Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum

Authors: Alruwaili, Muharib, Elahi, Rubayet, van Schalkwyk, Donelly, Sutherland, Colin, Shapiro, Theresa, Prigge, Sean, Sullivan, David

Source: American journal of tropical medicine and hygiene. 108(4):777-782

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN631915669&indx=1&recIds=ETOCRN631915669

New insights into apicoplast metabolism in blood-stage malaria parasites

Authors: Elahi, Rubayet, Prigge, Sean T

Source: In Current Opinion in Microbiology February 2023 71

The ferredoxin redox system – an essential electron distributing hub in the apicoplast of Apicomplexa

Authors: Akuh, Ojo-Ajogu, Elahi, Rubayet, Prigge, Sean T., Seeber, Frank

Source: Trends in parasitology. 38(10):868-881

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169913405.0x000001&indx=1&recIds=ETOCvdc_100169913405.0x000001

Metabolic changes accompanying the loss of fumarate hydratase and malate–quinone oxidoreductase in the asexual blood stage of Plasmodium falciparum

Authors: Rajaram, Krithika, Tewari, Shivendra G., Wallqvist, Anders, Prigge, Sean T.

Source: In Journal of Biological Chemistry May 2022 298(5)

A Chemical Proteomic Strategy Reveals Inhibitors of Lipoate Salvage in Bacteria and Parasites

Authors: Dienemann, Jan‐Niklas, Chen, Shu‐Yu, Hitzenberger, Manuel, Sievert, Montana L., Hacker, Stephan M., Prigge, Sean T., Zacharias, Martin, Groll, Michael, Sieber, Stephan A.

Source: Angewandte Chemie international edition. 62(31)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190294594.0x000001&indx=1&recIds=ETOCvdc_100190294594.0x000001

Eine chemisch‐proteomische Strategie identifiziert Inhibitoren der Lipoat‐Wiederverwertung in Bakterien und Parasiten

Authors: Dienemann, Jan‐Niklas, Chen, Shu‐Yu, Hitzenberger, Manuel, Sievert, Montana L., Hacker, Stephan M., Prigge, Sean T., Zacharias, Martin, Groll, Michael, Sieber, Stephan A.

Source: Angewandte Chemie. 135(31)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189382703.0x000001&indx=1&recIds=ETOCvdc_100189382703.0x000001

Development of a conditional localization approach to control apicoplast protein trafficking in malaria parasites

Authors: Roberts, Aleah D., Nair, Sethu C., Guerra, Alfredo J., Prigge, Sean T.

Source: Traffic. 20(8):571-582

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100102946135.0x000001&indx=1&recIds=ETOCvdc_100102946135.0x000001

Short-term metabolic adjustments in Plasmodium falciparum counter hypoxanthine deprivation at the expense of long-term viability

Authors: Tewari, Shivendra, Rajaram, Krithika, Schyman, Patric, Swift, Russell, Reifman, Jaques, Prigge, Sean, Wallqvist, Anders

Source: Malaria journal. 18(1):1-13

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186556175.0x000001&indx=1&recIds=ETOCvdc_100186556175.0x000001

Host biotin is required for liver stage development in malaria parasites

Authors: Dellibovi-Ragheb, Teegan A., Jhun, Hugo, Goodman, Christopher D., Walters, Maroya S., Ragheb, Daniel R. T., Matthews, Krista A., Rajaram, Krithika, Mishra, Satish, McFadden, Geoffrey I., Sinnis, Photini, Prigge, Sean T.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2018 Mar . 115(11), E2604-E2613.

Access URL: https://www.jstor.org/stable/26508361

Dioxygen Binds End-on to Mononuclear Copper in a Precatalytic Enzyme Complex

Authors: Prigge, Sean T., Eipper, Betty A., Mains, Richard E., Amzel, L. Mario

Source: Science, 2004 May 01. 304(5672), 864-867.

Access URL: https://www.jstor.org/stable/3836925

Using a genome-scale metabolic network model to elucidate the mechanism of chloroquine action in Plasmodium falciparum

Authors: Tewari, Shivendra G., Prigge, Sean T., Reifman, Jaques, Wallqvist, Anders

Source: In International Journal for Parasitology: Drugs and Drug Resistance August 2017 7(2):138-146

Amidation of Bioactive Peptides: The Structure of Peptidylglycine α- Hydroxylating Monooxygenase

Authors: Prigge, Sean T., Kolhekar, Aparna S., Eipper, Betty A., Mains, Richard E., Amzel, L. Mario

Source: Science, 1997 Nov . 278(5341), 1300-1305.

Access URL: https://www.jstor.org/stable/2894195

Dephospho‐CoA kinase, a nuclear‐encoded apicoplast protein, remains active and essential after Plasmodium falciparum apicoplast disruption

Authors: Swift, Russell P, Rajaram, Krithika, Liu, Hans B, Prigge, Sean T

Source: EMBO journal. 40(16)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100138520254.0x000001&indx=1&recIds=ETOCvdc_100138520254.0x000001

Clinically relevant atovaquone-resistant human malaria parasites fail to transmit by mosquito.

Authors: Balta, Victoria A., Stiffler, Deborah, Sayeed, Abeer, Tripathi, Abhai K., Elahi, Rubayet, Mlambo, Godfree, Bakshi, Rahul P., Dziedzic, Amanda G., Jedlicka, Anne E., Nenortas, Elizabeth, Romero-Rodriguez, Keyla, Canonizado, Matthew A., Mann, Alexis, Owen, Andrew, Sullivan, David J., Prigge, Sean T., Sinnis, Photini, Shapiro, Theresa A.

Source: Nature Communications; 10/12/2023, Vol. 14 Issue 1, p1-9, 9p

Subject Terms: PLASMODIUM, MOSQUITOES, OOCYSTS, ANOPHELES stephensi, CYTOCHROME b, LIVER cells, DRUG efficacy

Geographic Terms: SOUTHEAST Asia, AFRICA

Metabolic alterations in the erythrocyte during blood-stage development of the malaria parasite

Authors: Tewari, Shivendra G., Swift, Russell P., Reifman, Jaques, Prigge, Sean T., Wallqvist, Anders

Source: Malaria journal. 19(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164231188.0x000001&indx=1&recIds=ETOCvdc_100164231188.0x000001

The Plasmodium falciparum apicoplast cysteine desulfurase provides sulfur for both iron-sulfur cluster assembly and tRNA modification.

Authors: Swift, Russell P., Elahi, Rubayet, Rajaram, Krithika, Liu, Hans B., Prigge, Sean T.

Source: eLife; 5/26/2023, p1-33, 33p

The mitochondrion of Plasmodium falciparum is required for cellular acetyl-CoA metabolism and protein acetylation.

Authors: Nair, Sethu C., Munro, Justin T., Mann, Alexis, Llinás, Manuel, Prigge, Sean T.

Source: Proceedings of the National Academy of Sciences of the United States of America; 4/25/2023, Vol. 120 Issue 17, p1-12, 41p

Subject Terms: ACETYLCOENZYME A, PROTEIN metabolism, PLASMODIUM falciparum, MITOCHONDRIA, ACETYLATION

An update on the rapid advances in malaria parasite cell biology

Authors: Coppens, Isabelle, Sullivan, David J., Prigge, Sean T.

Source: In Trends in Parasitology 2010 26(6):305-310

Metabolic responses in blood-stage malaria parasites associated with increased and decreased sensitivity to PfATP4 inhibitors.

Authors: Tewari, Shivendra G., Elahi, Rubayet, Kwan, Bobby, Rajaram, Krithika, Bhatnagar, Suyash, Reifman, Jaques, Prigge, Sean T., Vaidya, Akhil B., Wallqvist, Anders

Source: Malaria Journal; 2/14/2023, Vol. 21 Issue 1, p1-17, 17p, 2 Diagrams, 3 Charts, 5 Graphs

Malaria Pulls a FASt One

Authors: Spalding, Maroya D., Prigge, Sean T.

Source: In Cell Host & Microbe 2008 4(6):509-511