RAC1 promotes the occurrence and development of tongue squamous cell carcinoma by regulating RAC1/PAK1/LIMK1 signaling pathway

Authors: Zongxuan He, Kai Song, Hongyu Han, Lin Wang, Zhenggang Chen, Wei Shang

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-10 (2025)

Subject Terms: RAC1, Tongue squamous cell carcinoma, Prognosis, Metastasis, EMT, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/dc59a949fe66437fa933237caa1cb0b7

Inhibition of RAC1 activator DOCK2 ameliorates cholestatic liver injury via regulating macrophage polarisation and hepatic stellate cell activation

Authors: Jianli Qiu, Yitong Qu, Yinli Li, Cancan Li, Junling Wang, Lu Meng, Xiaojin Jing, Jiangping Fu, Yan Xu, Yuna Chai

Source: Biology Direct, Vol 20, Iss 1, Pp 1-16 (2025)

Subject Terms: DOCK2, RAC1, Cholestasis, Liver fibrosis, Hepatic stellate cell, Macrophage polarisation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6150

Access URL: https://doaj.org/article/01c2ae99d7f64abc9993226eaf9fe520

Identification of core biomarkers for tuberculosis progression through bioinformatics analysis and in vitro research

Authors: Zhanpeng Chen, Qiong Wang, Quan Ma, Jinyun Chen, Xingxing Kong, Yuqin Zeng, Lanlan Liu, Shuihua Lu, Xiaomin Wang

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

Subject Terms: Mtb, TB, ELAVL1, RAC1, MRPL33, RBX1, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/649eb0a2024b4ab1873350e1fd6506ee

The mevalonate pathway contributes to breast primary tumorigenesis and lung metastasis

Authors: Javier Conde, Isabel Fernández‐Pisonero, L. Francisco Lorenzo‐Martín, Rocío García‐Gómez, Berta Casar, Piero Crespo, Xosé R. Bustelo

Source: Molecular Oncology, Vol 19, Iss 1, Pp 56-80 (2025)

Subject Terms: cholesterol, guanosine nucleotide exchange factors, oncogenic signaling, RAC1, RHO GTPases, sterol regulatory element‐binding protein, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/2c7e929d5aea4d67b1d799eeae224d67

Rac1 inhibition regenerates wounds in mouse fetuses via altered actin dynamics

Authors: Kento Takaya, Yuka Imbe, Qi Wang, Keisuke Okabe, Shigeki Sakai, Noriko Aramaki-Hattori, Kazuo Kishi

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Subject Terms: Rac1, Skin regeneration, Scar, Epidermis, Actin cable, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/7896e95462ec409097a1669d33599b30

Disulfidptosis: a novel cell death modality induced by actin cytoskeleton collapse and a promising target for cancer therapeutics

Authors: Tianyi Li, Ying Song, Lijuan Wei, Xiangyi Song, Ruifeng Duan

Source: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)

Subject Terms: Programmed cell death, Disulfidptosis, Disulfide stress, SLC7A11, Rac1, WAVE regulatory complex, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/f85bff2e034249bd8d12dc94bf30302f

Baxdrostat and finerenone: new aldosterone synthase-aldosterone-mineralocorticoid receptor hormonal system inhibitors for the drug treatment of resistant arterial hypertension

Authors: O. B. Kuzmin, N. V. Buchneva, V. V. Belyanin, V. V. Zhezha, M. V. Stolbova

Source: Рациональная фармакотерапия в кардиологии, Vol 20, Iss 4, Pp 451-459 (2024)

Subject Terms: resistant arterial hypertension, kidney, epithelial sodium channels, rho gtp-ase rac1, aldosterone synthase inhibitors, mineralcorticoid receptor antagonists, baxdrostat, finerenone, Therapeutics. Pharmacology, RM1-950, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.rpcardio.online/jour/article/view/3064; https://doaj.org/toc/1819-6446; https://doaj.org/toc/2225-3653

Access URL: https://doaj.org/article/be496d7d8bf642838f6ed14e7feca20d

Novel inhibitor against Rac1 for therapeutic approach in prevention of breast cancer progression

Authors: Abhinay Kunar Singh, Tirthankar Koley, Deepak Vats, Archana Singh, Ethayathulla Abdul Samath, Atul Batra, Sharmistha Dey

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: Breast cancer, Inhibitor, apoptosis, Rac1, Metastasis, Tumor, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/d3e6ac62ebf24a11a5f88e5f6d414e51

Mechanotransduction and inflammation: An updated comprehensive representation

Authors: Vennila Suriyagandhi, Ying Ma, Veronica Paparozzi, Tiziana Guarnieri, Biagio Di Pietro, Giovanna Maria Dimitri, Paolo Tieri, Claudia Sala, Darong Lai, Christine Nardini

Source: Mechanobiology in Medicine, Vol 3, Iss 1, Pp 100112- (2025)

Subject Terms: Mechanotransduction, RAC1, Systems biology markup language (SBML), Inflammation, Network analysis, Enrichment, Medical technology, R855-855.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2949907024000755; https://doaj.org/toc/2949-9070

Access URL: https://doaj.org/article/304b828026834d178bd58f06d442bdc0

Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration

Authors: Juanjuan Li, Yuling Ren, Hua Li, Zhikun Zheng

Source: Brazilian Journal of Medical and Biological Research, Vol 58 (2025)

Subject Terms: Age-related macular degeneration (AMD), Regulatory T cells (Tregs), Choroidal neovascularization, Angiogenesis, Rac1, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2025000100621&lng=en&tlng=en; http://www.scielo.br/pdf/bjmbr/v58/1414-431X-bjmbr-58-e14187.pdf; https://doaj.org/toc/1414-431X

Access URL: https://doaj.org/article/a6f32b648c0c472dbb866e3e6fecad9a

Single‐Cell Analysis of Endothelial Cell Injury in IgA Nephropathy

Authors: Yong‐Chang Yang, Lin Zhu, Jing‐Ying Zhao, Bo Zhang, Xiao‐Meng Wang, Wai W. Cheung, Cheng‐Guang Zhao, Ping Zhou

Source: Immunity, Inflammation and Disease, Vol 13, Iss 2, Pp n/a-n/a (2025)

Subject Terms: endothelial cell, IgA nephropathy, IL‐6, Rac1, scRNA‐seq, VE‐cadherin, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-4527

Access URL: https://doaj.org/article/c0e55ea549a4486ab1eddc6fb2e14814

A model for predicting bacteremia species based on host immune response

Authors: Peter Simons, Virginie Bondu, Laura Shevy, Stephen Young, Angela Wandinger-Ness, Cristian G. Bologa, Tione Buranda

Source: Frontiers in Cellular and Infection Microbiology, Vol 15 (2025)

Subject Terms: GTPases, Rac1 activation, bacteremia diagnosis, PLS-DA algorithm, G-Trap assay, flow cytometry, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2025.1451293/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/372f97fa2a674f7780adbdd2743ce2cf

Sodium arsenite induces islets β-cells apoptosis and dysfunction via SET-Rac1-mediated cytoskeleton disturbance

Authors: Tianming Qiu, Yu Zhi, Jingyuan Zhang, Ningning Wang, Xiaofeng Yao, Guang Yang, Liping Jiang, Li Lv, Xiance Sun

Source: Ecotoxicology and Environmental Safety, Vol 289, Iss , Pp 117641- (2025)

Subject Terms: Sodium arsenite, Islet β-cells, SET, Rac1, Cytoskeleton rearrangement, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0147651324017172; https://doaj.org/toc/0147-6513

Access URL: https://doaj.org/article/33250eda6e7a46cfbb1492169d985c27

Correlation analysis of serum Rac1 level with asthma control, airway inflammatory response and lung function in asthmatic children

Authors: Hui Fu, Yun Gao

Source: BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-9 (2024)

Subject Terms: Asthma, Rac1, Airway inflammatory response, Lung function, Disease control, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2466

Access URL: https://doaj.org/article/eb11f3b2d0074c15a946359903f227c3

Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in colorectal cancer

Authors: Aurora Cordaro, Maria Magdalena Barreca, Chiara Zichittella, Marco Loria, Denise Anello, Goffredo Arena, Nicolina Sciaraffa, Claudia Coronnello, Giuseppe Pizzolanti, Riccardo Alessandro, Alice Conigliaro

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)

Subject Terms: lncH19, Colorectal cancer, Alternative splicing, RNA-binding proteins, RBFOX2, RAC1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/5e75b0753e9f45829cad50015d076f95

Injective hydrogel loaded with liposomes-encapsulated MY-1 promotes wound healing and increases tensile strength by accelerating fibroblast migration via the PI3K/AKT-Rac1 signaling pathway

Authors: Chunhao Zhou, Zhihai Cai, Jialiang Guo, Chengfu Li, Chenghe Qin, Juanwen Yan, Dehong Yang

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)

Subject Terms: Wound healing, Liposome, GelMA, PI3K/AKT, Rac1, Cell migration, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/f7d34daaaf36439dabc09b0801358c10

Kurarinone regulates Th17/Treg balance and ameliorates autoimmune uveitis via Rac1 inhibition

Authors: Gu, Chenyang ^{a, 1}, Liu, Yidan ^{a, 1}, Lv, Jianjie ^{a, 1}, Zhang, Chun ^{b, 1}, Huang, Zhaohao ^{a, 1}, Jiang, Qi ^{a, 1}, Gao, Yuehan ^a, Tao, Tianyu ^a, Su, Yuhan ^{a, c}, Chen, Binyao ^a, Jia, Renbing ^d, Liu, Xiuxing ^{a, ⁎}, Su, Wenru ^{a, ⁎}

Source: In Journal of Advanced Research March 2025 69:381-398

Dedicator of cytokinesis protein 2 activates the epithelial–mesenchymal transition in renal fibrosis through the Rac1/PI3K/AKT pathway

Authors: Jia, Yuanyuan ^a, Sun, Jing ^a, Chen, Sha ^a, Bian, Yu ^a, Jiang, Anni ^a, Liang, Haihai ^{a, b, ⁎}, Du, Xuanyi ^{a, ⁎⁎}

Source: In BBA - Molecular Cell Research February 2025 1872(2)

Depletion of the Rho GTPases Cdc42, Rac1 or RhoA reduces PDGF-induced STAT1 and STAT3 signaling

Authors: Erik Wåhlén, Johan Lennartsson, Johan Heldin

Source: Biochemistry and Biophysics Reports, Vol 40, Iss , Pp 101828- (2024)

Subject Terms: PDGFR, Cdc42, Rac1, RhoA, Rho GTPases, STAT, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405580824001924; https://doaj.org/toc/2405-5808

Access URL: https://doaj.org/article/0ead78c0dd9f4c8dab4a3183a22ef1f2

Irisin mitigates salt-sensitive hypertension via regulating renal AMPK-Rac1 pathway

Authors: Jie Mao, Xiaocui Zhang, Chunxiang Wang, Suying Peng

Source: Clinical and Experimental Hypertension, Vol 46, Iss 1 (2024)

Subject Terms: Irisin, salt-sensitive hypertension, RAC1, aldosterone receptor, AMPK, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1064-1963; https://doaj.org/toc/1525-6006

Access URL: https://doaj.org/article/5c9b33bc083f45dd87c9422b42df669b