Novel access to α-carbolines with biological applications

Authors: Provot, Olivier

Source: In European Journal of Medicinal Chemistry 5 October 2024 276

Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors

Authors: Hauguel, Camille, Ducellier, Sarah, Provot, Olivier, Ibrahim, Nada, Lamaa, Diana, Balcerowiak, Coline, Letribot, Boris, Nascimento, Megane, Blanchard, Vincent, Askenatzis, Laurie, Levaique, Helene, Bignon, Jérôme, Baschieri, Francesco, Bauvais, Cyril, Bollot, Guillaume, Renko, Dolor, Deroussent, Alain, Prost, Bastien, Laisne, Marie-Catherine, Michallet, Sophie, Lafanechère, Laurence, Papot, Sébastien, Montagnac, Guillaume, Tran, Christine, Alami, Mouad, Apcher, Sebastien, Hamze, Abdallah

Source: In European Journal of Medicinal Chemistry 5 October 2022 240

Synthesis of Oxazino[4,3-a]indoles and biological applications

Authors: Pecnard, Shannon, Hamze, Abdallah, Pozzo, Jean-Luc, Alami, Mouad, Provot, Olivier

Source: In European Journal of Medicinal Chemistry 15 November 2021 224

Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues

Authors: Pecnard, Shannon, Hamze, Abdallah, Bignon, Jérome, Prost, Bastien, Deroussent, Alain, Gallego-Yerga, Laura, Peláez, Rafael, Paik, Ji Yeon, Diederich, Marc, Alami, Mouad, Provot, Olivier

Source: In European Journal of Medicinal Chemistry 5 November 2021 223

Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation

Authors: Pecnard, Shannon, Provot, Olivier, Levaique, Hélène, Bignon, Jérome, Askenatzis, Laurie, Saller, Francois, Borgel, Delphine, Michallet, Sophie, Laisne, Marie-Catherine, Lafanechère, Laurence, Alami, Mouad, Hamze, Abdallah

Source: In European Journal of Medicinal Chemistry 1 January 2021 209

Developments of isoCombretastatin A-4 derivatives as highly cytotoxic agents

Authors: Hamze, Abdallah, Alami, Mouad, Provot, Olivier

Source: In European Journal of Medicinal Chemistry 15 March 2020 190

N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents

Authors: Khelifi, Ilhem, Naret, Timothée, Hamze, Abdallah, Bignon, Jérome, Levaique, Hélène, Garcia Alvarez, Maria Concepcion, Dubois, Joëlle, Provot, Olivier, Alami, Mouad

Source: In European Journal of Medicinal Chemistry 15 April 2019 168:176-188

Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors

Authors: Khelifi, Ilhem, Naret, Timothée, Renko, Dolor, Hamze, Abdallah, Bernadat, Guillaume, Bignon, Jérome, Lenoir, Christine, Dubois, Joëlle, Brion, Jean-Daniel, Provot, Olivier, Alami, Mouad

Source: In European Journal of Medicinal Chemistry 15 February 2017 127:1025-1034

Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents

Authors: Renko, Dolor, Provot, Olivier, Rasolofonjatovo, Evelia, Bignon, Jérôme, Rodrigo, Jordi, Dubois, Joëlle, Brion, Jean-Daniel, Hamze, Abdallah, Alami, Mouad

Source: In European Journal of Medicinal Chemistry 27 January 2015 90:834-844

Discovery of azaisoerianin derivatives as potential antitumors agents

Authors: Soussi, Mohamed Ali, Provot, Olivier, Bernadat, Guillaume, Bignon, Jérome, Wdzieczak-Bakala, Joanna, Desravines, Déborah, Dubois, Joëlle, Brion, Jean-Daniel, Messaoudi, Samir, Alami, Mouad

Source: In European Journal of Medicinal Chemistry 6 May 2014 78:178-189

Recent advances in the synthesis of dibenzofurans.

Authors: Alami, Mouad, Provot, Olivier

Source: Organic & Biomolecular Chemistry; 2/21/2024, Vol. 22 Issue 7, p1323-1345, 23p

Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs

Authors: Rasolofonjatovo, Evelia, Provot, Olivier, Hamze, Abdallah, Rodrigo, Jordi, Bignon, Jérome, Wdzieczak-Bakala, Joanna, Lenoir, Christine, Desravines, Déborah, Dubois, Joëlle, Brion, Jean-Daniel, Alami, Mouad

Source: In European Journal of Medicinal Chemistry April 2013 62:28-39

Synthesis of Aza‐Heterocyclic Compounds with N‐Tosylhydrazones: Formation of Bi‐Indoles via Reductive Molybdenum Catalysis.

Authors: Liu, Xinya¹ (AUTHOR), Provot, Olivier¹ (AUTHOR), Franco, Remi¹ (AUTHOR), Retailleau, Pascal² (AUTHOR), Alami, Mouad¹ (AUTHOR), Gandon, Vincent³ (AUTHOR), Tran, Christine¹ (AUTHOR), Hamze, Abdallah¹ (AUTHOR) abdallah.hamze@universite-paris-saclay.fr

Source: Advanced Synthesis & Catalysis. 9/19/2023, Vol. 365 Issue 18, p3155-3161. 7p.

Subject Terms: *MOLYBDENUM, *CATALYSIS, *CARBAZOLE derivatives, *INDOLE, *AZA compounds, *MOLYBDENUM compounds, *HETEROCYCLIC compounds

Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: Synthesis, cytotoxicity and antitubulin activity

Authors: Rasolofonjatovo, Evelia, Provot, Olivier, Hamze, Abdallah, Rodrigo, Jordi, Bignon, Jérome, Wdzieczak-Bakala, Joanna, Desravines, Déborah, Dubois, Joëlle, Brion, Jean-Daniel, Alami, Mouad

Source: In European Journal of Medicinal Chemistry June 2012 52:22-32

Hydration of Unsymmetrical Internal Alkynes: Factors Governing the Regioselectivity.

Authors: Liu, Xinya¹ (AUTHOR), Pozzo, Jean-Luc² (AUTHOR), Hamze, Abdallah¹ (AUTHOR), Alami, Mouad¹ (AUTHOR) mouad.alami@universite-paris-saclay.fr, Provot, Olivier¹ (AUTHOR) olivier.provot@universite-paris-saclay.fr

Source: ACS Catalysis. 8/4/2023, Vol. 13 Issue 15, p10115-10136. 22p.

Regioselective hydrostannation of diarylalkynes directed by a labile ortho bromine atom: An easy access to stereodefined triarylolefins, hybrids of combretastatin A-4 and isocombretastatin A-4

Authors: Rasolofonjatovo, Evelia, Provot, Olivier, Hamze, Abdallah, Bignon, Jérome, Thoret, Sylviane, Brion, Jean-Daniel, Alami, Mouâd

Source: In European Journal of Medicinal Chemistry 2010 45(9):3617-3626

Regioselective hydrostannation of highly hindered arylalkynes under ortho-directing effects

Authors: Hamze, Abdallah, Le Menez, Patrick, Provot, Olivier, Morvan, Estelle, Brion, Jean-Daniel, Alami, Mouâd

Source: In Tetrahedron 2010 66(45):8698-8706

p-Toluenesulfonic acid-promoted selective functionalization of unsymmetrical arylalkynes: a regioselective access to various arylketones and heterocycles

Authors: Jacubert, Maud, Provot, Olivier, Peyrat, Jean-François, Hamze, Abdallah, Brion, Jean-Daniel, Alami, Mouâd

Source: In Tetrahedron 2010 66(21):3775-3787

DMSO–PdI 2 as a powerful oxidizing couple of alkynes into benzils: one-pot synthesis of nitrogen-containing five- or six-membered heterocycles

Authors: Mousset, Céline, Provot, Olivier, Hamze, Abdallah, Bignon, Jérôme, Brion, Jean-Daniel, Alami, Mouâd

Source: In Tetrahedron 2008 64(19):4287-4294

Xphos ligand and platinum catalysts: A versatile catalyst for the synthesis of functionalized β-( E)-vinylsilanes from terminal alkynes

Authors: Hamze, Abdallah, Provot, Olivier, Brion, Jean-Daniel, Alami, Mouâd

Source: In Journal of Organometallic Chemistry 2008 693(16):2789-2797