Inhibition of oxidative stress delays senescence and augments functional capacity of endothelial progenitor cells

Authors: Reskiawan A. Kadir, Rais, Alwjwaj, Mansour, Ahmad Othman, Othman, Rakkar, Kamini, Sprigg, Nikola, Bath, Philip M., Bayraktutan, Ulvi

Source: In Brain Research 15 July 2022 1787

Analysis of endothelial progenitor cell subtypes as clinical biomarkers for elderly patients with ischaemic stroke.

Authors: Kadir, Rais Reskiawan A.¹ (AUTHOR), Rakkar, Kamini¹ (AUTHOR), Othman, Othman A.¹ (AUTHOR), Sprigg, Nikola¹ (AUTHOR), Bath, Philip M.¹ (AUTHOR), Bayraktutan, Ulvi^1,2 (AUTHOR) ulvi.bayraktutan@nottingham.ac.uk

Source: Scientific Reports. 12/9/2023, Vol. 13 Issue 1, p1-9. 9p.

Subject Terms: *ISCHEMIC stroke, *OLDER patients, *OXIDANT status, *ENDOTHELIAL cells, *STROKE patients, *STROKE, *IMMUNOSENESCENCE, *PROGENITOR cells, *GLYCOCALYX

Company/Entity: NATIONAL Institutes of Health (U.S.)

Comorbidities and Angiogenic Regulators Affect Endothelial Progenitor Cell Subtype Numbers in a Healthy Volunteer Control Group.

Authors: Rakkar, Kamini¹ (AUTHOR), Kadir, Rais Reskiawan A.² (AUTHOR), Othman, Othman A.³ (AUTHOR), Sprigg, Nikola^4,5 (AUTHOR), Bath, Philip M.^4,5 (AUTHOR), Bayraktutan, Ulvi⁵ (AUTHOR) ulvi.bayraktutan@nottingham.ac.uk

Source: Stem Cell Reviews & Reports. Nov2024, Vol. 20 Issue 8, p2336-2344. 9p.

Subject Terms: *ENDOTHELIAL growth factors, *GRANULOCYTE-colony stimulating factor, *PROGENITOR cells, *STEM cells, *ENDOTHELIAL cells

Increases in intracellular calcium perturb blood–brain barrier via protein kinase C-alpha and apoptosis

Authors: Rakkar, Kamini, Bayraktutan, Ulvi

Source: In BBA - Molecular Basis of Disease January 2016 1862(1):56-71

Mepolizumab-induced Changes in Nasal Methylome and Transcriptome to Predict Response in Asthma.

Authors: Rakkar, Kamini, Pang, Yik L., Rajasekar, Poojitha, Portelli, Michael A., Hall, Robert J., Clifford, Rachel L., Shaw, Dominick, Sayers, Ian

Source: American Journal of Respiratory & Critical Care Medicine; 5/15/2024, Vol. 209 Issue 10, p1268-1272, 5p

Subject Terms: ASTHMA, MEDICAL personnel, TRANSCRIPTOMES, GENE expression

Inhibition of TNF-α protects in vitro brain barrier from ischaemic damage

Authors: Abdullah, Zuraidah, Rakkar, Kamini, Bath, Philip M.W., Bayraktutan, Ulvi

Source: In Molecular and Cellular Neuroscience November 2015 69:65-79

Evaluation of Endothelial Progenitor Cell Characteristics as Clinical Biomarkers for Elderly Patients with Ischaemic Stroke.

Authors: Rakkar, Kamini¹ (AUTHOR), Othman, Othman Ahmad¹ (AUTHOR), Sprigg, Nikola¹ (AUTHOR), Bath, Philip M.¹ (AUTHOR), Bayraktutan, Ulvi¹ (AUTHOR) ulvi.bayraktutan@nottingham.ac.uk

Source: Stem Cell Reviews & Reports. Aug2023, Vol. 19 Issue 6, p1856-1869. 14p.

Subject Terms: *ISCHEMIC stroke, *PROGENITOR cells, *ENDOTHELIAL cells, *OLDER patients, *STROKE patients, *IMMUNOSENESCENCE, *GLYCOCALYX

Outgrowth Endothelial Cell Conditioned Medium Negates TNF-α-Evoked Cerebral Barrier Damage: A Reverse Translational Research to Explore Mechanisms.

Authors: Kadir, Rais Reskiawan A., Alwjwaj, Mansour, Rakkar, Kamini, Othman, Othman Ahmad, Sprigg, Nikola, Bath, Philip M., Bayraktutan, Ulvi

Source: Stem Cell Reviews & Reports; Feb2023, Vol. 19 Issue 2, p503-515, 13p

Subject Terms: BLOOD-brain barrier, ISCHEMIC stroke, TRANSLATIONAL research, STROKE, EXTRACELLULAR matrix, EARLY death, ENDOTHELIAL cells, TUMOR necrosis factors

Elevated plasminogen activators are associated with hematoma progression in spontaneous intracerebral hemorrhage

Authors: Law, Zhe Kang, Desborough, Michael, Rakkar, Kamini, Bath, Philip M., Bayraktutan, Ulvi, Sprigg, Nikola

Source: In Brain Hemorrhages March 2020 1(1):75-79

Attenuation of urokinase activity during experimental ischaemia protects the cerebral barrier from damage through regulation of matrix metalloproteinase-2 and NAD(P)H oxidase.

Authors: Rakkar, Kamini¹, Srivastava, Kirtiman¹, Bayraktutan, Ulvi¹

Source: European Journal of Neuroscience. Jun2014, Vol. 39 Issue 12, p2119-2128. 10p.

Subject Terms: *UROKINASE, *CEREBRAL ischemia, *BLOOD-brain barrier, *MATRIX metalloproteinases, *NADPH oxidase, *PLASMINOGEN activators, *ENDOTHELIAL cells