Evaluation of Rho kinase inhibitor effects on neuroprotection and neuroinflammation in an ex-vivo retinal explant model

Authors: Élodie Reboussin, Paul Bastelica, Ilyes Benmessabih, Arnaud Cordovilla, Cécile Delarasse, Annabelle Réaux-Le Goazigo, Françoise Brignole-Baudouin, Céline Olmière, Christophe Baudouin, Juliette Buffault, Stéphane Mélik Parsadaniantz

Source: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-21 (2024)

Subject Terms: Glaucoma, Rho kinase inhibitor, Neuroprotection, Immunomodulation, RNAseq analysis, Retinal explant, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/78539926c1e24f9ea37b32a906073d74

Investigating mechanical and inflammatory pathological mechanisms in osteoarthritis using MSC-derived osteocyte-like cells in 3D

Authors: Sophie J. Gilbert, Ryan Jones, Ben J. Egan, Cleo Selina Bonnet, Sam L. Evans, Deborah J. Mason

Source: Frontiers in Endocrinology, Vol 15 (2024)

Subject Terms: osteocyte, mechanical load, osteoarthritis, inflammation, 3D model, RNAseq analysis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1359052/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/60634a5c91fd4126a4250923903c1936

Spotlight on Secondary Metabolites Produced by an Early-Flowering Apulian Artichoke Ecotype Sanitized from Virus Infection by Meristem-Tip-Culture and Thermotherapy

Authors: Roberta Spanò, Patrizia Gena, Vito Linsalata, Valeria Sini, Isabella D’Antuono, Angela Cardinali, Pietro Cotugno, Giuseppe Calamita, Tiziana Mascia

Source: Antioxidants, Vol 13, Iss 7, p 852 (2024)

Subject Terms: artichoke, antioxidant and antimicrobial effects, anti-inflammatory effects, polyphenol extracts, supercritical fluid extraction, RNAseq analysis, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/13/7/852; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/5b830c90572e4e0599c200f2fe67b2eb

Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire

Authors: Eliza M. Gordon-Lipkin, Payal Banerjee, Jose Luis Marin Franco, Tatiana Tarasenko, Shannon Kruk, Elizabeth Thompson, Derek E. Gildea, Suiyuan Zhang, Tyra G. Wolfsberg, NISC Comparative Sequencing Program, Willy A. Flegel, Peter J. McGuire

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: B cells, mitochondria, viral infection, VirScan, RNAseq analysis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1142634/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f3844f77f56c403f931ed7b8f9d60ad3

Immune cell proportions correlate with clinicogenomic features and ex vivo drug responses in acute myeloid leukemia

Authors: Kyle A. Romine, Daniel Bottomly, William Yashar, Nicola Long, Matthew Viehdorfer, Shannon K. McWeeney, Jeffrey W. Tyner

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: AML – acute myeloid leukemia, immune therapeutics, checkpoint inhibition therapy, RNAseq analysis, functional genomic data, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1192829/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/9251dcb7a94c4cb194fdc06f503f7fdd

Methods for assessment of the tumour microenvironment and immune interactions in non-small cell lung cancer. A narrative review

Authors: Kanishka Rangamuwa, Christian Aloe, Michael Christie, Marie-Liesse Asselin-Labat, Daniel Batey, Lou Irving, Thomas John, Steven Bozinovski, Tracy L. Leong, Daniel Steinfort

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: cytometry, immunohistochemistry, RNAseq analysis, non-smal cell lung cancer, tumour microenvironment, immune interaction, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1129195/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/33adfc9b0eb947d78306dcd6190ad48a

Expanding the molecular spectrum of tenosynovial giant cell tumors

Authors: Thibault Gauduchon, Helene Vanacker, Daniel Pissaloux, Philippe Cassier, Armelle Dufresne, Marie Karanian, Alexandra Meurgey, Amine Bouhamama, François Gouin, Isabelle Ray-Coquard, Jean-Yves Blay, Franck Tirode, Mehdi Brahmi

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: tenosynovial giant cell tumor (TGCT), CSF1, CSF1 fusion transcript, RNAseq analysis, expression profile, gene fusions, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.1012527/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/207e1292ce8e4d09892f6ace094f5615

A Novel Combined Use of Dupilumab for Treatment of Aggressive Refractory Pemphigus Vulgaris Complicated With Pulmonary Tuberculosis: A Case Report and the RNA-seq Analysis

Authors: Siji Chen, Shaowei Zhan, Chunting Hua, Yi Tang, Hao Cheng

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: pemphigus vulgaris (PV), dupilumab, autoimmune disease, RNAseq analysis, biologic agents (biologies), case report, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.825796/full; https://doaj.org/toc/1664-3224

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CD33 Delineates Two Functionally Distinct NK Cell Populations Divergent in Cytokine Production and Antibody-Mediated Cellular Cytotoxicity

Authors: Maryam Hejazi, Congcong Zhang, Sabrina B. Bennstein, Vera Balz, Sarah B. Reusing, Melissa Quadflieg, Keven Hoerster, Stefan Heinrichs, Helmut Hanenberg, Sebastian Oberbeck, Marcus Nitsche, Sophie Cramer, Rita Pfeifer, Pranav Oberoi, Heiko Rühl, Johannes Oldenburg, Peter Brossart, Peter A. Horn, Florian Babor, Winfried S. Wels, Johannes C. Fischer, Nina Möker, Markus Uhrberg

Source: Frontiers in Immunology, Vol 12 (2022)

Subject Terms: NK cell, CD33-CAR, cytokine production and cytotoxicity, RNAseq analysis, NK cell expansion, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.798087/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4c25f962481b401c9f9ed4e85508f881

Transcriptional Changes in Regulatory T Cells From Patients With Autoimmune Polyendocrine Syndrome Type 1 Suggest Functional Impairment of Lipid Metabolism and Gut Homing

Authors: Amund Holte Berger, Eirik Bratland, Thea Sjøgren, Marte Heimli, Torgeir Tyssedal, Øyvind Bruserud, Stefan Johansson, Eystein Sverre Husebye, Bergithe Eikeland Oftedal, Anette Susanne Bøe Wolff

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: APS-1, autoimmune polyendocrine syndrome type 1, Tregs (regulatory T cells), RNAseq analysis, transcriptomics, flow cytometry, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.722860/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/984a8e46e7e948e780715b699fafface

The Acute Host-Response of Turkeys Colonized With Campylobacter coli

Authors: Matthew J. Sylte, Sathesh K. Sivasankaran, Julian Trachsel, Yuko Sato, Zuowei Wu, Timothy A. Johnson, Lawrance C. Chandra, Qijing Zhang, Torey Looft

Source: Frontiers in Veterinary Science, Vol 8 (2021)

Subject Terms: Meleagris gallopavo (Turkey), Campylobacter coli, cecal tonsil, RNAseq analysis, acute phase protein, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fvets.2021.613203/full; https://doaj.org/toc/2297-1769

Access URL: https://doaj.org/article/4e469b4b5371495e8ae46b585e6483c4

Desmoglein-4 Deficiency Exacerbates Psoriasiform Dermatitis in Rats While Psoriasis Patients Displayed a Decreased Gene Expression of DSG4

Authors: Tamara Moreno-Sosa, María Belén Sánchez, Elisa Olivia Pietrobon, Juan Manuel Fernandez-Muñoz, Felipe Carlos Martín Zoppino, Flavia Judith Neira, María José Germanó, Diego Esteban Cargnelutti, Alicia Carolina Innocenti, Graciela Alma Jahn, Susana Ruth Valdez, Juan Pablo Mackern-Oberti

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: psoriasis, desmoglein, T cell, inflammation, RNAseq analysis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.625617/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/beccd8492c584cacb074a7f090f68155

Olanzapine- induced metabolic syndrome pathogenesis: Hypothalamic 'leptin resistance' or 'pomc resistance'?

Authors: F. Veneziani, M. Zezza, A. Marakhovskaia, J.M. Beaulieu

Source: European Psychiatry, Vol 64, Pp S149-S150 (2021)

Subject Terms: Translational medicine, Metabolic syndrome, Hypothalamic RNAseq analysis, Psychopharmacology, Psychiatry, RC435-571

File Description: electronic resource

Relation: https://www.cambridge.org/core/product/identifier/S0924933821004089/type/journal_article; https://doaj.org/toc/0924-9338; https://doaj.org/toc/1778-3585

Access URL: https://doaj.org/article/46fa997f789f452283a3cd5d9152e4f6

Elevated Temperatures Impose Transcriptional Constraints and Elicit Intraspecific Differences Between Coffee Genotypes

Authors: Raphael Ricon de Oliveira, Thales Henrique Cherubino Ribeiro, Carlos Henrique Cardon, Lauren Fedenia, Vinicius Andrade Maia, Barbara Castanheira Ferrara Barbosa, Cecílio Frois Caldeira, Patricia E. Klein, Antonio Chalfun-Junior

Source: Frontiers in Plant Science, Vol 11 (2020)

Subject Terms: coffee breeding, global warming, energetic homeostasis, intraspecific variation, RNAseq analysis, sugar metabolism, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fpls.2020.01113/full; https://doaj.org/toc/1664-462X

Access URL: https://doaj.org/article/ab6fd09e3df7452680e54ea560d6c020

Hemophilia A Inhibitor Subjects Show Unique PBMC Gene Expression Profiles That Include Up-Regulated Innate Immune Modulators

Authors: Ahmad Faisal Karim, Anthony R. Soltis, Gauthaman Sukumar, Christoph Königs, Nadia P. Ewing, Clifton L. Dalgard, Matthew D. Wilkerson, Kathleen P. Pratt

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: hemophilia A, RNAseq analysis, innate and adaptive immune response, factor VIII (FVIII), PBMC (peripheral blood mononuclear cells), Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01219/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/82e845a0c3b84010b757baaccfdac88b

Exploring the RNA Gap for Improving Diagnostic Yield in Primary Immunodeficiencies

Authors: Jed J. Lye, Anthony Williams, Diana Baralle

Source: Frontiers in Genetics, Vol 10 (2019)

Subject Terms: primary immunodeficiency disorders, clinical diagnostics, RNASeq, RNA, RNAseq analysis, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2019.01204/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/085a2e7e20d944c5997f50030f7e736f

Comprehensive Assessment of BARD1 Messenger Ribonucleic Acid Splicing With Implications for Variant Classification

Authors: Logan C. Walker, Vanessa Lilian Lattimore, Anders Kvist, Petra Kleiblova, Petra Zemankova, Lucy de Jong, George A. R. Wiggins, Christopher Hakkaart, Simone L. Cree, Raquel Behar, Claude Houdayer, kConFab Investigators, Michael T. Parsons, Martin A. Kennedy, Amanda B. Spurdle, Miguel de la Hoya

Source: Frontiers in Genetics, Vol 10 (2019)

Subject Terms: breast cancer, mRNA splicing, nanopore sequencing, RNAseq analysis, variant classification, ACMG, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2019.01139/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/aef730ca4a5841118efe4b737619769d

The Functional and Molecular Effects of Doxycycline Treatment on Borrelia burgdorferi Phenotype

Authors: John R. Caskey, Nicole R. Hasenkampf, Dale S. Martin, Vladimir N. Chouljenko, Ramesh Subramanian, Mercedes A. Cheslock, Monica E. Embers

Source: Frontiers in Microbiology, Vol 10 (2019)

Subject Terms: Lyme disease, antibiotic, Borrelia (Borreliella) burgdorferi, RNASeq analysis, mice, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2019.00690/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/d6d45ad73c014f25a010cab3a25acdf5

Function of L-Pipecolic Acid as Compatible Solute in Corynebacterium glutamicum as Basis for Its Production Under Hyperosmolar Conditions

Authors: Fernando Pérez-García, Luciana F. Brito, Volker F. Wendisch

Source: Frontiers in Microbiology, Vol 10 (2019)

Subject Terms: pipecolic acid, osmo regulation, compatible solute, proline, Corynebacterium glutamicum, RNAseq analysis, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2019.00340/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/6da1a0ce92ae4658a272cb8317d49ed0

Studies Into β-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway

Authors: Jules Petit, Erin C. Bailey, Robert T. Wheeler, Carlos A. F. de Oliveira, Maria Forlenza, Geert F. Wiegertjes

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: β-glucan, primary macrophage, transcriptome analysis, RNAseq analysis, CTLD, C-type lectin-like domain, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00280/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/afc53596e87f44299fe8c5af5044cb01