The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

Authors: Pundhir, Sachin, Su, Jinyu, Tapia, Marta, Hansen, Anne Meldgaard, Haile, James Seymour, Hansen, Klaus, Porse, Bo Torben

Source: Genome research. 33(3):332-345

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631862572&indx=1&recIds=ETOCRN631862572

PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents

Authors: Rehn, Matilda, Wenzel, Anne, Frank, Anne-Katrine, Schuster, Mikkel Bruhn, Pundhir, Sachin, Jørgensen, Nanna, Vitting-Seerup, Kristoffer, Ge, Ying, Jendholm, Johan, Michaut, Magali, Schoof, Erwin M., Jensen, Tanja Lyholm, Rapin, Nicolas, Sapio, Russell T., Andersen, Kasper Langebjerg, Lund, Anders H., Solimena, Michele, Holzenberger, Martin, Pestov, Dimitri G., Porse, Bo Torben

Source: In Cell Reports 10 May 2022 39(6)

Ancestrally Duplicated Conserved Noncoding Element Suggests Dual Regulatory Roles of HOTAIR in cis and trans

Authors: Nepal, Chirag, Taranta, Andrzej, Hadzhiev, Yavor, Pundhir, Sachin, Mydel, Piotr, Lenhard, Boris, Müller, Ferenc, Andersen, Jesper B.

Source: In iScience 24 April 2020 23(4)

Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment

Authors: Lauridsen, Felicia Kathrine Bratt, Jensen, Tanja Lyholm, Rapin, Nicolas, Aslan, Derya, Wilhelmson, Anna Sofia, Pundhir, Sachin, Rehn, Matilda, Paul, Franziska, Giladi, Amir, Hasemann, Marie Sigurd, Serup, Palle, Amit, Ido, Porse, Bo Torben

Source: In Cell Reports 17 July 2018 24(3):766-780

Enhancer and Transcription Factor Dynamics during Myeloid Differentiation Reveal an Early Differentiation Block in Cebpa null Progenitors

Authors: Pundhir, Sachin, Bratt Lauridsen, Felicia Kathrine, Schuster, Mikkel Bruhn, Jakobsen, Janus Schou, Ge, Ying, Schoof, Erwin Marten, Rapin, Nicolas, Waage, Johannes, Hasemann, Marie Sigurd, Porse, Bo Torben

Source: In Cell Reports 29 May 2018 23(9):2744-2757

The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

Authors: Ge, Ying, Schuster, Mikkel, Pundhir, Sachin, Rapin, Nicolas, Bagger, Frederik, Sidiropoulos, Nikos, Hashem, Nadia, Porse, Bo

Source: Nature communications. 10(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103851506.0x000001&indx=1&recIds=ETOCvdc_100103851506.0x000001

TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression.

Authors: Heyes, Elizabeth, Wilhelmson, Anna S., Wenzel, Anne, Manhart, Gabriele, Eder, Thomas, Schuster, Mikkel B., Rzepa, Edwin, Pundhir, Sachin, D'Altri, Teresa, Frank, Anne-Katrine, Gentil, Coline, Woessmann, Jakob, Schoof, Erwin M., Meggendorfer, Manja, Schwaller, Jürg, Haferlach, Torsten, Grebien, Florian, Porse, Bo T.

Source: Nature Communications; 10/4/2023, Vol. 14 Issue 1, p1-18, 18p

Subject Terms: ACUTE myeloid leukemia, TRANSCRIPTION factors

The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

Authors: Trempenau, Mette Louise, Schuster, Mikkel Bruhn, Pundhir, Sachin, Pereira, Mafalda Araujo, Kalvisa, Adrija, Tapia, Marta, Su, Jinyu, Ge, Ying, de Boer, Bauke, Balhuizen, Alexander, Bagger, Frederik Otzen, Shliaha, Pavel, Sroczynska, Patrycja, Walfridsson, Julian, Grønbæk, Kirsten, Theilgaard-Mönch, Kim, Jensen, Ole N., Helin, Kristian, Porse, Bo T.

Source: Leukemia; March 2023, Vol. 37 Issue: 3 p593-605, 13p

Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard.

Authors: Theilgaard-Mönch, Kim, Pundhir, Sachin, Reckzeh, Kristian, Su, Jinyu, Tapia, Marta, Furtwängler, Benjamin, Jendholm, Johan, Jakobsen, Janus Schou, Hasemann, Marie Sigurd, Knudsen, Kasper Jermiin, Cowland, Jack Bernard, Fossum, Anna, Schoof, Erwin, Schuster, Mikkel Bruhn, Porse, Bo T.

Source: Nature Communications; 6/23/2022, Vol. 13 Issue 1, p1-17, 17p

Subject Terms: CELL cycle, MULTIPOTENT stem cells, HEMATOPOIETIC stem cells, MYC oncogenes, BLOOD cells

EssOilDB: a database of essential oils reflecting terpene composition and variability in the plant kingdom.

Authors: Kumari, Sangita¹ (AUTHOR), Pundhir, Sachin¹ (AUTHOR), Priya, Piyush¹ (AUTHOR), Jeena, Ganga¹ (AUTHOR), Punetha, Ankita¹ (AUTHOR), Chawla, Konika¹ (AUTHOR), Jafaree, Zohra Firdos¹ (AUTHOR), Mondal, Subhasish¹ (AUTHOR), Yadav, Gitanjali¹ (AUTHOR) gy@nipgr.ac.in

Source: Database: The Journal of Biological Databases & Curation. 2014, Vol. 2014, p1-12. 12p. 1 Color Photograph, 2 Diagrams, 1 Chart, 3 Graphs.

PredictBias: A Server for the Identification of Genomic and Pathogenicity Islands in Prokaryotes.

Authors: Pundhir, Sachin¹, Vijayvargiya, Hemant¹, Kumar, Anil¹ ak.sbt@yahoo.com

Source: In Silico Biology. 2008, Vol. 8 Issue 3/4, p223-234. 12p. 1 Black and White Photograph, 2 Diagrams, 3 Charts, 1 Graph.

Subject Terms: *GENETIC transformation, *MICROBIAL virulence, *PROKARYOTES, *HUMAN gene mapping, *PROTEIN binding, *SCIENTIFIC method

The splice factor PTBP1 regulates hematopoietic stem cell function and red blood cell development

Authors: Rehn, Matilda, Frank, Anne-Katrine, Pundhir, Sachin, Rapin, Nicolas, Ge, Ying, Jendholm, Johan, Jensen, Tanja, Solimena, Michele, Porse, Bo

Source: Experimental hematology. 44:S95-S96

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100036097894.0x000001&indx=1&recIds=ETOCvdc_100036097894.0x000001

Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism.

Authors: Jacobsen, Mette Juul, Havgaard, Jakob H., Anthon, Christian, Mentzel, Caroline M. Junker, Cirera, Susanna, Krogh, Poula Maltha, Pundhir, Sachin, Karlskov-Mortensen, Peter, Bruun, Camilla S., Lesnik, Philippe, Guerin, Maryse, Gorodkin, Jan, Jørgensen, Claus B., Fredholm, Merete, Barrès, Romain

Source: Frontiers in Genetics; 12/17/2019, Vol. 10, p1-13, 13p

Subject Terms: METABOLIC regulation, ADIPOGENESIS, EPIGENETICS, SWINE, DNA methylation, METABOLIC disorders, BINDING sites

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Bloodspot: A Web Resource Facilitating the Analysis of Transcriptional Programs in Normal and Malignant Hematopoiesis

Authors: Bagger, Frederik Otzen ^*, Sasivarevic, Damir ^*, Sohi, Sina Hadi ^*, Laursen, Linea Gøricke ^*, Pundhir, Sachin ^*, Winther, Ole ^*, Rapin, Nicolas ^*, Porse, Bo T ^*

Source: In Blood 3 December 2015 126(23):2358-2358