Investigation of the mechanism of action of mefloquine and derivatives against the parasite Echinococcus multilocularis

Authors: Roman Memedovski, Matías Preza, Joachim Müller, Tobias Kämpfer, Reto Rufener, Marcus Vinicius Nora de Souza, Emerson Teixeira da Silva, Gabriel Fernandes de Andrade, Sophie Braga, Anne-Christine Uldry, Natasha Buchs, Manfred Heller, Britta Lundström-Stadelmann

Source: International Journal for Parasitology: Drugs and Drug Resistance, Vol 21, Iss , Pp 114-124 (2023)

Subject Terms: Echinococcus multilocularis, Alveolar echinococcosis, Mefloquine, Structure-activity relationship (SAR), Mode of action, nLC-MS/MS, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320723000106; https://doaj.org/toc/2211-3207

Access URL: https://doaj.org/article/89a49aeeca2f46a99fa3bbefacf831fb

Handling method affects measures of anxiety, but not chronic stress in mice

Authors: Janja Novak, Ivana Jaric, Marianna Rosso, Reto Rufener, Chadi Touma, Hanno Würbel

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e3b481ba6a19498c93a5d0dccdf0d81b

Targeted and non-targeted proteomics to characterize the parasite proteins of Echinococcus multilocularis metacestodes

Authors: Joachim Müller, Matías Preza, Marc Kaethner, Reto Rufener, Sophie Braga, Anne-Christine Uldry, Manfred Heller, Britta Lundström-Stadelmann

Source: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

Subject Terms: cestodes, model system, targeted proteomics, transport, echinococcosis, untargeted proteomics, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2023.1170763/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/7424e9620f4041edb08887ce551f8b69

The rearing environment persistently modulates mouse phenotypes from the molecular to the behavioural level.

Authors: Ivana Jaric, Bernhard Voelkl, Melanie Clerc, Marc W Schmid, Janja Novak, Marianna Rosso, Reto Rufener, Vanessa Tabea von Kortzfleisch, S Helene Richter, Manuela Buettner, André Bleich, Irmgard Amrein, David P Wolfer, Chadi Touma, Shinichi Sunagawa, Hanno Würbel

Source: PLoS Biology, Vol 20, Iss 10, p e3001837 (2022)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/cc627cad13334405af451b4e005d6522

Drug repurposing applied: Activity of the anti-malarial mefloquine against Echinococcus multilocularis

Authors: Britta Lundström-Stadelmann, Reto Rufener, Andrew Hemphill

Source: International Journal for Parasitology: Drugs and Drug Resistance, Vol 13, Iss , Pp 121-129 (2020)

Subject Terms: Alveolar echinococcosis, Metacestode, MMV665807, Niclosamide, Atovaquone, Energy-metabolism, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320720300154; https://doaj.org/toc/2211-3207

Access URL: https://doaj.org/article/016d97ae6f0c4f529db19ffda9cda496

Monocyte biology conserved across species: Functional insights from cattle

Authors: Stephanie C. Talker, G. Tuba Barut, Heidi E.L. Lischer, Reto Rufener, Lilly von Münchow, Rémy Bruggmann, Artur Summerfield

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: bovine monocyte subsets, classical monocytes, intermediate monocytes, nonclassical monocytes, transcriptome, single-cell RNA sequencing (scRNA-seq), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.889175/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/7f3910f9bb254742bf6e108c4517f8f6

Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis

Authors: Reto Rufener, Luca Dick, Laura D'Ascoli, Dominic Ritler, Amani Hizem, Timothy N.C. Wells, Andrew Hemphill, Britta Lundström-Stadelmann

Source: International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 3, Pp 440-450 (2018)

Subject Terms: Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320718301222; https://doaj.org/toc/2211-3207

Access URL: https://doaj.org/article/db22c648a0384f94987a703c8a6fb840

Activity of mefloquine and mefloquine derivatives against Echinococcus multilocularis

Authors: Reto Rufener, Dominic Ritler, Jana Zielinski, Luca Dick, Emerson Teixeira da Silva, Adriele da Silva Araujo, Deborah Elisabeth Joekel, David Czock, Christine Goepfert, Adriana Marques Moraes, Marcus Vinicius Nora de Souza, Joachim Müller, Meike Mevissen, Andrew Hemphill, Britta Lundström-Stadelmann

Source: International Journal for Parasitology: Drugs and Drug Resistance, Vol 8, Iss 2, Pp 331-340 (2018)

Subject Terms: Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320718300617; https://doaj.org/toc/2211-3207

Access URL: https://doaj.org/article/2b3f903ef08f4147bc06e659672883ea

The importance of being parasiticidal… an update on drug development for the treatment of alveolar echinococcosis

Authors: Britta Lundström-Stadelmann, Reto Rufener, Dominic Ritler, Raphael Zurbriggen, Andrew Hemphill

Source: Food and Waterborne Parasitology, Vol 15, Iss , Pp - (2019)

Subject Terms: Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405676618300453; https://doaj.org/toc/2405-6766

Access URL: https://doaj.org/article/25414a19d0c44ab38e45faedabd56a51

Maca against Echinococcosis?—A Reverse Approach from Patient to In Vitro Testing

Authors: Tanja Karpstein, Sheena Chaudhry, Solange Bresson-Hadni, Michael Hayoz, Ghalia Boubaker, Andrew Hemphill, Reto Rufener, Marc Kaethner, Isabelle Schindler, Yolanda Aebi, Antonio Sa Cunha, Carlo R. Largiadèr, Britta Lundström-Stadelmann

Source: Pathogens, Vol 10, Iss 10, p 1335 (2021)

Subject Terms: Lepidium meyenii, Echinococcus multilocularis, Maca, alveolar echinococcosis, treatment, phytotherapy, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/10/10/1335; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/4cd0299839024bd1a837f47aafb08760

Author Correction: In vitro metabolomic footprint of the Echinococcus multilocularis metacestode

Authors: Dominic Ritler, Reto Rufener, Jia V. Li, Urs Kämpfer, Joachim Müller, Claudia Bühr, Stefan Schürch, Britta Lundström-Stadelmann

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a6d3abf99ccd446183143365c78e87cf

Development of a movement-based in vitro screening assay for the identification of new anti-cestodal compounds.

Authors: Dominic Ritler, Reto Rufener, Heinz Sager, Jacques Bouvier, Andrew Hemphill, Britta Lundström-Stadelmann

Source: PLoS Neglected Tropical Diseases, Vol 11, Iss 5, p e0005618 (2017)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5448807?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/40ac11d27b0843eea2f64a4e538a54e1

Screening of the Open Source Malaria Box Reveals an Early Lead Compound for the Treatment of Alveolar Echinococcosis.

Authors: Britta Stadelmann, Reto Rufener, Denise Aeschbacher, Markus Spiliotis, Bruno Gottstein, Andrew Hemphill

Source: PLoS Neglected Tropical Diseases, Vol 10, Iss 3, p e0004535 (2016)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0004535&type=printable; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/361f2ed80a4642cc863dcd09cecc86ed