Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Authors: Summers, Robert L., Pasaje, Charisse Flerida A., Pisco, Joao P., Striepen, Josefine, Luth, Madeline R., Kumpornsin, Krittikorn, Carpenter, Emma F., Munro, Justin T., Lin, De, Plater, Andrew, Punekar, Avinash S., Shepherd, Andrew M., Shepherd, Sharon M., Vanaerschot, Manu, Murithi, James M., Rubiano, Kelly, Akidil, Aslı, Ottilie, Sabine, Mittal, Nimisha, Dilmore, A. Hazel, Won, Madalyn, Mandt, Rebecca E.K., McGowen, Kerry, Owen, Edward, Walpole, Chris, Llinás, Manuel, Lee, Marcus C.S., Winzeler, Elizabeth A., Fidock, David A., Gilbert, Ian H., Wirth, Dyann F., Niles, Jacquin C., Baragaña, Beatriz, Lukens, Amanda K.

Source: In Cell Chemical Biology 17 February 2022 29(2):191-201

Structures of heat shock factor trimers bound to DNA

Authors: Feng, Na, Feng, Han, Wang, Sheng, Punekar, Avinash S., Ladenstein, Rudolf, Wang, Da-Cheng, Zhang, Qinghua, Ding, Jingjin, Liu, Wei

Source: In iScience 24 September 2021 24(9)

Substrate and Stereochemical Control of Peptidoglycan Cross-Linking by Transpeptidation by Escherichia coli PBP1B

Authors: Catherwood, Anita C., Lloyd, Adrian J., Tod, Julie A., Chauhan, Smita, Slade, Susan E., Walkowiak, Grzegorz P., Galley, Nicola F., Punekar, Avinash S., Smart, Katie, Rea, Dean

Source: Journal of the American Chemical Society. 142(11):5034-5048

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623870957&indx=1&recIds=ETOCRN623870957

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization

Authors: Punekar, Avinash S., Samsudin, Firdaus, Lloyd, Adrian J., Dowson, Christopher G., Scott, David J., Khalid, Syma, Roper, David I.

Source: In The Cell Surface June 2018 2:54-66

Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity.

Authors: Green, Simon R., Wilson, Caroline, Eadsforth, Thomas C., Punekar, Avinash S., Tamaki, Fabio K., Wood, Gavin, Caldwell, Nicola, Forte, Barbara, Norcross, Neil R., Kiczun, Michael, Post, John M., Lopez-Román, Eva Maria, Engelhart, Curtis A., Lukac, Iva, Zuccotto, Fabio, Epemolu, Ola, Boshoff, Helena I. M., Schnappinger, Dirk, Walpole, Chris, Gilbert, Ian H.

Source: Journal of Medicinal Chemistry; 11/23/2023, Vol. 66 Issue 22, p15380-15408, 29p

Energetic Pathway Sampling in a Protein Interaction Domain

Authors: Hultqvist, Greta, Haq, S. Raza, Punekar, Avinash S., Chi, Celestine N., Engström, Åke, Bach, Anders, Strømgaard, Kristian, Selmer, Maria, Gianni, Stefano, Jemth, Per

Source: In Structure 2 July 2013 21(7):1193-1202

Tolerance of Protein Folding to a Circular Permutation in a PDZ Domain.

Authors: Hultqvist, Greta¹ (AUTHOR), Punekar, Avinash S.² (AUTHOR), Morrone, Angela³ (AUTHOR), Chi, Celestine N.¹ (AUTHOR), Engström, Åke¹ (AUTHOR), Selmer, Maria² (AUTHOR) Maria.Selmer@icm.uu.se, Gianni, Stefano³ (AUTHOR) Stefano.Gianni@uniroma1.it, Jemth, Per¹ (AUTHOR) Per.Jemth@imbim.uu.se

Source: PLoS ONE. Nov2012, Vol. 7 Issue 11, Special section p1-11. 11p.

Subject Terms: *RHODOPSIN, *CHLAMYDOMONAS reinhardtii, *PROTEINS, *ION pumps, *ION channels, *ALKALI metals, *VOLTAGE-clamp techniques (Electrophysiology)

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Structure-Guided Enhancement of Selectivity of Chemical Probe Inhibitors Targeting Bacterial Seryl-tRNA Synthetase

Authors: Cain, Ricky, Salimraj, Ramya, Punekar, Avinash S., Bellini, Dom, Fishwick, Colin W. G., Czaplewski, Lloyd, Scott, David J., Harris, Gemma, Dowson, Christopher G., Lloyd, Adrian J., Roper, David I.

Source: Journal of Medicinal Chemistry; November 2019, Vol. 62 Issue: 21 p9703-9717, 15p

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Crystal structure of RlmM, the 2′O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA.

Authors: Punekar, Avinash S., Shepherd, Tyson R., Liljeruhm, Josefine, Forster, Anthony C., Selmer, Maria

Source: Nucleic Acids Research; Nov2012, Vol. 40 Issue 20, p10507-10520, 14p

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