RluA is the major mRNA pseudouridine synthase in Escherichia coli.

Authors: Schaening-Burgos, Cassandra^1,2 (AUTHOR), LeBlanc, Hannah¹ (AUTHOR), Fagre, Christian³ (AUTHOR), Li, Gene-Wei¹ (AUTHOR) gwli@mit.edu, Gilbert, Wendy V.³ (AUTHOR) wendy.gilbert@yale.edu

Source: PLoS Genetics. 9/6/2024, Vol. 20 Issue 9, p1-21. 21p.

Subject Terms: *RNA modification & restriction, *PSEUDOURIDINE, *ESCHERICHIA coli, *GENE expression, *MESSENGER RNA, *TRANSFER RNA

Fuzzy kernel evidence Random Forest for identifying pseudouridine sites.

Authors: Chen, Mingshuai^1,2 (AUTHOR), Sun, Mingai³ (AUTHOR), Su, Xi⁴ (AUTHOR), Tiwari, Prayag⁵ (AUTHOR) prayag.tiwari@ieee.org, Ding, Yijie² (AUTHOR) prayag.tiwari@ieee.org

Source: Briefings in Bioinformatics. May2024, Vol. 25 Issue 3, p1-14. 14p.

Subject Terms: Pseudouridine, Random forest algorithms, RNA modification & restriction, Uridine, RNA sequencing, Fuzzy logic

The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1.

Authors: Grünberg, Sebastian¹ (AUTHOR) sgruenberg@neb.com, Doyle, Lindsey A.² (AUTHOR), Wolf, Eric J.¹ (AUTHOR), Dai, Nan¹ (AUTHOR), Corrêa Jr., Ivan R.¹ (AUTHOR), Yigit, Erbay¹ (AUTHOR) sgruenberg@neb.com, Stoddard, Barry L.² (AUTHOR)

Source: PLoS ONE. 11/8/2023, Vol. 18 Issue 11, p1-24. 24p.

Subject Terms: *PSEUDOURIDINE, *RNA modification & restriction, *MESSENGER RNA, *CATALYTIC RNA, *TRANSFER RNA, *NON-coding RNA

Higher expression of pseudouridine synthase 7 promotes non-small cell lung cancer progression and suggests a poor prognosis.

Authors: Zhang, Guihong¹ (AUTHOR), Zhu, Yongde² (AUTHOR), Tan, Yonghuang¹ (AUTHOR), Chen, Biao³ (AUTHOR), Shan, Shichao¹ (AUTHOR), Zhang, Gengyu⁴ (AUTHOR), Lu, Jianjun¹ (AUTHOR) Lujj@mail.sysu.edu.cn

Source: Journal of Cardiothoracic Surgery. 7/7/2023, Vol. 18 Issue 1, p1-8. 8p.

Subject Terms: *NON-small-cell lung carcinoma, *PSEUDOURIDINE, *CANCER invasiveness, *IMMUNOSTAINING, *PROGNOSIS

PseU-KeMRF: A Novel Method for Identifying RNA Pseudouridine Sites

Authors: Chen, M., Zou, Q., Qi, R., Ding, Y.

Source: IEEE/ACM Transactions on Computational Biology and Bioinformatics IEEE/ACM Trans. Comput. Biol. and Bioinf. Computational Biology and Bioinformatics, IEEE/ACM Transactions on. 21(5):1423-1435 Jan, 2024

N¹-methyl-pseudouridine is incorporated with higher fidelity than pseudouridine in synthetic RNAs.

Authors: Chen, Tien-Hao¹ (AUTHOR), Potapov, Vladimir¹ (AUTHOR), Dai, Nan¹ (AUTHOR), Ong, Jennifer L.¹ (AUTHOR), Roy, Bijoyita¹ (AUTHOR) broy@neb.com

Source: Scientific Reports. 7/29/2022, Vol. 12 Issue 1, p1-13. 13p.

Subject Terms: *PSEUDOURIDINE, *NUCLEOTIDE sequence, *RNA polymerases, *URIDINE, *RNA, *MESSENGER RNA

The plant epitranscriptome: revisiting pseudouridine and 2′‐O‐methyl RNA modifications.

Authors: Ramakrishnan, Muthusamy^1,2 (AUTHOR) ramky@zafu.edu.cn, Rajan, K. Shanmugha^3,4 (AUTHOR) kshanmugharajan101@gmail.com, Mullasseri, Sileesh⁵ (AUTHOR), Palakkal, Sarin⁶ (AUTHOR) sarinpalakkal@gmail.com, Kalpana, Krishnan⁷ (AUTHOR), Sharma, Anket⁸ (AUTHOR), Zhou, Mingbing^8,9 (AUTHOR), Vinod, Kunnummal Kurungara¹⁰ (AUTHOR), Ramasamy, Subbiah¹¹ (AUTHOR) subbiahr@nrcbsmku.org, Wei, Qiang^1,2 (AUTHOR) weiqiang@njfu.edu.cn

Source: Plant Biotechnology Journal. Jul2022, Vol. 20 Issue 7, p1241-1256. 16p.

Subject Terms: *RNA modification & restriction, *PSEUDOURIDINE, *FRUIT ripening, *ROOT development, *ADENOSINES, *PLANT development, *URIDINE

Arabidopsis Mitochondrial Pseudouridine Synthase Homolog FCS1 Plays Critical Roles in Plant Development.

Authors: Niu, Yanli¹ (AUTHOR), Zheng, Yuan¹ (AUTHOR), Zhu, Huijie¹ (AUTHOR), Zhao, Hongyun¹ (AUTHOR), Nie, Kaili¹ (AUTHOR), Wang, Xiaopei¹ (AUTHOR), Sun, Lirong¹ (AUTHOR), Song, Chun-Peng¹ (AUTHOR) songcp@henu.edu.cn

Source: Plant & Cell Physiology. Jul2022, Vol. 63 Issue 7, p955-966. 12p.

Subject Terms: *PLANT mitochondria, *PSEUDOURIDINE, *PLANT development, *MITOCHONDRIA, *IMMOBILIZED proteins, *RNA modification & restriction, *URIDINE

Efficient Synthetic Access to Stable Isotope Labelled Pseudouridine Phosphoramidites for RNA NMR Spectroscopy.

Authors: Glänzer, David¹ (AUTHOR), Pfeiffer, Martin^2,3 (AUTHOR), Ribar, Andrej^2,3 (AUTHOR), Zeindl, Ricarda¹ (AUTHOR), Tollinger, Martin¹ (AUTHOR), Nidetzky, Bernd^2,3 (AUTHOR) bernd.nidetzky@tugraz.at, Kreutz, Christoph¹ (AUTHOR) christoph.kreutz@uibk.ac.at

Source: Chemistry - A European Journal. 6/25/2024, Vol. 30 Issue 36, p1-8. 8p.

Subject Terms: *PSEUDOURIDINE, *RADIOLABELING, *RNA, *PHOSPHORAMIDITES, *ESCHERICHIA coli, *URIDINE

OsPPG encodes a pseudouridine-50 -phosphate glycosidase and regulates rice spikelet development.

Authors: Rui Chen^1,2, Dagang Tian², Yarong Lin², Jiaqing Huang³, Qinqin Yang¹, Yupei Li^1,2, Huaqing Liu², Shaohua Yang², Jingyang Chen², Shufen Zhou², Feng Wang² wf@fjage.org, Shubiao Zhang¹ zhangsbiao@aliyun.com

Source: Crop Journal (2095-5421). Jun2024, Vol. 12 Issue 3, p698-708. 11p.

Subject Terms: *PSEUDOURIDINE, *GLYCOSIDASES, *RICE, *STAMEN, *MORPHOGENESIS

Locus-specific detection of pseudouridine with CRISPR-Cas13a.

Authors: Sun, Mei¹ (AUTHOR), Fang, Xin¹ (AUTHOR), Lin, Bingqian¹ (AUTHOR), Mo, Jing¹ (AUTHOR), Wang, Fang² (AUTHOR), Zhou, Xiang^1,3 (AUTHOR), Weng, Xiaocheng¹ (AUTHOR) xcweng@whu.edu.cn

Source: Chemical Communications. 4/18/2024, Vol. 60 Issue 30, p4088-4091. 4p.

Subject Terms: *PSEUDOURIDINE, *SMALL nuclear RNA, *RIBOSOMAL RNA, *TELEMATICS, *MESSENGER RNA, *RIBOSOMAL DNA, CHEMICAL labeling

PseUpred-ELPSO Is an Ensemble Learning Predictor with Particle Swarm Optimizer for Improving the Prediction of RNA Pseudouridine Sites.

Authors: Wang, Xiao^1,2 (AUTHOR) wangxiao@zzuli.edu.cn, Li, Pengfei¹ (AUTHOR) 332107040630@email.zzuli.edu.cn, Wang, Rong³ (AUTHOR) wangrong@zzuli.edu.cn, Gao, Xu⁴ (AUTHOR) gaoxu@zzu.edu.cn

Source: Biology (2079-7737). Apr2024, Vol. 13 Issue 4, p248. 16p.

Subject Terms: *PSEUDOURIDINE, *RNA modification & restriction, *GENE expression, *RNA, *NON-coding RNA, *URIDINE

Porpoise: a new approach for accurate prediction of RNA pseudouridine sites.

Authors: Li, Fuyi¹ (AUTHOR) fuyi.li@unimelb.edu.au, Guo, Xudong² (AUTHOR), Jin, Peipei³ (AUTHOR), Chen, Jinxiang⁴ (AUTHOR), Xiang, Dongxu⁵ (AUTHOR), Song, Jiangning⁶ (AUTHOR) fuyi.li@unimelb.edu.au, Coin, Lachlan J M⁷ (AUTHOR) fuyi.li@unimelb.edu.au

Source: Briefings in Bioinformatics. Nov2021, Vol. 22 Issue 6, p1-12. 12p.

Subject Terms: Pseudouridine, Porpoises, Uridine, Nucleotide sequence, RNA, RNA modification & restriction

Data-informed reparameterization of modified RNA and the effect of explicit water models: application to pseudouridine and derivatives.

Authors: Dutta, Nivedita¹ (AUTHOR), Deb, Indrajit¹ (AUTHOR), Sarzynska, Joanna² (AUTHOR), Lahiri, Ansuman¹ (AUTHOR) albmbg@caluniv.ac.in

Source: Journal of Computer-Aided Molecular Design. Mar2022, Vol. 36 Issue 3, p205-224. 20p.

Subject Terms: *PSEUDOURIDINE, *URIDINE, *RNA, *ATOMIC charges, *RNA modification & restriction, *NUCLEOSIDES

The uridine to pseudouridine modification at the wobble position of eukaryotic isoleucine tRNA species is unlikely to induce mistranslation.

Authors: Takai, Kazuyuki¹ (AUTHOR)

Source: Nucleosides, Nucleotides & Nucleic Acids. 2022, Vol. 41 Issue 2, p137-153. 17p.

Subject Terms: *TRANSFER RNA, *PSEUDOURIDINE, *URIDINE, *BASE pairs, *ISOLEUCINE, *STACKING interactions

Assessing the relationships of 1,400 blood metabolites with abdominal aortic aneurysm: a Mendelian randomization study.

Authors: Guo, Qian, Xu, Xinghua, Li, Xiaohui, Mao, Yang, Li, Shengqiang, Yao, Yuxin, Li, Xiang, Li, Yaxing, Feng, Jiayue, Shu, Yan, Xu, Xingli

Source: Frontiers in Pharmacology; 2025, p1-11, 11p

Subject Terms: ABDOMINAL aortic aneurysms, MENDELIAN randomization, PSEUDOURIDINE, METABOLIC disorders, VASCULAR diseases

Promoted read-through and mutation against pseudouridine-CMC by an evolved reverse transcriptase.

Authors: He, Zhiyong, Qiu, Weiqi, Zhou, Huiqing

Source: Communications Biology; 1/11/2025, Vol. 8 Issue 1, p1-11, 11p

Subject Terms: REVERSE transcriptase, RNA modification & restriction, CHEMICAL labeling, PSEUDOURIDINE, REVERSE engineering

Development and Evaluation of the Immunogenic Potential of an Unmodified Nucleoside mRNA Vaccine for Herpes Zoster.

Authors: Zhang, Shun, Wang, Xiaojie, Zhao, Tongyi, Yang, Chen, Huang, Lulu

Source: Vaccines; Jan2025, Vol. 13 Issue 1, p68, 12p

Subject Terms: HERPES zoster vaccines, VACCINE immunogenicity, VARICELLA-zoster virus, VACCINE approval, PSEUDOURIDINE

Implications of RNA pseudouridylation for cancer biology and therapeutics: a narrative review

Authors: Hanyi Ding, Na Liu, Yan Wang, Sofia Abdulkadir Adam, Jie Jin, Weiying Feng, Jie Sun

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)

Subject Terms: Pseudouridine, RNA modification, Pseudouridine synthase, Cancer diagnosis, Cancer treatment, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/8bf37b97aefb46e2aa69dbc66cb0ef2c

Tubular dysfunction impairs renal excretion of pseudouridine in diabetic kidney disease.

Authors: Mathew, Anna V.¹, Kayampilly, Pradeep¹, Byun, Jaeman¹, Nair, Viji¹, Afshinnia, Farsad¹, Biaoxin Chai¹, Brosius 3rd, Frank C.^1,2, Kretzler, Matthias¹, Pennathur, Subramaniam^1,3 spennath@umich.edu

Source: American Journal of Physiology: Renal Physiology. Jan2024, Vol. 326 Issue 1, pF30-F38. 9p.

Subject Terms: *DIABETIC nephropathies, *PSEUDOURIDINE, *METABOLIC flux analysis, *KIDNEY diseases, *LIQUID chromatography-mass spectrometry