Acceptability of an annual tenofovir alafenamide implant for HIV prevention in South African women: findings from the CAPRISA 018 Phase I clinical trial

Authors: Tanuja N. Gengiah, Craig J. Heck, Lara Lewis, Leila E. Mansoor, Ishana Harkoo, Nqobile Myeni, Marc M. Baum, John A. Moss, James F. Rooney, Catherine Hankins, Bruno Pozzetto, Salim S. Abdool Karim, Quarraisha Abdool Karim

Source: Journal of the International AIDS Society, Vol 28, Iss 2, Pp n/a-n/a (2025)

Subject Terms: acceptability, clinical trial, HIV prevention, implant, PrEP, tenofovir alafenamide, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1758-2652

Access URL: https://doaj.org/article/dea5e811c1974acbb0cb62f4f89a195b

Evaluating diagnostic accuracy of an RT-PCR test for the detection of SARS-CoV-2 in saliva

Authors: Natasha Samsunder, Aida Sivro, Razia Hassan-Moosa, Lara Lewis, Zahra Kara, Cheryl Baxter, Quarraisha Abdool Karim, Salim Abdool Karim, Ayesha B. M. Kharsany, Kogieleum Naidoo, Sinaye Ngcapu

Source: Diagnostic and Prognostic Research, Vol 8, Iss 1, Pp 1-5 (2024)

Subject Terms: COVID-19, SARS-CoV-2, Saliva, Nasopharyngeal swab, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2397-7523

Access URL: https://doaj.org/article/17205c6b0b3e41e38e9d6a534eae2c71

Circulating immunoglobulins and transient lymphocytopenia in a sub-study of CAPRISA 012B, testing HIV monoclonal antibodies in a phase 1 trial

Authors: Parveen Sobia, Sharana Mahomed, Aida Sivro, Stephane Paul, Farzana Osman, Ishana Harkoo, Nigel Garrett, Quarraisha Abdool Karim, Salim S. Abdool Karim, Derseree Archary

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e5979693daf14179af63a736438522fe

The audacious goal to end AIDS by 2030: aspiration or reality?

Authors: Quarraisha Abdool Karim, Kenneth H. Mayer, Jivanka Mohan, Carlos delRio

Source: Journal of the International AIDS Society, Vol 27, Iss 7, Pp n/a-n/a (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1758-2652

Access URL: https://doaj.org/article/514dc9213ab0495485aaeb78381b7baa

Clearance of persistent SARS-CoV-2 associates with increased neutralizing antibodies in advanced HIV disease post-ART initiation

Authors: Farina Karim, Catherine Riou, Mallory Bernstein, Zesuliwe Jule, Gila Lustig, Strauss van Graan, Roanne S. Keeton, Janine-Lee Upton, Yashica Ganga, Khadija Khan, Kajal Reedoy, Matilda Mazibuko, Katya Govender, Kershnee Thambu, Nokuthula Ngcobo, Elizabeth Venter, Zanele Makhado, Willem Hanekom, Anne von Gottberg, Monjurul Hoque, Quarraisha Abdool Karim, Salim S. Abdool Karim, Nithendra Manickchund, Nombulelo Magula, Bernadett I. Gosnell, Richard J. Lessells, Penny L. Moore, Wendy A. Burgers, Tulio de Oliveira, Mahomed-Yunus S. Moosa, Alex Sigal

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cf97d17abeb74e59ba27f92ef737342a

Evolution and neutralization escape of the SARS-CoV-2 BA.2.86 subvariant

Authors: Khadija Khan, Gila Lustig, Cornelius Römer, Kajal Reedoy, Zesuliwe Jule, Farina Karim, Yashica Ganga, Mallory Bernstein, Zainab Baig, Laurelle Jackson, Boitshoko Mahlangu, Anele Mnguni, Ayanda Nzimande, Nadine Stock, Dikeledi Kekana, Buhle Ntozini, Cindy van Deventer, Terry Marshall, Nithendra Manickchund, Bernadett I. Gosnell, Richard J. Lessells, Quarraisha Abdool Karim, Salim S. Abdool Karim, Mahomed-Yunus S. Moosa, Tulio de Oliveira, Anne von Gottberg, Nicole Wolter, Richard A. Neher, Alex Sigal

Source: Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/385191ebb6d244fb85921e20444d30a5

Field evaluations of four SARS-CoV-2 rapid antigen tests during SARS-CoV-2 Delta variant wave in South Africa

Authors: Natasha Samsunder, Gila Lustig, Slindile Ngubane, Thando Glory Maseko, Santhuri Rambaran, Sinaye Ngcapu, Stanley Nzuzo Magini, Lara Lewis, Cherie Cawood, Ayesha B. M. Kharsany, Quarraisha Abdool Karim, Salim Abdool Karim, Kogieleum Naidoo, Aida Sivro

Source: Diagnostic and Prognostic Research, Vol 7, Iss 1, Pp 1-6 (2023)

Subject Terms: COVID-19, SARS-CoV-2, Antigen rapid diagnostic test, Performance evaluation, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2397-7523

Access URL: https://doaj.org/article/505b48ee824d48f691d115c05059f399

Hoosen (Jerry) M. Coovadia (1940–2023): Caring paediatrician, excellent scientist, courageous human rights activist and visionary leader

Authors: Quarraisha Abdool Karim

Source: South African Journal of Science, Vol 120, Iss 3/4 (2024)

Subject Terms: Science, Science (General), Q1-390, Social Sciences, Social sciences (General), H1-99

File Description: electronic resource

Relation: https://sajs.co.za/article/view/17475; https://doaj.org/toc/1996-7489

Access URL: https://doaj.org/article/6d31347665094bc0a58591f751d8d233

Extended safety and tolerability of subcutaneous CAP256V2LS and VRC07-523LS in HIV-negative women: study protocol for the randomised, placebo-controlled double-blinded, phase 2 CAPRISA 012C trial

Authors: Nigel Garrett, Farzana Osman, Sharana Mahomed, Edmund Capparelli, Nonhlanhla Yende Zuma, Derseree Archary, Penny Moore, Natasha Samsunder, Lynn Morris, Salim Abdool Karim, Catherine Hankins, Carolyn Williamson, Bruno Pozzetto, Kevin Carlton, Richard A Koup, Quarraisha Abdool Karim, Leila Mansoor, Tanuja Narayansamy Gengiah, Ishana Harkoo, Precious Radebe, Izukanji T Sikazwe, Disebo Potloane, Nqobile Myeni, Lucio Gama, Sandeep Narpala, Leonid Serebryannyy, Nicole Doria-Rose

Source: BMJ Open, Vol 13, Iss 8 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/13/8/e076843.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/88fe366c8a104a4da061d0ee7548e10d

Vaginal microbial shifts are unaffected by oral pre-exposure prophylaxis in South African women

Authors: Noluthando Mazibuko-Motau, Parveen Sobia, Jiawu Xu, Joseph Ahmed Elsherbini, James E. San, Lara Lewis, Andile Mtshali, Gugulethu Mzobe, Lungelo Ntuli, Salim S. Abdool Karim, Leila E. Mansoor, Quarraisha Abdool Karim, Douglas S. Kwon, Derseree Archary, Sinaye Ngcapu

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/730844e2c43348088bc74be162787c18

Omicron BA.4/BA.5 escape neutralizing immunity elicited by BA.1 infection

Authors: Khadija Khan, Farina Karim, Yashica Ganga, Mallory Bernstein, Zesuliwe Jule, Kajal Reedoy, Sandile Cele, Gila Lustig, Daniel Amoako, Nicole Wolter, Natasha Samsunder, Aida Sivro, James Emmanuel San, Jennifer Giandhari, Houriiyah Tegally, Sureshnee Pillay, Yeshnee Naidoo, Matilda Mazibuko, Yoliswa Miya, Nokuthula Ngcobo, Nithendra Manickchund, Nombulelo Magula, Quarraisha Abdool Karim, Anne von Gottberg, Salim S. Abdool Karim, Willem Hanekom, Bernadett I. Gosnell, COMMIT-KZN Team, Richard J. Lessells, Tulio de Oliveira, Mahomed-Yunus S. Moosa, Alex Sigal

Source: Nature Communications, Vol 13, Iss 1, Pp 1-7 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e33f1969012c445a9979f3a62e870904

Pre-infection plasma cytokines and chemokines as predictors of HIV disease progression

Authors: Samukelisiwe Ngcobo, Refilwe P. Molatlhegi, Farzana Osman, Sinaye Ngcapu, Natasha Samsunder, Nigel J. Garrett, Salim S. Abdool Karim, Quarraisha Abdool Karim, Lyle R. McKinnon, Aida Sivro

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/a3b88a3bf4264f67b7a7f5f64236e8c0

Leveraging the HIV response to strengthen pandemic preparedness

Authors: Chris Collins, Michael T. Isbell, Quarraisha Abdool Karim, Annette H. Sohn, Chris Beyrer, Allan Maleche

Source: PLOS Global Public Health, Vol 3, Iss 1 (2023)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021388/?tool=EBI; https://doaj.org/toc/2767-3375

Access URL: https://doaj.org/article/a43ac3a02266462eb914e736c21f1690

Higher mucosal antibody concentrations in women with genital tract inflammation

Authors: Parveen Sobia, Thevani Pillay, Lenine J. P. Liebenberg, Aida Sivro, Leila E. Mansoor, Farzana Osman, Jo-Ann S. Passmore, Quarraisha Abdool Karim, Salim S. Abdool Karim, Cheryl Baxter, Lyle R. McKinnon, Derseree Archary

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/7093f0217a684180845d9812855678a0

Women for science and science for women: Gaps, challenges and opportunities towards optimizing pre-exposure prophylaxis for HIV-1 prevention

Authors: Quarraisha Abdool Karim, Derseree Archary, Françoise Barré-Sinoussi, Kristina Broliden, Cecilia Cabrera, Francesca Chiodi, Sarah J. Fidler, Tanuja N. Gengiah, Carolina Herrera, Ayesha B. M. Kharsany, Lenine J. P. Liebenberg, Sharana Mahomed, Elisabeth Menu, Christiane Moog, Gabriella Scarlatti, Nabila Seddiki, Aida Sivro, Mariangela Cavarelli

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: HIV, women, prevention, gender equity, PrEP, mucosal transmission, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1055042/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/cef9e2df042648619810a33d846c7577

HIV prevention for the next decade: Appropriate, person-centred, prioritised, effective, combination prevention.

Authors: Peter Godfrey-Faussett, Luisa Frescura, Quarraisha Abdool Karim, Michaela Clayton, Peter D Ghys, (on behalf of the 2025 prevention targets working group)

Source: PLoS Medicine, Vol 19, Iss 9, p e1004102 (2022)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/a3ac9770592446a69c9ff4823b92ec02

Importance of early identification of PrEP breakthrough infections in a generalized HIV epidemic: a case report from a PrEP demonstration project in South Africa

Authors: Cherise L. Naicker, Leila E. Mansoor, Halima Dawood, Kogieleum Naidoo, Denzhe Singo, David Matten, Carolyn Williamson, Quarraisha Abdool Karim

Source: BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-6 (2020)

Subject Terms: HIV prevention, Pre-exposure prophylaxis (PrEP), Tenofovir, PrEP breakthrough infections in HIV-endemic settings, Fourth-generation rapid tests for HIV screening, HIV drug resistance, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12879-020-05255-5; https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/42f41f7953fb4786b3d502849c903ee8

CAPRISA 018: a phase I/II clinical trial study protocol to assess the safety, acceptability, tolerability and pharmacokinetics of a sustained-release tenofovir alafenamide subdermal implant for HIV prevention in women

Authors: Cheryl Baxter, Nonhlanhla Yende Zuma, Natasha Samsunder, Salim Abdool Karim, Catherine Hankins, Quarraisha Abdool Karim, Bruno Pozzetto, Leila Mansoor, Tanuja Narayansamy Gengiah, Ishana Harkoo, Precious Radebe, B Maharaj, Marc M Baum, John A Moss

Source: BMJ Open, Vol 12, Iss 1 (2022)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/12/1/e052880.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/27539166663e4cdd94f4ddd64dbb99c3

Implants for HIV prevention in young women: Provider perceptions and lessons learned from contraceptive implant provision.

Authors: Hilton Humphries, Michele Upfold, Gethwana Mahlase, Makhosazana Mdladla, Tanuja N Gengiah, Quarraisha Abdool Karim

Source: PLoS ONE, Vol 17, Iss 1, p e0262043 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/8df8f18a1395411e98719cadb6d7f051

Build on HIV investments for future pandemic preparedness

Authors: Chris Beyrer, Quarraisha Abdool Karim, Jirair Ratevosian, Chris Collins, Michael T Isbell, Allan Maleche, Annette H Sohn

Source: BMJ Global Health, Vol 6, Iss 12 (2021)

Subject Terms: Medicine (General), R5-920, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://gh.bmj.com/content/6/12/e007980.full; https://doaj.org/toc/2059-7908

Access URL: https://doaj.org/article/425bee1aa760498d9e9cc050baea7902