Case report: Tracing in parallel the salivary and gut microbiota profiles to assist Larotrectinib anticancer treatment for NTRK fusion–positive glioblastoma.

Authors: Turco, Luigia, Della Monica, Rosa, Giordano, Pasqualina, Cuomo, Mariella, Biazzo, Manuele, Mateu, Baptiste, Di Liello, Raimondo, Daniele, Bruno, Normanno, Nicola, De Luca, Antonella, Rachiglio, Anna Maria, Chiaramonte, Carmela, Giugliano, Francesca Maria, Chiariotti, Lorenzo, Catapano, Giuseppe, Coretti, Lorena, Lembo, Francesca

Source: Frontiers in Oncology; 2024, p1-8, 8p

Subject Terms: BACTEROIDES fragilis, GUT microbiome, GLIOBLASTOMA multiforme, ENTEROCOCCUS faecium, BACTERIAL communities

Transient 'NeoBRAF wild type' state in a patient with BRAF^V600E mutant metastatic colorectal cancer.

Authors: Cardone, Claudia, Facchini, Sergio, de Stefano, Alfonso, Rachiglio, Anna Maria, Avallone, Antonio

Source: Cytopathology; Nov2024, Vol. 35 Issue 6, p671-673, 3p

Subject Terms: SOMATIC mutation, TREATMENT effectiveness, CELL-free DNA, SYMPTOM burden, ADJUVANT chemotherapy, LUNGS

The role of circulating free DNA in the management of NSCLC

Authors: Esposito Abate, Riziero, Pasquale, Raffaella, Fenizia, Francesca, Rachiglio, Anna Maria, Roma, Cristin, Bergantino, Francesca, Forgione, Laura, Lambiase, Matilde, Sacco, Alessandra, Piccirillo, Maria Carmela, Morabito, Alessandro, Normanno, Nicola

Source: Expert review of anticancer therapy. 19(1):19-28

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100098218637.0x000001&indx=1&recIds=ETOCvdc_100098218637.0x000001

The Impact of Inadequate Exposure to Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors on the Development of Resistance in Non-Small-Cell Lung Cancer Cells.

Authors: Frezzetti, Daniela, Caridi, Vincenza, Marra, Laura, Camerlingo, Rosa, D'Alessio, Amelia, Russo, Francesco, Dotolo, Serena, Rachiglio, Anna Maria, Esposito Abate, Riziero, Gallo, Marianna, Maiello, Monica Rosaria, Morabito, Alessandro, Normanno, Nicola, De Luca, Antonella

Source: International Journal of Molecular Sciences; May2024, Vol. 25 Issue 9, p4844, 17p

Subject Terms: NON-small-cell lung carcinoma, EPIDERMAL growth factor receptors, EPIDERMAL growth factor, KINASE inhibitors, TRANSFORMING growth factors, CANCER cells

Clinical outcome and molecular characterisation of chemorefractory metastatic colorectal cancer patients with long-term efficacy of regorafenib treatment

Authors: Martinelli, Erika, Sforza, Vincenzo, Cardone, Claudia, Capasso, Anna, Nappi, Anna, Martini, Giulia, Napolitano, Stefania, Rachiglio, Anna Maria, Normanno, Nicola, Cappabianca, Salvatore, Reginelli, Alfonso, Bisceglie, Maurizio Di, Latiano, Tiziana Pia, Maiello, Evaristo, Orditura, Michele, De Vita, Fernando, Morgillo, Floriana, Ciardiello, Fortunato, Troiani, Teresa

Source: In ESMO Open 2017 2(3)

SARS-CoV-2 complete genome sequencing from the Italian Campania region using a highly automated next generation sequencing system.

Authors: Rachiglio, Anna Maria¹ (AUTHOR), De Sabato, Luca² (AUTHOR), Roma, Cristin¹ (AUTHOR), Cennamo, Michele³ (AUTHOR), Fiorenza, Mariano³ (AUTHOR), Terracciano, Daniela³ (AUTHOR), Pasquale, Raffaella¹ (AUTHOR), Bergantino, Francesca¹ (AUTHOR), Cavalcanti, Ernesta⁴ (AUTHOR), Botti, Gerardo⁵ (AUTHOR), Vaccari, Gabriele² (AUTHOR), Portella, Giuseppe³ (AUTHOR), Normanno, Nicola¹ (AUTHOR) n.normanno@istitutotumori.na.it

Source: Journal of Translational Medicine. 6/5/2021, Vol. 19 Issue 1, p1-10. 10p.

Subject Terms: *SARS-CoV-2, *NUCLEOTIDE sequencing, *VIRAL genomes, *COVID-19, *VACCINE effectiveness, *EXOMES, *GENE libraries

Geographic Terms: CAMPANIA (Italy)

BRAF V600E mutation in metastatic colorectal cancer: Methods of detection and correlation with clinical and pathologic features

Authors: Roma, Cristin, Rachiglio, Anna Maria, Pasquale, Raffaella, Fenizia, Francesca, Iannaccone, Alessia, Tatangelo, Fabiana, Antinolfi, Giuseppe, Parrella, Paola, Graziano, Paolo, Sabatino, Lina, Colantuoni, Vittorio, Botti, Gerardo, Maiello, Evaristo, Normanno, Nicola

Source: Cancer biology & therapy. 17(8):840-848

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100035108939.0x000001&indx=1&recIds=ETOCvdc_100035108939.0x000001

Assessment of high-sensitive methods for the detection of EGFR mutations in circulating free tumor DNA from NSCLC patients

Authors: Pasquale, Raffaella, Fenizia, Francesca, Esposito Abate, Riziero, Sacco, Alessandra, Esposito, Claudia, Forgione, Laura, Rachiglio, Anna Maria, Bevilacqua, Simona, Montanino, Agnese, Franco, Renato, Rocco, Gaetano, Botti, Gerardo, Denis, Marc G, Morabito, Alessandro, De Luca, Antonella, Normanno, Nicola

Source: Pharmacogenomics. 16(10):1135-1148

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125689807.0x000001&indx=1&recIds=ETOCvdc_100125689807.0x000001

Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol

Authors: Ottaiano, Alessandro, Scala, Stefania, Normanno, Nicola, Napolitano, Maria, Capozzi, Monica, Rachiglio, Anna Maria, Roma, Cristin, Trotta, Anna Maria, D'Alterio, Crescenzo, Portella, Luigi, Romano, Carmela, Cassata, Antonino, Casaretti, Rossana, Silvestro, Lucrezia, Nappi, Anna, Tafuto, Salvatore, Avallone, Antonio, De Stefano, Alfonso, Tamburini, Mario, Picone, Carmine, Petrillo, Antonella, Izzo, Francesco, Palaia, Raffaele, Albino, Vittorio, Amore, Alfonso, Belli, Andrea, Pace, Ugo, Di Marzo, Massimiliano, Chiodini, Paolo, Botti, Gerardo, De Feo, Gianfranco, Delrio, Paolo, Nasti, Guglielmo

Source: BMC cancer. 19(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127171758.0x000001&indx=1&recIds=ETOCvdc_100127171758.0x000001

The S492R EGFR ectodomain mutation is never detected in KRAS wild-type colorectal carcinoma before exposure to EGFR monoclonal antibodies

Authors: Esposito, Claudia, Rachiglio, Anna Maria, La Porta, Maria Libera, Sacco, Alessandra, Roma, Cristin, Iannaccone, Alessia, Tatangelo, Fabiana, Forgione, Laura, Pasquale, Raffaella, Barbaro, Americo, Botti, Gerardo, Ciardiello, Fortunato, Normanno, Nicola

Source: Cancer biology & therapy. 14(12):1143-1146

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050659211.0x000001&indx=1&recIds=ETOCvdc_100050659211.0x000001

Detection of KRAS mutations in colorectal carcinoma patients with an integrated PCR/sequencing and real-time PCR approach

Authors: Carotenuto, Pietro, Roma, Cristin, Rachiglio, Anna Maria, Tatangelo, Fabiana, Pinto, Carmine, Ciardiello, Fortunato, Nappi, Oscar, Iaffaioli, Vincenzo, Botti, Gerardo, Normanno, Nicola

Source: Pharmacogenomics. 11(8):1169-1179

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121255592.0x000001&indx=1&recIds=ETOCvdc_100121255592.0x000001

Simultaneous detection of lung fusions using a multiplex RT-PCR next generation sequencing-based approach: a multi-institutional research study

Authors: Vaughn, Cecily P., Costa, José Luis, Feilotter, Harriet E., Petraroli, Rosella, Bagai, Varun, Rachiglio, Anna Maria, Marino, Federica Zito, Tops, Bastiaan, Kurth, Henriette M., Sakai, Kazuko, Mafficini, Andrea, Bastien, Roy R. L., Reiman, Anne, Le Corre, Delphine, Boag, Alexander, Crocker, Susan, Bihl, Michel, Hirschmann, Astrid, Scarpa, Aldo, Machado, José Carlos, Blons, Hélène, Sheils, Orla, Bramlett, Kelli, Ligtenberg, Marjolijn J. L., Cree, Ian A., Normanno, Nicola, Nishio, Kazuto, Laurent-Puig, Pierre

Source: BMC cancer. 18(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127177842.0x000001&indx=1&recIds=ETOCvdc_100127177842.0x000001

Chapter 32 - Circulating Tumor Cells and ctDNA in NSCLC: A Role for Treatment Decision

Authors: Fenizia, Francesca, Rachiglio, Anna Maria, Iannaccone, Alessia, Chicchinelli, Nicoletta, Normanno, Nicola

Source: In Oncogenomics 2019:465-475

Liquid Biopsy Testing for the Management of Patient with Non-Small Cell Lung Cancer Carrying a Rare Exon-20 EGFR Insertion.

Authors: Morabito, Alessandro, Manzo, Anna, Montanino, Agnese, Rachiglio, Anna Maria, Sforza, Vincenzo, Pasquale, Raffaella, Costanzo, Raffaele, Maiello, Monica R, Sandomenico, Claudia, Gallo, Marianna, Palumbo, Giuliano, Luca, Antonella De, La Rocca, Antonello, Martucci, Nicola, Cecio, Rossella De, Picone, Carmine, Lastoria, Secondo, Normanno, Nicola

Source: Oncologist; Jan2022, Vol. 27 Issue 1, p7-12, 6p, 1 Color Photograph, 1 Graph

Subject Terms: NUCLEIC acid analysis, LUNG cancer prevention, GENETIC mutation, SEQUENCE analysis, EPIDERMAL growth factor receptors, ERLOTINIB, METASTASIS, PROTEIN-tyrosine kinase inhibitors, BRAIN tumors, BONE tumors, POSITRON emission tomography, BODY fluid examination, EXTRACELLULAR space, GENE amplification, DISEASE management, DRUG resistance in cancer cells, DISEASE remission

multiple network-based bioinformatics pipeline for the study of molecular mechanisms in oncological diseases for personalized medicine.

Authors: Dotolo, Serena¹, Marabotti, Anna², Rachiglio, Anna Maria³, Abate, Riziero Esposito⁴, Benedetto, Marco⁵, Ciardiello, Fortunato⁶, Luca, Antonella De³, Normanno, Nicola³, Facchiano, Angelo⁷, Tagliaferri, Roberto¹, robtag@unisa.it

Source: Briefings in Bioinformatics; Nov2021, Vol. 22 Issue 6, p1-13, 13p

Dynamics of RAS/BRAF Mutations in cfDNA from Metastatic Colorectal Carcinoma Patients Treated with Polychemotherapy and Anti-EGFR Monoclonal Antibodies.

Authors: Rachiglio, Anna Maria¹ (AUTHOR) am.rachiglio@istitutotumori.na.it, Forgione, Laura¹ (AUTHOR) l.forgione@istitutotumori.na.it, Pasquale, Raffaella¹ (AUTHOR) r.pasquale@istitutotumori.na.it, Barone, Carlo Antonio² (AUTHOR) carloantonio.barone@policlinicogemelli.it, Maiello, Evaristo³ (AUTHOR) e.maiello@libero.it, Antonuzzo, Lorenzo⁴ (AUTHOR) lorenzo.antonuzzo@gmail.com, Cassata, Antonino⁵ (AUTHOR) a.cassata@istitutotumori.na.it, Tonini, Giuseppe⁶ (AUTHOR) g.tonini@unicampus.it, Bordonaro, Roberto⁷ (AUTHOR) oncoct@hotmail.com, Rosati, Gerardo⁸ (AUTHOR) oncogerry@yahoo.it, Zaniboni, Alberto⁹ (AUTHOR) alberto.zaniboni@poliambulanza.it, Lonardi, Sara¹⁰ (AUTHOR) sara.lonardi@iov.veneto.it, Ferrari, Daris¹¹ (AUTHOR) daris.ferrari@unimi.it, Frassineti, Giovanni Luca¹² (AUTHOR) luca.frassineti@irst.emr.it, Tamberi, Stefano¹³ (AUTHOR) stefano.tamberi@auslromagna.it, Pisconti, Salvatore¹⁴ (AUTHOR) salvatorepisconti@hotmail.it, Di Fabio, Francesca¹⁵ (AUTHOR) francesca.difabio@aosp.bo.it, Roma, Cristin¹ (AUTHOR) c.roma@istitutotumori.na.it, Orlandi, Armando² (AUTHOR) armando.orlandi@policlinicogemelli.it, Latiano, Tiziana³ (AUTHOR) t.latiano@operapadrepio.it

Source: Cancers. Feb2022, Vol. 14 Issue 4, p1052. 1p.

Subject Terms: *CANCER chemotherapy, *THERAPEUTIC use of monoclonal antibodies, *THERAPEUTIC use of antineoplastic agents, *GENETIC mutation, *COMBINATION drug therapy, *DNA, *EPIDERMAL growth factor receptors, *BLOOD plasma, *METASTASIS, *COLORECTAL cancer, *TREATMENT effectiveness, *EXTRACELLULAR space, *NUCLEIC acids, *BLOOD, *EVALUATION

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List of Contributors

Authors: Abdelhay, Eliana, Adiseshaiah, Pavan P., Aglietta, Massimo, Allègra, Maryline, Ascierto, Paolo A., Bastus, Nuria Coll, Basudan, Ahmed, Berghuis, A.M. Sofie, Biasco, Guido, Binato, Renata, Borah, Ankita, Brown, Janet E., Cappelletti, Vera, Chan, Sock Hoai, Chen, Alice P., Chen, Ru, Chénard-Poirier, Maxime, Chicchinelli, Nicoletta, Cives, Mauro, Conte, Pierfranco, Corrêa, Stephany, Costanzo, Raffaele, Coyne, Geraldine O’Sullivan, Cristofanilli, Massimo, Daidone, Maria Grazia, Dammacco, Franco, Daniele, Gennaro, De Nola, Rosalba, Dendooven, Amélie, Di Cosimo, Serena, Di Maio, Massimo, Dieci, Maria Vittoria, D’Ambrosio, Lorenzo, D’Oronzo, Stella, Fehm, Tanja, Fenizia, Francesca, Ferrari, Paola, Ghai, Vikas, Giuliano, Mario, Gopalan, Vinod, Grassi, Paolo, Grignani, Giovanni, Guarneri, Valentina, Gyanchandani, Rekha, Heeke, Simon, Hofman, Paul, Hofman, Véronique, Iannaccone, Alessia, Ilié, Marius, Islam, Farhadul, Iuliani, Michele, Kennedy, Richard, Kozlov, Serguei, Kumar, D. Sakthi, Lam, Alfred King-Yin, Lampignano, Rita, Lauriola, Mattia, Lee, Adrian V., Lee, Inyoul, Leone, Patrizia, Lovero, Domenica, Lu, Yong-Jie, Malapelle, Umberto, Manca, Paolo, Mannavola, Francesco, Manzo, Anna, McCabe, Nuala, Meierjohann, Svenja, Merlini, Alessandra, Michalarea, Vasiliki, Montanino, Agnese, Morabito, Alessandro, Nannini, Margherita, Nawroth, Roman, Neubauer, Hans, Ngeow, Joanne, Nicolini, Andrea, Normanno, Nicola, Palmirotta, Raffaele, Palumbo, Giuliano, Pan, Sheng, Panis, Carolina, Pantano, Francesco, Parkes, Eileen, Pasini, Luigi, Passarelli, Anna, Passiglia, Francesco, Pauwels, Patrick, Pellè, Eleonora, Peng, Hong, Perrone, Francesco, Phuong, Lisa, Piccirillo, Maria Carmela, Piekarz, Richard, Piiper, Albrecht, Pisapia, Pasquale, Priedigkeit, Nolan, Pucci, Michela, Quaresmini, Davide, Quek, Richard, Racanelli, Vito, Rachiglio, Anna Maria, Ratta, Raffaele, Ribelli, Giulia, Rolfo, Christian, Ryan, Joseph, Safa, Ahmad R., Salgado, Roberto, Sandomenico, Claudia, Sangiolo, Dario, Santini, Daniele, Schettini, Francesco, Schettino, Clorinda, Schilling, Bastian, Schoon, Jolanda J., Shimanovsky, Alexei, Silvestris, Erica, Silvestris, Franco, Simonetti, Sonia, Smyth, Elizabeth C., Somasundaram, Nagavalli, Søreide, Kjetil, Strosberg, Jonathan, Swierczewska, Magdalena, Takeshima, Hideyuki, Tonini, Giuseppe, Ushijima, Toshikazu, Vacca, Angelo, Vernaci, Grazia, Verzoni, Elena, Vietsch, Eveline E., Vincenzi, Bruno, Waidmann, Oliver, Wang, Kai, Wang, Xiaosheng, Wasser, Jeffery S., Wellstein, Anton, Wood, Steven L., Xu, Lei, Yamada, Harumi

Source: In Oncogenomics 2019:xv-xx

Letter to the Editor: Reply to Kobunai et al.

Authors: Carotenuto, Pietro, Roma, Cristin, Rachiglio, Anna Maria, Normanno, Nicola

Source: Pharmacogenomics. 12(3):309-310

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121256385.0x000001&indx=1&recIds=ETOCvdc_100121256385.0x000001

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