SARS‐CoV‐2 infections in patients enrolled on the Children's Oncology Group standard‐risk B‐cell acute lymphoblastic leukemia trial, AALL1731

Authors: Elgarten, Caitlin W., Kairalla, John A., Thompson, Joel C., Miller, Tamara P., Wang, Cindy, Conway, Susan, Loh, Mignon L., Raetz, Elizabeth A., Gupta, Sumit, Rau, Rachel E., Angiolillo, Anne, Rabin, Karen R., Alexander, Sarah

Source: EJHaem. 4(3):745-750

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192730212.0x000001&indx=1&recIds=ETOCvdc_100192730212.0x000001

Ethnic‐specific predictors of neurotoxicity among patients with pediatric acute lymphoblastic leukemia after high‐dose methotrexate

Authors: Harris, Rachel D., Bernhardt, Melanie Brooke, Zobeck, Mark C., Taylor, Olga A., Gramatges, Maria Monica, Schafer, Eric S., Lupo, Philip J., Rabin, Karen R., Scheurer, Michael E., Brown, Austin L.

Source: Cancer. 129(8):1287-1294

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181674868.0x000001&indx=1&recIds=ETOCvdc_100181674868.0x000001

Novel and replicated clinical and genetic risk factors for toxicity from high‐dose methotrexate in pediatric acute lymphoblastic leukemia

Authors: Zobeck, Mark, Bernhardt, M. Brooke, Kamdar, Kala Y., Rabin, Karen R., Lupo, Philip J., Scheurer, Michael E.

Source: Pharmacotherapy. 43(3):205-214

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177479014.0x000001&indx=1&recIds=ETOCvdc_100177479014.0x000001

Prognostic significance of ETP phenotype and minimal residual disease in T-ALL: a Children’s Oncology Group study

Authors: Wood, Brent L., Devidas, Meenakshi, Summers, Ryan J., Chen, Zhiguo, Asselin, Barbara, Rabin, Karen R., Zweidler-McKay, Patrick A., Winick, Naomi J., Borowitz, Michael J., Carroll, William L., Raetz, Elizabeth A., Loh, Mignon L., Hunger, Stephen P., Dunsmore, Kimberly P., Teachey, David T., Winter, Stuart S.

Source: In Blood 14 December 2023 142(24):2069-2078

Survival outcomes of children with relapsed or refractory myeloid leukemia associated with Down syndrome

Authors: Raghuram, Nikhil, Hasegawa, Daisuke, Nakashima, Kentaro, Rahman, Syaza, Antoniou, Evangelia, Skajaa, Torjus, Merli, Pietro, Verma, Anupam, Rabin, Karen R., Aftandilian, Catherine, Kotecha, Rishi S., Cheuk, Daniel, Jahnukainen, Kirsi, Kolenova, Alexandra, Balwierz, Walentyna, Norton, Alice, O’Brien, Maureen, Cellot, Sonia, Chopek, Ashley, Arad-Cohen, Nira, Goemans, Bianca, Rojas-Vasquez, Marta, Ariffin, Hany, Bartram, Jack, Kolb, E. Anders, Locatelli, Franco, Klusmann, Jan-Henning, Hasle, Henrik, McGuire, Bryan, Hasnain, Afia, Sung, Lillian, Hitzler, Johann

Source: In Blood Advances 14 November 2023 7(21):6532-6539

Genomic landscape of Down syndrome–associated acute lymphoblastic leukemia

Authors: Li, Zhenhua, Chang, Ti-Cheng, Junco, Jacob J., Devidas, Meenakshi, Li, Yizhen, Yang, Wenjian, Huang, Xin, Hedges, Dale J., Cheng, Zhongshan, Shago, Mary, Carroll, Andrew J., Heerema, Nyla A., Gastier-Foster, Julie, Wood, Brent L., Borowitz, Michael J., Sanclemente, Lauren, Raetz, Elizabeth A., Hunger, Stephen P., Feingold, Eleanor, Rosser, Tracie C., Sherman, Stephanie L., Loh, Mignon L., Mullighan, Charles G., Yu, Jiyang, Wu, Gang, Lupo, Philip J., Rabin, Karen R., Yang, Jun J.

Source: In Blood 13 July 2023 142(2):172-184

Central nervous system status is prognostic in T-cell acute lymphoblastic leukemia: a Children’s Oncology Group report

Authors: Gossai, Nathan P., Devidas, Meenakshi, Chen, Zhiguo, Wood, Brent L., Zweidler-McKay, Patrick A., Rabin, Karen R., Loh, Mignon L., Raetz, Elizabeth A., Winick, Naomi J., Burke, Michael J., Carroll, Andrew J., Esiashvili, Natia, Heerema, Nyla A., Carroll, William L., Hunger, Stephen P., Dunsmore, Kimberly P., Winter, Stuart S., Teachey, David T.

Source: In Blood 13 April 2023 141(15):1802-1811

Antileukemic properties of the kinase inhibitor OTSSP167 in T-cell acute lymphoblastic leukemia

Authors: Bridges, Cory Seth, Chen, Taylor J., Puppi, Monica, Rabin, Karen R., Lacorazza, H. Daniel

Source: In Blood Advances 14 February 2023 7(3):422-435

Racial and ethnic disparities in childhood and young adult acute lymphocytic leukaemia: secondary analyses of eight Children's Oncology Group cohort trials

Authors: Gupta, Sumit ^*, Dai, Yunfeng, Chen, Zhiguo, Winestone, Lena E, Teachey, David T, Bona, Kira, Aplenc, Richard, Rabin, Karen R, Zweidler-McKay, Patrick, Carroll, Andrew J, Heerema, Nyla A, Gastier-Foster, Julie, Borowitz, Michael J, Wood, Brent L, Maloney, Kelly W, Mattano, Leonard A, Jr, Larsen, Eric C, Angiolillo, Anne L, Burke, Michael J, Salzer, Wanda L, Winter, Stuart S, Brown, Patrick A, Guest, Erin M, Dunsmore, Kimberley P, Kairalla, John A, Winick, Naomi J, Carroll, William L, Raetz, Elizabeth A, Hunger, Stephen P, Loh, Mignon L, Devidas, Meenakshi

Source: In The Lancet Haematology February 2023 10(2):e129-e141

Rates of laboratory adverse events by course in paediatric leukaemia ascertained with automated electronic health record extraction: a retrospective cohort study from the Children's Oncology Group

Authors: Miller, Tamara P, Getz, Kelly D, Li, Yimei, Demissei, Biniyam G, Adamson, Peter C, Alonzo, Todd A, Burrows, Evanette, Cao, Lusha, Castellino, Sharon M, Daves, Marla H, Fisher, Brian T, Gerbing, Robert, Grundmeier, Robert W, Krause, Edward M, Lee, Judy, Lupo, Philip J, Rabin, Karen R, Ramos, Mark, Scheurer, Michael E, Wilkes, Jennifer J, Winestone, Lena E, Hawkins, Douglas S, Gramatges, M Monica, Aplenc, Richard

Source: Lancet.Haematology. 9(9):e678-e688

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CRLF2 overexpression results in reduced B-cell differentiation and upregulated E2F signaling in the Dp16 mouse model of Down syndrome

Authors: Junco, Jacob J., Zorman, Barry, Gant, Vincent U., Muñoz, Jaime, Lacorazza, H. Daniel, Sumazin, Pavel, Rabin, Karen R.

Source: Experimental hematology. 110:34-38

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179202534.0x000001&indx=1&recIds=ETOCvdc_100179202534.0x000001

Residence in a Latinx enclave and end-induction minimal residual disease positivity among children with acute lymphoblastic leukemia

Authors: Muñiz, Joshua P., Woodhouse, John P., Hughes, Amy E., Pruitt, Sandi L., Rabin, Karen R., Scheurer, Michael E., Lupo, Philip J., Schraw, Jeremy M.

Source: Pediatric hematology and oncology. 39(7):650-657

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165283628.0x000001&indx=1&recIds=ETOCvdc_100165283628.0x000001

An updated assessment of 43, 110 patients enrolled in the Childhood Cancer Research Network: A Children's Oncology Group report

Authors: Brown, Austin L., Sok, Pagna, Scheurer, Michael E., Rabin, Karen R., Marcotte, Erin L., Hawkins, Douglas S., Spector, Logan G., Lupo, Philip J.

Source: Cancer. 128(14):2760-2767

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153654659.0x000001&indx=1&recIds=ETOCvdc_100153654659.0x000001

Sex‐based disparities in outcome in pediatric acute lymphoblastic leukemia: a Children's Oncology Group report

Authors: Gupta, Sumit, Teachey, David T., Chen, Zhiguo, Rabin, Karen R., Dunsmore, Kimberly P., Larsen, Eric C., Maloney, Kelly W., Mattano, Leonard A., Winter, Stuart S., Carroll, Andrew J., Heerema, Nyla A., Borowitz, Michael J., Wood, Brent L., Carroll, William L., Raetz, Elizabeth A., Winick, Naomi J., Loh, Mignon L., Hunger, Stephen P., Devidas, Meenakshi

Source: Cancer. 128(9):1863-1870

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148376192.0x000001&indx=1&recIds=ETOCvdc_100148376192.0x000001

Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children.

Authors: Gupta, Sumit^1,2, Rau, Rachel E.^3,4, Kairalla, John A.⁵, Rabin, Karen R.⁶, Wang, Cindy⁵, Angiolillo, Anne L.⁷, Alexander, Sarah^1,2, Carroll, Andrew J.⁸, Conway, Susan⁵, Gore, Lia⁹, Kirsch, Ilan¹⁰, Kubaney, Holly R.¹¹, Li, Amanda M.¹², McNeer, Jennifer L.¹³, Militano, Olga¹⁴, Miller, Tamara P.¹⁵, Moyer, Yvonne¹⁶, O'Brien, Maureen M.⁹, Okada, Maki¹⁷, Reshmi, Shalini C.¹⁸

Source: New England Journal of Medicine; 2/27/2025, Vol. 392 Issue 9, p875-891, 17p

Delayed excretion of high‐dose methotrexate in pediatric acute leukemia correlates with laxative and constipation management.

Authors: Belsky, Jennifer A., Chavana, Ashley, Banerjee, Ankona, Zobeck, Mark, Schafer, Eric S., Rabin, Karen R., Gramatges, Monica, Sim, Alex, Leisinger, Audrey, Reddy, Trisha, Parod, Megan J., Lupo, Philip, Scheurer, Michael, Brown, Austin L., Bernhardt, M. Brooke

Source: Pediatric Blood & Cancer; Jan2025, Vol. 72 Issue 1, p1-7, 7p

Co-targeting of the thymic stromal lymphopoietin receptor to decrease immunotherapeutic resistance in CRLF2-rearranged Ph-like and Down syndrome acute lymphoblastic leukemia

Authors: Balestra, Tommaso, Niswander, Lisa M, Bagashev, Asen, Loftus, Joseph P, Ross, Savannah L, Chen, Robert K, McClellan, Samantha M, Junco, Jacob J, Bárcenas López, Diego A, Rabin, Karen R., Fry, Terry J, Tasian, Sarah K

Source: Leukemia; March 2025, Vol. 39 Issue: 3 p555-567, 13p

Molecular basis of ETV6-mediated predisposition to childhood acute lymphoblastic leukemia

Authors: Nishii, Rina ^*, Baskin-Doerfler, Rebekah ^*, Yang, Wentao, Oak, Ninad, Zhao, Xujie, Yang, Wenjian, Hoshitsuki, Keito, Bloom, Mackenzie, Verbist, Katherine, Burns, Melissa, Li, Zhenhua, Lin, Ting-Nien, Qian, Maoxiang, Moriyama, Takaya, Gastier-Foster, Julie M., Rabin, Karen R., Raetz, Elizabeth, Mullighan, Charles, Pui, Ching-Hon, Yeoh, Allen Eng-Juh, Zhang, Jinghui, Metzger, Monika L., Klco, Jeffery M., Hunger, Stephen P., Newman, Scott, Wu, Gang, Loh, Mignon L., Nichols, Kim E. ^*, Yang, Jun J. ^*

Source: In Blood 21 January 2021 137(3):364-373

An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance

Authors: Junco, Jacob J., Chen, Taylor, Rashid, Raushan, Terrell, Maci, Gant, Vincent U., Miller, Matthew, Rau, Rachel, Lacorazza, H. Daniel, Rabin, Karen R.

Source: Leukemia. 35(6):1777-1781

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100192938676.0x000001&indx=1&recIds=ETOCvdc_100192938676.0x000001

Automated Electronic Health Record Data Extraction and Curation Using ExtractEHR.

Authors: Miller, Tamara P., Getz, Kelly D., Krause, Edward, Jo, Yun Gun, Charapala, Sandhya, Gramatages, M. Monica, Rabin, Karen, Scheurer, Michael E., Wilkes, Jennifer J., Fisher, Brian T., Aplenc, Richard

Source: JCO Clinical Cancer Informatics; 11/25/2024, Vol. 8, p1-8, 8p

Subject Terms: CHILDREN'S hospitals, ELECTRONIC health records, PEDIATRIC oncology, RESEARCH questions, CHILDHOOD cancer