HSP90α is needed for the survival of rod photoreceptors and regulates the expression of rod PDE6 subunits

Authors: Munezero, Daniella, Aliff, Hunter, Salido, Ezequiel, Saravanan, Thamaraiselvi, Sanzhaeva, Urikhan, Guan, Tongju, Ramamurthy, Visvanathan

Source: In Journal of Biological Chemistry June 2023 299(6)

The Musashi proteins MSI1 and MSI2 are required for photoreceptor morphogenesis and vision in mice

Authors: Sundar, Jesse, Matalkah, Fatimah, Jeong, Bohye, Stoilov, Peter, Ramamurthy, Visvanathan

Source: In Journal of Biological Chemistry January-June 2021 296

Phosphomimetic Mutations Impact Huntingtin Aggregation in the Presence of a Variety of Lipid Systems

Authors: Groover, Sharon E., Beasley, Maryssa, Ramamurthy, Visvanathan, Legleiter, Justin

Source: Biochemistry. 59(49):4681-4693

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625412752&indx=1&recIds=ETOCRN625412752

Proteoglycan IMPG2 Shapes the Interphotoreceptor Matrix and Modulates Vision

Authors: Salido, Ezequiel M., Ramamurthy, Visvanathan

Source: Journal of neuroscience. 40(20):4059-4072

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623954390&indx=1&recIds=ETOCRN623954390

Loss of MPC1 reprograms retinal metabolism to impair visual function

Authors: Grenell, Allison, Wang, Yekai, Yam, Michelle, Swarup, Aditi, Dilan, Tanya L., Hauer, Allison, Linton, Jonathan D., Philp, Nancy J., Gregor, Elizabeth, Zhu, Siyan, Shi, Quan, Murphy, Joseph, Guan, Tongju, Lohner, Daniel, Kolandaivelu, Saravanan, Ramamurthy, Visvanathan, Goldberg, Andrew F. X., Hurley, James B., Dua, Jianhai

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Feb . 116(9), 3530-3535.

Access URL: https://www.jstor.org/stable/26672100

TUBB4B is essential for the cytoskeletal architecture of cochlear supporting cells and motile cilia development.

Authors: Sanzhaeva, Urikhan, Boyd-Pratt, Helen, Bender, Philip T. R., Saravanan, Thamaraiselvi, Rhodes, Scott B., Guan, Tongju, Billington, Neil, Boye, Shannon E., Cunningham, Christopher L., Anderson, Charles T., Ramamurthy, Visvanathan

Source: Communications Biology; 9/14/2024, Vol. 7 Issue 1, p1-18, 18p

Subject Terms: MIDDLE ear, OTITIS media, RETINAL degeneration, EPITHELIAL cells, CILIA & ciliary motion, INNER ear

TUBB4B is essential for the expansion of differentiating spermatogonia.

Authors: Sanzhaeva, Urikhan, Wonsettler, Natalie R., Rhodes, Scott B., Ramamurthy, Visvanathan

Source: Scientific Reports; 9/10/2024, Vol. 14 Issue 1, p1-10, 10p

Subject Terms: SPINDLE apparatus, AXONEMES, GERM cells, MALE infertility, MICROTUBULES, TUBULINS

Rhodopsin signaling mediates light-induced photoreceptor cell death in rd10 mice through a transducin-independent mechanism

Authors: Sundar, Jesse C, Munezero, Daniella, Bryan-Haring, Caitlyn, Saravanan, Thamaraiselvi, Jacques, Angelica, Ramamurthy, Visvanathan

Source: Human molecular genetics. 29(3):394-406

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100084857.0x000001&indx=1&recIds=ETOCvdc_100100084857.0x000001

The Dynamic and Complex Role of the Joubert Syndrome-Associated Ciliary Protein, ADP-Ribosylation Factor-Like GTPase 13B (ARL13B) in Photoreceptor Development and Maintenance

Authors: Dilan, Tanya, Ramamurthy, Visvanathan

Source: Advances in experimental medicine and biology. 1185:501-506

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622564098&indx=1&recIds=ETOCRN622564098

ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments

Authors: Dilan, Tanya L., Moye, Abigail R., Salido, Ezequiel M., Saravanan, Thamaraiselvi, Kolandaivelu, Saravanan, Goldberg, Andrew F. X., Ramamurthy, Visvanathan

Source: Journal of neuroscience. 39(8):1347-1364

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619178190&indx=1&recIds=ETOCRN619178190

Leber Congenital Amaurosis Linked to AIPL1: A Mouse Model Reveals Destabilization of cGMP Phosphodiesterase

Authors: Ramamurthy, Visvanathan, Niemi, Gregory A., Reh, Thomas A., Hurley, James B., Nathans, Jeremy

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Sep . 101(38), 13897-13902.

Access URL: https://www.jstor.org/stable/3373305

AIPL1, a Protein Implicated in Leber's Congenital Amaurosis, Interacts with and Aids in Processing of Farnesylated Proteins

Authors: Ramamurthy, Visvanathan, Roberts, Melanie, van den Akker, Focco, Niemi, Gregory, Reh, T. A., Hurley, James B.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Oct . 100(22), 12630-12635.

Access URL: https://www.jstor.org/stable/3148011

Excessive tubulin glutamylation leads to progressive cone-rod dystrophy and loss of outer segment integrity.

Authors: Aljammal, Rawaa, Saravanan, Thamaraiselvi, Guan, Tongju, Rhodes, Scott, Robichaux, Michael A, Ramamurthy, Visvanathan

Source: Human Molecular Genetics; 5/1/2024, Vol. 33 Issue 9, p802-817, 16p

Biochemical Analysis of a Dimerization Domain Mutation in RetGC-1 Associated with Dominant Cone-Rod Dystrophy

Authors: Tucker, Chandra L., Woodcock, Sarah C., Kelsell, Rosemary E., Ramamurthy, Visvanathan, Hunt, David M., Hurley, James B.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1999 Aug 01. 96(16), 9039-9044.

Access URL: https://www.jstor.org/stable/48269

Splice Isoforms of Phosducin-like Protein Control the Expression of Heterotrimeric G Proteins

Authors: Gao, Xueli, Sinha, Satyabrata, Belcastro, Marycharmain, Woodard, Catherine, Ramamurthy, Visvanathan, Stoilov, Peter, Sokolov, Maxim

Source: In Journal of Biological Chemistry 6 September 2013 288(36):25760-25768

Retinal Organoids derived from hiPSCs of an AIPL1-LCA Patient Maintain Cytoarchitecture despite Reduced levels of Mutant AIPL1

Authors: Lukovic, Dunja, Artero Castro, Ana, Kaya, Koray Dogan, Munezero, Daniella, Gieser, Linn, Davó-Martínez, Carlota, Corton, Marta, Cuenca, Nicolás, Swaroop, Anand, Ramamurthy, Visvanathan, Ayuso, Carmen, Erceg, Slaven

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176324637.0x000001&indx=1&recIds=ETOCvdc_100176324637.0x000001

Transducin translocation contributes to rod survival and enhances synaptic transmission from rods to rod bipolar cells

Authors: Majumder, Anurima, Pahlberg, Johan, Boyd, Kimberly K., Kerov, Vasily, Kolandaivelu, Saravanan, Ramamurthy, Visvanathan, Sampath, Alapakkam P., Artemyev, Nikolai O.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Jul . 110(30), 12468-12473.

Access URL: https://www.jstor.org/stable/42712614

Prenylation is essential for the enrichment of cone phosphodiesterase-6 (PDE6) in outer segments and efficient cone phototransduction.

Authors: Moakedi, Faezeh, Aljammal, Rawaa, Poria, Deepak, Saravanan, Thamaraiselvi, Rhodes, Scott B, Reid, Chyanne, Guan, Tongju, Kefalov, Vladimir J, Ramamurthy, Visvanathan

Source: Human Molecular Genetics; Sep2023, Vol. 32 Issue 17, p2735-2750, 16p

RAS-converting enzyme 1-mediated endoproteolysis is required for trafficking of rod phosphodiesterase 6 to photoreceptor outer segments

Authors: Christiansen, Jeffrey R., Kolandaivelu, Saravanan, Bergo, Martin O., Ramamurthy, Visvanathan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2011 May . 108(21), 8862-8866.

Access URL: https://www.jstor.org/stable/25831043

Rod Phosphodiesterase-6 (PDE6) Catalytic Subunits Restore Cone Function in a Mouse Model Lacking Cone PDE6 Catalytic Subunit

Authors: Kolandaivelu, Saravanan, Chang, Bo, Ramamurthy, Visvanathan

Source: In Journal of Biological Chemistry 23 September 2011 286(38):33252-33259