Indoleamine 2, 3-dioxygenase 1 inhibition mediates the therapeutic effects in Parkinson's disease mice by modulating inflammation and neurogenesis in a gut microbiota dependent manner

Authors: Qiao, Chen-Meng ^{a, b, 1}, Ma, Xiao-Yu ^{a, b, 1}, Tan, Lu-Lu ^{a, b}, Xia, Yi-Meng ^{a, b}, Li, Ting ^{a, b}, Wu, Jian ^{a, b}, Cui, Chun ^{a, b}, Zhao, Wei-Jiang ^{a, b}, Shen, Yan-Qin ^{a, b, ⁎}

Source: In Experimental Neurology March 2025 385

Mechanism of S100A9-mediated astrocyte activation via TLR4/NF-κB in Parkinson’s disease

Authors: Qiao, Chen-Meng ^{a, b, 1}, Tan, Lu-Lu ^{a, b, 1}, Ma, Xiao-Yu ^{a, b}, Xia, Yi-Meng ^{a, b}, Li, Ting ^{a, b}, Li, Ming-An ^{a, b}, Wu, Jian ^{a, b}, Nie, Xin ^{a, b}, Cui, Chun ^{a, b}, Zhao, Wei-Jiang ^{a, b}, Shen, Yan-Qin ^{a, b, ⁎}

Source: In International Immunopharmacology 27 January 2025 146

Neuregulin 1 mitigated prolactin deficiency through enhancing TRPM8 signaling under the influence of melatonin in senescent pituitary lactotrophs

Authors: Zhang, Wei, Dao, Ji-ji, Li, Qian, Liu, Chong, Qiao, Chen-meng, Cui, Chun, Shen, Yan-qin, Zhao, Wei-jiang

Source: In International Journal of Biological Macromolecules August 2024 275 Part 1

Fecal Microbiota Transplantation from Aged Mice Render Recipient Mice Resistant to MPTP-Induced Nigrostriatal Degeneration Via a Neurogenesis-Dependent but Inflammation-Independent Manner

Authors: Qiao, Chen-Meng, Zhou, Yu, Quan, Wei, Ma, Xiao-Yu, Zhao, Li-Ping, Shi, Yun, Hong, Hui, Wu, Jian, Niu, Gu-Yu, Chen, Yu-Nuo, Zhu, Shan, Cui, Chun, Zhao, Wei-Jiang, Shen, Yan-Qin

Source: In Neurotherapeutics September 2023 20(5):1405-1426

DSS-induced acute colitis causes dysregulated tryptophan metabolism in brain: an involvement of gut microbiota

Authors: Zhao, Li-Ping, Wu, Jian, Quan, Wei, Zhou, Yu, Hong, Hui, Niu, Gu-Yu, Ting-Li, Huang, Shu-Bing, Qiao, Chen-Meng, Zhao, Wei-Jiang, Cui, Chun, Shen, Yan-Qin

Source: In The Journal of Nutritional Biochemistry May 2023 115

Akkermansia muciniphila Is Beneficial to a Mouse Model of Parkinson's Disease, via Alleviated Neuroinflammation and Promoted Neurogenesis, with Involvement of SCFAs.

Authors: Qiao, Chen-Meng¹ (AUTHOR), Huang, Wen-Yan¹ (AUTHOR), Zhou, Yu¹ (AUTHOR), Quan, Wei¹ (AUTHOR), Niu, Gu-Yu¹ (AUTHOR), Li, Ting¹ (AUTHOR), Zhang, Mei-Xuan¹ (AUTHOR), Wu, Jian¹ (AUTHOR), Zhao, Li-Ping¹ (AUTHOR), Zhao, Wei-Jiang¹ (AUTHOR), Cui, Chun¹ (AUTHOR), Shen, Yan-Qin¹ (AUTHOR) shenyanqin@jiangnan.edu.cn

Source: Brain Sciences (2076-3425). Mar2024, Vol. 14 Issue 3, p238. 19p.

Subject Terms: *PARKINSON'S disease, *NEUROINFLAMMATION, *NEUROGENESIS, *LABORATORY mice, *SHORT-chain fatty acids, *CALPROTECTIN

Targeted activation of ErbB4 receptor ameliorates neuronal deficits and neuroinflammation in a food-borne polystyrene microplastic exposed mouse model.

Authors: Liu, Chong, Zhao, Yan, Zhang, Wei, Dao, Ji-Ji, Li, Qian, Huang, Jia, Li, Zhen-Feng, Ma, Yu-Ke, Qiao, Chen-Meng, Cui, Chun, Chen, Shuang-Xi, Yu, Li, Shen, Yan-Qin, Zhao, Wei-Jiang

Source: Journal of Neuroinflammation; 3/15/2025, Vol. 22 Issue 1, p1-20, 20p

Subject Terms: EPIDERMAL growth factor receptors, MEDICAL sciences, NERVOUS system regeneration, SMALL molecules, NERVOUS system

Targeted ErbB4 receptor activation prevents D-galactose-induced neuronal senescence via inhibiting ferroptosis pathway.

Authors: Dao, Ji-Ji, Zhang, Wei, Liu, Chong, Li, Qian, Qiao, Chen-Meng, Cui, Chun, Shen, Yan-Qin, Chen, Shuang-Xi, Zhao, Wei-Jiang

Source: Frontiers in Pharmacology; 2025, p1-17, 17p

Subject Terms: VIRTUAL high-throughput screening (Drug development), HIPPOCAMPUS diseases, BEHAVIORAL assessment, SMALL molecules, NEURODEGENERATION

Adequate expression of neuropeptide Y is essential for the recovery of zebrafish motor function following spinal cord injury

Authors: Cui, Chun, Wang, Lin-Fang, Huang, Shu-Bing, Zhao, Peng, Chen, Yong-Quan, Wu, Yi-Bo, Qiao, Chen-Meng, Zhao, Wei-Jiang, Shen, Yan-Qin

Source: In Experimental Neurology November 2021 345

Dynamic changes of activated AHR in microglia and astrocytes in the substantia nigra-striatum system in an MPTP-induced Parkinson's disease mouse model

Authors: Zhou, Yu, Zhao, Wei-Jiang, Quan, Wei, Qiao, Chen-Meng, Cui, Chun, Hong, Hui, Shi, Yun, Niu, Gu-Yu, Zhao, Li-Ping, Shen, Yan-Qin

Source: Brain research bulletin. 176:174-183

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139939260.0x000001&indx=1&recIds=ETOCvdc_100139939260.0x000001

Trimethylamine N-Oxide Exacerbates Neuroinflammation and Motor Dysfunction in an Acute MPTP Mice Model of Parkinson's Disease.

Authors: Quan, Wei¹ (AUTHOR), Qiao, Chen-Meng¹ (AUTHOR), Niu, Gu-Yu¹ (AUTHOR) 6202805016@stu.jiangnan.edu.cn, Wu, Jian¹ (AUTHOR), Zhao, Li-Ping¹ (AUTHOR), Cui, Chun¹ (AUTHOR), Zhao, Wei-Jiang¹ (AUTHOR), Shen, Yan-Qin¹ (AUTHOR) shenyanqin@jiangnan.edu.cn

Source: Brain Sciences (2076-3425). May2023, Vol. 13 Issue 5, p790. 14p.

Subject Terms: *PARKINSON'S disease, *ANIMAL disease models, *NEUROINFLAMMATION, *TRIMETHYLAMINE, *LABORATORY mice

Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway

Authors: Qiao, Chen-Meng, Sun, Meng-Fei, Jia, Xue-Bing, Shi, Yun, Zhang, Bo-Ping, Zhou, Zhi-Lan, Zhao, Li-Ping, Cui, Chun, Shen, Yan-Qin

Source: In Experimental Cell Research 1 February 2020 387(1)

Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites

Authors: Zhou, Zhi-Lan, Jia, Xue-Bing, Sun, Meng-Fei, Zhu, Ying-Li, Qiao, Chen-Meng, Zhang, Bo-Ping, Zhao, Li-Ping, Yang, Qin, Cui, Chun, Chen, Xue, Shen, Yan-Qin

Source: In Neurotherapeutics 15 July 2019 16(3):741-760

Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model

Authors: Qiao, Chen-Meng, Sun, Meng-Fei, Jia, Xue-Bing, Li, Yang, Zhang, Bo-Ping, Zhao, Li-Ping, Shi, Yun, Zhou, Zhi-Lan, Zhu, Ying-Li, Cui, Chun, Shen, Yan-Qin

Source: NEUROCHEMICAL RESEARCH. 45(9):2128-2142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171684971.0x000001&indx=1&recIds=ETOCvdc_100171684971.0x000001

Neuroprotective effects of Astilbin on MPTP-induced Parkinson's disease mice: Glial reaction, α-synuclein expression and oxidative stress

Authors: Zhu, Ying-Li, Sun, Meng-Fei, Jia, Xue-Bing, Cheng, Kun, Xu, Yi-Da, Zhou, Zhi-Lan, Zhang, Pei-Hao, Qiao, Chen-Meng, Cui, Chun, Chen, Xue, Yang, Xu-Sheng, Shen, Yan-Qin

Source: In International Immunopharmacology January 2019 66:19-27

Anti—inflammation Effect and The Mechanism of Suitable Concentration of Short—chain Fatty Acids Mixture on Microglia

Authors: Jia, Xue-Bing, Zhou, Zhi-Lan, Zhang, Bo-Ping, Zhao, Li-Ping, Qiao, Chen-Meng, Sun, Meng-Fei, Sun, Xiu-Lan, Chen, Yong-Quan, Cui, Chun, Shen, Yan-Qin

Source: Shengwu huaxue yu shengwu wuli jinzhan. 46(5):504-512

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN621526910&indx=1&recIds=ETOCRN621526910

A Pilot Study on a Possible Mechanism behind Olfactory Dysfunction in Parkinson's Disease: The Association of TAAR1 Downregulation with Neuronal Loss and Inflammation along Olfactory Pathway.

Authors: Zhang, Mei-Xuan, Hong, Hui, Shi, Yun, Huang, Wen-Yan, Xia, Yi-Meng, Tan, Lu-Lu, Zhao, Wei-Jiang, Qiao, Chen-Meng, Wu, Jian, Zhao, Li-Ping, Huang, Shu-Bing, Jia, Xue-Bing, Shen, Yan-Qin, Cui, Chun

Source: Brain Sciences (2076-3425); Apr2024, Vol. 14 Issue 4, p300, 18p

Subject Terms: PARKINSON'S disease, SMELL disorders, ENCEPHALITIS, DOWNREGULATION, INFLAMMATION

Orally Induced High Serum Level of Trimethylamine N-oxide Worsened Glial Reaction and Neuroinflammation on MPTP-Induced Acute Parkinson's Disease Model Mice.

Authors: Qiao, Chen-Meng, Quan, Wei, Zhou, Yu, Niu, Gu-Yu, Hong, Hui, Wu, Jian, Zhao, Li-Ping, Li, Ting, Cui, Chun, Zhao, Wei-Jiang, Shen, Yan-Qin

Source: Molecular Neurobiology; Sep2023, Vol. 60 Issue 9, p5137-5154, 18p

Vancomycin Pretreatment on MPTP-Induced Parkinson's Disease Mice Exerts Neuroprotection by Suppressing Inflammation Both in Brain and Gut.

Authors: Cui, Chun, Hong, Hui, Shi, Yun, Zhou, Yu, Qiao, Chen-Meng, Zhao, Wei-Jiang, Zhao, Li-Ping, Wu, Jian, Quan, Wei, Niu, Gu-Yu, Wu, Yi-Bo, Li, Chao-Sheng, Cheng, Li, Hong, Yan, Shen, Yan-Qin

Source: Journal of NeuroImmune Pharmacology; Jun2023, Vol. 18 Issue 1/2, p72-89, 18p

Protective effects of prucalopride in MPTP-induced Parkinson’s disease mice: Neurochemistry, motor function and gut barrier

Authors: Shi, Yun, Qiao, Chen-Meng, Zhou, Yu, Wu, Ji, Cui, Chun, Hong, Hui, Jia, Xue-Bing, Huang, Shu-Bing, Yao, Li, Zhao, Wei-Jiang, Shen, Yan-Qin

Source: In Biochemical and Biophysical Research Communications 4 June 2021 556:16-22