Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells

Authors: Wentao Pan, Qiuyun Luo, Eric Liang, Mude Shi, Jian Sun, Huimin Shen, Zhenhai Lu, Lin Zhang, Xianglei Yan, Luping Yuan, Suna Zhou, Hanjie Yi, Yifan Zhai, Miao-zhen Qiu, Dajun Yang

Source: Cancer Cell International, Vol 24, Iss 1, Pp 1-13 (2024)

Subject Terms: Smac mimetic, APG-1387, Combination therapy, Immunotherapy, CD3 + NK1.1 + cells, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/351b402f688449ceb4c6ca9f401e8dfc

Bcl‐2/Bcl‐xl inhibitor APG‐1252‐M1 is a promising therapeutic strategy for gastric carcinoma

Authors: Hanjie Yi, Miao‐Zhen Qiu, Luping Yuan, Qiuyun Luo, Wentao Pan, Suna Zhou, Lin Zhang, Xianglei Yan, Da‐Jun Yang

Source: Cancer Medicine, Vol 9, Iss 12, Pp 4197-4206 (2020)

Subject Terms: APG‐1252‐M1, apoptosis, Bcl‐2/Bcl‐xl inhibitor, gastric cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/6d3d315277894e3ab1c21328cee0f491

A novel small molecule inhibitor of MDM2-p53 (APG-115) enhances radiosensitivity of gastric adenocarcinoma

Authors: Hanjie Yi, Xianglei Yan, Qiuyun Luo, Luping Yuan, Baoxia Li, Wentao Pan, Lin Zhang, Haibo Chen, Jing Wang, Yubin Zhang, Yifan Zhai, Miao-Zhen Qiu, Da-Jun Yang

Source: Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-10 (2018)

Subject Terms: Small molecule inhibitors, MDM2, p53, Gastric cancer, Radiation, Apoptosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13046-018-0765-8; https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/741ca8ab6c9e4e2bb0e4bb81ca774357

Prognostic impact of acellular mucin pools towards the patients with locally advanced rectal cancer achieving pathological complete response after preoperative chemoradiotherapy

Authors: Lin Zhang, Huajie Guan, Qiuyun Luo, Lifang Yuan, Yulan Mao, Xiaojun Wu, Zhizhong Pan, Junzhong Lin, Jianhong Peng

Source: Therapeutic Advances in Gastroenterology, Vol 13 (2020)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/5a4334fc79344564a144f28de0e4f076

Fasting insulin, insulin resistance, and risk of cardiovascular or all-cause mortality in non-diabetic adults: a meta-analysis.

Authors: Xiaohong Zhang, Jun Li, Shuiping Zheng, Qiuyun Luo, Chunmei Zhou, Chaoyang Wang

Source: Bioscience Reports; Oct2017, Vol. 37 Issue 5, p1-7, 7p

Subject Terms: CARDIOVASCULAR disease related mortality, INSULIN resistance, PEOPLE with diabetes, FASTING, HEALTH of adults, PHYSIOLOGY

APG-1252-12A induces mitochondria-dependent apoptosis through inhibiting the antiapoptotic proteins Bcl-2/Bcl-xl in HL-60 cells.

Authors: JING WANG, DAJUN YANG, QIUYUN LUO, MIAOZHEN QIU, LIN ZHANG, BAOXIA LI, HAIBO CHEN, HANJIE YI, XIANGLEI YAN, SHUXIA LI, JIAN SUN

Source: International Journal of Oncology; Aug2017, Vol. 51 Issue 2, p563-572, 10p

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