Incompletely closed HIV-1CH040 envelope glycoproteins resist broadly neutralizing antibodies while mediating efficient HIV-1 entry

Authors: Durgadevi Parthasarathy, Stephanie Pickthorn, Shamim Ahmed, Dmitry Mazurov, Jeffy Jeffy, Rajni Kant Shukla, Amit Sharma, Alon Herschhorn

Source: npj Viruses, Vol 3, Iss 1, Pp 1-13 (2025)

Subject Terms: Infectious and parasitic diseases, RC109-216, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2948-1767

Access URL: https://doaj.org/article/83dc478de8f44a1593006f3393135816

Simian immunodeficiency virus and storage buffer: Field-friendly preservation methods for RNA viral detection in primate feces

Authors: Tessa H. C. Wilde, Rajni Kant Shukla, Christopher Madden, Yael Vodovotz, Amit Sharma, W. Scott McGraw, Vanessa L. Hale

Source: mSphere, Vol 8, Iss 6 (2023)

Subject Terms: simian immunodeficiency virus, RNA virus, preservation methods, Cercocebus atys, non-invasive, non-human primate, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/3aab7542436142c7b4d3fa40c5f5bdb3

Innate adaptive immune cell dynamics in tonsillar tissues during chronic SIV infection

Authors: Rajni Kant Shukla, Manuja Gunasena, Nicole Reinhold-Larsson, Michael Duncan, Amila Hatharasinghe, Samuel Cray, Krishanthi Weragalaarachchi, Dhanuja Kasturiratna, Thorsten Demberg, Namal P. M. Liyanage

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: SIV, tonsils, NK, T cells, monocytes, NKB cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1201677/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a3e204ae6baa4c8981d16db34a462aae

Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.

Authors: Naresh Kumar, Matthew J Pestrak, Qian Wu, Omar Santiagonunez Ahumada, Sheri Dellos-Nolan, Noushin Saljoughian, Rajni Kant Shukla, Cortney F Mitchem, Prabhakara R Nagareddy, Latha P Ganesan, Lafuse P William, Daniel J Wozniak, Murugesan V S Rajaram

Source: PLoS Pathogens, Vol 19, Iss 8, p e1011573 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011573&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/52fbcfa4bf47448c99082917222fe255

Evaluation of early innate and adaptive immune responses to the TB vaccine Mycobacterium bovis BCG and vaccine candidate BCGΔBCG1419c

Authors: Manuja Gunasena, Rajni Kant Shukla, Naiquan Yao, Oscar Rosas Mejia, Michael D. Powell, Kenneth J. Oestreich, Michel de Jesús Aceves-Sánchez, Mario Alberto Flores-Valdez, Namal P. M. Liyanage, Richard T. Robinson

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/39d7006d20634ee79c2e206a6e612978

cPLA2 blockade attenuates S100A7-mediated breast tumorigenicity by inhibiting the immunosuppressive tumor microenvironment

Authors: Sanjay Mishra, Manish Charan, Rajni Kant Shukla, Pranay Agarwal, Swati Misri, Ajeet K. Verma, Dinesh K. Ahirwar, Jalal Siddiqui, Kirti Kaul, Neety Sahu, Kunj Vyas, Ayush Arpit Garg, Anum Khan, Wayne O. Miles, Jonathan W. Song, Nidhi Bhutani, Ramesh K. Ganju

Source: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)

Subject Terms: Metastasis, Breast cancer, S100A7, cPLA2, PGE2, Tumor microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/828bc8c8787a4e5b8a20e7cf1c6fef35

CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells

Authors: Shihyoung Kim, Rajni Kant Shukla, Hannah Yu, Alice Baek, Sophie G. Cressman, Sarah Golconda, Ga-Eun Lee, Hyewon Choi, John C. Reneau, Zhirui Wang, Christene A. Huang, Namal P. M. Liyanage, Sanggu Kim

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: CD3e immunotoxin, tissue-resident T cells, regulatory T cells, tolerance induction, T-cell lymphoma therapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1011190/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3b840e0ad0204180b5823337e4db9f75

Tissue-localized immune responses in people with cystic fibrosis and respiratory nontuberculous mycobacteria infection

Authors: Don Hayes Jr., Rajni Kant Shukla, Yizi Cheng, Emrah Gecili, Marlena R. Merling, Rhonda D. Szczesniak, Assem G. Ziady, Jason C. Woods, Luanne Hall-Stoodley, Namal P.M. Liyanage, Richard T. Robinson

Source: JCI Insight, Vol 7, Iss 12 (2022)

Subject Terms: Infectious disease, Pulmonology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/4eb2e4ec73f04f1db4ca8742c6cfb12c

Conformation of HIV-1 Envelope Governs Rhesus CD4 Usage and Simian-Human Immunodeficiency Virus Replication

Authors: Geraldine Vilmen, Anna C. Smith, Hector Cervera Benet, Rajni Kant Shukla, Ross C. Larue, Alon Herschhorn, Amit Sharma

Source: mBio, Vol 13, Iss 1 (2022)

Subject Terms: HIV-1 envelope, CD4, rhesus macaque, SHIV, conformation, viral entry, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/11b2056b21014eb1a17db163257a007e

Innate Immune Responses to Highly Pathogenic Coronaviruses and Other Significant Respiratory Viral Infections

Authors: Hanaa Ahmed-Hassan, Brianna Sisson, Rajni Kant Shukla, Yasasvi Wijewantha, Nicholas T. Funderburg, Zihai Li, Don Hayes, Thorsten Demberg, Namal P. M. Liyanage

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: SARS-CoV-2, COVID-19, innate immune responses, Coronavirus (CoV), Coronavirus (2019-nCoV) outbreak, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01979/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/bc1e5d1f06804f14b5d7b3f0e2c1b48c

Comparison of CD3e Antibody and CD3e-sZAP Immunotoxin Treatment in Mice Identifies sZAP as the Main Driver of Vascular Leakage

Authors: Shihyoung Kim, Rajni Kant Shukla, Eunsoo Kim, Sophie G. Cressman, Hannah Yu, Alice Baek, Hyewon Choi, Alan Kim, Amit Sharma, Zhirui Wang, Christene A. Huang, John C. Reneau, Prosper N. Boyaka, Namal P. M. Liyanage, Sanggu Kim

Source: Biomedicines, Vol 10, Iss 6, p 1221 (2022)

Subject Terms: CD3e monoclonal antibody, CD3e immunotoxin, T-cell depletion, saporin, saporin–streptavidin (sZAP), vascular leakage syndrome, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/6/1221; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/af538e4d4c3c4a8294f7418f482deb4b

Association of Cytokine Gene Polymorphisms in Patients with Chronic Obstructive Pulmonary Disease

Authors: Rajni Kant Shukla, Surya Kant, Sandeep Bhattacharya, Balraj Mittal

Source: Oman Medical Journal, Vol 27, Iss 4, Pp 285-290 (2012)

Subject Terms: Chronic obstructive pulmonary disease (COPD), Interleukine-1 (IL-1), Tumor necrosis factor - alpha (TNF- 308)., Medicine

File Description: electronic resource

Relation: http://www.omjournal.org/fultext_PDF.aspx?DetailsID=262&type=fultext; https://doaj.org/toc/1999-768X; https://doaj.org/toc/2070-5204

Access URL: https://doaj.org/article/148fcd15c2614a20a42b82dcb458e709

Comparative study of GST polymorphism in relation to age in COPD and lung cancer.

Alternate Title: KOAH ve akciğer kanserinde yaşla ilişkili olarak GST polimorfizmi karşılaştırmalı çalışma. (Turkish)

Authors: Rajni KANT SHUKLA, KANT, Surya, MITTAL, Balraj, BHATTACHARYA, Sandeep

Source: Tuberculosis & Thorax / Tuberkoloz ve Toraks; 2013, Vol. 61 Issue 4, p275-282, 8p

Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses.

Authors: Taishi Onodera¹, Kana Hashi¹, Rajni Kant Shukla¹, Motohiro Miki^2,3, Reiko Takai-Todaka², Akira Fujimoto², Masayuki Kuraoka⁴, Tatsuya Miyoshi⁵, Kazuo Kobayashi⁶, Hideki Hasegawa⁷, Manabu Ato⁷, Kelsoe, Garnett⁴, Kazuhiko Katayama², Yoshimasa Takahashi¹ ytakahas@niid.go.jp

Source: Journal of Immunology. 12/15/2019, Vol. 203 Issue 12, p3282-3292. 11p.

Subject Terms: *VIRUS-like particles, *VACCINES, *EPITOPES