Safety and immunogenicity of an inactivated recombinant Newcastle disease virus vaccine expressing SARS-CoV-2 spike: A randomised, comparator-controlled, phase 2 trial

Authors: Thiem, Vu Dinh ^a, Anh, Dang Duc ^a, Ha, Vu Hai ^a, Van Thom, Nguyen ^b, Thang, Tran Cong ^c, Mateus, Jose ^d, Carreño, Juan Manuel ^{e, f}, Raghunandan, Rama ^{g, ⁎}, Huong, Nguyen Mai ^c, Mercer, Laina D. ^g, Flores, Jorge ^g, Escarrega, E. Alexandar ^d, Raskin, Ariel ^{e, f}, Thai, Duong Huu ^h, Van Be, Le ^h, Sette, Alessandro ^{d, i}, Innis, Bruce L. ^g, Krammer, Florian ^{e, f, j, ⁎⁎}, Weiskopf, Daniela ^{d, i, ⁎⁎⁎}

Source: In Vaccine 12 January 2025 44

Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination

Authors: Clark, Jordan J. ^{1, 2}, Hoxie, Irene ^{1, 2}, Adelsberg, Daniel C. ¹, Sapse, Iden A. ¹, Andreata-Santos, Robert ^{1, 2, 3}, Yong, Jeremy S. ^{1, 2}, Amanat, Fatima ¹, Tcheou, Johnstone ^{1, 2}, Raskin, Ariel ^{1, 2}, Singh, Gagandeep ^{1, 2}, González-Domínguez, Irene ¹, Edgar, Julia E. ⁴, Bournazos, Stylianos ⁴, Sun, Weina ¹, Carreño, Juan Manuel ^{1, 2}, Simon, Viviana ^{1, 2, 5, 6, 7}, Ellebedy, Ali H. ^{8, 9, 10}, Bajic, Goran ¹, Krammer, Florian ^{1, 2, 5, 11, 12, ∗}

Source: In Cell Reports 26 November 2024 43(11)

SARS-CoV-2 BA.1 and BA.2 breakthrough infections boost antibody responses to early Omicron subvariants but not BQ.1.1 or XBB.1.5

Authors: Andre, Dalles, Bermúdez-González, Maria C., Bielak, Dominika, Cai, Gianna, Cognigni, Christian, Chen, Yuexing, Kang, Hyun Min, Kleiner, Giulio, Lyttle, Neko, Mauldin, Jacob, Morris, Sara, Nardulli, Jessica, Oostenink, Annika, Salimbangon, Ashley-Beathrese, Srivastava, Komal, Sullivan, Leeba, Van Kesteren, Morgan, Abbad, Anass, Yellin, Temima, Singh, Gagandeep, Fried, Miriam, Raskin, Ariel, Tcheou, Johnstone, Monahan, Brian, Gleason, Charles, Simon, Viviana, Carreño, Juan Manuel, Krammer, Florian

Source: In Cell Reports Medicine 19 March 2024 5(3)

Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants

Authors: Duty, J. Andrew, Kraus, Thomas, Zhou, Heyue, Zhang, Yanliang, Shaabani, Namir, Yildiz, Soner, Du, Na, Singh, Alok, Miorin, Lisa, Li, Donghui, Stegman, Karen, Ophir, Sabrina, Cao, Xia, Atanasoff, Kristina, Lim, Reyna, Mena, Ignacio, Bouvier, Nicole M., Kowdle, Shreyas, Carreño, Juan Manuel, Rivero-Nava, Laura, Raskin, Ariel, Moreno, Elena, Johnson, Sachi, Rathnasinghe, Raveen, Pai, Chin I., Kehrer, Thomas, Cabral, Elizabeth Paz, Jangra, Sonia, Healy, Laura, Singh, Gagandeep, Warang, Prajakta, Simon, Viviana, Sordillo, Emilia Mia, van Bakel, Harm, Liu, Yonghong, Sun, Weina, Kerwin, Lisa, Teijaro, John, Schotsaert, Michael, Krammer, Florian, Bresson, Damien, García-Sastre, Adolfo, Fu, Yanwen, Lee, Benhur, Powers, Colin, Moran, Thomas, Ji, Henry, Tortorella, Domenico, Allen, Robert

Source: In Med 14 October 2022 3(10):705-721

Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study

Authors: Ozonoff, Al, Schaenman, Joanna, Jayavelu, Naresh Doni, Milliren, Carly E., Calfee, Carolyn S., Cairns, Charles B., Kraft, Monica, Baden, Lindsey R., Shaw, Albert C., Krammer, Florian, van Bakel, Harm, Esserman, Denise A., Liu, Shanshan, Sesma, Ana Fernandez, Simon, Viviana, Hafler, David A., Montgomery, Ruth R., Kleinstein, Steven H., Levy, Ofer, Bime, Chris, Haddad, Elias K., Erle, David J., Pulendran, Bali, Nadeau, Kari C., Davis, Mark M, Hough, Catherine L., Messer, William B., Higuita, Nelson I. Agudelo, Metcalf, Jordan P., Atkinson, Mark A., Brakenridge, Scott C., Corry, David, Kheradmand, Farrah, Ehrlich, Lauren I.R., Melamed, Esther, McComsey, Grace A., Sekaly, Rafick, Diray-Arce, Joann, Peters, Bjoern, Augustine, Alison D., Reed, Elaine F., McEnaney, Kerry, Barton, Brenda, Lentucci, Claudia, Saluvan, Mehmet, Chang, Ana C., Hoch, Annmarie, Albert, Marisa, Shaheen, Tanzia, Kho, Alvin T., Thomas, Sanya, Chen, Jing, Murphy, Maimouna D., Cooney, Mitchell, Presnell, Scott, Fragiadakis, Gabriela K., Patel, Ravi, Guan, Leying, Gygi, Jeremy, Pawar, Shrikant, Brito, Anderson, Khalil, Zain, Maguire, Cole, Fourati, Slim, Overton, James A., Vita, Randi, Westendorf, Kerstin, Salehi-Rad, Ramin, Leligdowicz, Aleksandra, Matthay, Michael A., Singer, Jonathan P., Kangelaris, Kirsten N., Hendrickson, Carolyn M., Krummel, Matthew F., Langelier, Charles R., Woodruff, Prescott G., Powell, Debra L., Kim, James N., Simmons, Brent, Goonewardene, I. Michael, Smith, Cecilia M., Martens, Mark, Mosier, Jarrod, Kimura, Hiroki, Sherman, Amy C., Walsh, Stephen R., Issa, Nicolas C., Dela Cruz, Charles, Farhadian, Shelli, Iwasaki, Akiko, Ko, Albert I., Chinthrajah, Sharon, Ahuja, Neera, Rogers, Angela J., Artandi, Maja, Siegel, Sarah A.R., Lu, Zhengchun, Drevets, Douglas A., Brown, Brent R., Anderson, Matthew L., Guirgis, Faheem W., Thyagarajan, Rama V., Rousseau, Justin F., Wylie, Dennis, Busch, Johanna, Gandhi, Saurin, Triplett, Todd A., Yendewa, George, Giddings, Olivia, Anderson, Evan J., Mehta, Aneesh K., Sevransky, Jonathan E., Khor, Bernard, Rahman, Adeeb, Stadlbauer, Daniel, Dutta, Jayeeta, Xie, Hui, Kim-Schulze, Seunghee, Gonzalez-Reiche, Ana Silvia, van de Guchte, Adriana, Farrugia, Keith, Khan, Zenab, Maecker, Holden T., Elashoff, David, Brook, Jenny, Ramires-Sanchez, Estefania, Llamas, Megan, Rivera, Adreanne, Perdomo, Claudia, Ward, Dawn C., Magyar, Clara E., Fulcher, Jennifer A., Abe-Jones, Yumiko, Asthana, Saurabh, Beagle, Alexander, Bhide, Sharvari, Carrillo, Sidney A., Chak, Suzanna, Ghale, Rajani, Gonzalez, Ana, Jauregui, Alejandra, Jones, Norman, Lea, Tasha, Lee, Deanna, Lota, Raphael, Milush, Jeff, Nguyen, Viet, Pierce, Logan, Prasad, Priya A., Rao, Arjun, Samad, Bushra, Shaw, Cole, Sigman, Austin, Sinha, Pratik, Ward, Alyssa, Willmore, Andrew, Zhan, Jenny, Rashid, Sadeed, Rodriguez, Nicklaus, Tang, Kevin, Altamirano, Luz Torres, Betancourt, Legna, Curiel, Cindy, Sutter, Nicole, Paz, Maria Tercero, Tietje-Ulrich, Gayelan, Leroux, Carolyn, Connors, Jennifer, Bernui, Mariana, Kutzler, Michel A., Edwards, Carolyn, Lee, Edward, Lin, Edward, Croen, Brett, Semenza, Nicholas C., Rogowski, Brandon, Melnyk, Nataliya, Woloszczuk, Kyra, Cusimano, Gina, Bell, Mathew R., Furukawa, Sara, McLin, Renee, Marrero, Pamela, Sheidy, Julie, Tegos, George P., Nagle, Crystal, Mege, Nathan, Ulring, Kristen, Seyfert-Margolis, Vicki, Conway, Michelle, Francisco, Dave, Molzahn, Allyson, Erickson, Heidi, Wilson, Connie Cathleen, Schunk, Ron, Sierra, Bianca, Hughes, Trina, Smolen, Kinga, Desjardins, Michael, van Haren, Simon, Mitre, Xhoi, Cauley, Jessica, Li, Xiaofang, Tong, Alexandra, Evans, Bethany, Montesano, Christina, Licona, Jose Humberto, Krauss, Jonathan, Chang, Jun Bai Park, Izaguirre, Natalie, Chaudhary, Omkar, Coppi, Andreas, Fournier, John, Mohanty, Subhasis, Muenker, M. Catherine, Nelson, Allison, Raddassi, Khadir, Rainone, Michael, Ruff, William E., Salahuddin, Syim, Schulz, Wade L., Vijayakumar, Pavithra, Wang, Haowei, Wunder Jr., Elsio, Young, H. Patrick, Zhao, Yujiao, Saksena, Miti, Altman, Deena, Kojic, Erna, Srivastava, Komal, Eaker, Lily Q., Bermúdez-González, Maria C., Beach, Katherine F., Sominsky, Levy A., Azad, Arman R., Carreño, Juan Manuel, Singh, Gagandeep, Raskin, Ariel, Tcheou, Johnstone, Bielak, Dominika, Kawabata, Hisaaki, Mulder, Lubbertus CF, Kleiner, Giulio, Lee, Alexandra S., Do, Evan Do, Fernandes, Andrea, Manohar, Monali, Hagan, Thomas, Blish, Catherine A., Din, Hena Naz, Roque, Jonasel, Yang, Samuel, Brunton, Amanda, Sullivan, Peter E., Strnad, Matthew, Lyski, Zoe L., Coulter, Felicity J., Booth, J. Leland, Sinko, Lauren A., Moldawer, Lyle L., Borresen, Brittany, Roth-Manning, Brittney, Song, Li-Zhen, Nelson, Ebony, Lewis-Smith, Megan, Smith, Jacob, Tipan, Pablo Guaman, Siles, Nadia, Bazzi, Sam, Geltman, Janelle, Hurley, Kerin, Gabriele, Gio, Sieg, Scott, Vaysman, Tatyana, Bristow, Laurel, Hussaini, Laila, Hellmeister, Kieffer, Samaha, Hady, Cheng, Andrew, Spainhour, Christine, Scherer, Erin M., Johnson, Brandi, Bechnak, Amer, Ciric, Caroline R., Hewitt, Lauren, Carter, Erin, Mcnair, Nina, Panganiban, Bernadine, Huerta, Christopher, Usher, Jacob, Ribeiro, Susan Pereira, Altman, Matthew C., Becker, Patrice M., Rouphael, Nadine, Bime, Christian, Davis, Mark M.

Source: In eBioMedicine September 2022 83

Evidence for retained spike-binding and neutralizing activity against emerging SARS-CoV-2 variants in serum of COVID-19 mRNA vaccine recipients

Authors: Carreño, Juan Manuel, Alshammary, Hala, Singh, Gagandeep, Raskin, Ariel, Amanat, Fatima, Amoako, Angela, Gonzalez-Reiche, Ana Silvia, van de Guchte, Adriana, study group, PARIS, Srivastava, Komal, Sordillo, Emilia Mia, Sather, D. Noah, van Bakel, Harm, Krammer, Florian, Simon, Viviana

Source: In EBioMedicine November 2021 73

SARS-CoV-2 serosurvey across multiple waves of the COVID-19 pandemic in New York City between 2020–2023.

Authors: Carreño, Juan Manuel, Wagner, Abram L., Monahan, Brian, Singh, Gagandeep, Floda, Daniel, Gonzalez-Reiche, Ana S., Tcheou, Johnstone, Raskin, Ariel, Bielak, Dominika, Morris, Sara, Fried, Miriam, Yellin, Temima, Sullivan, Leeba, Amanat, Fatima, Arunkumar, Guha Asthagiri, Capuano, Christina, Ehrenhaus, Jordan, Fabre, Shelcie, Hernandez, Matthew M., Jiang, Kaijun

Source: Nature Communications; 7/11/2024, Vol. 15 Issue 1, p1-10, 10p

Subject Terms: COVID-19, SARS-CoV-2, COVID-19 pandemic

Geographic Terms: NEW York (N.Y.)

Longitudinal COVID-19-vaccination-induced antibody responses and Omicron neutralization in patients with lung cancer

Authors: Andre, D., Alshammary, H., van Bakel, H., Bermúdez-González, M.C., Cai, G., Cognigni, C., Floda, D., Firpo, A., Kleiner, G., Lyttle, N., Mendez, W., Mulder, L.C.F., Oostenink, A., Rooker, A., Salimbangon, A., Saksena, M., Sominsky, L., Sordillo, E.M., Mack, Philip C., Gomez, Jorge E., Rodilla, Ananda M., Carreño, Juan Manuel, Hsu, Chih-Yuan, Rolfo, Christian, Meshulami, Noy, Moore, Amy, Brody, Rachel I., King, Jennifer C., Treatman, Jacquelyn, Lee, Sooyun, Raskin, Ariel, Srivastava, Komal, Gleason, Charles R., de Miguel-Perez, Diego, Tcheou, Johnstone, Bielak, Dominika, Acharya, Rashmi, Gerber, David E., Rohs, Nicholas, Henschke, Claudia I., Yankelevitz, David F., Simon, Viviana, Minna, John D., Bunn, Paul A., Jr., García-Sastre, Adolfo, Krammer, Florian, Shyr, Yu, Hirsch, Fred R.

Source: In Cancer Cell 13 June 2022 40(6):575-577

An inactivated NDV-HXP-S COVID-19 vaccine elicits a higher proportion of neutralizing antibodies in humans than mRNA vaccination.

Authors: Carreño, Juan Manuel, Raskin, Ariel, Singh, Gagandeep, Tcheou, Johnstone, Kawabata, Hisaaki, Gleason, Charles, Srivastava, Komal, Vigdorovich, Vladimir, Dambrauskas, Nicholas, Gupta, Sneh Lata, González Domínguez, Irene, Martinez, Jose Luis, Slamanig, Stefan, Sather, D. Noah, Raghunandan, Rama, Wirachwong, Ponthip, Muangnoicharoen, Sant, Pitisuttithum, Punnee, Wrammert, Jens, Suthar, Mehul S.

Source: Science Translational Medicine; 2/15/2023, Vol. 15 Issue 683, p1-10, 10p

Subject Terms: IMMUNOGLOBULINS, COVID-19 vaccines, INFLUENZA vaccines, VACCINATION, CLINICAL trials, NEWCASTLE disease vaccines, VIRAL antibodies

Geographic Terms: THAILAND

SARS-CoV-2 vaccination induces mucosal antibody responses in previously infected individuals.

Authors: Sano, Kaori, Bhavsar, Disha, Singh, Gagandeep, Floda, Daniel, Srivastava, Komal, Gleason, Charles, PARIS Study Group, Amoako, Angela A., Andre, Dalles, Beach, Katherine F., Bermúdez-González, Maria C., Cai, Gianna, Cognigni, Christian, Kawabata, Hisaaki, Kleiner, Giulio, Lyttle, Neko, Mendez, Wanni, Mulder, Lubbertus C. F., Oostenink, Annika, Raskin, Ariel

Source: Nature Communications; 9/1/2022, Vol. 13 Issue 1, p1-8, 8p

Subject Terms: SARS-CoV-2, IMMUNOGLOBULINS, ANTIBODY formation, COVID-19

Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron.

Authors: Carreño, Juan Manuel, Alshammary, Hala, Tcheou, Johnstone, Singh, Gagandeep, Raskin, Ariel J., Kawabata, Hisaaki, Sominsky, Levy A., Clark, Jordan J., Adelsberg, Daniel C., Bielak, Dominika A., Gonzalez-Reiche, Ana Silvia, Dambrauskas, Nicholas, Vigdorovich, Vladimir, Alburquerque, B., Amoako, A. A., Banu, R., Beach, K. F., Bermúdez-González, M. C., Cai, G. Y., Ceglia, I.

Source: Nature; 2/24/2022, Vol. 602 Issue 7898, p682-688, 7p

Safety and Immunogenicity Analysis of a Newcastle Disease Virus (NDV-HXP-S) Expressing the Spike Protein of SARS-CoV-2 in Sprague Dawley Rats.

Authors: Tcheou, Johnstone, Raskin, Ariel, Singh, Gagandeep, Kawabata, Hisaaki, Bielak, Dominika, Sun, Weina, González-Domínguez, Irene, Sather, D Noah, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Carreño, Juan Manuel

Source: Frontiers in Immunology; 11/18/2021, Vol. 12, p1-12, 12p

Subject Terms: NEWCASTLE disease virus, SPRAGUE Dawley rats, SARS-CoV-2, VACCINATION, ANTIBODY titer, COVID-19 vaccines, SAFETY, IMMUNE response

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