Chapter Structural Insight into Regulation of the Proteasome Ub-Receptor Rpn10

Authors: Kleifeld, Oded, Levin-Kravets, Olga, Prag, Gali, Ben-Aroya, Shay, Attali, Ilan, Keren-Kaplan, Tal

Subject Terms: ubiquitin receptor, crystal structure, ubiquitylated ubiquitin receptor, regulation mechanisms, cargo shuttle, Biochemistry

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Access URL: https://library.oapen.org/handle/20.500.12657/49334

Dithiothreitol-based protein equalisation in the context of multiple myeloma: Enhancing proteomic analysis and therapeutic insights

Authors: Domingos, Ines F., Carvalho, Luis B., Lodeiro, Carlos, Gerivaz, Rita, Prag, Gali, Micaglio, Emanuele, Muchtar, Eli, Santos, Hugo M., Capelo, Jose L.

Source: In Talanta 1 November 2024 279

TMEM16F regulates pathologic α‐synuclein secretion and spread in cellular and mouse models of Parkinson's disease.

Authors: Cohen‐Adiv, Stav, Amer‐Sarsour, Fatima, Berdichevsky, Yevgeny, Boxer, Emily, Goldstein, Orly, Gana‐Weisz, Mali, Tripathi, Utkarsh, Rike, Wote Amelo, Prag, Gali, Gurevich, Tanya, Giladi, Nir, Stern, Shani, Orr‐Urtreger, Avi, Friedmann‐Morvinski, Dinorah, Ashkenazi, Avraham

Source: Aging Cell; Feb2025, Vol. 24 Issue 2, p1-19, 19p

Split Chloramphenicol Acetyl-Transferase Assay Reveals Self-Ubiquitylation-Dependent Regulation of UBE3B

Authors: Levin-Kravets, Olga, Kordonsky, Alina, Shusterman, Anna, Biswas, Sagnik, Persaud, Avinash, Elias, Sivan, Langut, Yael, Florentin, Amir, Simpson-Lavy, Kobi J., Yariv, Elon, Avishid, Reut, Sror, Mor, Almog, Ofir, Marshanski, Tal, kadosh, Shira, Ben David, Nicole, Manori, Bar, Fischer, Zohar, Lilly, Jeremiah, Borisova, Ekaterina, Ambrozkiewicz, Mateusz C., Tarabykin, Victor, Kupiec, Martin, Thaker, Maulik, Rotin, Daniela, Prag, Gali

Source: In Journal of Molecular Biology 19 November 2021 433(23)

Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions.

Authors: Kordonsky, Alina, Gabay, Matan, Rosinoff, Aurelia, Avishid, Reut, Flornetin, Amir, Deouell, Noam, Abd Alkhaleq, Taimaa, Efron, Noa, Milshtein, Shoham, Shifman, Julia M., Gal, Maayan, Prag, Gali

Source: International Journal of Molecular Sciences; Oct2024, Vol. 25 Issue 20, p11099, 12p

Subject Terms: UBIQUITIN, ACETYLTRANSFERASES, MUTAGENESIS, CHLORAMPHENICOL, PROTEINS

Ubiquitin Signaling and Degradation of Aggregate-Prone Proteins

Authors: Galves, Margarita, Rathi, Ritu, Prag, Gali, Ashkenazi, Avraham

Source: In Trends in Biochemical Sciences October 2019 44(10):872-884

RING/U-box E3 protein BIR1 interacts with and ubiquitinates barley growth repressor BROAD LEAF1.

Authors: Soltani, Ouad, Jöst, Moritz, Hoffie, Iris, Hensel, Götz, Kappel, Christian, Prag, Gali, McKim, Sarah, Kumlehn, Jochen, Lenhard, Michael

Source: Plant Physiology; Sep2024, Vol. 196 Issue 1, p228-243, 16p

K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins.

Authors: Magits, Wout, Steklov, Mikhail, Jang, Hyunbum, Sewduth, Raj N, Florentin, Amir, Lechat, Benoit, Sheryazdanova, Aidana, Zhang, Mingzhen, Simicek, Michal, Prag, Gali, Nussinov, Ruth, Sablina, Anna

Source: EMBO Journal; Jul2024, Vol. 43 Issue 14, p2862-2877, 16p

Subject Terms: GTPASE-activating protein, RAS proteins, RAS oncogenes, POST-translational modification, CANCER cell growth, UBIQUITINATION, CARRIER proteins

Structural Mechanism for Ubiquitinated-Cargo Recognition by the Golgi-Localized, γ-Ear-Containing, ADP-Ribosylation-Factor-Binding Proteins

Authors: Prag, Gali, Lee, Sangho, Mattera, Rafael, Arighi, Cecilia N., Beach, Bridgette M., Bonifacino, Juan S., Hurley, James H., Davies, David R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Feb . 102(7), 2334-2339.

Access URL: https://www.jstor.org/stable/3374615

A mutagenesis analysis of Tim50, the major receptor of the TIM23 complex, identifies regions that affect its interaction with Tim23

Authors: Dayan, Dana, Bandel, May, Günsel, Umut, Nussbaum, Inbal, Prag, Gali, Mokranjac, Dejana, Neupert, Walter, Azem, Abdussalam

Source: Scientific reports. 9(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112270965.0x000001&indx=1&recIds=ETOCvdc_100112270965.0x000001

Regulation of the anaphase promoting complex/cyclosome by the degradation of its unassembled catalytic subunit, Apc11

Authors: Volpe, Marina, Levinton, Nelly, Rosenstein, Nethanel, Prag, Gali, Ben‐Aroya, And Shay

Source: FASEB journal. 33(9):9752-9761

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100103214960.0x000001&indx=1&recIds=ETOCvdc_100103214960.0x000001

Chapter Structural Insight into Regulation of the Proteasome Ub-Receptor Rpn10

Authors: Kleifeld, Oded, Levin-Kravets, Olga, Prag, Gali, Ben-Aroya, Shay, Attali, Ilan, Keren-Kaplan, Tal

Subject Terms: ubiquitin receptor, crystal structure, ubiquitylated ubiquitin receptor, regulation mechanisms, cargo shuttle, Biochemistry

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CRL4^DCAF1 ubiquitin ligase regulates PLK4 protein levels to prevent premature centriole duplication.

Authors: Grossmann, Josina, Kratz, Anne-Sophie, Kordonsky, Alina, Prag, Gali, Hoffmann, Ingrid

Source: Life Science Alliance; Jun2024, Vol. 7 Issue 6, p1-17, 17p

Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination.

Authors: Amer-Sarsour, Fatima, Falik, Daniel, Berdichevsky, Yevgeny, Kordonsky, Alina, Eid, Sharbel, Rabinski, Tatiana, Ishtayeh, Hasan, Cohen-Adiv, Stav, Braverman, Itzhak, Blumen, Sergiu C., Laviv, Tal, Prag, Gali, Vatine, Gad D., Ashkenazi, Avraham

Source: EMBO Journal; 1/16/2024, Vol. 43 Issue 2, p250-276, 27p

Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.

Authors: Rotin, Daniela^1,2 drotin@sickkids.ca, Prag, Gali^3,4 prag@tauex.tau.ac.il

Source: Physiology. Jan2024, Vol. 39 Issue 1, p18-29. 12p.

Subject Terms: *UBIQUITIN ligases, *ION channels, *HUMAN physiology, *ENZYMES, *UBIQUITIN

Deubiquitylating enzymes in neuronal health and disease

Authors: Amer-Sarsour, Fatima, Kordonsky, Alina, Berdichevsky, Yevgeny, Prag, Gali, Ashkenazi, Avraham

Source: Cell death and disease. 12(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193205261.0x000001&indx=1&recIds=ETOCvdc_100193205261.0x000001

Ubiquitylation‐dependent oligomerization regulates activity of Nedd4 ligases

Authors: Attali, Ilan, Tobelaim, William Sam, Persaud, Avinash, Motamedchaboki, Khatereh, Simpson‐Lavy, Kobi J, Mashahreh, Bayan, Levin‐Kravets, Olga, Keren‐Kaplan, Tal, Pilzer, Inbar, Kupiec, Martin, Wiener, Reuven, Wolf, Dieter A, Rotin, Daniela, Prag, Gali

Source: EMBO journal. 36(4):425-440

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186097860.0x000001&indx=1&recIds=ETOCvdc_100186097860.0x000001

Tetrameric Assembly of Monoubiquitin Accurately Mimics the Lys11 Polyubiquitin Chain Structure

Authors: Levin-Kravets, Olga, Shohat, Noa, Prag, Gali

Source: Biochemistry. 54(30):4704-4710

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN602283444&indx=1&recIds=ETOCRN602283444

The Vps27/Hse1 Complex Is a GAT Domain-Based Scaffold for Ubiquitin-Dependent Sorting

Authors: Prag, Gali, Watson, Hadiya, Kim, Young C., Beach, Bridgette M., Ghirlando, Rodolfo, Hummer, Gerhard, Bonifacino, Juan S., Hurley, James H.

Source: In Developmental Cell 2007 12(6):973-986

Mechanism of Ubiquitin Recognition by the CUE Domain of Vps9p.

Authors: Prag, Gali, Misra, Saurav, Jones, Eudora A.

Source: Cell; May 30 2003, Vol. 113 Issue 5, p609-620, 12p