Co-delivery of PD-L1- and EGFR-targeting siRNAs by synthetic PEG12-KL4 peptide to the lungs as potential strategy against non-small cell lung cancer

Authors: Man, Rico C.H., Qiu, Yingshan, Leung, Susan W.S., Fruhwirth, Gilbert O., Lam, Jenny K.W.

Source: In European Journal of Pharmaceutics and Biopharmaceutics February 2024 195

Comparative evaluation of physical characteristics and volatile flavor components of Bangia fusco-purpurea subjected to hot air drying and vacuum freeze-drying

Authors: Wu, Jingna, Pan, Nan, Chen, Xiaoting, Shan, Debiao, Shi, Huifang, Qiu, Yingshan, Liu, Zhiyu, Su, Yongchang, Weng, Junfa

Source: In Current Research in Food Science 2023 7

Optimization of PEGylated KL4 Peptide for siRNA Delivery with Improved Pulmonary Tolerance

Authors: Qiu, Yingshan, Clarke, Maria, Wan, Leon T. L., Lo, Jason C. K., Mason, A. James, Lam, Jenny K. W.

Source: Molecular pharmaceutics. 18(6):2218-2232

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626784055&indx=1&recIds=ETOCRN626784055

Modification of KL4 Peptide Revealed the Importance of Alpha-Helical Structure for Efficient siRNA Delivery

Authors: Qiu, Yingshan, Lo, Jason C.K., Kwok, Kerry C.W., Mason, A. James, Lam, Jenny K.W.

Source: Nucleic acid therapeutics. 31(3):220-228

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164313389.0x000001&indx=1&recIds=ETOCvdc_100164313389.0x000001

Inhaled RNA Therapy: From Promise to Reality

Authors: Chow, Michael Y.T., Qiu, Yingshan, Lam, Jenny K.W.

Source: In Trends in Pharmacological Sciences October 2020 41(10):715-729

Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide

Authors: Qiu, Yingshan, Man, Rico C.H., Liao, Qiuying, Kung, Keshia L.K., Chow, Michael Y.T., Lam, Jenny K.W. ^*

Source: In Journal of Controlled Release 28 November 2019 314:102-115

Spray freeze drying of small nucleic acids as inhaled powder for pulmonary delivery

Authors: Liang, Wanling, Chan, Alan Y.L., Chow, Michael Y.T., Lo, Fiona F.K., Qiu, Yingshan, Kwok, Philip C.L., Lam, Jenny K.W.

Source: Asian journal of pharmaceutical sciences. 13(2):163-172

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100056327894.0x000001&indx=1&recIds=ETOCvdc_100056327894.0x000001

Inhaled Dry Powder Formulation of Tamibarotene, a Broad‐Spectrum Antiviral against Respiratory Viruses Including SARS‐CoV‐2 and Influenza Virus

Authors: Liao, Qiuying, Yuan, Shuofeng, Cao, Jianli, Tang, Kaiming, Qiu, Yingshan, Seow, Han Cong, Man, Rico Chi‐Hang, Shao, Zitong, Huang, Yaoqiang, Liang, Ronghui, Chan, Jasper Fuk‐Woo, Yuen, Kwok‐Yung, Lam, Jenny Ka‐Wing

Source: Advanced therapeutics. 4(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123593602.0x000001&indx=1&recIds=ETOCvdc_100123593602.0x000001

Inhaled powder formulation of naked siRNA using spray drying technology with l-leucine as dispersion enhancer

Authors: Chow, Michael Y.T., Qiu, Yingshan, Lo, Fiona F.K., Lin, Hinson H.S., Chan, Hak-Kim, Kwok, Philip C.L., Lam, Jenny K.W.

Source: International journal of pharmaceutics. 530(1/2):40-52

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100063593229.0x000001&indx=1&recIds=ETOCvdc_100063593229.0x000001

From Pulmonary Surfactant, Synthetic KL4 Peptide as Effective siRNA Delivery Vector for Pulmonary Delivery

Authors: Qiu, Yingshan, Chow, Michael Y. T., Liang, Wanling, Chung, Winnie W. Y., Mak, Judith C. W., Lam, Jenny K. W.

Source: Molecular pharmaceutics. 14(12):4606-4617

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN614052282&indx=1&recIds=ETOCRN614052282

Incorporation of a Nuclear Localization Signal in pH Responsive LAH4-L1 Peptide Enhances Transfection and Nuclear Uptake of Plasmid DNA

Authors: Xu, Yingying, Liang, Wanling, Qiu, Yingshan, Cespi, Marco, Palmieri, Giovanni F., Mason, A. James, Lam, Jenny K. W.

Source: Molecular pharmaceutics. 13(9):3141-3152

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN609176167&indx=1&recIds=ETOCRN609176167

High siRNA loading powder for inhalation prepared by co-spray drying with human serum albumin

Authors: Chow, Michael Y.T., Qiu, Yingshan, Liao, Qiuying, Kwok, Philip C.L., Chow, Shing Fung, Chan, Hak-Kim, Lam, Jenny K.W.

Source: International journal of pharmaceutics. 572

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095999670.0x000001&indx=1&recIds=ETOCvdc_100095999670.0x000001

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