Dandruff lesional scalp skin exhibits epidermal T cell infiltration and a weakened hair follicle immune privilege.

Authors: Limbu, Susan L.¹ (AUTHOR), Purba, Talveen S.¹ (AUTHOR), Harries, Matthew^1,2 (AUTHOR), Kundu, Rhia³ (AUTHOR), Bhogal, Ranjit K.³ (AUTHOR), Paus, Ralf^1,4,5,6 (AUTHOR) rxp803@med.miami.edu

Source: International Journal of Cosmetic Science. Oct2024, Vol. 46 Issue 5, p717-733. 17p.

Subject Terms: *LANGERHANS cells, *SKIN physiology, *MAST cells, *HAIR follicles, *HAIR growth

Interleukin-15 is a hair follicle immune privilege guardian

Authors: Suzuki, Takahiro, Chéret, Jérémy, Scala, Fernanda D., Rajabi-Estarabadi, Ali, Akhundlu, Aysun, Demetrius, Dana-Lee, Gherardini, Jennifer, Keren, Aviad, Harries, Matthew, Rodriguez-Feliz, Jose, Epstein, Gorana, Lee, Wendy, Purba, Talveen, Gilhar, Amos, Paus, Ralf

Source: In Journal of Autoimmunity May 2024 145

Human epithelial stem cell survival within their niche requires 'tonic' cannabinoid receptor 1‐signalling—Lessons from the hair follicle

Authors: Sugawara, Koji, Zákány, Nóra, Tiede, Stephan, Purba, Talveen, Harries, Matthew, Tsuruta, Daisuke, Bíró, Tamás, Paus, Ralf

Source: Experimental dermatology. 30(4):479-493

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124237384.0x000001&indx=1&recIds=ETOCvdc_100124237384.0x000001

Compartmentalised metabolic programmes in human anagen hair follicles: New targets to modulate epithelial stem cell behaviour, keratinocyte proliferation and hair follicle immune status?

Authors: Purba, Talveen S., Berriche, Leïla, Paus, Ralf

Source: Experimental dermatology. 30(5):645-651

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100120085316.0x000001&indx=1&recIds=ETOCvdc_100120085316.0x000001

Does dysfunctional autophagy contribute to immune privilege collapse and alopecia areata pathogenesis?

Authors: Hardman, Jonathan A., Nicu, Carina, Tai, Charlemagne, Harries, Matthew, Mironov, Aleksandr, Purba, Talveen S., Paus, Ralf

Source: Journal of dermatological science. 100(1):75-78

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121322392.0x000001&indx=1&recIds=ETOCvdc_100121322392.0x000001

Vascular Endothelial Growth Factor Blockade Induces Dermal Endothelial Cell Apoptosis in a Clinically Relevant Skin Organ Culture Model

Authors: Luengas-Martinez, Andrea, Hardman-Smart, Jonathan, Rutkowski, David, Purba, Talveen S., Paus, Ralf, Young, Helen S.

Source: Skin pharmacology and physiology. 33(3):110-118

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108586966.0x000001&indx=1&recIds=ETOCvdc_100108586966.0x000001

Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix

Authors: Purba, Talveen S., Brunken, Lars, Peake, Michael, Shahmalak, Asim, Chaves, Asuncion, Poblet, Enrique, Ceballos, Laura, Gandarillas, Alberto, Paus, Ralf

Source: In European Journal of Cell Biology September 2017 96(6):632-641

Activation of the integrated stress response in human hair follicles.

Authors: Pye, Derek, Scholey, Rachel, Ung, Sin, Dawson, Madoc, Shahmalak, Asim, Purba, Talveen S.

Source: PLoS ONE; 6/20/2024, Vol. 19 Issue 6, p1-15, 15p

Subject Terms: HAIR growth, HAIR follicles, TRANSCRIPTION factors, WNT signal transduction, ORGAN culture, FUEL cycle, ENERGY metabolism

Visualization of global RNA synthesis in a human (mini-) organ in situ by click chemistry

Authors: Purba, Talveen S, Marsh, Jack, Ng'andu, Kayumba, Kurinna, Svitlana, Paus, Ralf

Source: Biotechniques. 65(2):97-100

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130127314.0x000001&indx=1&recIds=ETOCvdc_100130127314.0x000001

A folliculocentric perspective of dandruff pathogenesis: Could a troublesome condition be caused by changes to a natural secretory mechanism?

Authors: Limbu, Susan L., Purba, Talveen S., Harries, Matthew, Wikramanayake, Tongyu C., Miteva, Mariya, Bhogal, Ranjit K., O'Neill, Catherine A., Paus, Ralf

Source: BioEssays. 43(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131408193.0x000001&indx=1&recIds=ETOCvdc_100131408193.0x000001

XMU-MP-1 induces growth arrest in a model human mini-organ and antagonises cell cycle-dependent paclitaxel cytotoxicity

Authors: Mitchell, Ellen, Mellor, Charlotte E. L., Purba, Talveen S.

Source: Cell division. 15(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171875857.0x000001&indx=1&recIds=ETOCvdc_100171875857.0x000001

CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia

Authors: Purba, Talveen S, Ng'andu, Kayumba, Brunken, Lars, Smart, Eleanor, Mitchell, Ellen, Hassan, Nashat, O'Brien, Aaron, Mellor, Charlotte, Jackson, Jennifer, Shahmalak, Asim, Paus, Ralf

Source: EMBO molecular medicine. 11(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090938018.0x000001&indx=1&recIds=ETOCvdc_100090938018.0x000001

A primer for studying cell cycle dynamics of the human hair follicle.

Authors: Purba, Talveen S.¹, Brunken, Lars^1,2, Hawkshaw, Nathan J.¹, Peake, Michael^1,3, Hardman, Jonathan¹, Paus, Ralf^1,4

Source: Experimental Dermatology. Sep2016, Vol. 25 Issue 9, p663-668. 6p.

Subject Terms: *CELL cycle, *HAIR follicles, *IMMUNOHISTOCHEMISTRY, *IMMUNOFLUORESCENCE, *CELL proliferation, *CELLULAR control mechanisms, *APOPTOSIS

Mapping the expression of epithelial hair follicle stem cell-related transcription factors LHX2 and SOX9 in the human hair follicle.

Authors: Purba, Talveen S.¹, Haslam, Iain S.¹, Shahmalak, Asim², Bhogal, Ranjit K.³, Paus, Ralf^1,4

Source: Experimental Dermatology. Jun2015, Vol. 24 Issue 6, p462-467. 6p.

Subject Terms: *HAIR follicles, *TRANSCRIPTION factors, *PROTEIN expression, *CELL populations, *IMMUNOSTAINING

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Visualization of global RNA synthesis in a human (mini-) organ in situby click chemistry

Authors: Purba, Talveen S, Marsh, Jack, Ng'andu, Kayumba, Kurinna, Svitlana, Paus, Ralf

Source: Biotechniques; August 2018, Vol. 65 Issue: 2 p97-100, 4p

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