Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor

Authors: Lörinczi, Éva, Bhargava, Yogesh, Marino, Stephen F., Taly, Antoine, Kaczmarek-Hájek, Karina, Barrantes-Freer, Alonso, Dutertre, Sébastien, Grutter, Thomas, Rettinger, Jürgen, Nicke, Annette

Source: Proceedings of the National Academy of Sciences of the United States of America, 2012 Jul 01. 109(28), 11396-11401.

Access URL: https://www.jstor.org/stable/41684754

A Functional P2X7 Splice Variant with an Alternative Transmembrane Domain 1 Escapes Gene Inactivation in P2X7 Knock-out Mice

Authors: Nicke, Annette, Kuan, Yung-Hui, Masin, Marianela, Rettinger, Jürgen, Marquez-Klaka, Benjamin, Bender, Olaf, Górecki, Dariusz C. ^**, Murrell-Lagnado, Ruth D., Soto, Florentina

Source: In Journal of Biological Chemistry 18 September 2009 284(38):25813-25822

The Suramin Analog 4,4′,4″,4″′-(Carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic Acid (NF110) Potently Blocks P2X3 Receptors: Subtype Selectivity Is Determined by Location of Sulfonic Acid Groups

Authors: Hausmann, Ralf, Rettinger, Jürgen, Gerevich, Zoltan, Meis, Sabine, Kassack, Matthias U., Illes, Peter, Lambrecht, Günter, Schmalzing, Günther ^*

Source: In Molecular Pharmacology June 2006 69(6):2058-2067

Profiling at recombinant homomeric and heteromeric rat P2X receptors identifies the suramin analogue NF449 as a highly potent P2X 1 receptor antagonist

Authors: Rettinger, Jürgen, Braun, Kirsten, Hochmann, Henrike, Kassack, Matthias U., Ullmann, Heiko, Nickel, Peter, Schmalzing, Günther, Lambrecht, Günter

Source: In Neuropharmacology 2005 48(3):461-468

Activation and Desensitization of the Recombinant P2X1 Receptor at Nanomolar ATP Concentrations.

Authors: Rettinger, Jürgen, Schmalzing, Günther

Source: Journal of General Physiology; May 2003, Vol. 121 Issue 5, p451-461, 11p

Desensitization Masks Nanomolar Potency of ATP for the P2X1 Receptor

Authors: Rettinger, Jürgen ^‡, Schmalzing, Günther ^{§, ¶}

Source: In Journal of Biological Chemistry February 2004 279(8):6426-6433

Trimeric Architecture of Homomeric P2X 2 and Heteromeric P2X 1+2 Receptor Subtypes

Authors: Aschrafi, Armaz ^†, Sadtler, Sven, Niculescu, Cristina, Rettinger, Jürgen ^†, Schmalzing, Günther ^*

Source: In Journal of Molecular Biology 2004 342(1):333-343

Roles of Individual N-Glycans for ATP Potency and Expression of the Rat P2X1 Receptor

Authors: Rettinger, Jürgen ^‡, Aschrafi, Armaz ^‡, Schmalzing, Günther ^{§, ¶}

Source: In Journal of Biological Chemistry 27 October 2000 275(43):33542-33547

The suramin analogue NF279 is a novel and potent antagonist selective for the P2X 1 receptor

Authors: Rettinger, Jürgen ^*, Schmalzing, Günther, Damer, Susanne, Müller, Gregor, Nickel, Peter, Lambrecht, Günter

Source: In Neuropharmacology 2000 39(11):2044-2053

Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors.

Authors: Marquez-Klaka, Benjamin¹, Rettinger, Jürgen², Nicke, Annette¹ anicke@gwdg.de

Source: European Biophysics Journal. Mar2009, Vol. 38 Issue 3, p329-338. 10p. 2 Diagrams, 1 Chart, 1 Graph.

Subject Terms: *CATIONS, *CYSTEINE proteinases, *BINDING sites, *DIMERS, *PROTEINASES

Chapter 6 Evolving view of quaternary structures of ligand-gated ion channels

Authors: Nicke, Annette, Rettinger, Jürgen, Büttner, Cora, Eichele, Annette, Lambrech, Günter, Schmalzing, Günther

Source: In Progress in Brain Research 1999 120:61-80

Chapter 9 Novel ligands for P2 receptor subtypes in innervated tissues

Authors: Lambrecht, Günter, Damer, Susanne, Niebel, Beate, Czeche, Sittah, Nickel, Peter, Rettinger, Jürgen, Schmalzing, Günther, Mutschler, Ernst

Source: In Progress in Brain Research 1999 120:107-117

Validation of Alexa-647-ATP as a powerful tool to study P2X receptor ligand binding and desensitization

Authors: Bhargava, Yogesh, Nicke, Annette, Rettinger, Jürgen

Source: In Biochemical and Biophysical Research Communications 23 August 2013 438(2):295-300

BackMatter.

Authors: Rettinger, Jürgen, Schwarz, Silvia, Schwarz, Wolfgang

Source: Electrophysiology; 2016, p159-162, 4p

Appendix.

Authors: Rettinger, Jürgen, Schwarz, Silvia, Schwarz, Wolfgang

Source: Electrophysiology; 2016, p139-157, 19p

Examples of Applications of Electrophysiology.

Authors: Rettinger, Jürgen, Schwarz, Silvia, Schwarz, Wolfgang

Source: Electrophysiology; 2016, p119-138, 20p

Carrier-Mediated Transport.

Authors: Rettinger, Jürgen, Schwarz, Silvia, Schwarz, Wolfgang

Source: Electrophysiology; 2016, p105-118, 14p

Theory of Excitability.

Authors: Rettinger, Jürgen, Schwarz, Silvia, Schwarz, Wolfgang

Source: Electrophysiology; 2016, p81-103, 23p

Ion-Selective Channels.

Authors: Rettinger, Jürgen, Schwarz, Silvia, Schwarz, Wolfgang

Source: Electrophysiology; 2016, p69-79, 11p

Automated Electrophysiology.

Authors: Rettinger, Jürgen, Schwarz, Silvia, Schwarz, Wolfgang

Source: Electrophysiology; 2016, p63-67, 5p