SARS-CoV-2 induces cardiomyocyte apoptosis and inflammation but can be ameliorated by ACE inhibitor Captopril

Authors: Huang, Xiaohan, Fan, Wenxia, Sun, Jing, Yang, Jiaqing, Zhang, Yanjun, Wang, Qian, Li, Pingchao, Zhang, Yudi, Zhang, Shengnan, Li, Heying, Wang, Jianhua, Feng, Liqiang, Zhao, Jincun, Chen, Ling, Qu, Linbing

Source: In Antiviral Research July 2023 215

An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape.

Authors: Deng, Weiqi, Niu, Xuefeng, He, Ping, Yan, Qihong, Liang, Huan, Wang, Yongping, Ning, Lishan, Lin, Zihan, Zhang, Yudi, Zhao, Xinwei, Feng, Liqiang, Qu, Linbing, Chen, Ling

Source: Frontiers in Immunology; 2025, p1-15, 15p

Subject Terms: IMMUNOGLOBULIN heavy chains, IMMUNE complexes, AMINO acid residues, HUMORAL immunity, POPULATION genetics

Germline IGHV3-53-encoded RBD-targeting neutralizing antibodies are commonly present in the antibody repertoires of COVID-19 patients

Authors: Yan, Qihong, He, Ping, Huang, Xiaohan, Luo, Kun, Zhang, Yudi, Yi, Haisu, Wang, Qian, Li, Feng, Hou, Ruitian, Fan, Xiaodi, Li, Pingchao, Liu, Xinglong, Liang, Huan, Deng, Yijun, Chen, Zhaoming, Chen, Yunfei, Mo, Xiaoneng, Feng, Liqiang, Xiong, Xiaoli, Li, Song, Han, Jian, Qu, Linbing, Niu, Xuefeng, Chen, Ling

Source: Emerging microbes & infections. 10(1):1097-1111

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140633315.0x000001&indx=1&recIds=ETOCvdc_100140633315.0x000001

A single-dose circular RNA vaccine prevents Zika virus infection without enhancing dengue severity in mice.

Authors: Liu, Xinglong, Li, Zhengfeng, Li, Xiaoxia, Wu, Weixuan, Jiang, Huadong, Zheng, Yufen, Zhou, Junjie, Ye, Xianmiao, Lu, Junnan, Wang, Wei, Yu, Lei, Li, Yiping, Qu, Linbing, Wang, Jianhua, Li, Feng, Chen, Ling, Wu, Linping, Feng, Liqiang

Source: Nature Communications; 10/16/2024, Vol. 15 Issue 1, p1-19, 19p

Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques

Authors: Li, Pingchao, Wang, Qian, He, Yizi, Yang, Chenchen, Zhang, Zhengyuan, Liu, Zijian, Liu, Bo, Yin, Li, Cui, Yilan, Hu, Peiyu, Liu, Yichu, Zheng, Pingqian, Wang, Wei, Qu, Linbing, Sun, Caijun, Guan, Suhua, Feng, Liqiang, Chen, Ling

Source: Emerging microbes & infections. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193509471.0x000001&indx=1&recIds=ETOCvdc_100193509471.0x000001

Chloroquine inhibits endosomal viral RNA release and autophagy-dependent viral replication and effectively prevents maternal to fetal transmission of Zika virus

Authors: Zhang, Shengnan, Yi, Changhua, Li, Chufang, Zhang, Fan, Peng, Jiaojiao, Wang, Qian, Liu, Xinglong, Ye, Xianmiao, Li, Pingchao, Wu, Min, Yan, Qihong, Guo, Wenjing, Niu, Xuefeng, Feng, Liqiang, Pan, Weiqi, Chen, Ling, Qu, Linbing

Source: In Antiviral Research September 2019 169

Longitudinal analysis of the antibody repertoire of a Zika virus-infected patient revealed dynamic changes in antibody response

Authors: Niu, Xuefeng, Yan, Qihong, Yao, Zhipeng, Zhang, Fan, Qu, Linbing, Wang, Chunlin, Wang, Chengrui, Lei, Hui, Chen, Chaoming, Liang, Renshan, Luo, Jia, Wang, Qian, Zhao, Lingzhai, Zhang, Yudi, Luo, Kun, Wang, Longyu, Wu, Hongkai, Liu, Tingting, Li, Pingchao, Zheng, Zhiqiang, Tan, Yee Joo, Feng, Liqiang, Zhang, Zhenhai, Han, Jian, Zhang, Fuchun, Chen, Ling

Source: Emerging microbes & infections. 9(1):111-123

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117718240.0x000001&indx=1&recIds=ETOCvdc_100117718240.0x000001

Intranasal adenovirus-vectored Omicron vaccine induced nasal immunoglobulin A has superior neutralizing potency than serum antibodies.

Authors: Chen, Si, Zhang, Zhengyuan, Wang, Qian, Yang, Qi, Yin, Li, Ning, Lishan, Chen, Zhilong, Tang, Jielin, Deng, Weiqi, He, Ping, Li, Hengchun, Shi, Linjing, Deng, Yijun, Liu, Zijian, Bu, Hemeng, Zhu, Yaohui, Liu, Wenming, Qu, Linbing, Feng, Liqiang, Xiong, Xiaoli

Source: Signal Transduction & Targeted Therapy; 7/22/2024, Vol. 9 Issue 1, p1-12, 12p

Convalescent patient-derived monoclonal antibodies targeting different epitopes of E protein confer protection against Zika virus in a neonatal mouse model

Authors: Niu, Xuefeng, Zhao, Lingzhai, Qu, Linbing, Yao, Zhipeng, Zhang, Fan, Yan, Qihong, Zhang, Shengnan, Liang, Renshan, Chen, Peihai, Luo, Jia, Xu, Wei, Lv, Huibin, Liu, Xinglong, Lei, Hui, Yi, Changhua, Li, Pingchao, Wang, Qian, Wang, Yang, Yu, Lei, Zhang, Xiaoyan, Bryan, L. Aubrey, Davidson, Edgar, Doranz, j. Benjamin, Feng, Liqiang, Pan, Weiqi, Zhang, Fuchun, Chen, Ling

Source: Emerging microbes & infections. 8(1):749-759

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094548112.0x000001&indx=1&recIds=ETOCvdc_100094548112.0x000001

PLA2G12A protects against diet‐induced obesity and insulin resistance by enhancing energy expenditure and clearance of circulating triglycerides.

Authors: Wu, Min, Wang, Qian, Li, Hengchun, Tao, Jiawang, Wang, Zhi, Zhang, Shengnan, Chen, Longhui, Li, Pingchao, Chen, Ling, Qu, Linbing

Source: FASEB Journal; May2024, Vol. 38 Issue 9, p1-15, 15p

An adenovirus serotype 2-vectored ebolavirus vaccine generates robust antibody and cell-mediated immune responses in mice and rhesus macaques

Authors: Feng, Yupeng, Li, Chufang, Hu, Peiyu, Wang, Qian, Zheng, Xuehua, Zhao, Yongkun, Shi, Yi, Yang, Songtao, Yi, Changhua, Feng, Ying, Wu, Chunxiu, Qu, Linbing, Xu, Wei, Li, Yao, Sun, Caijun, Gao, Fu Geroge, Xia, Xianzhu, Feng, Liqiang, Chen, Ling

Source: Emerging microbes & infections. 7(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100104082582.0x000001&indx=1&recIds=ETOCvdc_100104082582.0x000001

Incorporation of NS1 and prM/M are important to confer effective protection of adenovirus-vectored Zika virus vaccine carrying E protein

Authors: Liu, Xinglong, Qu, Linbing, Ye, Xianmiao, Yi, Changhua, Zheng, Xuehua, Hao, Mingli, Su, Wan, Yao, Zhipeng, Chen, Peihai, Zhang, Shengnan, Feng, Yupeng, Wang, Qian, Yan, Qihong, Li, Pingchao, Li, Heying, Li, Feng, Pan, Weiqi, Niu, Xuefeng, Xu, Ruian, Feng, Liqiang, Chen, Ling

Source: Npj vaccines. 3:1-8

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175390968.0x000001&indx=1&recIds=ETOCvdc_100175390968.0x000001

Structural basis for functional selectivity and ligand recognition revealed by crystal structures of human secreted phospholipase A2 group IIE

Authors: Hou, Shulin, Xu, Tingting, Xu, Jinxin, Qu, Linbing, Xu, Yong, Chen, Ling, Liu, Jinsong

Source: Scientific reports. 7(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179711134.0x000001&indx=1&recIds=ETOCvdc_100179711134.0x000001

ERRγ-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element

Authors: Zhen, Xuhui, Gan, Qingqing, Qu, Linbing, Dong, Yan, Pan, Chen, Liu, Jinsong, Wang, Na, Xu, Tingting

Source: In Biochemical and Biophysical Research Communications 14 May 2023 656:16-22

Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARS-CoV-2 variants.

Authors: Wang, Qian, Yang, Chenchen, Yin, Li, Sun, Jing, Wang, Wei, Li, Hengchun, Zhang, Zhengyuan, Chen, Si, Liu, Bo, Liu, Zijian, Shi, Linjing, Liu, Xiaolin, Guan, Suhua, Wang, Chunhua, Qu, Linbing, Feng, Ying, Niu, Xuefeng, Feng, Liqiang, Zhao, Jincun, Li, Pingchao

Source: Signal Transduction & Targeted Therapy; 4/17/2023, Vol. 8 Issue 1, p1-9, 9p

Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients.

Authors: Niu, Xuefeng, Li, Song, Li, Pingchao, Pan, Wenjing, Wang, Qian, Feng, Ying, Mo, Xiaoneng, Yan, Qihong, Ye, Xianmiao, Luo, Jia, Qu, Linbing, Weber, Daniel, Byrne-Steele, Miranda L., Wang, Zhe, Yu, Fengjia, Li, Fang, Myers, Richard M., Lotze, Michael T., Zhong, Nanshan, Han, Jian

Source: Frontiers in Immunology; 9/30/2020, Vol. 11, pN.PAG-N.PAG, 9p

Subject Terms: B cell receptors, T cell receptors, COVID-19, IMMUNE response, VIRUS diseases

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Correction To: Intranasal booster using an Omicron vaccine confers broad mucosal and systemic immunity against SARS-CoV-2 variants.

Authors: Wang, Qian, Yang, Chenchen, Yin, Li, Sun, Jing, Wang, Wei, Li, Hengchun, Zhang, Zhengyuan, Chen, Si, Liu, Bo, Liu, Zijian, Shi, Linjing, Liu, Xiaolin, Guan, Suhua, Wang, Chunhua, Qu, Linbing, Feng, Ying, Niu, Xuefeng, Feng, Liqiang, Zhao, Jincun, Li, Pingchao

Source: Signal Transduction & Targeted Therapy; 5/24/2023, Vol. 8 Issue 1, p1-1, 1p

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Group IIE secretory phospholipase A2 regulates lipolysis in adipocytes.

Authors: Zhi, Hui, Qu, Linbing, Wu, Fang, Chen, Ling, Tao, Jun

Source: Obesity (19307381); Apr2015, Vol. 23 Issue 4, p760-768, 9p

Subject Terms: PHOSPHOLIPASES, FAT cells, LIPOLYSIS, MICE physiology, TRIGLYCERIDES, GLYCERIN