Report on the 23rd FEBS Young Scientists' Forum 2024

Authors: Riccardo Miggiano, Luigi Ippolito, Chiara Paganini, Alessio Paone, Francesca Tonelli, Sonia Trojan, Irene Díaz‐Moreno

Source: FEBS Open Bio, Vol 14, Iss 12, Pp 1934-1939 (2024)

Subject Terms: FEBS, meeting report, YSF, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2211-5463

Access URL: https://doaj.org/article/aad7a46daf774a8084098fdc427780ca

ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism

Authors: Giulia Dematteis, Laura Tapella, Claudio Casali, Maria Talmon, Elisa Tonelli, Simone Reano, Adele Ariotti, Emanuela Pessolano, Justyna Malecka, Gabriela Chrostek, Gabrielė Kulkovienė, Danielius Umbrasas, Carla Distasi, Mariagrazia Grilli, Graham Ladds, Nicoletta Filigheddu, Luigia Grazia Fresu, Katsuhiko Mikoshiba, Carlos Matute, Paula Ramos-Gonzalez, Aiste Jekabsone, Tito Calì, Marisa Brini, Marco Biggiogera, Fabio Cavaliere, Riccardo Miggiano, Armando A. Genazzani, Dmitry Lim

Source: Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/ae705db1dd34467e896aab04041a0d1f

Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues

Authors: Arianna Esposito Verza, Riccardo Miggiano, Fabrizio Lombardo, Carmine Fiorillo, Bruno Arcà, Beatrice Purghé, Erika Del Grosso, Ubaldina Galli, Menico Rizzi, Franca Rossi

Source: Current Research in Structural Biology, Vol 4, Iss , Pp 246-255 (2022)

Subject Terms: Cytosolic sulfotransferase, SULT, Mosquito, Crystal structure, Differential mRNA expression, Reproductive system, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2665928X22000228; https://doaj.org/toc/2665-928X

Access URL: https://doaj.org/article/612717f95e7641e588e678c52fe124bc

The integration of AlphaFold-predicted and crystal structures of human trans-3-hydroxy-l-proline dehydratase reveals a regulatory catalytic mechanism

Authors: Eugenio Ferrario, Riccardo Miggiano, Menico Rizzi, Davide M. Ferraris

Source: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3874-3883 (2022)

Subject Terms: Computational protein structure prediction, Computational oligomerization prediction, AlphaFold, Crystal structure, Trans-3-Hydroxy-l-proline, Dehydratase, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037022003075; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/302d3f62093c44ab8273b5bf3ff3193f

First thermostable CLIP-tag by rational design applied to an archaeal O6-alkyl-guanine-DNA-alkyl-transferase

Authors: Rosa Merlo, Rosanna Mattossovich, Marianna Genta, Anna Valenti, Giovanni Di Mauro, Alberto Minassi, Riccardo Miggiano, Giuseppe Perugino

Source: Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5275-5286 (2022)

Subject Terms: Protein-tag, Protein labelling, Orthogonal substrate specificity, Thermozymes, Protein engineering, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037022004226; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/d262cf436f48474d9b6504a6328de084

The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate

Authors: Rosa Merlo, Diego Caprioglio, Michele Cillo, Anna Valenti, Rosanna Mattossovich, Castrese Morrone, Alberto Massarotti, Franca Rossi, Riccardo Miggiano, Antonio Leonardi, Alberto Minassi, Giuseppe Perugino

Source: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 85-97 (2021)

Subject Terms: protein-tag, protein labelling, enzymatic reaction, click chemistry, biotechnology, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1475-6366; https://doaj.org/toc/1475-6374

Access URL: https://doaj.org/article/e8b45e7cf72a457c9492eda4510feb35

Engineering, Characterization, and Biological Evaluation of an Antibody Targeting the HGF Receptor

Authors: Claudia Desole, Simona Gallo, Annapia Vitacolonna, Elisa Vigna, Cristina Basilico, Francesca Montarolo, Francesca Zuppini, Elena Casanova, Riccardo Miggiano, Davide Maria Ferraris, Antonio Bertolotto, Paolo Maria Comoglio, Tiziana Crepaldi

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: HGF, MET, PSI domains, antibody engineering, regenerative medicine, anti-cancer therapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.775151/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/7fa4ce6435b044b2be29090950ec838a

Toll-like receptor 4-mediated inflammation triggered by extracellular IFI16 is enhanced by lipopolysaccharide binding.

Authors: Andrea Iannucci, Valeria Caneparo, Stefano Raviola, Isacco Debernardi, Donato Colangelo, Riccardo Miggiano, Gloria Griffante, Santo Landolfo, Marisa Gariglio, Marco De Andrea

Source: PLoS Pathogens, Vol 16, Iss 9, p e1008811 (2020)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/2da90dc35e4a4ff49a931036a2cb8a8b

Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis

Authors: Stefano Donini, Davide M. Ferraris, Riccardo Miggiano, Alberto Massarotti, Menico Rizzi

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0ec3c764078249c39a6a0b3f9b936c3b

The Synthesis of Kynurenic Acid in Mammals: An Updated Kynurenine Aminotransferase Structural KATalogue

Authors: Franca Rossi, Riccardo Miggiano, Davide M. Ferraris, Menico Rizzi

Source: Frontiers in Molecular Biosciences, Vol 6 (2019)

Subject Terms: kynurenine pathway, kynurenic acid, kynurenine aminotransferase, PLP enzyme, crystal structure, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmolb.2019.00007/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/db429b5a976b439e8fe653fe03649d70

Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment

Authors: Riccardo Miggiano, Menico Rizzi, Davide M. Ferraris

Source: Pathogens, Vol 9, Iss 5, p 385 (2020)

Subject Terms: M. tuberculosis, tuberculosis, host-pathogen interactions, immune response, antitubercular drug discovery, antitubercular treatments, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/9/5/385; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/fd752cdd8dd64437aaee287afa61b593

Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair

Authors: Riccardo Miggiano, Castrese Morrone, Franca Rossi, Menico Rizzi

Source: Molecules, Vol 25, Iss 5, p 1205 (2020)

Subject Terms: mycobacterium tuberculosis, nucleotide synthesis, dna replication, dna repair, antitubercular drugs, novel drug targets, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/5/1205; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/b48fd33ca7c841c2a3f9d79e15bf24e3

Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis.

Authors: Stefano Donini, Silvia Garavaglia, Davide M Ferraris, Riccardo Miggiano, Shigetarou Mori, Keigo Shibayama, Menico Rizzi

Source: PLoS ONE, Vol 12, Iss 4, p e0175815 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5395218?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8abc1cd04cd64b2fb23523b3312f2231

Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets

Authors: Davide M. Ferraris, Riccardo Miggiano, Franca Rossi, Menico Rizzi

Source: Pathogens, Vol 7, Iss 1, p 17 (2018)

Subject Terms: Mycobacterium tuberculosis, tuberculosis, antitubercular drugs, target identification, drug discovery, Medicine

File Description: electronic resource

Relation: http://www.mdpi.com/2076-0817/7/1/17; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/a78abad3bb2e46ad9b62f73652d62865