Characterizing the SARS-CoV-2 antibody response and associations with patient factors: Serological profiling of participants enrolled in the GENCOV study

Authors: Morgan, Gregory ^{a, b, c}, Fung, Chun Yiu Jordan ^{a, b}, Gingras, Anne-Claude ^{a, d}, Colwill, Karen ^a, Briollais, Laurent ^a, Frangione, Erika ^{a, b}, Wolday, Dawit ^e, Qi, Freda ^a, Pasculescu, Adrian ^a, Delgado-Brand, Melanie ^a, Mailhot, Genevieve ^f, Tursun, Tulunay ^a, Arnoldo, Saranya ^{c, g}, Bearss, Erin ^{h, i}, Binnie, Alexandra ^j, Borgundvaag, Bjug ^k, Casalino, Selina ^{a, b}, Chowdhary, Sunakshi ^l, Dagher, Marc ^{i, m}, Devine, Luke ^{n, o}, Elliott, Lloyd T. ^p, Friedman, Steven M. ^{i, q}, Khan, Zeeshan ^r, Lapadula, Elisa ^{a, b}, MacDonald, Georgia ^{a, b}, Mazzulli, Tony ^{c, s}, McLeod, Shelley L ^{i, k}, Mighton, Chloe ^{t, u}, Nirmalanathan, Konika ^q, Richardson, David ^g, Stern, Seth ^r, Taher, Ahmed ^{r, v}, Young, Juliet ^{a, b}, Lerner-Ellis, Jordan ^{a, b, c}, Taher, Jennifer ^{b, c, ⁎}

Source: In Clinical Biochemistry January 2025 135

Immunogenicity of COVID-19 vaccines and their effect on HIV reservoir in older people with HIV

Authors: Matveev, Vitaliy A., Mihelic, Erik Z., Benko, Erika, Budylowski, Patrick, Grocott, Sebastian, Lee, Terry, Korosec, Chapin S., Colwill, Karen, Stephenson, Henry, Law, Ryan, Ward, Lesley A., Sheikh-Mohamed, Salma, Mailhot, Geneviève, Delgado-Brand, Melanie, Pasculescu, Adrian, Wang, Jenny H., Qi, Freda, Tursun, Tulunay, Kardava, Lela, Chau, Serena, Samaan, Philip, Imran, Annam, Copertino, Dennis C., Jr., Chao, Gary, Choi, Yoojin, Reinhard, Robert J., Kaul, Rupert, Heffernan, Jane M., Jones, R. Brad, Chun, Tae-Wook, Moir, Susan, Singer, Joel, Gommerman, Jennifer, Gingras, Anne-Claude, Kovacs, Colin, Ostrowski, Mario

Source: In iScience 20 October 2023 26(10)

A bivalent COVID-19 mRNA vaccine elicited broad immune responses and protection against Omicron subvariants infection.

Authors: Liu, Jun, Wang, Li, Kurtesi, Alexandra, Budylowski, Patrick, Potts, Kyle G., Menon, Haritha, Tan, Yilin, Samaan, Philip, Liu, Xinan, Wang, Yisen, Hu, Queenie, Samson, Reuben, Qi, Freda, Evseev, Danyel, John, Cini, Ellestad, Kristofor K., Fan, Yue, Budiman, Frans, Tohan, Ellaine Riczly, Udayakumar, Suji

Source: NPJ Vaccines; 1/10/2025, Vol. 10 Issue 1, p1-15, 15p

Subject Terms: SARS-CoV-2 Omicron variant, BOOSTER vaccines, VACCINE approval, LUNG infections, COVID-19 vaccines, T cells

Hybrid immunity from severe acute respiratory syndrome coronavirus 2 infection and vaccination in Canadian adults: A cohort study.

Authors: Brown, Patrick E., Sze Hang Fu, Newcombe, Leslie, Xuyang Tang, Nagelkerke, Nico, Birnboim, H. Chaim, Bansal, Aiyush, Colwill, Karen, Mailhot, GeneviÃ?ve, Delgado-Brand, Melanie, Tursun, Tulunay, Qi, Freda, Gingras, Anne-Claude, Slutsky, Arthur S., Pasic, Maria D., Companion, Jeffrey, Bogoch, Isaac I., Morawski, Ed, Lam, Teresa, Reid, Angus

Source: eLife; 7/26/2024, p1-22, 22p

Bivalent COVID-19 mRNA vaccine against omicron subvariants in immunocompromised patients

Authors: Solera, Javier T, Ierullo, Matthew, Arbol, Berta G, Mavandadnejad, Faranak, Kurtesi, Alexandra, Qi, Freda, Hu, Queenie, Gingras, Anne-Claude, Ferreira, Victor H, Humar, Atul, Kumar, Deepali

Source: Lancet infectious diseases. 23(8):e266-e267

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194868379.0x000001&indx=1&recIds=ETOCvdc_100194868379.0x000001

Declining Levels of Neutralizing Antibodies to SARS-CoV-2 Omicron Variants Are Enhanced by Hybrid Immunity and Original/Omicron Bivalent Vaccination.

Authors: Walmsley, Sharon, Nabipoor, Majid, Qi, Freda, Lovblom, Leif Erik, Ravindran, Rizani, Colwill, Karen, Dayam, Roya Monica, Tursun, Tulunay R., Silva, Amanda, Gingras, Anne-Claude

Source: Vaccines; Jun2024, Vol. 12 Issue 6, p564, 21p

Subject Terms: SARS-CoV-2 Omicron variant, SARS-CoV-2, IMMUNOGLOBULINS, BREAKTHROUGH infections, ANTIBODY titer

Geographic Terms: WUHAN (China)

155 SARS-CoV-2 Breakthrough Infection Increases the Adaptive Immune Responses of Vaccinated Immunosuppressed Children

Authors: Nantel, Sabryna, Sassine, Samuel, Rabezanahary, Henintsoa, Qi, Freda, Ward, Lesley, Wang, Louise, Bourdin, Benoîte, Colwill, Karen, Chao, Gary, Torre, Margot Barbosa Da, Zinzser, Kate, Gommerman, Jennifer, Gingras, Anne-Claude, Baz, Mariana, Quach, Caroline, Decaluwe, Helene

Source: In Clinical Immunology May 2024 262 Supplement

Humoral Response Following 3 Doses of mRNA COVID-19 Vaccines in Patients With Non-Dialysis-Dependent CKD: An Observational Study.

Authors: Enilama, Omosomi, Yau, Kevin, Er, Lee, Atiquzzaman, Mohammad, Oliver, Matthew J., Romney, Marc G., Leis, Jerome A., Abe, Kento T., Qi, Freda, Colwill, Karen, Gingras, Anne-Claude, Hladunewich, Michelle A., Levin, Adeera

Source: Canadian Journal of Kidney Health & Disease; 1/29/2024, p1-11, 11p

Omicron variant neutralizing antibodies following BNT162b2 BA.4/5 versus mRNA-1273 BA.1 bivalent vaccination in patients with end-stage kidney disease.

Authors: Yau, Kevin, Kurtesi, Alexandra, Qi, Freda, Delgado-Brand, Melanie, Tursun, Tulunay R., Hu, Queenie, Dhruve, Miten, Kandel, Christopher, Enilama, Omosomi, Levin, Adeera, Jiang, Yidi, Hardy, W. Rod, Yuen, Darren A., Perl, Jeffrey, Chan, Christopher T., Leis, Jerome A., Oliver, Matthew J., Colwill, Karen, Gingras, Anne-Claude, Hladunewich, Michelle A.

Source: Nature Communications; 9/27/2023, Vol. 14 Issue 1, p1-8, 8p

Subject Terms: CHRONIC kidney failure, SARS-CoV-2 Omicron variant, IMMUNOGLOBULINS, COVID-19 vaccines, VACCINATION, KIDNEY transplantation

RHAMM regulates MMTV-PyMT-induced lung metastasis by connecting STING-dependent DNA damage sensing to interferon/STAT1 pro-apoptosis signaling.

Authors: Tolg, Cornelia, Milojevic, Maja, Qi, Freda W., Pavanel, Hailie A., Locke, M. Elizabeth O., Ma, Jenny, Price, Mathew, Nelson, Andrew C., McCarthy, James B., Hill, Kathleen A., Turley, Eva A.

Source: Breast Cancer Research; 6/22/2023, Vol. 25 Issue 1, p1-17, 17p

Subject Terms: GENE expression, DNA damage, SOMATIC mutation, CELL death, METASTATIC breast cancer, LUNGS, GENOME editing

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mRNA vaccine-induced SARS-CoV-2 spike-specific IFN-γ and IL-2 T-cell responses are predictive of serological neutralization and are transiently enhanced by pre-existing cross-reactive immunity.

Authors: Samaan, Philip¹, Korosec, Chapin S.^2,3, Budylowski, Patrick^4,5, Chau, Serena L. L.⁵, Pasculescu, Adrian⁶, Qi, Freda⁶, DelgadoBrand, Melanie⁶, Tursun, Tulunay R.⁶, Mailhot, Geneviève⁶, Dayam, Roya Monica⁶, Arnold, Corey R.⁷, Langlois, Marc-André⁷, Mendoza, Justin⁵, Morningstar, Thomas⁵, Law, Ryan⁵, Mihelic, Erik⁵, Sheikh-Mohamed, Salma⁸, Cao, Eric Yixiao⁸, Paul, Nimitha⁹, Patel, Anjali⁹

Source: Journal of Virology. Mar2025, Vol. 99 Issue 3, p1-28. 28p.

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