Shared Molecular Pathways in Glaucoma and Other Neurodegenerative Diseases: Insights from RNA-Seq Analysis and miRNA Regulation for Promising Therapeutic Avenues.

Authors: Vasconcelos, Carlos Franciney Moreira^1,2 (AUTHOR) cfmvasconcelos@biof.ufrj.br, Ribas, Vinicius Toledo³ (AUTHOR) ribasvt@ufmg.br, Petrs-Silva, Hilda² (AUTHOR) cfmvasconcelos@biof.ufrj.br

Source: Cells (2073-4409). Sep2023, Vol. 12 Issue 17, p2155. 19p.

Subject Terms: *RNA regulation, *NEURODEGENERATION, *ALZHEIMER'S disease, *HUNTINGTON disease, *PARKINSON'S disease, *AMYOTROPHIC lateral sclerosis, *MOTOR neuron diseases

Gene Therapy Strategies for Glaucomatous Neurodegeneration

Authors: Lani-Louzada, Rafael, Dias, Mariana Santana, Linden, Rafael, Ribas, Vinicius Toledo, Petrs-Silva, Hilda

Source: Current gene therapy. 21(5):362-381

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140374608.0x000001&indx=1&recIds=ETOCvdc_100140374608.0x000001

AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson's Disease

Authors: Balke, Dirk, Tatenhorst, Lars, Dambeck, Vivian, Ribas, Vinicius Toledo, Vahsen, Björn F., Michel, Uwe, Bähr, Mathias, Lingor, Paul

Source: Molecular neurobiology. 57(2):685-697

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164107872.0x000001&indx=1&recIds=ETOCvdc_100164107872.0x000001

AAV-Mediated Expression of miR-17 Enhances Neurite and Axon Regeneration In Vitro.

Authors: Almeida, Raquel Alves, Ferreira, Carolina Gomes, Matos, Victor Ulysses Souza, Nogueira, Julia Meireles, Braga, Marina Pimenta, Caldi Gomes, Lucas, Jorge, Erika Cristina, Soriani, Frederico Marianetti, Michel, Uwe, Ribas, Vinicius Toledo

Source: International Journal of Molecular Sciences; Aug2024, Vol. 25 Issue 16, p9057, 16p

Subject Terms: CENTRAL nervous system injuries, CELL metabolism, GENE expression, NEURODEGENERATION, TRANSCRIPTION factors

AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo

Authors: Saal, Kim-Ann, Koch, Jan C., Tatenhorst, Lars, Szegő, Éva M., Ribas, Vinicius Toledo, Michel, Uwe, Bähr, Mathias, Tönges, Lars, Lingor, Paul

Source: In Neurobiology of Disease January 2015 73:150-162

AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo.

Authors: Ribas, Vinicius Toledo, Vahsen, Björn Friedhelm, Tatenhorst, Lars, Estrada, Veronica, Dambeck, Vivian, Almeida, Raquel Alves, Bähr, Mathias, Michel, Uwe, Koch, Jan Christoph, Müller, Hans Werner, Lingor, Paul

Source: Cell Death & Disease; Feb2021, Vol. 12 Issue 2, p1-14, 14p

Activation of c-Jun N-Terminal Kinase (JNK) during Mitosis in Retinal Progenitor Cells.

Authors: Ribas, Vinicius Toledo¹, Gonçcalves, Bruno Souza¹, Linden, Rafael¹, Chiarini, Luciana Barreto¹ chiarini@biof.ufrj.br

Source: PLoS ONE. Apr2012, Vol. 7 Issue 4, p1-9. 9p.

Subject Terms: *KINASES, *MITOSIS, *PROGENITOR cells, *LABORATORY rats, *PHOSPHORYLATION, *IMMUNOHISTOCHEMISTRY

Chapter 10 - Autophagy in the Degeneration of Optic Nerve and Spinal Cord Axons

Authors: Koch, Jan Christoph, Ribas, Vinicius Toledo, Lingor, Paul

Source: In Autophagy 2016:197-211

Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing

Authors: Vahsen, Björn Friedhelm, Ribas, Vinicius Toledo, Sundermeyer, Jonas, Boecker, Alexander, Dambeck, Vivian, Lenz, Christof, Shomroni, Orr, Caldi Gomes, Lucas, Tatenhorst, Lars, Barski, Elisabeth, Roser, Anna-Elisa, Michel, Uwe, Urlaub, Henning, Salinas, Gabriela, Bähr, Mathias, Koch, Jan Christoph, Lingor, Paul

Source: Cell Death and Differentiation; October 2020, Vol. 27 Issue: 10 p2810-2827, 18p

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Contributors

Authors: Airiau, Kelly, Aliwaini, Saeb, Annabi, Borhane, Armani, Andrea, Bleloch, Jenna, Caprio, Massimiliano, Chan, Eric, Chan, Leo Li-Ying, Coady, Michael J., De Meyer, Guido R.Y., De Munck, Dorien G., Djavaheri-Mergny, Mojgan, Gottlieb, Roberta A., Grootaert, Mandy O.J., Hayat, M.A., Higami, Yoshikazu, Jinwal, Umesh K., Kimani, Serah, Koch, Jan Christoph, Kuksin, Dmitry, Kurdi, Ammar, Lai, Ning, Lin, Bo, Lingor, Paul, Mao, Kai, Martinet, Wim, Marzolla, Vincenzo, Mizunoe, Yuhei, Narayan, Malathi, Okita, Naoyuki, Oliver, F. Javier, Patton, Wayne, Pratt, Jonathan, Prince, Sharon, Qiu, Jean, Ribas, Vinicius Toledo, Rodríguez-Vargas, José Manuel, Shen, Dee, Sudo, Yuka, Sun-Wada, Ge-Hong, Wada, Yoh, Wilkinson, Alisha R.

Source: In Autophagy 2016:lvii

The Role of Axonal Transport in Glaucoma.

Authors: Dias, Mariana Santana, Luo, Xiaoyue, Ribas, Vinicius Toledo, Petrs-Silva, Hilda, Koch, Jan Christoph

Source: International Journal of Molecular Sciences; Apr2022, Vol. 23 Issue 7, p3935-N.PAG, 24p

Subject Terms: AXONAL transport, RETINAL ganglion cells, VISUAL fields, GLAUCOMA, AXONS, OPTIC nerve, VISION disorders