Screening antivirals with a mCherry-expressing recombinant bovine respiratory syncytial virus: a proof of concept using cyclopamine

Authors: Jenna Fix, Delphyne Descamps, Marie Galloux, Cécile Ferret, Edwige Bouguyon, Siamak Zohari, Katarina Näslund, Sara Hägglund, Ralf Altmeyer, Jean-François Valarcher, Sabine Riffault, Jean-François Eléouët

Source: Veterinary Research, Vol 54, Iss 1, Pp 1-7 (2023)

Subject Terms: Bovine respiratory syncytial virus, mCherry reverse genetics, antiviral drugs, cyclopamine, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/1297-9716

Access URL: https://doaj.org/article/57a2ce4153c94fe582863d7f7f2a2d79

Seroepidemiology of enterovirus A71 infection in prospective cohort studies of children in southern China, 2013-2018

Authors: Juan Yang, Qiaohong Liao, Kaiwei Luo, Fengfeng Liu, Yonghong Zhou, Gang Zou, Wei Huang, Shuanbao Yu, Xianglin Wei, Jiaxin Zhou, Bingbing Dai, Qi Qiu, Ralf Altmeyer, Hongan Hu, Juliette Paireau, Li Luo, Lidong Gao, Birgit Nikolay, Shixiong Hu, Weijia Xing, Peng Wu, H. Rogier van Doorn, Peter W. Horby, Peter Simmonds, Gabriel M. Leung, Benjamin J. Cowling, Simon Cauchemez, Hongjie Yu

Source: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/13d825dff5bb4fdc98370d3db1ad55c8

Evaluation of Small Molecule Combinations against Respiratory Syncytial Virus In Vitro

Authors: Yuzhen Gao, Jingjing Cao, Pan Xing, Ralf Altmeyer, Youming Zhang

Source: Molecules, Vol 26, Iss 9, p 2607 (2021)

Subject Terms: RSV, fusion inhibitors, RdRp inhibitors, combination therapy, synergistic enhancement, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/9/2607; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/ea5a047d17ac4058aa8e6f1c6fa43af0

Molecular epidemiology of human enterovirus 71 at the origin of an epidemic of fatal hand, foot and mouth disease cases in Cambodia

Authors: Veasna Duong, Channa Mey, Marc Eloit, Huachen Zhu, Lucie Danet, Zhong Huang, Gang Zou, Arnaud Tarantola, Justine Cheval, Philippe Perot, Denis Laurent, Beat Richner, Santy Ky, Sothy Heng, Sok Touch, Ly Sovann, Rogier van Doorn, Thanh Tan Tran, Jeremy J Farrar, David E Wentworth, Suman R Das, Timothy B Stockwell, Jean-Claude Manuguerra, Francis Delpeyroux, Yi Guan, Ralf Altmeyer, Philippe Buchy

Source: Emerging Microbes and Infections, Vol 5, Iss 1, Pp 1-9 (2016)

Subject Terms: Cambodia, epidemic, hand foot and mouth disease, human enterovirus 71, severe disease, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/e6c5363df12c4990951c6ee105807955

Repurposing of approved drugs from the human pharmacopoeia to target Wolbachia endosymbionts of onchocerciasis and lymphatic filariasis

Authors: Kelly L. Johnston, Louise Ford, Indira Umareddy, Simon Townson, Sabine Specht, Kenneth Pfarr, Achim Hoerauf, Ralf Altmeyer, Mark J. Taylor

Source: International Journal for Parasitology: Drugs and Drug Resistance, Vol 4, Iss 3, Pp 278-286 (2014)

Subject Terms: Wolbachia, Filariasis, Pharmacopoeia, Drug discovery, Library screening, Anti-Wolbachia Consortium (A·WOL), Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211320714000244; https://doaj.org/toc/2211-3207

Access URL: https://doaj.org/article/191f48b845eb4d168c6bc523ea0cd3ab

The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection—suramin inhibits EV71 infection in vitro and in vivo

Authors: Peijun Ren, Gang Zou, Benjamin Bailly, Shanshan Xu, Mei Zeng, Xinsheng Chen, Liang Shen, Ying Zhang, Patrice Guillon, Fernando Arenzana-Seisdedos, Philippe Buchy, Jian Li, Mark von Itzstein, Qihan Li, Ralf Altmeyer

Source: Emerging Microbes and Infections, Vol 3, Iss 1, Pp 1-9 (2014)

Subject Terms: anti-viral, drug discovery, enterovirus 71, hand, foot and mouth disease, suramin, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/570bccbd09e9427a9101bff9c6319b4b

Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication

Authors: Christopher M Owens, Christina Mawhinney, Jill M Grenier, Ralf Altmeyer, Margaret S Lee, Alexis A Borisy, Joseph Lehár, Lisa M Johansen

Source: Molecular Systems Biology, Vol 6, Iss 1, Pp 1-13 (2010)

Subject Terms: chemical genetics, combinations and synergy, hepatitis C, replicon, sterol biosynthesis, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/b4b9b49657b3440dabf153426b420ffc

Correction: A Dominant EV71-Specific CD4+ T Cell Epitope Is Highly Conserved among Human Enteroviruses.

Authors: Ruicheng Wei, Chunfu Yang, Mei Zeng, Frances Terry, Kai Zhu, Chunhui Yang, Ralf Altmeyer, William Martin, Anne S. De Groot, Qibin Leng

Source: PLoS ONE, Vol 9, Iss 1 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3891554; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/dc04638fc72c4984b45e4a284c199e14

The cytokine and chemokine profiles in patients with hand, foot and mouth disease of different severities in Shanghai, China, 2010.

Authors: Mei Zeng, Xiaoyan Zheng, Ruicheng Wei, Na Zhang, Kai Zhu, Bin Xu, Chun-Hui Yang, Chun-Fu Yang, Chaoyang Deng, Dongbo Pu, Xiaohong Wang, Ralf Altmeyer, Qibin Leng

Source: PLoS Neglected Tropical Diseases, Vol 7, Iss 12, p e2599 (2013)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3868519?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/e1836a4be6e541f08fda820a607dd0ea

A dominant EV71-specific CD4+ T cell epitope is highly conserved among human enteroviruses.

Authors: Ruicheng Wei, Chunfu Yang, Mei Zeng, Frances Terry, Kai Zhu, Chunhui Yang, Ralf Altmeyer, William Martin, Anne S De Groot, Qibin Leng

Source: PLoS ONE, Vol 7, Iss 12, p e51957 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23251663/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0ab7a891667943df897793627a69b871

Cleavage of the SARS coronavirus spike glycoprotein by airway proteases enhances virus entry into human bronchial epithelial cells in vitro.

Authors: Yiu-Wing Kam, Yuushi Okumura, Hiroshi Kido, Lisa F P Ng, Roberto Bruzzone, Ralf Altmeyer

Source: PLoS ONE, Vol 4, Iss 11, p e7870 (2009)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2773421?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cd6fcbc5d0ad4a268a6059048e34722d

Children of rural-to-urban migrant workers in China are at a higher risk of contracting severe hand, foot and mouth disease and EV71 infection: a hospital-based study.

Authors: Mei Zeng, Dongbo Pu, Xiaowei Mo, Chaomin Zhu, Sitang Gong, Yi Xu, Guangyu Lin, Beiyan Wu, Suli He, Xiaoyang Jiao, Xiangshi Wang, Xiaohong Wang, Qianqian Zhu, Ralf Altmeyer

Source: Emerging Microbes & Infections; 2013, Vol. 2 Issue 10, p1-6, 6p

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