Crystal Morphology Modeling of Solvates and Hydrates of Organic Molecular Crystals: Olanzapine Solvate and Dihydrate

Authors: Sun, Yuanyuan, Reutzel-Edens, Susan M., Bhardwaj, Rajni M., Doherty, Michael F.

Source: Crystal growth & design. 21(9):4871-4877

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632062007&indx=1&recIds=ETOCRN632062007

Absorptive Dissolution Testing: An Improved Approach to Study the Impact of Residual Crystallinity on the Performance of Amorphous Formulations

Authors: Hate, Siddhi S., Reutzel-Edens, Susan M., Taylor, Lynne S.

Source: In Journal of Pharmaceutical Sciences March 2020 109(3):1312-1323

Influence of Drug—Silica Electrostatic Interactions on Drug Release from Mesoporous Silica-Based Oral Delivery Systems

Authors: Hate, Siddhi S., Reutzel-Edens, Susan M., Taylor, Lynne S.

Source: Molecular pharmaceutics. 17(9):3435-3446

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624715729&indx=1&recIds=ETOCRN624715729

Coamorphous Active Pharmaceutical Ingredient–Small Molecule Mixtures: Considerations in the Choice of Coformers for Enhancing Dissolution and Oral Bioavailability

Authors: Newman, Ann, Reutzel-Edens, Susan M., Zografi, George

Source: In Journal of Pharmaceutical Sciences January 2018 107(1):5-17

A Prolific Solvate Former, Galunisertib, under the Pressure of Crystal Structure Prediction, Produces Ten Diverse Polymorphs

Authors: Bhardwaj, Rajni M., McMahon, Jennifer A., Nyman, Jonas, Price, Louise S., Konar, Sumit, Oswald, Iain D. H., Pulham, Colin R., Price, Sarah L., Reutzel-Edens, Susan M.

Source: Journal of the American Chemical Society. 141(35):13887-13897

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621563085&indx=1&recIds=ETOCRN621563085

Accuracy and reproducibility in crystal structure prediction: the curious case of ROYElectronic supplementary information (ESI) available. CCDC 1877411. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8ce01902a

Authors: Nyman, Jonas, Yu, Lian, Reutzel-Edens, Susan M.

Source: CrystEngComm. 21(13):2080-2088

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100078798513.0x000001&indx=1&recIds=ETOCvdc_100078798513.0x000001

Insight into Amorphous Solid Dispersion Performance by Coupled Dissolution and Membrane Mass Transfer Measurements

Authors: Hate, Siddhi S., Reutzel-Edens, Susan M., Taylor, Lynne S.

Source: Molecular pharmaceutics. 16(1):448-461

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN618795640&indx=1&recIds=ETOCRN618795640

Inconvenient Truths about Solid Form Landscapes Revealed in the Polymorphs and Hydrates of Gandotinib

Authors: Braun, Doris E., McMahon, Jennifer A., Bhardwaj, Rajni M., Nyman, Jonas, Neumann, Marcus A., van de Streek, Jacco, Reutzel-Edens, Susan M.

Source: Crystal growth & design. 19(5):2947-2962

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631942580&indx=1&recIds=ETOCRN631942580

Modeling Olanzapine Solution Growth Morphologies

Authors: Sun, Yuanyuan, Tilbury, Carl J., Reutzel-Edens, Susan M., Bhardwaj, Rajni M., Li, Jinjin, Doherty, Michael F.

Source: Crystal growth & design. 18(2):905-911

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631824879&indx=1&recIds=ETOCRN631824879

Evaluating Competing Intermolecular Interactions through Molecular Electrostatic Potentials and Hydrogen-Bond Propensities

Authors: Sandhu, Bhupinder, McLean, Ann, Sinha, Abhijeet S., Desper, John, Sarjeant, Amy A., Vyas, Shyam, Reutzel-Edens, Susan M., Aakeröy, Christer B.

Source: Crystal growth & design. 18(1):466-478

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631824339&indx=1&recIds=ETOCRN631824339

The potential of computed crystal energy landscapes to aid solid-form development

Authors: Price, Sarah L., Reutzel-Edens, Susan M.

Source: In Drug Discovery Today June 2016 21(6):912-923

Absorptive Dissolution Testing of Supersaturating Systems: Impact of Absorptive Sink Conditions on Solution Phase Behavior and Mass Transport

Authors: Hate, Siddhi S., Reutzel-Edens, Susan M., Taylor, Lynne S.

Source: Molecular pharmaceutics. 14(11):4052-4063

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN613727567&indx=1&recIds=ETOCRN613727567

Direct Observation of Templated Two-Step Nucleation Mechanism during Olanzapine Hydrate Formation

Authors: Warzecha, Monika, Guo, Rui, Bhardwaj, Rajni M., Reutzel-Edens, Susan M., Price, Sarah L., Lamprou, Dimitrios A., Florence, Alastair J.

Source: Crystal growth & design. 17(12):6382-6393

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631784329&indx=1&recIds=ETOCRN631784329

Unraveling Complexity in the Solid Form Screening of a Pharmaceutical Salt: Why so Many Forms? Why so Few?

Authors: Braun, Doris E., Lingireddy, Sreenivas R., Beidelschies, Mark D., Guo, Rui, Müller, Peter, Price, Sarah L., Reutzel-Edens, Susan M.

Source: Crystal growth & design. 17(10):5349-5365

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631783167&indx=1&recIds=ETOCRN631783167

A molecular picture of the problems in ensuring structural purity of tazofelone

Authors: Price, Louise S., McMahon, Jennifer A., Lingireddy, Sreenivas R., Lau, Suk-Fai, Diseroad, Benjamin A., Price, Sarah L., Reutzel-Edens, Susan M.

Source: In Journal of Molecular Structure 25 December 2014 1078:26-42

Diabat method for polymorph free energies: Extension to molecular crystals.

Authors: Kamat, Kartik, Guo, Rui, Reutzel-Edens, Susan M., Price, Sarah L., Peters, Baron

Source: Journal of Chemical Physics; 12/28/2020, Vol. 153 Issue 24, p1-11, 11p

Subject Terms: MONTE Carlo method, MOLECULAR crystals, THERMODYNAMIC cycles, CARBAMAZEPINE

Supersaturation Potential of Salt, Co-Crystal, and Amorphous Forms of a Model Weak Base

Authors: Sousa, Luis Almeida e, Reutzel-Edens, Susan M., Stephenson, Gregory A., Taylor, Lynne S.

Source: Crystal growth & design. 16(2):737-748

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631743819&indx=1&recIds=ETOCRN631743819

Do metastable polymorphs always grow faster? Measuring and comparing growth kinetics of three polymorphs of tolfenamic acid.

Authors: Sacchi, Pietro, Neoptolemou, Petros, Davey, Roger J., Reutzel-Edens, Susan M., Cruz-Cabeza, Aurora J.

Source: Chemical Science; 11/14/2023, Vol. 14 Issue 42, p11775-11789, 15p

Predicting crystal form stability under real-world conditions.

Authors: Firaha, Dzmitry, Liu, Yifei Michelle, van de Streek, Jacco, Sasikumar, Kiran, Dietrich, Hanno, Helfferich, Julian, Aerts, Luc, Braun, Doris E., Broo, Anders, DiPasquale, Antonio G., Lee, Alfred Y., Le Meur, Sarah, Nilsson Lill, Sten O., Lunsmann, Walter J., Mattei, Alessandra, Muglia, Pierandrea, Putra, Okky Dwichandra, Raoui, Mohamed, Reutzel-Edens, Susan M., Rome, Sandrine

Source: Nature; Nov2023, Vol. 623 Issue 7986, p324-328, 5p

Interplay of Adsorption, Supersaturation and the Presence of an Absorptive Sink on Drug Release from Mesoporous Silica-Based Formulations

Authors: Hate, Siddhi S., Reutzel-Edens, Susan M., Taylor, Lynne S.

Source: PHARMACEUTICAL RESEARCH. 37(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171554939.0x000001&indx=1&recIds=ETOCvdc_100171554939.0x000001