Mitochondrial chaperon TNF-receptor- associated protein 1 as a novel apoptotic regulator conferring susceptibility to Pneumocystis jirovecii pneumonia

Authors: Aseervatham Anusha Amali, Kathirvel Paramasivam, Chiung Hui Huang, Abhinav Joshi, Jayshree L. Hirpara, Sharada Ravikumar, Qi Hui Sam, Rachel Ying Min Tan, Zhaohong Tan, Dilip Kumar, Leonard M. Neckers, Shazib Pervaiz, Roger Foo, Candice Y Y Chan, Jin Zhu, Cheryl Lee, Louis Yi Ann Chai

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: opportunistic infection, mitochondria, oxidative phosphorylation, glycolysis, caspase, apoptosis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423086/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e1cb52a4b17842cf89640d2446bca83c

Engineering of a probiotic yeast for the production and secretion of medium-chain fatty acids antagonistic to an opportunistic pathogen Candida albicans

Authors: Hua Ling, Ruirui Liu, Qi Hui Sam, Haosheng Shen, Louis Yi Ann Chai, Matthew Wook Chang

Source: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Subject Terms: probiotic yeast, medium-chain fatty acids, Candida albicans, virulence, immunomodulation, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1090501/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/b21f96c73e044ab09c72a432f903c1b8

Tocilizumab Induces IL-10-Mediated Immune Tolerance in Invasive Candidiasis

Authors: Zhaohong Tan, Michelle Meng Huang Mok, Win Mar Soe, Thomas Paulraj Thamboo, Jessamine Geraldine Goh, Qi Hui Sam, Motomi Osato, Sharada Ravikumar, Louis Yi Ann Chai

Source: Journal of Fungi, Vol 7, Iss 8, p 656 (2021)

Subject Terms: Candida albicans, interleukin 6 blockade, inflammation, immunomodulation, monoclonal antibody, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2309-608X/7/8/656; https://doaj.org/toc/2309-608X

Access URL: https://doaj.org/article/5049391d15ec4ecd9a941c0a257a31bf

Using Expanded Natural Killer Cells as Therapy for Invasive Aspergillosis

Authors: Win Mar Soe, Joan Hui Juan Lim, David L. Williams, Jessamine Geraldine Goh, Zhaohong Tan, Qi Hui Sam, Sanjay H. Chotirmall, Nur A’tikah Binte Mohamed Ali, Soo Chin Lee, Ju Ee Seet, Sharada Ravikumar, Louis Yi Ann Chai

Source: Journal of Fungi, Vol 6, Iss 4, p 231 (2020)

Subject Terms: Aspergillus, antifungal immunity, fungal infection, immune evasion, immune recognition, expanded natural killer cells, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2309-608X/6/4/231; https://doaj.org/toc/2309-608X

Access URL: https://doaj.org/article/7ddb520318c04175b035c422d949d17f

Immunomodulation as Therapy for Fungal Infection: Are We Closer?

Authors: Qi Hui Sam, Wen Shan Yew, Chaminda J. Seneviratne, Matthew Wook Chang, Louis Yi Ann Chai

Source: Frontiers in Microbiology, Vol 9 (2018)

Subject Terms: immunotherapy, mycosis, invasive fungal disease, aspergillosis, candidiasis, anti-fungal, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmicb.2018.01612/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/b7fc703839b743568dbf2fea88445735

Mitochondrial chaperon TNF-receptor- associated protein 1 as a novel apoptotic regulator conferring susceptibility to Pneumocystis jirovecii pneumonia.

Authors: Amali, Aseervatham Anusha, Paramasivam, Kathirvel, Chiung Hui Huang, Joshi, Abhinav, Hirpara, Jayshree L., Ravikumar, Sharada, Qi Hui Sam, Min Tan, Rachel Ying, Zhaohong Tan, Kumar, Dilip, Neckers, Leonard M., Pervaiz, Shazib, Foo, Roger, Y Chan, Candice Y, Jin Zhu, Lee, Cheryl, Ann Chai, Louis Yi

Source: Frontiers in Immunology; 2024, p1-9, 9p

Subject Terms: PNEUMOCYSTIS pneumonia, MONONUCLEAR leukocytes, OPPORTUNISTIC infections, GENETIC variation, OXIDATIVE phosphorylation, PNEUMOCYSTIS jiroveci

The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host.

Authors: Qi Hui Sam¹ qi_hui_sam@nuhs.edu.sg, Matthew Wook Chang^2,3 bchcmw@nus.edu.sg, Louis Yi Ann Chai^1,4 chailouis@hotmail.com

Source: International Journal of Molecular Sciences. Feb2017, Vol. 18 Issue 2, p330. 11p.

Subject Terms: *MYCOBIOME, *FUNGI, *GUT microbiome, *MICROORGANISMS, *BIOMES, *SYMBIOSIS

Using Expanded Natural Killer Cells as Therapy for Invasive Aspergillosis.

Authors: Soe, Win Mar, Hui Juan Lim, Joan, Williams, David L., Goh, Jessamine Geraldine, Zhaohong Tan, Qi Hui Sam, Chotirmall, Sanjay H., Mohamed Ali, Nur A'tikah Binte, Soo Chin Lee, Ju Ee Seet, Ravikumar, Sharada, Yi Ann Chai, Louis

Source: Journal of Fungi; Dec2020, Vol. 6 Issue 4, p1-12, 12p

Subject Terms: KILLER cells, ASPERGILLOSIS, IMMUNE system, ANTIFUNGAL agents, LIGANDS (Biochemistry)