Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions

Authors: Gabele, Anna ^{1, 2, 13}, Sprang, Maximilian ^{3, 13}, Cihan, Mert ³, Welzel, Mareen ⁴, Nurbekova, Assel ¹, Romaniuk, Karolina ¹, Dietzen, Sarah ^{1, 2, 5}, Klein, Matthias ^{1, 2}, Bündgen, Georg ¹, Emelianov, Maxim ¹, Harms, Gregory ^{2, 6}, Rajalingam, Krishnaraj ^{2, 6}, Ziesmann, Tanja ¹, Pape, Katrin ⁷, Wasser, Beatrice ⁷, Gomez-Zepeda, David ^{8, 9}, Braband, Kathrin ¹, Delacher, Michael ^{1, 2}, Lemmermann, Niels ^{2, 10, 11}, Bittner, Stefan ^{2, 7, 12}, Andrade-Navarro, Miguel A. ³, Tenzer, Stefan ^{1, 2, 8, 9}, Luck, Katja ⁴, Bopp, Tobias ^{1, 2, ∗}, Distler, Ute ^{1, 2, 14, ∗∗}

Source: In Cell Reports 25 March 2025 44(3)

Proteome landscape and interactome of voltage-gated potassium channel 1.6 (Kv1.6) of the murine ophthalmic artery and neuroretina

Authors: Perumal, Natarajan, Yurugi, Hajime, Dahm, Katrin, Rajalingam, Krishnaraj, Grus, Franz H., Pfeiffer, Norbert, Manicam, Caroline

Source: In International Journal of Biological Macromolecules February 2024 257 Part 1

Development of fluorizoline analogues as prohibitin ligands that modulate C-RAF signaling, p21 expression and melanogenesis

Authors: Chouha, Nora, Abou-Hamdan, Hussein, Yurugi, Hajime, Yoshii, Riku, Ii, Hiromi, Najem, Ahmad, Ghanem, Ghanem E., Nakata, Susumu, Rajalingam, Krishnaraj, Peng, Yu, Wang, Dong, Nebigil, Canan G., Désaubry, Laurent

Source: In European Journal of Medicinal Chemistry 15 November 2022 242

SIK2 orchestrates actin-dependent host response upon Salmonella infection

Authors: Hahn, Marcel, Covarrubias-Pinto, Adriana, Herhaus, Lina, Satpathy, Shankha, Klann, Kevin, Boyle, Keith B., Münch, Christian, Rajalingam, Krishnaraj, Randow, Felix, Choudhary, Chunaram, Dikic, Ivan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 May 01. 118(19), 1-10.

Access URL: https://www.jstor.org/stable/27040491

Cilium induction triggers differentiation of glioma stem cells

Authors: Goranci-Buzhala, Gladiola, Mariappan, Aruljothi, Ricci-Vitiani, Lucia, Josipovic, Natasa, Pacioni, Simone, Gottardo, Marco, Ptok, Johannes, Schaal, Heiner, Callaini, Giuliano, Rajalingam, Krishnaraj, Dynlacht, Brian, Hadian, Kamyar, Papantonis, Argyris, Pallini, Roberto, Gopalakrishnan, Jay

Source: In Cell Reports 7 September 2021 36(10)

Famotidine inhibits toll-like receptor 3-mediated inflammatory signaling in SARS-CoV-2 infection

Authors: Mukherjee, Rukmini, Bhattacharya, Anshu, Bojkova, Denisa, Mehdipour, Ahmad Reza, Shin, Donghyuk, Khan, Khadija Shahed, Hei-Yin Cheung, Hayley, Wong, Kam-Bo, Ng, Wai-Lung, Cinatl, Jindrich, Geurink, Paul P., van der Heden van Noort, Gerbrand J., Rajalingam, Krishnaraj, Ciesek, Sandra, Hummer, Gerhard, Dikic, Ivan

Source: In Journal of Biological Chemistry August 2021 297(2)

The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection

Authors: Imre, Gergely, Krähling, Verena, Eichler, Madeleine, Trautmann, Sandra, Ferreirós, Nerea, Aman, M. Javad, Kashanchi, Fatah, Rajalingam, Krishnaraj, Pöhlmann, Stefan, Becker, Stephan, Meyer zu Heringdorf, Dagmar, Pfeilschifter, Josef

Source: In iScience 23 April 2021 24(4)

Druggable genome and precision medicine in cancer: current challenges

Authors: Dupont, Camille Amandine, Riegel, Kristina, Pompaiah, Malvika, Juhl, Hartmut, Rajalingam, Krishnaraj

Source: FEBS journal. 288(21):6142-6158

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134552403.0x000001&indx=1&recIds=ETOCvdc_100134552403.0x000001

Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids

Authors: Wiechmann, Svenja, Maisonneuve, Pierre, Grebbin, Britta M., Hoffmeister, Meike, Kaulich, Manuel, Clevers, Hans, Rajalingam, Krishnaraj, Kurinov, Igor, Farin, Henner F., Sicheri, Frank, Ernst, Andreas

Source: In Journal of Biological Chemistry 3 April 2020 295(14):4526-4540

ANKRD26-RET - A novel gene fusion involving RET in papillary thyroid carcinoma

Authors: Staubitz, Julia Isabelle, Musholt, Thomas Johannes, Schad, Arno, Springer, Erik, Lang, Hauke, Rajalingam, Krishnaraj, Roth, Wilfried, Hartmann, Nils

Source: In Cancer Genetics October 2019 238:10-17

The non-linearity of RAF-MEK signaling in dendritic cells

Authors: Riegel, Kristina, Rajalingam, Krishnaraj

Source: Cell cycle. 19(18):2249-2259

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131875576.0x000001&indx=1&recIds=ETOCvdc_100131875576.0x000001

Novel rearrangements involving the RET gene in papillary thyroid carcinoma

Authors: Staubitz, Julia Isabelle, Schad, Arno, Springer, Erik, Rajalingam, Krishnaraj, Lang, Hauke, Roth, Wilfried, Hartmann, Nils, Musholt, Thomas Johannes

Source: In Cancer Genetics January 2019 230:13-20

The non-enzymatic RAS effector RASSF7 inhibits oncogenic c-Myc function

Authors: Kumaraswamy, Anbarasu, Mamidi, Anitha, Desai, Pavitra, Sivagnanam, Ananthi, Perumalsamy, Lakshmi Revathi, Ramakrishnan, Chandrasekaran, Gromiha, Michael, Rajalingam, Krishnaraj, Mahalingam, Sundarasamy

Source: In Journal of Biological Chemistry 5 October 2018 293(40):15691-15705

E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases

Alternate Title: E4BP4 modulates the function of RASSF8 (English)

Authors: Karthik, Isai Pratha, Desai, Pavitra, Sukumar, Sudarkodi, Dimitrijevic, Aleksandra, Rajalingam, Krishnaraj, Mahalingam, Sundarasamy

Source: In Journal of Biological Chemistry 13 April 2018 293(15):5624-5635

Integrate and conquer: pan-cancer proteogenomics uncovers cancer vulnerabilities and therapeutic opportunities.

Authors: Chakraborty, Debomita, Romero, Rossana, Rajalingam, Krishnaraj

Source: Signal Transduction & Targeted Therapy; 10/16/2024, Vol. 9 Issue 1, p1-3, 3p

PRG-1 Regulates Synaptic Plasticity via Intracellular PP2A/β1-Integrin Signaling

Authors: Liu, Xingfeng, Huai, Jisen, Endle, Heiko, Schlüter, Leslie, Fan, Wei, Li, Yunbo, Richers, Sebastian, Yurugi, Hajime, Rajalingam, Krishnaraj, Ji, Haichao, Cheng, Hong, Rister, Benjamin, Horta, Guilherme, Baumgart, Jan, Berger, Hendrik, Laube, Gregor, Schmitt, Ulrich, Schmeisser, Michael J., Boeckers, Tobias M., Tenzer, Stefan, Vlachos, Andreas, Deller, Thomas, Nitsch, Robert, Vogt, Johannes

Source: In Developmental Cell 8 August 2016 38(3):275-290

IAPs and cell migration

Authors: Dubrez, Laurence, Rajalingam, Krishnaraj

Source: In Seminars in Cell and Developmental Biology March 2015 39:124-131

Apoptosis inhibitor 5 is an endogenous inhibitor of caspase‐2

Authors: Imre, Gergely, Berthelet, Jean, Heering, Jan, Kehrloesser, Sebastian, Melzer, Inga Maria, Lee, Byung Il, Thiede, Bernd, Dötsch, Volker, Rajalingam, Krishnaraj

Source: EMBO reports. 18(5):733-744

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095073727.0x000001&indx=1&recIds=ETOCvdc_100095073727.0x000001

PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection

Authors: McEwan, David G., Richter, Benjamin, Claudi, Beatrice, Wigge, Christoph, Wild, Philipp, Farhan, Hesso, McGourty, Kieran, Coxon, Fraser P., Franz-Wachtel, Mirita, Perdu, Bram, Akutsu, Masato, Habermann, Anja, Kirchof, Anja, Helfrich, Miep H., Odgren, Paul R., Van Hul, Wim, Frangakis, Achilleas S., Rajalingam, Krishnaraj, Macek, Boris, Holden, David W., Bumann, Dirk, Dikic, Ivan

Source: In Cell Host & Microbe 14 January 2015 17(1):58-71

Endo-PDI is required for TNFα-induced angiogenesis

Authors: Camargo, Livia de Lucca, Babelova, Andrea, Mieth, Anja, Weigert, Andreas, Mooz, Juliane, Rajalingam, Krishnaraj, Heide, Heinrich, Wittig, Ilka, Lopes, Lucia Rossetti, Brandes, Ralf P.

Source: In Free Radical Biology and Medicine December 2013 65:1398-1407