Effects of Switching to Netarsudil/Latanoprost Fixed Dose Combination from Various Latanoprost Regimens: The Phase 4 MORE Study

Authors: Bacharach J, Sadri E, Sawhney G, Kopczynski C, Merchea MM

Source: Clinical Ophthalmology, Vol Volume 19, Pp 175-186 (2025)

Subject Terms: glaucoma, intraocular pressure, prostaglandin analog, rho-kinase inhibitor, Ophthalmology, RE1-994

File Description: electronic resource

Relation: https://www.dovepress.com/effects-of-switching-to-netarsudillatanoprost-fixed-dose-combination-f-peer-reviewed-fulltext-article-OPTH; https://doaj.org/toc/1177-5483

Access URL: https://doaj.org/article/00589d1a34f14672a4ab0c005d7a820c

Inhibition of pterygium cell fibrosis by the Rho kinase inhibitor

Authors: Jiannong Dai, Naga Pradeep Rayana, Michael Peng, Chenna Kesavulu Sugali, Devon H. Harvey, Kamesh Dhamodaran, Eric Yu, Joseph M. Dalloul, Shaohui Liu, Weiming Mao

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Subject Terms: Pterygium, Recurrence, Rho kinase inhibitor, Fibrosis, Health disparity, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3968a143b28f4916bdd40aded9639369

Evaluation of Rho kinase inhibitor effects on neuroprotection and neuroinflammation in an ex-vivo retinal explant model

Authors: Élodie Reboussin, Paul Bastelica, Ilyes Benmessabih, Arnaud Cordovilla, Cécile Delarasse, Annabelle Réaux-Le Goazigo, Françoise Brignole-Baudouin, Céline Olmière, Christophe Baudouin, Juliette Buffault, Stéphane Mélik Parsadaniantz

Source: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-21 (2024)

Subject Terms: Glaucoma, Rho kinase inhibitor, Neuroprotection, Immunomodulation, RNAseq analysis, Retinal explant, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/78539926c1e24f9ea37b32a906073d74

Rho kinase inhibitor Y-27632 and dual media culture approach promote the construction and transplantation of rabbit limbal epithelial cell sheets via cell spheroid culture and auto-bioprinting

Authors: Wang, Peiyuan ^{a, b, 1}, Shen, Shuhao ^{a, 1}, Guo, Yonglong ^c, Cao, Jixing ^a, Zhu, Deliang ^{d, e, f}, Xie, Mengyuan ^e, Yu, Quan ^g, Cui, Zekai ^h, Liu, Shiwei ^{a, i}, Zhang, Jun ^e, Chen, Jiansu ^{a, d, g, h, ⁎}

Source: In Acta Biomaterialia 1 March 2025 194:140-152

Drug- and Cell-Type-Specific Effects of ROCK Inhibitors as a Potential Cause of Reticular Corneal Epithelial Edema

Authors: Ursula Schlötzer-Schrehardt, Andreas Gießl, Matthias Zenkel, Alexander Bartsch, Naoki Okumura, Noriko Koizumi, Shigeru Kinoshita, Theofilos Tourtas, Friedrich E. Kruse

Source: Cells, Vol 14, Iss 4, p 258 (2025)

Subject Terms: reticular bullous corneal epithelial edema, honeycomb epithelial edema, Rho kinase inhibitor, ROCK inhibitor, ripasudil, netarsudil, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/4/258; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/ec412591f1bc4bf08b7e8f520b5fec70

Evaluating the efficacy of Rho kinase inhibitor eye drops in the management of corneal edema: A single-center retrospective cohort study

Authors: Itay Lavy, Nir Erdinest, Jamel Corredores, Denise Wajnsztajn, David Smadja

Source: Taiwan Journal of Ophthalmology, Vol 14, Iss 1, Pp 88-94 (2024)

Subject Terms: corneal edema, rho kinase inhibitor, ripasudil, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.e-tjo.org/article.asp?issn=2211-5056;year=2024;volume=14;issue=1;spage=88;epage=94;aulast=Lavy; https://doaj.org/toc/2211-5056; https://doaj.org/toc/2211-5072

Access URL: https://doaj.org/article/9924ae7f6c5e4585ae1922449cc97d9d

Double-Masked, Vehicle-Controlled, Randomized, Phase II Study of the Ocular Hypotensive Activity and Safety of VVN539 Ophthalmic Solution

Authors: David Wirta, MD, Xiao-Yan Li, MD, Wang Shen, PhD, Caroline Lu, MS, Gary D. Novack, PhD, William Christie, MD, Paul J. Hartman, MD, Lawrence Tafoya, MD, PhD, Navin Tekwani, MD

Source: Ophthalmology Science, Vol 4, Iss 2, Pp 100426- (2024)

Subject Terms: Glaucoma, Intraocular pressure, Ocular hypertension, Rho-kinase inhibitor, VVN539, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666914523001586; https://doaj.org/toc/2666-9145

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Efficacy of ripasudil in reducing intraocular pressure and medication score for ocular hypertension with inflammation and corticosteroid

Authors: Ryoji Yanai, Sho-Hei Uchi, Masaaki Kobayashi, Tomohiko Nagai, Shinichiro Teranishi, Makiko Wakuta, Kazuhiro Kimura

Source: International Journal of Ophthalmology, Vol 16, Iss 6, Pp 904-908 (2023)

Subject Terms: intraocular pressure, medication score, uveitis, glaucoma, rho kinase inhibitor, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://ies.ijo.cn/en_publish/2023/6/20230611.pdf; https://doaj.org/toc/2222-3959; https://doaj.org/toc/2227-4898

Access URL: https://doaj.org/article/631f275e6e0a4260a212831b6f9e77cd

Role of ripasudil as an adjunct treatment in the management of pseudoexfoliative glaucoma

Authors: Sumita Mohapatra, Subhodeep Thakur, Bijnya B Panda, Priti Das

Source: Indian Journal of Ophthalmology, Vol 71, Iss 7, Pp 2756-2759 (2023)

Subject Terms: intraocular pressure, pseudoexfoliative glaucoma, rho kinase inhibitor, ripasudil, rock inhibitor, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.ijo.in/article.asp?issn=0301-4738;year=2023;volume=71;issue=7;spage=2756;epage=2759;aulast=Mohapatra; https://doaj.org/toc/0301-4738; https://doaj.org/toc/1998-3689

Access URL: https://doaj.org/article/7c78ef60e13d49cf891a8834bffbab41

Intraocular Pressure and Ocular Hypertension

Contributors: Brusini, Paolo, Salvetat, Maria Letizia, Zeppieri, Marco

Subject Terms: intraocular pressure, serum calcium, female, ab interno trabeculotomy, glaucoma, incision in the Schlemm’s canal in degrees, post-surgical complication, neuroretinal rim reversal, Bruch’s membrane opening-minimum rim width, trabeculectomy, refractive error, neuroretina, myopia, intraocular pressure (IOP), tonometry, Goldmann applanation tonometer (GAT), central corneal thickness (CCT), ocular hypertension, higher-order aberrations, Kahook Dual Blade, age, central corneal thickness, Goldmann Applanation tonometer, non-contact tonometer, rebound tonometer, iCare, open angle glaucoma (OAG), Schlemm’s canal viscodilation, OMNI viscosurgical system, minimally invasive glaucoma surgeries (MIGS), trabeculotomy, cataract extraction, aqueous humor, GDF15, serum, intravitreal injection, anti-VEGF agents, trabecular meshwork, Matrigel, 3D culture, outflow, cytoskeleton, rho-kinase inhibitor, prostaglandin analog, childhood glaucoma, aphakia, pseudophakia, cataract surgery, lensectomy, management (or therapy), glaucoma drainage device, cyclodestruction, corneal biomechanics, ocular response analyzer, ORA, corneal hysteresis, non-penetrating deep sclerectomy, Esnoper V-2000 implant, glucocorticoids, safety profile, intranasal administration, inhaled administration, systemic administration, steroid response, canaloplasty, non-perforating surgical procedures, pseudoexfoliation glaucoma (PEXG), Schlemm’s canal, phase-sensitive optical coherent tomography, pulsatile motion, IOP fluctuation, primary open-angle glaucoma, intraocular pressure measurement, iCare tonometry, Perkins tonometry, standardized anaesthesia, corneal thickness, progression, risk stratification, XEN GelStent, corneal resistance factor, open-angle glaucoma, laser treatment, dropless treatment, thyroid-associated ophthalmopathy, extraocular muscle, magnetic resonance imaging, T2 relaxation time, Medicine and Nursing

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/92136
https://mdpi.com/books/pdfview/book/6013

Rho kinase inhibition attenuates LPS-induced acute lung injury in mice partly through cytoskeletal signaling mechanism

Authors: Li, Yan, Wu, Wei-kang

Source: 2011 IEEE International Symposium on IT in Medicine and Education IT in Medicine and Education (ITME), 2011 International Symposium on. 1:146-150 Dec, 2011

Relation: 2011 International Symposium on Information Technology in Medicine and Education (ITME 2011)

Safety, efficacy, and patient selection of ripasudil in patients with uncontrolled glaucoma with maximum conventional medical therapy

Authors: Jignesh Jethva, Purvi Bhagat, Kamini Prajapati, Gunjan Tank

Source: Indian Journal of Ophthalmology, Vol 70, Iss 6, Pp 2020-2023 (2022)

Subject Terms: glaucoma, hyperemia, rho kinase inhibitor, rock inhibitor, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=6;spage=2020;epage=2023;aulast=Jethva; https://doaj.org/toc/0301-4738; https://doaj.org/toc/1998-3689

Access URL: https://doaj.org/article/952e859e71d44d17b2fb5c18c40ec464

Advantages of Rho-associated kinases and their inhibitor fasudil for the treatment of neurodegenerative diseases

Authors: Qing Wang, Li-Juan Song, Zhi-Bin Ding, Zhi Chai, Jie-Zhong Yu, Bao-Guo Xiao, Cun-Gen Ma

Source: Neural Regeneration Research, Vol 17, Iss 12, Pp 2623-2631 (2022)

Subject Terms: alzheimer’s disease, cell-based therapy, central nervous system cells, fasudil, immunocytes, multiple sclerosis, parkinson’s disease, pericytes, rho kinase inhibitor, rho-associated kinases, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=12;spage=2623;epage=2631;aulast=Wang; https://doaj.org/toc/1673-5374

Access URL: https://doaj.org/article/8fde7ae105ca49a4b5499c0613b60fd5

Effectiveness of Netarsudil versus Brimonidine in Eyes already Being Treated with Glaucoma Medications at a Single Academic Tertiary Care Practice: A Comparative Study

Authors: Alex T. Pham, BS, Chris Bradley, PhD, Corinne Casey, OD, Henry D. Jampel, MD, Pradeep Y. Ramulu, MD, PhD, Jithin Yohannan, MD, MPH

Source: Current Therapeutic Research, Vol 98, Iss , Pp 100689- (2023)

Subject Terms: brimonidine, glaucoma, intraocular pressure, netarsudil, rho kinase inhibitor, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0011393X22000285; https://doaj.org/toc/0011-393X

Access URL: https://doaj.org/article/78545bddeff740ceb58e0243213ba967

Laminin-511-derived recombinant fragment and Rho kinase inhibitor Y-27632 facilitate serial cultivation of keratinocytes differentiated from human embryonic stem cells

Authors: Ryo Takagi, Akiko Tanuma-Takahashi, Saeko Akiyama, Wakana Kaneko, Chika Miura, Masayuki Yamato, Tatsuya Shimizu, Akihiro Umezawa

Source: Regenerative Therapy, Vol 18, Iss , Pp 242-252 (2021)

Subject Terms: Embryonic stem cells, Keratinocyte, Laminin-511, Rho kinase inhibitor, Medicine (General), R5-920, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352320421000572; https://doaj.org/toc/2352-3204

Access URL: https://doaj.org/article/88ff7d32c3e641688b4d609ff8dd4d87

A novel cell-based transplantation method using a Rho kinase inhibitor and a specific catheter device for the treatment of salivary gland damage after head and neck radiotherapy

Authors: Atsushi Kasamatsu, Reo Fukushima, Koki Nakamura, Kohei Kawasaki, Shusaku Yoshimura, Tomoyoshi Koyama, Chonji Fukumoto, Isao Miyamoto, Katsuhiro Uzawa

Source: Biochemistry and Biophysics Reports, Vol 32, Iss , Pp 101385- (2022)

Subject Terms: Radiotherapy, Head and neck cancer, Salivary gland, Cell-based transplantation, Rho kinase inhibitor, Auto-transplantation, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405580822001856; https://doaj.org/toc/2405-5808

Access URL: https://doaj.org/article/7aee4dd039dc4b9aa542493a601f5446

Therapeutic potential of Rho-associated kinase inhibitor Y27632 in corneal endothelial dysfunction: an in vitro and in vivo study

Authors: Yao-Wen Song, Jun-Yu Chen, Xu Li, Li Wang, Zhi-Qiang Pan

Source: International Journal of Ophthalmology, Vol 14, Iss 1, Pp 19-25 (2021)

Subject Terms: corneal endothelial dysfunction, rho kinase inhibitor, y-27632, porcine corneal endothelial cells, cell proliferation, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://ies.ijo.cn/en_publish/2021/1/20210103.pdf; https://doaj.org/toc/2222-3959; https://doaj.org/toc/2227-4898

Access URL: https://doaj.org/article/fb025b21d73c42b0bfbe79e050980df0

'Rapid and reversible alteration in corneal contour and power associated with Netarsudil/Latanoprost'

Authors: David Chung, Edward J. Meier

Source: American Journal of Ophthalmology Case Reports, Vol 26, Iss , Pp 101501- (2022)

Subject Terms: Glaucoma, Netarsudil, Rho kinase inhibitor, Radial keratotomy, Corneal topography, Reversible, Ophthalmology, RE1-994

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S245199362200247X; https://doaj.org/toc/2451-9936

Access URL: https://doaj.org/article/6087856e81f2460f9d43f95133fb0311

Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals

Authors: Esam M. Aboubakr, Ahmed R. N. Ibrahim, Fares E. M. Ali, Ahmed A. E. Mourad, Adel M. Ahmad, Amal Hofni

Source: Pharmaceuticals, Vol 15, Iss 11, p 1436 (2022)

Subject Terms: MTX hepatotoxicity, rho-kinase inhibitor, hepatic concentration, RP-HPLC technique, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/11/1436; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/0f7cf244b1c54ad68f1da5598a1a807d

Relief of vasospasm with fasudil after off-pump coronary artery bypass grafting: a case study

Authors: Akira Fujita, Hiroshi Kurazumi, Ryo Suzuki, Masaya Takahashi, Akihito Mikamo, Kimikazu Hamano

Source: Surgical Case Reports, Vol 4, Iss 1, Pp 1-4 (2018)

Subject Terms: Coronary artery vasospasm, Coronary artery bypass graft, Rho kinase inhibitor, Fasudil, Surgery, RD1-811

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40792-018-0481-9; https://doaj.org/toc/2198-7793

Access URL: https://doaj.org/article/f5bc6c9bcf2646b1bc7fa894e4791dfe