Potential application and prospects of ROS-sensitive biomaterials in cancer therapy: a immune microenvironment triggered nanomaterial

Authors: Weiming Huang, Pengju Zhang, Eryong Zhao, Jian Xiong, Shaokun Wang, Zi Lv

Source: Discover Oncology, Vol 16, Iss 1, Pp 1-18 (2025)

Subject Terms: ROS-responsive material, ROS-responsive nanomaterial, Smart nanoparticles, Stimuli-sensitive nanoparticles, Targeted drug delivery, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2730-6011

Access URL: https://doaj.org/article/91e0cc4183694151b4e26cc64f271f06

Injectable hydrogels with ROS-triggered drug release enable the co-delivery of antibacterial agent and anti-inflammatory nanoparticle for periodontitis treatment

Authors: Yujing Zhu, Ziliang Xiu, Xiaoxi Jiang, Huifang Zhang, Xiaofeng Li, Yunru Feng, Bojiang Li, Rui Cai, Chunhui Li, Gang Tao

Source: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-31 (2025)

Subject Terms: Periodontitis, ROS-responsive hydrogels, Drug delivery, Antibacterial, Anti-inflammation, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/e90ec3be522841249a7481c517a826c8

A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression

Authors: Qiuyang Wang, Kai Feng, Guangsheng Wan, Wei Liao, Jing Jin, Peng Wang, Xiaolian Sun, Weijun Wang, Qing Jiang

Source: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-21 (2025)

Subject Terms: Osteoarthritis, Metalloproteinase-13 siRNA nanocarrier, ROS-responsive Hydrogel, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/b863f9ab20b34712a28ef60fc9cdcbef

A reactive oxygen species-responsive hydrogel loaded with Apelin-13 promotes the repair of spinal cord injury by regulating macrophage M1/M2 polarization and neuroinflammation

Authors: Zhiyue Li, Qun Zhao, Jiahui Zhou, Yuyan Li, Yifan Zheng, Linxi Chen

Source: Journal of Nanobiotechnology, Vol 23, Iss 1, Pp 1-18 (2025)

Subject Terms: Spinal cord injury (SCI), Apelin-13, ROS-responsive hydrogel, Macrophage M1/M2 polarization, Immune microenvironment, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/76f0fac96f9c487f8321f226967c8b30

Bacteria-activated macrophage membrane coated ROS-responsive nanoparticle for targeted delivery of antibiotics to infected wounds

Authors: Ying Luo, Xiaoli Jia, Xiaozhuo Wu, Ling Diao, Yawei Zhao, Xing Liu, Yi Peng, Wen Zhong, Malcolm Xing, Guozhong Lyu

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)

Subject Terms: Bacteria-activation, Macrophage membrane, ROS-responsive nanoparticle, Targeted delivery, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/d02fd7f35dd041dfafec86835d616947

A shielded cascade of targeted nanocarriers spanning multiple microenvironmental barriers for inflammatory disease therapy

Authors: Fengyi Liu, Xu Wang, Mingxing Ren, Ping He, Yuzhou Li, Jing Cui, Sheng Yang

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)

Subject Terms: Microenvironmental barriers, Reactive oxygen species (ROS)-responsive, Macrophage, PAMAM dendrimer, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/fe077d937e17433995497f0120cd2c5a

Spatiotemporal-controllable ROS-responsive camptothecin nano-bomb for chemo/photo/immunotherapy in triple-negative breast cancer

Authors: Wenjie Xu, Zhaokui Zeng, Yucheng Tang, Jingjing Tian, Xinyan Hao, Pengcheng Sun, Yanjin Peng, Tian Tian, Daxiong Xiang, Rongrong Wang, Chuanpin Chen, Junyong Wu

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-23 (2024)

Subject Terms: Spatiotemporal-controllable, Self-assembly, ROS-responsive prodrug, Combination therapy, ICD, Anti-metastasis, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/de00503d81f743a7b6b3ab0c613b65df

Recent advances in reactive oxygen species (ROS)-responsive drug delivery systems for photodynamic therapy of cancer

Authors: Danrong Hu, Yicong Li, Ran Li, Meng Wang, Kai Zhou, Chengqi He, Quan Wei, Zhiyong Qian

Source: Acta Pharmaceutica Sinica B, Vol 14, Iss 12, Pp 5106-5131 (2024)

Subject Terms: Photodynamic therapy, ROS-responsive, Drug delivery systems, Cancer therapy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383524004167; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/fe2410dd580649df916f2d73b0d0f8f6

Polydopamine(PDA)-coated diselenide-bridged mesoporous silica-based nanoplatform for neuroprotection by reducing oxidative stress and targeting neuroinflammation in intracerebral hemorrhage

Authors: Fangfang Zhou, Yongju He, Meiru Zhang, Xiyu Gong, Xiaoxuan Liu, Ranran Tu, Binbin Yang

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)

Subject Terms: Intracerebral hemorrhage, Polydopamine-coated diselenide bridged mesoporous silica nanoparticle, ROS-responsive, Microglia polarization, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/97642409644c4cc2bf170bfb0f53d9ef

Ischemic Area‐Targeting and Self‐Monitoring Nanoprobes Ameliorate Myocardial Ischemia/Reperfusion Injury by Scavenging ROS and Counteracting Cardiac Inflammation

Authors: Xiaobin Ma, Zhijin Fan, Jingyan Peng, Liming Nie

Source: Advanced Science, Vol 12, Iss 11, Pp n/a-n/a (2025)

Subject Terms: inflammation, myocardial ischemia/reperfusion injury, photoacoustic imaging, reactive oxygen species, ROS‐responsive nanoprobes, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/9d8b14e0153a468d8c0cac48c315a938

Traditional Chinese Medicine Borneol‐Based Polymeric Micelles Intracerebral Drug Delivery System for Precisely Pathogenesis‐Adaptive Treatment of Ischemic Stroke

Authors: Yanan Wang, Xutao Ma, Xinyuan Wang, Liru Liu, Xue Zhang, Qiuyue Wang, Yingfei Zhu, Huanhua Xu, Liangmin Yu, Zhiyu He

Source: Advanced Science, Vol 12, Iss 9, Pp n/a-n/a (2025)

Subject Terms: BAPTA‐AM, blood‐brain barrier, borneol, ischemic stroke, ROS‐responsive, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/eb92bc376b49461ebd23b89e17bb8601

Hepatoma-Targeting and ROS-Responsive Polymeric Micelle-Based Chemotherapy Combined with Photodynamic Therapy for Hepatoma Treatment

Authors: Xu X, Lu W, Zhang H, Wang X, Huang C, Huang Q, Xu W

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 9613-9635 (2024)

Subject Terms: ros-responsive polymeric micelles, photodynamic therapy, hepatoma-targeting, celastrol, combination anti-hepatoma therapy, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/hepatoma-targeting-and-ros-responsive-polymeric-micelle-based-chemothe-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/89c43b0d68eb4b1ebeb2f16bca9aad0d

ROS-responsive nanoparticle delivery of ferroptosis inhibitor prodrug to facilitate mesenchymal stem cell-mediated spinal cord injury repair

Authors: Renshuai Hua, Chenxi Zhao, Zhengyu Xu, Derong Liu, Wenyuan Shen, Wenlu Yuan, Yan Li, Jun Ma, Zhishuo Wang, Shiqing Feng

Source: Bioactive Materials, Vol 38, Iss , Pp 438-454 (2024)

Subject Terms: Spinal cord injury, Huc-MSCs, ROS-Responsive nanoparticles, Ferroptosis inhibitor, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24001816; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/67c368aa2fd143fbb3e1f4f5e8336880

ROS-Responsive Nanoprobes for Bimodal Imaging-Guided Cancer Targeted Combinatorial Therapy

Authors: Jiang F, Liu S, Wang L, Chen H, Huang Y, Cao Y, Wang X, Lin M, Zhang J

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 8071-8090 (2024)

Subject Terms: targeted drug delivery, photodynamic therapy, ros-responsive chemotherapy, bimodal imaging, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/ros-responsive-nanoprobes-for-bimodal-imaging-guided-cancer-targeted-c-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/40f70fe8dc374848aa841ad46c9d74bc

ROS-responsive hydrogel for bone regeneration: Controlled dimethyl fumarate release to reduce inflammation and enhance osteogenesis

Authors: Huang, Qiuxia ^{a, b}, Qu, Yang ^{a, b}, Tang, Mengchen ^{a, b}, Lan, Kaiwen ^{a, b}, Zhang, Yilin ^{a, b}, Chen, Sishi ^{a, b}, Li, Weichang ^{a, b, ⁎}, Gu, Lisha ^{a, b, ⁎}

Source: In Acta Biomaterialia 15 March 2025 195:183-200

Bidirectional amplification of oxidative stress through the mitochondria-targeted Co-Delivery of nanogolds and chlorin e6 Using ROS-responsive organosilica nanocarriers

Authors: Yu, Dongsheng ^{a, b}, Yuan, Jianming ^b, Ou, Chiyi ^b, Chen, Qinghua ^b, Li, Haowen ^b, Hao, Chenhui ^b, Zheng, Jiaojiao ^b, Liu, Shuang ^b, Li, Mingqiang ^{a, ⁎}, Cheng, Du ^{b, ⁎}

Source: In Acta Biomaterialia 15 March 2025 195:309-320

ROS-responsive core–shell microgels for phase-specific treatment of myocardial infarction via programmed drug delivery

Authors: Song, Liang ^a, Zheng, Weiwei ^{a, c}, Wang, Shuqin ^a, Zhai, Zihe ^a, Li, Shifen ^a, Ding, Jie ^a, Shen, Liyin ^a, Zhang, Jinyue ^a, Zhu, Yang ^{a, d, ⁎}, Gao, Changyou ^{a, b, c, d, ⁎}

Source: In Chemical Engineering Journal 1 March 2025 507

Self-assembled ROS -responsive podollyllotoxin twin drug nanoparticles for enhanced anticancer therapy

Authors: Chen, Lei ^{a, 1}, Liu, Jiabao ^{a, 1}, Gui, Chunxiang ^a, mei, Ke ^b, Dai, Xiaoshuang ^b, Song, Yang ^a, Jiang, Daobing ^a, Deng, Lian ^b, Liu, Junda ^a, Qiu, Neng ^{a, ⁎}

Source: In Journal of Drug Delivery Science and Technology March 2025 105

An oxidation-reduction-triggered thiamine disulfide-based prodrug of 10-hydroxycamptothecin for selective tumor cell locking and therapeutic delivery

Authors: Yang, Chunyan ^a, Yu, Peiyun ^a, Chen, Jinxia ^a, Lu, Runxin ^b, Hai, Li ^a, Yang, Zhongzhen ^{c, ⁎⁎}, Guo, Li ^{a, ⁎⁎⁎}, Wu, Yong ^{a, ⁎}

Source: In European Journal of Medicinal Chemistry 15 February 2025 284

ROS sensitive adaptive injectable hydrogels Based on GAPBA nanofibers and PVA/EGCG for accelerating diabetic wound healing through regulating the inflammation microenvironment

Authors: Wu, Caixia ^{a, 1}, Ning, Xiaoqun ^{b, 1}, Zhang, Ruoqi ^{c, 1}, Liu, Qunfeng ^d, Zhou, Xiaoyan ^{e, ⁎}, Guo, Huilong ^{a, ⁎}

Source: In European Polymer Journal 14 February 2025 225