Tissue‐Resident Memory CD8+ T Cells: Differentiation, Phenotypic Heterogeneity, Biological Function, Disease, and Therapy

Authors: Luming Xu, Lilin Ye, Qizhao Huang

Source: MedComm, Vol 6, Iss 3, Pp n/a-n/a (2025)

Subject Terms: autoimmune diseases, CD8+TRM, ICB therapy, infection, tumor, vaccine, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/7f2d3b40dd334968a8113ac2480cf664

A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD

Authors: Xiaofei Wang, Ao Hu, Xiangyu Chen, Yixin Zhang, Fei Yu, Shuai Yue, Arong Li, Junsong Zhang, Zhiwei Pan, Yang Yang, Yao Lin, Leiqiong Gao, Jing Zhou, Jing Zhao, Fang Li, Yaling Shi, Feng Huang, Xiaofan Yang, Yi Peng, Luoyang Tu, Huan Zhang, Huanying Zheng, Jun He, Hui Zhang, Lifan Xu, Qizhao Huang, Yongqun Zhu, Kai Deng, Lilin Ye

Source: Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/1665f69d1d014c8fabef454695b0d169

The lncRNA Snhg1-Vps13D vesicle trafficking system promotes memory CD8 T cell establishment via regulating the dual effects of IL-7 signaling

Authors: Yanyan Zhang, Baohua Li, Qiang Bai, Pengcheng Wang, Gang Wei, Zhirong Li, Li Hu, Qin Tian, Jing Zhou, Qizhao Huang, Zhiming Wang, Shuai Yue, Jialin Wu, Liuqing Yang, Xinyuan Zhou, Lubin Jiang, Ting Ni, Lilin Ye, Yuzhang Wu

Source: Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/ccb3befdc2754c018ded748254cf1d30

The dichotomous and incomplete adaptive immunity in COVID-19 patients with different disease severity

Authors: Leiqiong Gao, Jing Zhou, Sen Yang, Lisha Wang, Xiangyu Chen, Yang Yang, Ren Li, Zhiwei Pan, Jing Zhao, Zhirong Li, Qizhao Huang, Jianfang Tang, Li Hu, Pinghuang Liu, Guozhong Zhang, Yaokai Chen, Lilin Ye

Source: Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-10 (2021)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/2bcca2cbe28a4ebeb831552c3efb9f24

Tumor-Specific CD4+ T Cells Restrain Established Metastatic Melanoma by Developing Into Cytotoxic CD4– T Cells

Authors: Qiao Liu, Lisha Wang, Huayu Lin, Zhiming Wang, Jialin Wu, Junyi Guo, Shuqiong Wen, Ling Ran, Zhengliang Yue, Xingxing Su, Qing Wu, Jianfang Tang, Zhirong Li, Li Hu, Lifan Xu, Lilin Ye, Qizhao Huang

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: tumor specific, CD4+T cells, CD4-T cells, metastasis, melanoma, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.875718/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5ff83e5054d4437889eaa6d509215c76

CD4+ T-cell epitope-based heterologous prime-boost vaccination potentiates anti-tumor immunity and PD-1/PD-L1 immunotherapy

Authors: Xiangyu Chen, Cheng Chen, Jun Huang, Wei Yao, Yanyan Zhang, Pengcheng Wang, Qing Wu, Lisha Wang, Yuan Luo, Zhiming Wang, Minglu Xiao, Luoyingzi Xie, Guoshuai Cao, Shun Lei, Zhengping Wei, Jingyi Fang, Xingxing Yang, Qizhao Huang, Lifan Xu, Junyi Guo, Shuqiong Wen, Jianfang Tang, Jianqiang Ye, Ran He, Lilin Ye

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 5 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/5/e004022.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/f454421926124580be6c11f04ef36430

Differential expression of inhibitory receptor NKG2A distinguishes disease‐specific exhausted CD8+ T cells

Authors: Xiangyu Chen, Yao Lin, Shuai Yue, Yang Yang, Xinxin Wang, Zhiwei Pan, Xiaofan Yang, Leiqiong Gao, Jing Zhou, Zhirong Li, Li Hu, Jianfang Tang, Qing Wu, Yifei Wang, Qin Tian, Yaxing Hao, Lifan Xu, Bo Zhu, Qizhao Huang, Lilin Ye

Source: MedComm, Vol 3, Iss 1, Pp n/a-n/a (2022)

Subject Terms: cancer immunotherapy, chronic viral infection, NKG2A, T cell exhaustion, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/38ed27414d70460a9581234169f86350

Sensitivity of SARS-CoV-2 Variants to Neutralization by Convalescent Sera and a VH3-30 Monoclonal Antibody

Authors: Shuai Yue, Zhirong Li, Yao Lin, Yang Yang, Mengqi Yuan, Zhiwei Pan, Li Hu, Leiqiong Gao, Jing Zhou, Jianfang Tang, Yifei Wang, Qin Tian, Yaxing Hao, Juan Wang, Qizhao Huang, Lifan Xu, Bo Zhu, Pinghuang Liu, Kai Deng, Li Wang, Lilin Ye, Xiangyu Chen

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: COVID-19, SARS-CoV-2 variants, neutralizing mAb, convalescent sera, antibody response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.751584/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ba267ab4930942aba133f252798a65a1

Bcl6 Preserves the Suppressive Function of Regulatory T Cells During Tumorigenesis

Authors: Yiding Li, Zhiming Wang, Huayu Lin, Lisha Wang, Xiangyu Chen, Qiao Liu, Qianfei Zuo, Jianjun Hu, Haoqiang Wang, Junyi Guo, Luoyingzi Xie, Jianfang Tang, Zhirong Li, Li Hu, Litian Xu, Xinyuan Zhou, Lilin Ye, Qizhao Huang, Lifan Xu

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: Bcl6, Treg, tumorigenesis, checkpoint blockade therapy, anti-tumor immunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00806/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2646097ec8d24696adbdde1672fd045f

The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection

Authors: Pengcheng Wang, Youping Wang, Luoyingzi Xie, Minglu Xiao, Jialin Wu, Lifan Xu, Qiang Bai, Yaxing Hao, Qizhao Huang, Xiangyu Chen, Ran He, Baohua Li, Sen Yang, Yaokai Chen, Yuzhang Wu, Lilin Ye

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: T-bet, follicular helper T cells, type I immune response, humoral response, T cell differentiation, transcriptional regulation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00606/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e2e3f37e63d646dbac2842d339ed57e5

The Transcription Factor TCF1 Preserves the Effector Function of Exhausted CD8 T Cells During Chronic Viral Infection

Authors: Yifei Wang, Jianjun Hu, Yiding Li, Minglu Xiao, Haoqiang Wang, Qin Tian, Zhirong Li, Jianfang Tang, Li Hu, Yan Tan, Xinyuan Zhou, Ran He, Yuzhang Wu, Lilin Ye, Zhinan Yin, Qizhao Huang, Lifan Xu

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: TCF1, CD8 T cell, exhaustion, LCMV, chronic viral infection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00169/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/609f7392abb545a3a422ef9fc8e8eeed

Molecular Basis of the Differentiation and Function of Virus Specific Follicular Helper CD4+ T Cells

Authors: Qizhao Huang, Jianjun Hu, Jianfang Tang, Lifan Xu, Lilin Ye

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: follicular T helper cells, acute viral infection, chronic viral infection, differentiation, CD4 T cells +, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00249/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a6395b60eedf4ddab6fbe3750c272cc6

FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.

Authors: Siru Zhou, Yangli Xie, Junzhou Tang, Junlan Huang, Qizhao Huang, Wei Xu, Zuqiang Wang, Fengtao Luo, Quan Wang, Hangang Chen, Xiaolan Du, Yue Shen, Di Chen, Lin Chen

Source: PLoS Genetics, Vol 11, Iss 6, p e1005214 (2015)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4474636?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/217dd1a27c524cf593f6603b07396790

Draining Lymph Node Metastasis Model for Assessing the Dynamics of Antigen-Specific CD8+ T Cells During Tumorigenesis

Authors: Yan Zhang, author¹, Xingxing Su, author², Lisha Wang, author², Zhengliang Yue, author², Qiao Liu, author³, Ling Ran, author², Shun Lei, author², Jianjun Hu, author², Lifan Xu, author², Lilin Ye, author², Ping Ji, author⁴, Guimei Li, author¹, Qizhao Huang, author⁵, Shuqiong Wen, author⁴

Source: Journal of Visualized Experiments. (203)

Availability: http://www.jove.com/video/65646

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Authors: Lisha Wang, author¹, Zhiming Wang, author¹, Junyi Guo, author², Huayu Lin, author¹, Shuqiong Wen, author², Qiao Liu, author¹, Yiding Li, author³, Qing Wu, author¹, Leiqiong Gao, author¹, Xiangyu Chen, author¹, Luoyingzi Xie, author¹, Qin Tian, author¹, Jianfang Tang, author¹, Zhirong Li, author¹, Li Hu, author¹, Juan Wang, author⁴, Lifan Xu, author¹, Qizhao Huang, author⁵, Lilin Ye, author¹

Source: Journal of Visualized Experiments. (172)

Availability: http://www.jove.com/video/62442

Chapter Six - T cell immune response within B-cell follicles.

Authors: Qizhao Huang, Lifan Xu, Lilin Ye

Source: Advances in Immunology; 2019, Vol. 144, p155-171, 17p

Subject Terms: T cells, T helper cells, CYTOTOXIC T cells, SUPPRESSOR cells, IMMUNE response

Redox-assisted Li+-storage in lithium-ion batteries.

Authors: Qizhao Huang¹, Qing Wang^1,2 msewq@nus.edu.sg

Source: Chinese Physics B. Jan2016, Vol. 25 Issue 1, p1-1. 1p.

Subject Terms: *OXIDATION-reduction reaction, *LITHIUM ions, *NANOWIRES, *FRONTIER orbitals, *PHOTOELECTRON spectroscopy, *CHARGE transfer

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