Salmonella Typhimurium derived OMV nanoparticle displaying mixed heterologous O-antigens confers immunogenicity and protection against STEC infections in mice

Authors: Xiaoping Bian, Yaolin Chen, Wenjin Zhang, Xinyu Liu, Meihong Lei, Haoxiang Yuan, Mengru Li, Qing Liu, Qingke Kong

Source: Microbial Cell Factories, Vol 24, Iss 1, Pp 1-19 (2025)

Subject Terms: OMV, STEC, O-antigen, Genetically engineered Salmonella, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2859

Access URL: https://doaj.org/article/b0a672010b78445293c7eb1f7a797973

Lipid A-modified Escherichia coli can produce porcine parvovirus virus-like particles with high immunogenicity and minimal endotoxin activity

Authors: Xuegang Shen, Yong-Bo Yang, Yanfei Gao, Shujie Wang, Haiwei Wang, Mingxia Sun, Fandan Meng, Yan-Dong Tang, Yabin Tu, Qingke Kong, Tong-Qing An, Xue-Hui Cai

Source: Microbial Cell Factories, Vol 23, Iss 1, Pp 1-13 (2024)

Subject Terms: Porcine parvovirus, Virus-like particle, Minimal endotoxin activity, Escherichia coli, Lipid A, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2859

Access URL: https://doaj.org/article/76b5aab8e71349bea27177c50301c830

Immunogenicity and cross-protective efficacy induced by delayed attenuated Salmonella with regulated length of lipopolysaccharide in mice

Authors: Xiaoping Bian, Qing Liu, Yaolin Chen, Wenjin Zhang, Mengru Li, Xiaofen Zhang, Liu Yang, Yonghong Liao, Qingke Kong

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Regulated delayed attenuated Salmonella, outer membrane proteins, lipopolysaccharide, cross-protection, salmonella serotypes, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/68467598bcf247388381ed5d4654d1ac

Pioneering Role of Nanopore Single-Molecule Sensing in Environmental and Food Surveillance

Authors: Wenqiang Tian, Xu Wang, Yan Zhang, Ting Weng, Tlili Chaker, Xiaohan Chen, Qingke Kong, Deqiang Wang

Source: Biosensors, Vol 15, Iss 1, p 41 (2025)

Subject Terms: nanopores, single-molecule sensing, metal ions, additives, polymers, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6374/15/1/41; https://doaj.org/toc/2079-6374

Access URL: https://doaj.org/article/e00b12efd4a443538ee0e6b08e0e1892

Construction and Evaluation of an Efficient Live Attenuated Salmonella Choleraesuis Vaccine and Its Ability as a Vaccine Carrier to Deliver Heterologous Antigens

Authors: Xiaoping Bian, Jin Chen, Xin Chen, Chengying Liu, Jianjun Ding, Mengru Li, Xiaofen Zhang, Qing Liu, Qingke Kong

Source: Vaccines, Vol 12, Iss 3, p 249 (2024)

Subject Terms: live attenuated S. Choleraesuis, monophosphorylated lipid A, heterologous antigens, vaccine carrier, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/3/249; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/b61e56cd5e8f4e9da71fd0a88fc384e5

Effect of deletion of gene cluster involved in synthesis of Enterobacterial common antigen on virulence and immunogenicity of live attenuated Salmonella vaccine when delivering heterologous Streptococcus pneumoniae antigen PspA

Authors: Qing Liu, Xuegang Shen, Xiaoping Bian, Qingke Kong

Source: BMC Microbiology, Vol 20, Iss 1, Pp 1-12 (2020)

Subject Terms: ECA, Salmonella Typhimurium, Virulence, Vaccine vector, Th2 immunity, Microbiology, QR1-502

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12866-020-01837-0; https://doaj.org/toc/1471-2180

Access URL: https://doaj.org/article/e9e29363dcfb4b49a13a6b4bc8fe8b35

Optimized Attenuated Salmonella Typhimurium Suppressed Tumor Growth and Improved Survival in Mice

Authors: Kang Liang, Rui Zhang, Haiyan Luo, Jinlong Zhang, Zhenyuan Tian, Xiaofen Zhang, Yulin Zhang, Md Kaisar Ali, Qingke Kong

Source: Frontiers in Microbiology, Vol 12 (2021)

Subject Terms: Salmonella Typhimurium, cancer therapy, delivery, endostatin, TRAIL, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2021.774490/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/99dbdb9c4cdb4037bbfc7e63db37905a

Live attenuated Salmonella Typhimurium with monophosphoryl lipid A retains ability to induce T-cell and humoral immune responses against heterologous polysaccharide of Shigella flexneri 2a

Authors: Qing Liu, Huali Su, Xiaoping Bian, Shifeng Wang, Qingke Kong

Source: International Journal of Medical Microbiology, Vol 310, Iss 5, Pp 151427- (2020)

Subject Terms: Recombinant attenuated Salmonella vaccine, Shigella flexneri 2a, O-antigen polysaccharide, Antigen delivery, Microbiology, QR1-502, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1438422120300370; https://doaj.org/toc/1438-4221

Access URL: https://doaj.org/article/bcaa8082c9bb4ee7ac98d913615e4342

Attenuated Salmonella Typhimurium expressing Salmonella Paratyphoid A O-antigen induces protective immune responses against two Salmonella strains

Authors: Qing Liu, Pei Li, Hongyan Luo, Roy Curtiss, Qingke Kong

Source: Virulence, Vol 10, Iss 1, Pp 82-96 (2019)

Subject Terms: s. typhimurium, s. paratyphi a, paratyphoid fever, o-antigen, recombinant attenuated salmonella vaccine (rasv), Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/2150-5594; https://doaj.org/toc/2150-5608

Access URL: https://doaj.org/article/f8c8a6b8f04940aab91dcd65a50a13aa

Recombinant attenuated Salmonella Typhimurium with heterologous expression of the Salmonella Choleraesuis O-polysaccharide: high immunogenicity and protection

Authors: Xinxin Zhao, Qinlong Dai, Dekang Zhu, Mafeng Liu, Shun Chen, Kunfeng Sun, Qiao Yang, Ying Wu, Qingke Kong, Renyong Jia

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/4a9286ab7c4242bcbaefd653df4dc7a2

Identification of Fur in Pasteurella multocida and the Potential of Its Mutant as an Attenuated Live Vaccine

Authors: Qing Liu, Yunlong Hu, Pei Li, Qingke Kong

Source: Frontiers in Veterinary Science, Vol 6 (2019)

Subject Terms: Pasteurella multocida, fur, iron uptake, attenuated live vaccine, immune responses, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fvets.2019.00005/full; https://doaj.org/toc/2297-1769

Access URL: https://doaj.org/article/7ddc8b01389d4b0fa18cf5bfab9412a6

Construction of Escherichia coli Mutant with Decreased Endotoxic Activity by Modifying Lipid A Structure

Authors: Qiong Liu, Yanyan Li, Xinxin Zhao, Xue Yang, Qing Liu, Qingke Kong

Source: Marine Drugs, Vol 13, Iss 6, Pp 3388-3406 (2015)

Subject Terms: Escherichia coli BL21 (DE3), lipid A, pagL, lpxE, protein expression, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.mdpi.com/1660-3397/13/6/3388; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/05e95c683a2242ccb4f015ca412c16b7

O-Serotype Conversion in Salmonella Typhimurium Induces Protective Immune Responses against Invasive Non-Typhoidal Salmonella Infections

Authors: Pei Li, Qing Liu, Hongyan Luo, Kang Liang, Jie Yi, Ying Luo, Yunlong Hu, Yue Han, Qingke Kong

Source: Frontiers in Immunology, Vol 8 (2017)

Subject Terms: S. Typhimurium, S. Enteritidis, S. Choleraesuis, S. Newport, O-antigen, live attenuated Salmonella vaccine, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2017.01647/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/14578223ef00422c97b32e773ffba8fb

Comparative genome analysis of the high pathogenicity Salmonella Typhimurium strain UK-1.

Authors: Yingqin Luo, Qingke Kong, Jiseon Yang, Arindam Mitra, Greg Golden, Soo-Young Wanda, Kenneth L Roland, Roderick V Jensen, Peter B Ernst, Roy Curtiss

Source: PLoS ONE, Vol 7, Iss 7, p e40645 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3391293?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/04dbdcb07d664dbfbd85cb49f880412f

A biologically conjugated polysaccharide vaccine delivered by attenuated Salmonella Typhimurium provides protection against challenge of avian pathogenic Escherichia coli O1 infection.

Authors: Yue Han, Qing Liu, Jie Yi, Kang Liang, Yunan Wei, Qingke Kong

Source: Pathogens & Disease; Nov2017, Vol. 75 Issue 8, p1-11, 11p, 2 Diagrams, 2 Charts, 3 Graphs

Subject Terms: ESCHERICHIA coli mutation, ESCHERICHIA coli, ESCHERICHIA coli transmission, PATHOGENIC microorganisms, COMMUNICABLE diseases, FOOD pathogens, DISEASE risk factors

Identification of the crp gene in avian Pasteurella multocida and evaluation of the effects of crp deletion on its phenotype, virulence and immunogenicity.

Authors: Xinxin Zhao, Qing Liu, Kangpeng Xiao, Yunlong Hu, Xueyan Liu, Yanyan Li, Qingke Kong

Source: BMC Microbiology; 6/24/2016, Vol. 16, p1-13, 13p

Subject Terms: C-reactive protein, PASTEURELLA multocida, YERSINIA enterocolitica, SALMONELLA enterica, MICROBIAL virulence

A High-resolution Typing Assay for Uropathogenic Escherichia coli Based on Fimbrial Diversity.

Authors: Zhi Yao, Yi Wang, Xiao Li, Huiting Wei, Yi Ren, Quan Wang, Palusiak, Agata, Rozalski, Antoni, Wei Wang, Qingke Kong

Source: Frontiers in Microbiology; 4/29/2016, p1-10, 10p

Subject Terms: URINARY tract infections, ESCHERICHIA coli, PILI (Microbiology)

Identification of the Avian Pasteurella multocida phoP Gene and Evaluation of the Effects of phoP Deletion on Virulence and Immunogenicity.

Authors: Kangpeng Xiao, Qing Liu, Xueyan Liu, Yunlong Hu, Xinxin Zhao, Qingke Kong

Source: International Journal of Molecular Sciences; 2016, Vol. 17 Issue 1, p12, 15p, 1 Black and White Photograph, 6 Charts, 3 Graphs

Subject Terms: PASTEURELLA multocida, PATHOGENIC microorganisms, CHICKEN cholera, VACCINES, LIPOPOLYSACCHARIDES

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