Case report and literature review: clinical manifestations and treatment of human RelA deficiency

Authors: Chenghao Wang, Wenjie Wang, Xiaoying Hui, Jia Hou, Qinhua Zhou, Qifan Li, Qi Wu, Qi Ni, Bingbing Wu, Jinqiao Sun, Xiaochuan Wang

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: RelA deficiency, NF-κB, recurrent oral ulcers, Behçet’s disease, case report, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1529654/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/ca05189ea84b41f9b03de13553517a8b

Diagnosis of mixed infection and a primary immunodeficiency disease using next-generation sequencing: a case report

Authors: Xiaolei Zhang, Yixue Wang, Daly Pen, Jing Liu, Qinhua Zhou, Yao Wang, Huaqing Zhong, Tingyan Liu, Weiming Chen, Bingbing Wu, Yang Zhou, Chuanqing Wang, Xiangyu Li, Fangyou Yu, Xiaochuan Wang, Guoping Lu, Gangfeng Yan

Source: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

Subject Terms: major histocompatibility complex class II, immunodeficiency, mycobacterium abscessus, next-generation sequencing, whole exome sequencing, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2023.1179090/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/4e9d8d3a56ec4490b37e5021e86b5640

Chromosomal abnormalities related to fever of unknown origin in a Chinese pediatric cohort and literature review

Authors: Bijun Sun, Mi Yang, Jia Hou, Wenjie Wang, Wenjing Ying, Xiaoying Hui, Qinhua Zhou, Haili Yao, Jinqiao Sun, Xiaochuan Wang

Source: Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-15 (2022)

Subject Terms: Fever of unknown origin, Chromosomal abnormalities, Copy number variations, Autoinflammatory, Central fever, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/54dd4bd28e164460acfbaf5f1bce5835

Severe G6PD deficiency leads to recurrent infections and defects in ROS production: Case report and literature review

Authors: Bijun Sun, Qifan Li, Xiaolong Dong, Jia Hou, Wenjie Wang, Wenjing Ying, Xiaoying Hui, Qinhua Zhou, Haili Yao, Jinqiao Sun, Xiaochuan Wang

Source: Frontiers in Genetics, Vol 13 (2022)

Subject Terms: G6PD gene, infection, ROS, chromosome inactivation, NF-κB pathway, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2022.1035673/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/7b642ac7d5f248fd8fb29cfe33c4c3ca

Rapid diagnosis of Talaromyces marneffei infection by metagenomic next-generation sequencing technology in a Chinese cohort of inborn errors of immunity

Authors: Lipin Liu, Bijun Sun, Wenjing Ying, Danru Liu, Ying Wang, Jinqiao Sun, Wenjie Wang, Mi Yang, Xiaoying Hui, Qinhua Zhou, Jia Hou, Xiaochuan Wang

Source: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Subject Terms: Talaromyces marneffei, metagenomic next-generation sequencing, inborn errors of immunity, IL12RB1 mutation, T-cell-mediated immunity, intrinsic and innate immunodeficiencies, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.987692/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/2c3145da55874e29b22c98946baa0fa6

Efficacy of tocilizumab therapy in a patient with severe pancytopenia associated with a STAT3 gain-of-function mutation

Authors: Wenjie Wang, Luyao Liu, Xiaoying Hui, Ying Wang, Wenjing Ying, Qinhua Zhou, Jia Hou, Mi Yang, Bijun Sun, Jinqiao Sun, Xiaochuan Wang

Source: BMC Immunology, Vol 22, Iss 1, Pp 1-9 (2021)

Subject Terms: STAT3 transcription factor, Tocilizumab, Immune Dysregulation, Gain-of-function mutations, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2172

Access URL: https://doaj.org/article/61c440be3029403faa4a07ceae0b4e4f

The clinical, immunological and genetic features of 12 Chinese patients with STAT3 mutations

Authors: Li Lin, Ying Wang, Bijun Sun, Luyao Liu, Wenjing Ying, Wenjie Wang, Qinhua Zhou, Jia Hou, Haili Yao, Liyuan Hu, Jinqiao Sun, Xiaochuan Wang

Source: Allergy, Asthma & Clinical Immunology, Vol 16, Iss 1, Pp 1-10 (2020)

Subject Terms: STAT3, Hyperimmunoglobulin E syndrome, HIES, Primary immunodeficiency disease, STAT3 deficiency, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13223-020-00462-w; https://doaj.org/toc/1710-1492

Access URL: https://doaj.org/article/429a5a35266a4a0d9f1d031b6ed6cf76

LIG4 syndrome: clinical and molecular characterization in a Chinese cohort

Authors: Bijun Sun, Qiuyu Chen, Ying Wang, Danru Liu, Jia Hou, Wenjie Wang, Wenjing Ying, Xiaoying Hui, Qinhua Zhou, Jinqiao Sun, Xiaochuan Wang

Source: Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-9 (2020)

Subject Terms: DNA ligase IV syndrome, Microcephaly, Inflammatory bowel disease, Immunodeficiency, Genetic testing, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13023-020-01411-x; https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/951dd36bd2e34a639601715eb75f17b6

Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene

Authors: Wenjie Wang, Qing Min, Nannan Lai, Krisztian Csomos, Ying Wang, Luyao Liu, Xin Meng, Jinqiao Sun, Jia Hou, Wenjing Ying, Qinhua Zhou, Bijun Sun, Xiaoying Hui, Boglarka Ujhazi, Sumai Gordon, David Buchbinder, Catharina Schuetz, Manish Butte, Jolan E. Walter, Xiaochuan Wang, Ji-Yang Wang

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: activated PI3Kδ syndrome (APDS), B cell survival and activation, CD27-IgD- double-negative B cells, Ig gene class switch recombination, plasma cell differentiation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.890073/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8c8365988a5549fb8f212dacf50ffa66

RAG1 splicing mutation causes enhanced B cell differentiation and autoantibody production

Authors: Qing Min, Xin Meng, Qinhua Zhou, Ying Wang, Yaxuan Li, Nannan Lai, Ermeng Xiong, Wenjie Wang, Shoya Yasuda, Meiping Yu, Hai Zhang, Jinqiao Sun, Xiaochuan Wang, Ji-Yang Wang

Source: JCI Insight, Vol 6, Iss 19 (2021)

Subject Terms: Autoimmunity, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/45e62efa5e7f4f46860d57d96cda425f

High-Frequency Exon Deletion of DNA Cross-Link Repair 1C Accounting for Severe Combined Immunodeficiency May Be Missed by Whole-Exome Sequencing

Authors: Feifan Xiao, Yulan Lu, Bingbing Wu, Bo Liu, Gang Li, Ping Zhang, Qinhua Zhou, Jinqiao Sun, Huijun Wang, Wenhao Zhou

Source: Frontiers in Genetics, Vol 12 (2021)

Subject Terms: severe combined immunodeficiency, DCLRE1C gene, copy number variation, single nucleotide variation, sequencing, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2021.677748/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/0cff36ccc492473e97548499929a17dc

AG1478 inhibits the migration and invasion of cisplatin-resistant human lung adenocarcinoma cells via the cell cycle regulation by matrix metalloproteinase-9.

Authors: LI MA, HUIQIN YAN, QINHUA ZHOU

Source: Oncology Letters; 2014, Vol. 8 Issue 2, p921-927, 7p

Subject Terms: CISPLATIN, CANCER invasiveness, CANCER cell migration, ADENOCARCINOMA, LUNG cancer, CELL cycle regulation, MATRIX metalloproteinases

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Pristimerin, a natural anti-tumor triterpenoid, inhibits LPS-induced TNF-α and IL-8 production through down-regulation of ROS-related classical NF-κB pathway in THP-1 cells.

Authors: Bin Hui¹, Xin Yao¹, Qinhua Zhou¹, Ziyan Wu¹, Peng Sheng², Liping Zhang³ zhanglp-sh@hotmail.com

Source: International Immunopharmacology. Aug2014, Vol. 21 Issue 2, p501-508. 8p.

Subject Terms: *ANTINEOPLASTIC agents, *TRITERPENOIDS, *PHYSIOLOGICAL effects of lipopolysaccharides, *TUMOR necrosis factors, *INTERLEUKIN-8, *REACTIVE oxygen species, *T cells