Plant extracts modulate cellular stress to inhibit replication of mouse Coronavirus MHV-A59

Authors: Prieto, Karol ¹, Arévalo, Cindy ¹, Lasso, Paola, Carlosama, Carolina, Urueña, Claudia, Fiorentino, Susana, Barreto, Alfonso ^∗

Source: In Heliyon 15 January 2024 10(1)

Plant extract from Caesalpinia spinosa inhibits cancer-associated fibroblast-like cells generation and function in a tumor microenvironment model

Authors: Jiménez, Maria Camila ¹, Prieto, Karol ¹, Lasso, Paola, Gutiérrez, Melisa, Rodriguez-Pardo, Viviana, Fiorentino, Susana, Barreto, Alfonso ^∗

Source: In Heliyon March 2023 9(3)

Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

Authors: Mandula, Jessica K., Chang, Shiun, Mohamed, Eslam, Jimenez, Rachel, Sierra-Mondragon, Rosa A., Chang, Darwin C., Obermayer, Alyssa N., Moran-Segura, Carlos M., Das, Satyajit, Vazquez-Martinez, Julio A., Prieto, Karol, Chen, Ann, Smalley, Keiran S.M., Czerniecki, Brian, Forsyth, Peter, Koya, Richard C., Ruffell, Brian, Cubillos-Ruiz, Juan R., Munn, David H., Shaw, Timothy I., Conejo-Garcia, Jose R., Rodriguez, Paulo C.

Source: In Cancer Cell 10 October 2022 40(10):1145-1160

Immunodeficiency in a Patient with 22q11.2 Distal Deletion Syndrome and a p.Ala7dup Variant in the MAPK1 Gene

Authors: Sánchez, Ana I., García-Acero, Mary A., Paredes, Angela, Quero, Rossi, Ortega, Rita I., Rojas, Jorge A., Herrera, Daniel, Parra, Miguel, Prieto, Karol, Ángel, Juana, Rodríguez, Luz-Stella, Prieto, Juan C., Franco, Manuel

Source: Molecular syndromology. 11(1):15-23

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099749720.0x000001&indx=1&recIds=ETOCvdc_100099749720.0x000001

The delay in cell death caused by the induction of autophagy by P2Et extract is essential for the generation of immunogenic signals in melanoma cells

Authors: Prieto, Karol, Lozano, Maria Paula, Urueña, Claudia, Alméciga-Díaz, Carlos Javier, Fiorentino, Susana, Barreto, Alfonso

Source: Apoptosis. 25(11-12):875-888

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187135059.0x000001&indx=1&recIds=ETOCvdc_100187135059.0x000001

Polyphenol-rich extract induces apoptosis with immunogenic markers in melanoma cells through the ER stress-associated kinase PERK

Authors: Prieto, Karol [and others]

Source: Cell death discovery. 5(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190561567.0x000001&indx=1&recIds=ETOCvdc_100190561567.0x000001

Development of a MEK inhibitor, NFX-179, as a chemoprevention agent for squamous cell carcinoma.

Authors: Sarin, Kavita Y., Kincaid, John, Sell, Brittney, Shahryari, Jahanbanoo, Duncton, Matthew A. J., Morefield, Elaine, Sun, Wenchao, Prieto, Karol, Chavez-Chiang, Omar, de Moran Segura, Carlos, Nguyen, Jonathan, Bronson, Roderick T., Plotkin, Scott R., Kochendoerfer, Gerd G., Fenn, Peter, Wootton, Michael A., Powala, Christopher, de Souza, Mark P., Tsai, Kenneth Y.

Source: Science Translational Medicine; 10/11/2023, Vol. 15 Issue 717, p1-10, 10p

Subject Terms: ACTINIC keratosis, SQUAMOUS cell carcinoma, CHEMOPREVENTION, TOPICAL drug administration, MITOGEN-activated protein kinases, SKIN cancer

Microbiome modulates immunotherapy response in cutaneous squamous cell carcinoma.

Authors: Voigt, Anita Y., Walter, Andrew, Young, Timothy H., Graham, John P., Batista Bittencourt, Bruna M., de Mingo Pulido, Alvaro, Prieto, Karol, Tsai, Kenneth Y., Sundberg, John P., Oh, Julia

Source: Experimental Dermatology; Oct2023, Vol. 32 Issue 10, p1624-1632, 9p

Subject Terms: SQUAMOUS cell carcinoma, IMMUNE checkpoint inhibitors, IMMUNOTHERAPY, GUT microbiome, SKIN cancer

Modulation of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment by Natural Products.

Authors: Calderon, Jhon Jairo, Prieto, Karol, Lasso, Paola, Fiorentino, Susana, Barreto, Alfonso

Source: Archivum Immunologiae & Therapiae Experimentalis; 7/6/2023, Vol. 71 Issue 1, p1-16, 16p

Regulatory Role of the RUNX2 Transcription Factor in Lung Cancer Apoptosis.

Authors: Bernal, Camila, Otalora, Andrea, Cañas, Alejandra, Barreto, Alfonso, Prieto, Karol, Montecino, Martin, Rojas, Adriana

Source: International Journal of Cell Biology; 12/3/2022, Vol. 2022, p1-13, 13p

Subject Terms: TRANSCRIPTION factors, LUNG cancer, APOPTOSIS inhibition, GENETIC overexpression, EMBRYOLOGY, WNT signal transduction

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Niveles de homocisteína y polimorfismos de los genes de la MTHFR y la CBS en pacientes colombianos con trombosis venosa superficial y profunda. (Spanish)

Alternate Title: Homocysteine levels and polymorphisms of MTHFR and CBS genes in Colombian patients with superficial and deep venous thrombosis. (English)

Authors: Ayala, Claudia, García, Reggie, Cruz, Edith, Prieto, Karol, Bermúdez, Marta

Source: Biomédica: Revista del Instituto Nacional de Salud; jun2010, Vol. 30 Issue 2, p259-267, 9p, 4 Charts

Subject Terms: HOMOCYSTEINE, GENETIC polymorphisms, VENOUS thrombosis, BLOOD vessels, METHYLENETETRAHYDROFOLATE reductase

Geographic Terms: COLOMBIA

Análisis descriptivo de los niveles de homocisteína, polimorfismos C699T, C1080T y 844Ins68pb de la CBS, C677T de la MTHFR y otros factores de riesgo cardiovascular en una población colombiana con síndrome coronario agudo. (Spanish)

Alternate Title: Descriptive analysis of homocysteine levels, polymorphisms C699T, C1080T and 844Ins68pb of CBS, C677T from the MTHFR, and other cardiovascular risk factors in a Colombian population with acute coronary syndrome. (English)

Authors: PRIETO, KAROL, GARCÍA, REGGIE, BERNAL, JAIME, BERMÉDEZ, MARTHA

Source: Universitas Médica; jul-sep2009, Vol. 50 Issue 3, p322-334, 13p, 3 Charts

Subject Terms: CARDIOVASCULAR disease diagnosis, GENETIC polymorphisms, HOMOCYSTEINE, VITAMIN B12, FOLIC acid, HEALTH surveys

Geographic Terms: COLOMBIA