennifer M. Noto, M. Blanca Piazuelo, Judith Romero-Gallo, Alberto G. Delgado, Giovanni Suarez, Konstantina Akritidou, Miguel Girod Hoffman, Juan Carlos Roa, Cormac T. Taylor, Richard M. Peek

Source: Gut Microbes, Vol 15, Iss 2 (2023)

Subject Terms: Helicobacter pylori, gastric inflammation, gastric cancer, hypoxia-inducible factor-1 alpha (HIF-1α), dimethyloxalylglycine (DMOG), prolyl hydroxylase (PHD), Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/5ca1554c76e54c8382886b3806ff21b3

Helicobacter pylori actively suppresses innate immune nucleic acid receptors

Authors: Samuel D.R. Dooyema, Jennifer M. Noto, Lydia E. Wroblewski, M. Blanca Piazuelo, Uma Krishna, Giovanni Suarez, Judith Romero-Gallo, Alberto G. Delgado, Richard M. Peek

Source: Gut Microbes, Vol 14, Iss 1 (2022)

Subject Terms: Helicobacter pylori, gastric cancer, TLR9, STING, RIG-I, TRIM30, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/f93259ca2dbb4a9897baa17e0061a47a

Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβSummary

Authors: Yilin Deng, Oliver G. McDonald, Anna L. Means, Richard M. Peek, Jr., M. Kay Washington, Sari A. Acra, D. Brent Polk, Fang Yan

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1327-1345 (2021)

Subject Terms: Histone Methyltransferase, Intestinal Epithelial Cell, Probiotic Function Factor, Regulatory T Cell, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X21000102; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/c9d8505ae2364be6b0977cbd4b2e1b5b

Iron deficiency linked to altered bile acid metabolism promotes Helicobacter pylori–induced inflammation–driven gastric carcinogenesis

Authors: Jennifer M. Noto, M. Blanca Piazuelo, Shailja C. Shah, Judith Romero-Gallo, Jessica L. Hart, Chao Di, James D. Carmichael, Alberto G. Delgado, Alese E. Halvorson, Robert A. Greevy, Lydia E. Wroblewski, Ayushi Sharma, Annabelle B. Newton, Margaret M. Allaman, Keith T. Wilson, M. Kay Washington, M. Wade Calcutt, Kevin L. Schey, Bethany P. Cummings, Charles R. Flynn, Joseph P. Zackular, Richard M. Peek Jr.

Source: The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)

Subject Terms: Gastroenterology, Infectious disease, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/7d198f5f9fa7400583ab84388b9c0680

Gastric Non-Helicobacter pylori Urease-Positive Staphylococcus epidermidis and Streptococcus salivarius Isolated from Humans Have Contrasting Effects on H. pylori-Associated Gastric Pathology and Host Immune Responses in a Murine Model of Gastric Cancer

Authors: Zeli Shen, JoAnn Dzink-Fox, Yan Feng, Sureshkumar Muthupalani, Anthony J. Mannion, Alexander Sheh, Mark T. Whary, Hilda R. Holcombe, Blanca M. Piazuelo, Luis E. Bravo, Christine Josenhans, Sebastian Suerbaum, Keith T. Wilson, Richard M. Peek, Timothy C. Wang, James G. Fox

Source: mSphere, Vol 7, Iss 1 (2022)

Subject Terms: H. pylori, microbiome, S. epidermidis, S. salivarius, INS-GAS mice, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/9e55ff19818544809735685cec27b446

Geospatial analyses identify regional hot spots of diffuse gastric cancer in rural Central America

Authors: Ricardo L. Dominguez, Charlotte B. Cherry, Dago Estevez-Ordonez, Robertino Mera, Veronica Escamilla, Michael Pawlita, Tim Waterboer, Keith T. Wilson, Richard M. Peek, Gloria Tavera, Scott M. Williams, Margaret L. Gulley, Michael Emch, Douglas R. Morgan

Source: BMC Cancer, Vol 19, Iss 1, Pp 1-8 (2019)

Subject Terms: Gastric cancer, Diffuse gastric cancer, Germline mutations, H. pylori, Central America, CA-4, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-019-5726-x; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/6e204d4cf95e44dbb7ca27e58e233ba1

Upper Endoscopy up to 3 Years Prior to a Diagnosis of Gastric Cancer Is Associated With Lower Stage of Disease in a USA Multiethnic Urban Population, a Retrospective Study

Authors: Shailja C. Shah, Chiaki Nakata, Alexandros D. Polydorides, Richard M. Peek, Steven H. Itzkowitz

Source: Journal of Preventive Medicine and Public Health, Vol 52, Iss 3, Pp 179-187 (2019)

Subject Terms: Early diagnosis, Gastrointestinal neoplasm, Intestinal metaplasia, Atrophic gastritis, Race factors, Medicine, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.jpmph.org/upload/pdf/jpmph-52-3-179.pdf; https://doaj.org/toc/1975-8375; https://doaj.org/toc/2233-4521

Access URL: https://doaj.org/article/c3fce6ec30384d70a8a2ed73ea37a4e3

Identification of New Helicobacter pylori Subpopulations in Native Americans and Mestizos From Peru

Authors: Andrés Julián Gutiérrez-Escobar, Billie Velapatiño, Victor Borda, Charles S. Rabkin, Eduardo Tarazona-Santos, Lilia Cabrera, Jaime Cok, Catherine C. Hooper, Helena Jahuira-Arias, Phabiola Herrera, Mehwish Noureen, Difei Wang, Judith Romero-Gallo, Bao Tran, Richard M. Peek, Douglas E. Berg, Robert H. Gilman, M. Constanza Camargo

Source: Frontiers in Microbiology, Vol 11 (2020)

Subject Terms: Amerindians, ancestry, indigenous, hspAmerind, mestizo, Peru, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2020.601839/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/b6b76ee877c3446495f39bc0a0397410

Cancer Control in Low- and Middle-Income Countries: Is It Time to Consider Screening?

Authors: Shailja C. Shah, Violet Kayamba, Richard M. Peek Jr, Douglas Heimburger

Source: Journal of Global Oncology, Vol 5, Pp 1-8 (2019)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2378-9506

Access URL: https://doaj.org/article/3df6ee29a18243c5b66cc8cca8ab3d10

RNF43: A Biomarker With Potential Ramifications for Therapeutic Intervention in Gastric Cancer

Authors: Jennifer M. Noto, PhD, Richard M. Peek, Jr, MD

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1202-1203 (2021)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X20301983; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/d971009f9b8d4d0bae0a2b211414f462

Modification of the Gastric Mucosal Microbiota by a Strain-Specific Helicobacter pylori Oncoprotein and Carcinogenic Histologic Phenotype

Authors: Jennifer M. Noto, Joseph P. Zackular, Matthew G. Varga, Alberto Delgado, Judith Romero-Gallo, Matthew B. Scholz, M. Blanca Piazuelo, Eric P. Skaar, Richard M. Peek

Source: mBio, Vol 10, Iss 3 (2019)

Subject Terms: CagA, Helicobacter pylori, gastric cancer, gastric microbiota, iron deficiency, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/4e1d7e064e0343d7a2ef53ea353bd1c7

Association of Combined Sero-Positivity to Helicobacter pylori and Streptococcus gallolyticus with Risk of Colorectal Cancer

Authors: Meira Epplein, Loïc Le Marchand, Timothy L. Cover, Mingyang Song, William J. Blot, Richard M. Peek, Lauren R. Teras, Kala Visvanathan, Yu Chen, Howard D. Sesso, Anne Zeleniuch-Jacquotte, Sonja I. Berndt, John D. Potter, Marc D. Ryser, Christopher A. Haiman, Sylvia Wassertheil-Smoller, Lesley F. Tinker, Tim Waterboer, Julia Butt

Source: Microorganisms, Vol 8, Iss 11, p 1698 (2020)

Subject Terms: Helicobacter pylori, Streptococcus gallolyticus, colorectal cancer, sero-positivity, antibodies, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/8/11/1698; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/9d4b3cffad7a446eb4ea3dd42bc3b151

LATS Dance: Molecular Choreography Between a Chronic Human Pathogen and Its Host

Authors: Giovanni Suarez, PhD, Richard M. Peek, Jr., MD

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 2, Pp 335-336 (2020)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X19301250; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/41315d7b42984d28a418eff3f2d32e4e

Helicobacter pylori genetic diversification in the Mongolian gerbil model

Authors: Amber C. Beckett, John T. Loh, Abha Chopra, Shay Leary, Aung Soe Lin, Wyatt J. McDonnell, Beverly R.E.A. Dixon, Jennifer M. Noto, Dawn A. Israel, Richard M. Peek Jr, Simon Mallal, Holly M. Scott Algood, Timothy L. Cover

Source: PeerJ, Vol 6, p e4803 (2018)

Subject Terms: Helicobacter pylori, Quasispecies, Mutation, Genetic diversity, Evolution, Animal models, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/4803.pdf; https://peerj.com/articles/4803/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/7e2557821c3244d6b83bd4644d72624f

Not All Mice Are the Same: Standardization of Animal Research Data Presentation

Authors: M. Bishr Omary, David E. Cohen, Emad M. El-Omar, Rajiv Jalan, Malcolm J. Low, Michael H. Nathanson, Richard M. Peek, Jr., Jerrold R. Turner

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 4, Pp 391-393 (2016)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X16300303; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/f31acfa7934c401aaf44ed069a4af868

Helicobacter pylori Type IV Secretion System and Its Adhesin Subunit, CagL, Mediate Potent Inflammatory Responses in Primary Human Endothelial Cells

Authors: Mona Tafreshi, Jyeswei Guan, Rebecca J. Gorrell, Nicole Chew, Yue Xin, Virginie Deswaerte, Manfred Rohde, Roger J. Daly, Richard M. Peek, Brendan J. Jenkins, Elizabeth M. Davies, Terry Kwok

Source: Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)

Subject Terms: Helicobacter, type IV secretion, interleukin-8, endothelial cells, inflammation, CagL, Microbiology, QR1-502

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fcimb.2018.00022/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/b1a097d42b064ad4bc1909c04fb46664

The Anti-Proliferative and Anti-Invasive Effect of Leaf Extracts of Blueberry Plants Treated with Methyl Jasmonate on Human Gastric Cancer In Vitro Is Related to Their Antioxidant Properties

Authors: Alejandra Ribera-Fonseca, Danae Jiménez, Pamela Leal, Ismael Riquelme, Juan Carlos Roa, Miren Alberdi, Richard M. Peek, Marjorie Reyes-Díaz

Source: Antioxidants, Vol 9, Iss 1, p 45 (2020)

Subject Terms: gastric cancer, methyl jasmonate, antioxidants, anticarcinogenic, blueberry, phenols, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/9/1/45; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/4b942e7b32244dde9098b3da9e209ab2