Targeted molecular therapies in thyroid carcinoma

Authors: Romagnoli, Serena, Moretti, Sonia, Voce, Pasquale, Puxeddu, Efisio

Source: Arquivos Brasileiros de Endocrinologia & Metabologia. December 2009 53(9)

Subject Terms: Thyroid carcinoma, radioiodine therapy, external beam radiation therapy, cytotoxic chemotherapy, targeted therapies, tyrosine kinase inhibitors

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302009000900002

Clinical prognosis in BRAF-mutated PTC

Authors: Puxeddu, Efisio, Moretti, Sonia

Source: Arquivos Brasileiros de Endocrinologia & Metabologia. July 2007 51(5)

Subject Terms: BRAF mutation, Papillary thyroid carcinoma, Prognostic stratification, Prognostic marker, Iodine metabolism, 131I ablative treatment

File Description: text/html

Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302007000500011

Classification of Thyroid Diseases Using Machine Learning and Bayesian Graph Algorithms

Authors: Mollica, Giuseppe, Francesconi, Daniela, Costante, Gabriele, Moretti, Sonia, Giannini, Riccardo, Puxeddu, Efisio, Valigi, Paolo

Source: In IFAC PapersOnLine 2022 55(40):67-72

BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer

Authors: Tao, Yubing, Wang, Fei, Shen, Xiaopei, Zhu, Guangwu, Liu, Rengyun, Viola, David, Elisei, Rossella, Puxeddu, Efisio, Fugazzola, Laura, Colombo, Carla, Jarzab, Barbara, Czarniecka, Agnieszka, Lam, Alfred K, Mian, Caterina, Vianello, Federica, Yip, Linwah, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, O'Neill, Christine J, Sywak, Mark S, Clifton-Bligh, Roderick, Bendlova, Bela, Sýkorová, Vlasta, Zhao, Shihua, Wang, Yangang, Xing, Mingzhao

Source: Journal of clinical endocrinology & metabolism. 106(11):3228-3238

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136537399.0x000001&indx=1&recIds=ETOCvdc_100136537399.0x000001

The Stone Guest: How Does pH Affect Binding Properties of PD‐1/PD‐L1 Inhibitors?

Authors: Riccio, Alessandra, Coletti, Alice, Dolciami, Daniela, Mammoli, Andrea, Cerra, Bruno, Moretti, Sonia, Gioiello, Antimo, Ferlin, Simone, Puxeddu, Efisio, Macchiarulo, Antonio

Source: ChemMedChem. 16(3):568-577

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114351259.0x000001&indx=1&recIds=ETOCvdc_100114351259.0x000001

Minimal Extrathyroidal Extension in Predicting 1-Year Outcomes: A Longitudinal Multicenter Study of Low-to-Intermediate-Risk Papillary Thyroid Carcinoma (ITCO#4)

Authors: Forleo, Raffaella, Grani, Giorgio, Alfò, Marco, Zilioli, Valentina, Giubbini, Raffaele, Zatelli, Maria Chiara, Gagliardi, Irene, Piovesan, Alessandro, Ragni, Alberto, Morelli, Silvia, Puxeddu, Efisio, Pagano, Loredana, Deandrea, Maurilio, Ceresini, Graziano, Torlontano, Massimo, Puligheddu, Barbara, Antonelli, Alessandro, Centanni, Marco, Fugazzola, Laura, Spiazzi, Giovanna, Monti, Salvatore, Rossetto, Ruth, Monzani, Fabio, Tallini, Giovanni, Crescenzi, Anna, Sparano, Clotilde, Bruno, Rocco, Repaci, Andrea, Tumino, Dario, Pezzullo, Luciano, Lombardi, Celestino Pio, Ferraro Petrillo, Umberto, Filetti, Sebastiano, Durante, Cosimo, Castagna, Maria Grazia

Source: Thyroid. 31(12):1814-1821

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136889477.0x000001&indx=1&recIds=ETOCvdc_100136889477.0x000001

BRAF V600E status may facilitate decision-making on active surveillance of low-risk papillary thyroid microcarcinoma

Authors: Kim, Kyeong J., Kim, Sin G., Tan, Jie, Shen, Xiaopei, Viola, David, Elisei, Rossella, Puxeddu, Efisio, Fugazzola, Laura, Colombo, Carla, Jarzab, Barbara, Czarniecka, Agnieszka, Lam, Alfred K., Mian, Caterina, Vianello, Federica, Yip, Linwah, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, O'Neill, Christine J., Sywak, Mark S., Clifton-Bligh, Roderick, Bendlova, Bela, Sýkorová, Vlasta, Xing, Mingzhao

Source: In European Journal of Cancer January 2020 124:161-169

Silencing of hTERT blocks growth and migration of anaplastic thyroid cancer cells

Authors: Maggisano, Valentina, Celano, Marilena, Lombardo, Giovanni Enrico, Lepore, Saverio Massimo, Sponziello, Marialuisa, Rosignolo, Francesca, Verrienti, Antonella, Baldan, Federica, Puxeddu, Efisio, Durante, Cosimo, Filetti, Sebastiano, Damante, Giuseppe, Russo, Diego, Bulotta, Stefania

Source: In Molecular and Cellular Endocrinology 15 June 2017 448:34-40

Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1

Authors: Moretti, Sonia, Menicali, Elisa, Nucci, Nicole, Voce, Pasquale, Colella, Renato, Melillo, Rosa Marina ^**, Liotti, Federica, Morelli, Silvia, Fallarino, Francesca, Macchiarulo, Antonio, Santoro, Massimo, Avenia, Nicola, Puxeddu, Efisio

Source: In Journal of Biological Chemistry 3 February 2017 292(5):1785-1797

Long glucocorticoid-induced leucine zipper regulates human thyroid cancer cell proliferation

Authors: Ayroldi, Emira, Petrillo, Maria, Marchetti, Maria, Cannarile, Lorenza, Ronchetti, Simona, Ricci, Erika, Cari, Luigi, Avenia, Nicola, Moretti, Sonia, Puxeddu, Efisio, Riccardi, Carlo

Source: Cell death and disease. 9(3):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114648539.0x000001&indx=1&recIds=ETOCvdc_100114648539.0x000001

Targeting the thyroid gland with thyroid-stimulating hormone (TSH)-nanoliposomes

Authors: Paolino, Donatella, Cosco, Donato, Gaspari, Marco, Celano, Marilena, Wolfram, Joy, Voce, Pasquale, Puxeddu, Efisio, Filetti, Sebastiano, Celia, Christian, Ferrari, Mauro, Russo, Diego, Fresta, Massimo

Source: In Biomaterials August 2014 35(25):7101-7109

A Prospective Multicenter Study Examining the Relationship Between Thyroid Cancer Treatment Outcomes and the Presence of Autoimmune Thyroiditis.

Authors: De Leo, Simone, D'Elia, Silvia, Grani, Giorgio, Dondi, Francesco, Bertagna, Francesco, Puxeddu, Efisio, Morelli, Silvia, Piovesan, Alessandro, Nervo, Alice, Zatelli, Maria Chiara, Gagliardi, Irene, Samà, Maria Teresa, Aimaretti, Gianluca, Crocetti, Umberto, Massa, Michela, Deandrea, Maurilio, Retta, Francesca, Pagano, Loredana, Rossi, Mattia, Solaroli, Erica

Source: Thyroid; Nov2023, Vol. 33 Issue 11, p1318-1326, 9p

Subject Terms: AUTOIMMUNE thyroiditis, THYROIDITIS, PROPENSITY score matching, TREATMENT effectiveness, CANCER treatment, THYROID cancer, AUTOIMMUNITY

Fifteen Years of Iodine Prophylaxis in Italy: Results of a Nationwide Surveillance (Period 2015-2019)

Authors: De Angelis, Simona, Medda, Emanuela, Rotondi, Daniela, Masocco, Maria, Minardi, Valentina, Contoli, Benedetta, Possenti, Valentina, Sorbo, Angela, D’Amato, Marilena, Turco, Anna Chiara, Pastorelli, Alberto Augusto, Stacchini, Paolo, Cas, Roberto Da, Bagnasco, Marcello, Bonofiglio, Daniela, Gasperi, Maurizio, Meringolo, Domenico, Mian, Caterina, Moleti, Mariacarla, Vermiglio, Francesco, Puxeddu, Efisio, Taccaliti, Augusto, Tonacchera, Massimo, Ulisse, Salvatore, Dimida, Antonio, Rago, Teresa, Nazzari, Elena, Schiavo, Mara, Bossert, Irene, Sturniolo, Giacomo, Corbetta, Carlo, Cereda, Cristina, Cappelletti, Laura, Camilot, Marta, Teofoli, Francesca, Ciatti, Renzo, Tarsi, Elisabetta, Perrotti, Nicola, Marasco, Onorina, Scozzafava, Giovanna, Righetti, Francesca, Andò, Sebastiano, Catalano, Stefania, Cristofaro, Mariarosaria, Sorrenti, Giovanni, Censi, Simona, Morelli, Silvia, Baldini, Enke, Plutino, Giuseppe, Copparoni, Roberto, Alonzo, Elena, Giacomozzi, Claudia, Silano, Marco, Olivieri, Antonella

Source: The Journal of Clinical Endocrinology & Metabolism; February 2024, Vol. 109 Issue: 2 pe495-e507, 13p

A Data-Driven Approach to Refine Predictions of Differentiated Thyroid Cancer Outcomes: A Prospective Multicenter Study.

Authors: Grani, Giorgio, Gentili, Michele, Siciliano, Federico, Albano, Domenico, Zilioli, Valentina, Morelli, Silvia, Puxeddu, Efisio, Zatelli, Maria Chiara, Gagliardi, Irene, Piovesan, Alessandro, Nervo, Alice, Crocetti, Umberto, Massa, Michela, Samà, Maria Teresa, Mele, Chiara, Deandrea, Maurilio, Fugazzola, Laura, Puligheddu, Barbara, Antonelli, Alessandro, Rossetto, Ruth

Source: Journal of Clinical Endocrinology & Metabolism; Aug2023, Vol. 108 Issue 8, p1921-1928, 8p

Subject Terms: THYROID cancer, CLINICAL trials

B-Raf V600E and thrombospondin-1 promote thyroid cancer progression

Authors: Nucera, Carmelo, Porrello, Alessandro, Antonello, Zeus Andrea, Mekel, Michal, Nehs, Matthew A., Giordano, Thomas J., Gerald, Damien, Benjamin, Laura E., Priolo, Carmen, Puxeddu, Efisio, Finn, Stephen, Jarzab, Barbara, Hodin, Richard A., Pontecorvi, Alfredo, Nose, Vânia, Lawler, Jack, Parangi, Sareh, Donahoe, Patricia K.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2010 Jun 01. 107(23), 10649-10654.

Access URL: https://www.jstor.org/stable/25681837

Gemcitabine-loaded biocompatible nanocapsules for the effective treatment of human cancer

Authors: Paolino, Donatella, Cosco, Donato, Celano, Marilena, Moretti, Sonia, Puxeddu, Efisio, Russo, Diego, Fresta, Massimo

Source: Nanomedicine. 8(2):193-201

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140760916.0x000001&indx=1&recIds=ETOCvdc_100140760916.0x000001

Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR ®: Biodistribution, pharmacokinetic features and in vivo antitumor activity

Authors: Paolino, Donatella, Cosco, Donato, Racanicchi, Leda, Trapasso, Elena, Celia, Christian, Iannone, Michelangelo, Puxeddu, Efisio, Costante, Giuseppe, Filetti, Sebastiano, Russo, Diego, Fresta, Massimo

Source: In Journal of Controlled Release 2010 144(2):144-150

Insights into the molecular function of the inactivating mutations of B-Raf involving the DFG motif

Authors: Moretti, Sonia, De Falco, Valentina, Tamburrino, Anna, Barbi, Flavia, Tavano, Maria, Avenia, Nicola, Santeusanio, Fausto, Santoro, Massimo, Macchiarulo, Antonio, Puxeddu, Efisio

Source: In BBA - Molecular Cell Research 2009 1793(11):1634-1645

Turning a Tumor Microenvironment Pitfall into Opportunity: Discovery of Benzamidoxime as PD-L1 Ligand with pH-Dependent Potency.

Authors: Bianconi, Elisa, Riccio, Alessandra, Ruta, Luana, Bigiotti, Carlo, Carotti, Andrea, Moretti, Sonia, Cerra, Bruno, Gioiello, Antimo, Ferlin, Simone, Puxeddu, Efisio, Macchiarulo, Antonio

Source: International Journal of Molecular Sciences; Mar2023, Vol. 24 Issue 6, p5535, 16p

Subject Terms: PROGRAMMED death-ligand 1, TUMOR microenvironment, SMALL molecules, STRUCTURE-activity relationships, PROGRAMMED cell death 1 receptors

Clinical implications of BRAF mutation in thyroid carcinoma

Authors: Puxeddu, Efisio, Durante, Cosimo, Avenia, Nicola, Filetti, Sebastiano, Russo, Diego

Source: In Trends in Endocrinology & Metabolism 2008 19(4):138-145