Acid sphingomyelinase inhibition induces cerebral angiogenesis post-ischemia/reperfusion in an oxidative stress-dependent way and promotes endothelial survival by regulating mitochondrial metabolism

Authors: Ayan Mohamud Yusuf, Mina Borbor, Tanja Hussner, Carolin Weghs, Britta Kaltwasser, Matthias Pillath-Eilers, Bernd Walkenfort, Richard Kolesnick, Erich Gulbins, Dirk M. Hermann, Ulf Brockmeier

Source: Cell Death and Disease, Vol 15, Iss 9, Pp 1-14 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/bb96a3a7cca44e52960359d37b31a205

Radiation-induced gastrointestinal (GI) syndrome as a function of age

Authors: Hongyan Li, Herman C. Kucharavy, Carla Hajj, Liyang Zhao, Guoqiang Hua, Ryan Glass, Phillip B. Paty, Zvi Fuks, Richard Kolesnick, Karen Hubbard, Adriana Haimovitz-Friedman

Source: Cell Death Discovery, Vol 9, Iss 1, Pp 1-7 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/0af0995b6bde418190a8d6665f7d9f00

Acid Sphingomyelinase-Ceramide Induced Vascular Injury Determines Colorectal Cancer Stem Cell Fate

Authors: Christy Li, Stefan Klingler, Sahra Bodo, Jin Cheng, Yan Pan, Mohammed Adileh, Maria Laura Martin, John Fuller, Regina Feldman, Adam Michel, Zhigang Zhang, Zvi Fuks, Richard Kolesnick

Source: Cellular Physiology and Biochemistry, Vol 56, Iss 4, Pp 436-448 (2022)

Subject Terms: Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.cellphysiolbiochem.com/Articles/000562/; https://doaj.org/toc/1015-8987

Access URL: https://doaj.org/article/016b9a1235f543ed8b0a9269c1f64cec

Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury

Authors: Irina Petrache, Elisabet Pujadas, Aditya Ganju, Karina A. Serban, Alexander Borowiec, Beatrice Babbs, Irina A. Bronova, Nicholas Egersdorf, Patrick S. Hume, Khushboo Goel, William J. Janssen, Evgeny V. Berdyshev, Carlos Cordon-Cardo, Richard Kolesnick

Source: JCI Insight, Vol 8, Iss 10 (2023)

Subject Terms: COVID-19, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/941d1f0f2b0b4a3796435b73218fab88

Enhancement of Soft Tissue Sarcoma Response to Gemcitabine through Timed Administration of a Short-Acting Anti-Angiogenic Agent

Authors: Jin Cheng, John Fuller, Regina Feldman, William Tap, Takashi Owa, Zvi Fuks, Richard Kolesnick

Source: Cellular Physiology and Biochemistry, Vol 54, Iss 4, Pp 707-718 (2020)

Subject Terms: Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://www.cellphysiolbiochem.com/Articles/000250/; https://doaj.org/toc/1015-8987

Access URL: https://doaj.org/article/628ad87240724b2694ce3f30b3a775b1

Disruption of the crypt niche promotes outgrowth of mutated colorectal tumor stem cells

Authors: Stefan Klingler, Kuo-Shun Hsu, Guoqiang Hua, Maria Laura Martin, Mohammad Adileh, Timour Baslan, Zhigang Zhang, Philip B. Paty, Zvi Fuks, Anthony M.C. Brown, Richard Kolesnick

Source: JCI Insight, Vol 7, Iss 5 (2022)

Subject Terms: Oncology, Stem cells, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/9ef3f2bee094401588a41ba8a913fa23

Correction: Radiation-induced gastrointestinal (GI) syndrome as a function of age

Authors: Hongyan Li, Herman C. Kucharavy, Carla Hajj, Liyang Zhao, Guoqiang Hua, Ryan Glass, Phillip B. Paty, Zvi Fuks, Richard Kolesnick, Karen Hubbard, Adriana Haimovitz-Friedman

Source: Cell Death Discovery, Vol 9, Iss 1, Pp 1-1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/abc9c00ff9e24876a08e7df9fc13cef9

Anti-ceramide single-chain variable fragment mitigates radiation GI syndrome mortality independent of DNA repair

Authors: Jimmy A. Rotolo, Chii Shyang Fong, Sahra Bodo, Prashanth K.B. Nagesh, John Fuller, Thivashnee Sharma, Alessandra Piersigilli, Zhigang Zhang, Zvi Fuks, Vijay K. Singh, Richard Kolesnick

Source: JCI Insight, Vol 6, Iss 8 (2021)

Subject Terms: Stem cells, Vascular biology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/76b420606de142dd89228218364193f3

Correction: Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors.

Authors: Xinzhu Deng, David Michaelson, Jason Tchieu, Jin Cheng, Diana Rothenstein, Regina Feldman, Sang-gyu Lee, John Fuller, Adriana Haimovitz-Friedman, Lorenz Studer, Simon Powell, Zvi Fuks, E Jane Albert Hubbard, Richard Kolesnick

Source: PLoS ONE, Vol 11, Iss 1, p e0141673 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4723052?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/97a50e8d002e4651ab01f6568f45bbd3

Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors.

Authors: Xinzhu Deng, David Michaelson, Jason Tchieu, Jin Cheng, Diana Rothenstein, Regina Feldman, Sang-gyu Lee, John Fuller, Adriana Haimovitz-Friedman, Lorenz Studer, Simon Powell, Zvi Fuks, E Jane Albert Hubbard, Richard Kolesnick

Source: PLoS ONE, Vol 10, Iss 6, p e0127862 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4485896?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/382b1d3647984131982f913d81a6604e

Correction: Mitochondrial Ceramide-Rich Macrodomains Functionalize Bax upon Irradiation.

Authors: Hyunmi Lee, Jimmy A Rotolo, Judith Mesicek, Tuula Penate-Medina, Andreas Rimner, Wen-Chieh Liao, Xianglei Yin, Govind Ragupathi, Desiree Ehleiter, Erich Gulbins, Dayong Zhai, John C Reed, Adriana Haimovitz-Friedman, Zvi Fuks, Richard Kolesnick

Source: PLoS ONE, Vol 10, Iss 12, p e0146210 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4696794?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dda7ebbc7ac843c88750940983b5f994

Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure.

Authors: Branka Stancevic, Nira Varda-Bloom, Jin Cheng, John D Fuller, Jimmy A Rotolo, Mónica García-Barros, Regina Feldman, Shyam Rao, Ralph R Weichselbaum, Dror Harats, Adriana Haimovitz-Friedman, Zvi Fuks, Michel Sadelain, Richard Kolesnick

Source: PLoS ONE, Vol 8, Iss 8, p e69025 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23936314/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/385d5a0a20444620b152eb931564bc92

Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation.

Authors: Hyunmi Lee, Jimmy A Rotolo, Judith Mesicek, Tuula Penate-Medina, Andreas Rimner, Wen-Chieh Liao, Xianglei Yin, Govind Ragupathi, Desiree Ehleiter, Erich Gulbins, Dayong Zhai, John C Reed, Adriana Haimovitz-Friedman, Zvi Fuks, Richard Kolesnick

Source: PLoS ONE, Vol 6, Iss 6, p e19783 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3113798?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4cc946576a3b43da8e0f310b42c9ba73

Endothelial membrane remodeling is obligate for anti-angiogenic radiosensitization during tumor radiosurgery.

Authors: Jean-Philip Truman, Mónica García-Barros, Matthew Kaag, Dolores Hambardzumyan, Branka Stancevic, Michael Chan, Zvi Fuks, Richard Kolesnick, Adriana Haimovitz-Friedman

Source: PLoS ONE, Vol 5, Iss 9 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2947950; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ce11c33c499e45e9a50276a6e97fe7a0

Endothelial membrane remodeling is obligate for anti-angiogenic radiosensitization during tumor radiosurgery.

Authors: Jean-Philip Truman, Mónica García-Barros, Matthew Kaag, Dolores Hambardzumyan, Branka Stancevic, Michael Chan, Zvi Fuks, Richard Kolesnick, Adriana Haimovitz-Friedman

Source: PLoS ONE, Vol 5, Iss 8, p e12310 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2924400?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f9dc530fbeba496fa032fdabde1255c4